Clin Nutr March 2021 PMID 32723506

Association between dietary fat intake and mortality from all-causes, cardiovascular disease, and cancer: A systematic review and meta-analysis of prospective cohort studies.

Youngyo Kim, Youjin Je, Edward L Giovannucci

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Mentions

47
Peak: 4 in May 2024
across 5 sources since Jul 2020

Extended reach

24,911
potential audience

Total likes

48

Video views

225

Mentions per month

Jul 2020 – May 2025

Where it's discussed

  • X / Twitter27 posts
  • News14 articles
  • YouTube2 videos
  • Facebook2 posts
  • Reddit2 posts

AI synopsis

What people are saying

The discussions reflect a strong agreement with the meta-analysis results, citing its large sample size and relevance for public health, as seen in posts emphasizing the link between saturated fats and mortality. The tone varies from supportive to skeptical, with some posts debating the validity and applications of the findings, indicating active engagement and perceived significance.

AgreementStrong agreement

Most discussions concur with the study's findings that higher saturated fat intake correlates with increased mortality, reflecting strong consensus.

InterestHigh interest

Discussions show high curiosity and focus on the data's implications, with many citing the large sample size and debate on dietary recommendations.

EngagementModerate engagement

Users actively reference the methodology and implications of the meta-analysis, engaging through questions and contrasting views.

ImpactHigh impact

The discussions influence perspectives on diet and health, with some posts suggesting policy or dietary changes based on the findings.

Abstract in brief

  • This meta-analysis reviewed 19 prospective cohort studies with over 1 million participants to explore how different types of dietary fats relate to death from all causes, heart disease, and cancer, finding that higher intake of saturated and trans fats increases mortality risk, while higher polyunsaturated and monounsaturated fats are linked to lower risk.
  • The study showed that even small increases (around 5% of energy intake) in polyunsaturated and monounsaturated fats are associated with reduced risk of death, whereas increases in saturated fat raise the risk of mortality, especially with intakes above 11% of energy.
  • Overall, diets high in saturated and trans fats are connected to increased mortality from all causes, heart disease, and cancer, while consuming more polyunsaturated and monounsaturated fats appears to have protective effects.]

Top posts

Most liked on X and Bluesky
galaxysplain
@galaxysplain · X

Meta of cohorts on dietary fat intake & mortality from all-causes, cardiovascular disease & cancer (2021) Higher MUFA & PUFA intake & lower saturated fat intake (when below 11% of total calories) associate with lower all cause mortality. https://t.co/fRBjwKKH9t https://t.co/iJq23yIior

Mar 8, 2022 · 14 likes · 1 share · 490 followers View post →
David Morales-Álamo
@D_Morales_Alamo · X

Association between dietary fat intake and mortality from all-causes, cardiovascular disease, and cancer: A systematic review and meta-analysis of prospective cohort studies | published in Clinical Nutrition | https://t.co/NEB84xPyrl

Jan 29, 2023 · 10 likes · 2 shares · 3,757 followers View post →
ZahcM
@ZahcM · X

"Association between dietary fat intake and mortality from all-causes, cardiovascular disease, and cancer: A systematic review and meta-analysis of prospective cohort studies" - https://t.co/3otXN6rNle More baseless attacks on saturated fat

Jul 16, 2020 · 4 likes · 1,916 followers View post →
James At The N
@nx_frontier · X

https://t.co/jm5WJE9GYk.

May 14, 2024 · 1 like · 2,349 followers View post →
Alex Süssmann
@alexsussmann · X

@EvolvedRD @BioLayne May wanna consider real data to determine the truth. https://t.co/51gRB15gMQ

Mar 10, 2022 · 1 like · 466 followers View post →
nuni
@armycomunista · X

@tropicswizard @GrataoThamara essa é uma das maiores meta-análises disponíveis, ela analisou mais de 1 milhão de pessoas e concluiu que dietas ricas em gordura saturada estão associadas a maior mortalidade por doenças cardiovasculares e câncer https://t.co/th8bK0rbdZ

Jun 8, 2024 · 1 like · 81 followers View post →

All mentions

Tejas Kadaskar
@TejasKadaskar · X

Systematic Review & Meta-Analysis (2020) https://t.co/7nMov3WH3e

May 17, 2025 · 415 followers View post →
Age Friendly
@Dakota_GWEP · X

Cardiovascular disease is the leading cause of death in the United States (https://t.co/jenk2QKThp), and saturated fats increase one’s risk of cardiovascular disease (https://t.co/lZlWMOqIa7). https://t.co/TNSx3f06ge

Oct 22, 2024 · 148 followers View post →
Larsⓥ
@KampLkamp · X

@RixAutomatedMat @bjoernstengel @HubertAiwanger So funktioniert Wissenschaft nicht - zumindest außerhalb Deines Stammtischs. Es gibt keine Autoritäten sondern Erkenntnisse und Evidenz, welche die Realität jeweils am besten abbilden und Vorhersagen treffen kann. Es steht Dir frei, Studien zu widerlegen. https://t.co/4BwQ4DksDn

Aug 3, 2024 · 97 followers View post →
د. أحمد
@AMK__5 · X

@Bo_K70 https://t.co/zZwJdZc99O https://t.co/O6eqn3c8na

Jul 3, 2024 · 242 followers View post →
nuni
@armycomunista · X

@tropicswizard @GrataoThamara essa é uma das maiores meta-análises disponíveis, ela analisou mais de 1 milhão de pessoas e concluiu que dietas ricas em gordura saturada estão associadas a maior mortalidade por doenças cardiovasculares e câncer https://t.co/th8bK0rbdZ

Jun 8, 2024 · 1 like · 81 followers View post →
☭ Ⓥ Stalin did nothing wrong
@squirrelpalooza · X

@OMMFoundation @PlantBasedNews https://t.co/BMbsOjRqxh

May 14, 2024 · 3,765 followers View post →
James At The N
@nx_frontier · X

@veganpragmatism @gaiashining https://t.co/jm5WJE9GYk.

May 14, 2024 · 2,349 followers View post →
James At The N
@nx_frontier · X

https://t.co/jm5WJE9GYk.

May 14, 2024 · 1 like · 2,349 followers View post →
Ronn
@Ron31746880 · X

@Mangan150 This does concern me: https://t.co/nbzqJ4zvVE

Jan 21, 2024 · 1 followers View post →
Ronn
@Ron31746880 · X

@Mangan150 How do you reconcile that based on this systematic review concerning saturated fat inover 1 million individuals? https://t.co/nbzqJ4zvVE

Dec 15, 2023 · 1 like · 1 followers View post →
Ronn
@Ron31746880 · X

@raynman01 @Mangan150 How do you reconcile that based on this systematic review of over 1 million individuals as it pertains to saturated fat? https://t.co/nbzqJ4zvVE

Dec 15, 2023 · 1 followers View post →
Lauri Kärnä
@LauriKrn · X

@TuckerGoodrich Talks about fumes only so that study is worthless. Here’s a meta-analysis: https://t.co/vgxmTLkutM No increase in cancer rates. Another: Decreased cancer mortality https://t.co/bv2TJEZ7vA

Oct 26, 2023 · 18 followers View post →
Earthling
@_earthling74 · X

@robertlufkinmd https://t.co/QjH24qDHAy https://t.co/MnKbzrOu0q https://t.co/nGIGlWAL5N https://t.co/QNV4DAQHk5 https://t.co/Bg4tYkija8 https://t.co/0t8OobUsol https://t.co/mg6i8mjzib

Aug 17, 2023 · 429 followers View post →
R Pell
@rpellny · X

@WeiZhangAtmos @AlpacaAurelius "Diets high in saturated fat were associated with higher mortality from all-causes, CVD, and cancer, whereas diets high in polyunsaturated fat were associated with lower mortality from all-causes, CVD, and cancer." - https://t.co/sybnKl8G5U

Jul 28, 2023 · 46 followers View post →
Jayden Anker
@JaydenAnker1 · X

@TuckerGoodrich 1. Fermented dairy reduce risk 2. Saturated fat is better than refined CHO, skews effect. 3. Pufa and Mufa reduce risk. https://t.co/C6eQzVvOnT

May 30, 2023 · 35 followers View post →
Nakisa Soltani
@nakisasoltanii · X

RT @D_Morales_Alamo: Association between dietary fat intake and mortality from all-causes, cardiovascular disease, and cancer: A systematic…

Jan 31, 2023 · 2 shares · 3 followers View post →
José Antonio Benítez Muñoz
@jabenitezm4 · X

RT @D_Morales_Alamo: Association between dietary fat intake and mortality from all-causes, cardiovascular disease, and cancer: A systematic…

Jan 29, 2023 · 2 shares · 435 followers View post →
David Morales-Álamo
@D_Morales_Alamo · X

Association between dietary fat intake and mortality from all-causes, cardiovascular disease, and cancer: A systematic review and meta-analysis of prospective cohort studies | published in Clinical Nutrition | https://t.co/NEB84xPyrl

Jan 29, 2023 · 10 likes · 2 shares · 3,757 followers View post →
Bernie Simon
@Jinzang · X

@MasalaFry69 @RickCollinsEsq "Diets high in saturated fat were associated with higher mortality from all-causes, CVD, and cancer, whereas diets high in polyunsaturated fat were associated with lower mortality from all-causes, CVD, and cancer." https://t.co/6K1ob6ePBv

Dec 9, 2022 · 454 followers View post →
Bogdan Drăgănescu
@bogdragan · X

@der_lahme @RDValerie "Conclusions: Diets high in saturated fat were associated with higher mortality from all-causes, CVD, and cancer, whereas diets high in polyunsaturated fat were associated with lower mortality from all-causes, CVD, and cancer." https://t.co/NAHTjVCGzv

Jul 22, 2022 · 361 followers View post →
Annie Leymarie
@AnnieLeymarie · X

@PeterFaberSP @dr_cois Here, a commentary on another recent meta-analysis https://t.co/uKu4sjgI69 - and now I must leave this conversation! https://t.co/daa4ApmFKS

Apr 11, 2022 · 2,008 followers View post →
Alex Süssmann
@alexsussmann · X

@EvolvedRD @BioLayne May wanna consider real data to determine the truth. https://t.co/51gRB15gMQ

Mar 10, 2022 · 1 like · 466 followers View post →
Fusion Prog Guy @ fusionprogguy.bsky.social
@FusionProgGuy · X

RT @Alecsplaining: Meta of cohorts on dietary fat intake & mortality from all-causes, cardiovascular disease & cancer (2021) Higher MUFA &…

Mar 9, 2022 · 1 share · 1,586 followers View post →
galaxysplain
@galaxysplain · X

Meta of cohorts on dietary fat intake & mortality from all-causes, cardiovascular disease & cancer (2021) Higher MUFA & PUFA intake & lower saturated fat intake (when below 11% of total calories) associate with lower all cause mortality. https://t.co/fRBjwKKH9t https://t.co/iJq23yIior

Mar 8, 2022 · 14 likes · 1 share · 490 followers View post →
INDoximity
@indoximity · X

Comment on “Association between dietary fat intake and mortality from all-causes, cardiovascular disease, and cancer: A systematic review and meta-analysis of prospective cohort studies” https://t.co/aN9lMBHZix #ClinicalNutrition #Nutrition

Dec 1, 2021 · 832 followers View post →
Shaun Ward
@MyNutritionSci · X

@DrPaulMason @TheBhupiThakur @ScepticalDoctor @kevinnbass @AviBittMD @bigfatsurprise @eatmostlyfatali @LDLSkeptic @ProfTimNoakes @The_Nutrivore @dylanarmbruste3 @MattMadore576 @NutritionMadeS3 Check Avis reply, but here's a new study to add... https://t.co/7orc8xn28I

Apr 20, 2021 · 2,386 followers View post →
ZahcM
@ZahcM · X

"Association between dietary fat intake and mortality from all-causes, cardiovascular disease, and cancer: A systematic review and meta-analysis of prospective cohort studies" - https://t.co/3otXN6rNle More baseless attacks on saturated fat

Jul 16, 2020 · 4 likes · 1,916 followers View post →