Cell July 2020 PMID 32758418

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis.

Sho Kitamoto, Hiroko Nagao-Kitamoto, Yizu Jiao, Merritt G Gillilland, Atsushi Hayashi, Jin Imai, Kohei Sugihara, Mao Miyoshi, Jennifer C Brazil, Peter Kuffa, Brett D Hill, Syed M Rizvi, Fei Wen, Shrinivas Bishu, Naohiro Inohara

Mentions

90
Peak: 37 in Jun 2020
across 6 sources since Jun 2020

Extended reach

691,564
potential audience

Total likes

118

Video views

1,254

Mentions per month

Jun 2020 – Nov 2025

Where it's discussed

  • X / Twitter60 posts
  • Facebook20 posts
  • News6 articles
  • YouTube2 videos
  • TikTok1 posts
  • Blogs1 articles

AI synopsis

What people are saying

Overall, the discussions show strong agreement with the importance of the study, with numerous mentions of Th17 cells migrating from oral inflammation to the gut and the role of oral bacteria, paired with enthusiastic phrases like 'very interesting paper' and 'strong intermucosal connection,' which reflect both high interest and engagement. The tone and focus on immune pathways and microbiome connections highlight the perceived relevance and potential impact of this research.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, especially highlighting the findings on immune cell migration and oral-gut microbiome links.

InterestHigh interest

The extensive sharing and positive remarks demonstrate high curiosity and recognition of the study’s importance.

EngagementHigh engagement

Discussions include references to specific immune mechanisms and broader implications, indicating deep analysis.

ImpactModerate impact

While many see the findings as impactful, some comments focus just on the novelty rather than concrete applications.

Abstract in brief

  • The study investigates how oral infections, specifically periodontal inflammation, worsen gut inflammation, linking oral and gut health.
  • Periodontitis leads to an increase in harmful bacteria in the mouth, which can enter the gut and trigger inflammation through immune responses.
  • Additionally, immune cells (Th17 cells) reactive to these oral bacteria migrate to the inflamed gut, causing further inflammation and potentially leading to conditions like colitis.

Top posts

Most liked on X and Bluesky
Cell
@CellCellPress · X

New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/UhxX1FuhyR

Jun 16, 2020 · 43 likes · 15 shares · 264,446 followers View post →
John Lukens
@LukensJohnR · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/2zHpfcJb3K

Jun 16, 2020 · 15 likes · 3 shares · 14,220 followers View post →
Doran Lab
@KdoranLab · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis: Cell https://t.co/ixvNHiNCen

Aug 15, 2020 · 7 likes · 1 share · 3,550 followers View post →
Pranab Mukherjee
@pranab_IBD · X

Very interesting paper. The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/WwqRoR8oaw ⁦@IBD_FloMD⁩ ⁦@JChandra_IBD⁩ ⁦@JiannanliMDPhD⁩

Jun 17, 2020 · 6 likes · 4 shares · 211 followers View post →
Cell
@CellCellPress · X

Article in this issue of Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis - https://t.co/UhxX1FuhyR

Jul 23, 2020 · 4 likes · 264,446 followers View post →
Graham Britton
@grahambiota · X

A little late to this one, but this @CellCellPress is

Aug 17, 2020 · 4 likes · 339 followers View post →

All mentions

Yoshifumi Murakami
@Leo238umi · X

①

Feb 3, 2024 · 53 followers View post →
早房一平
@hayabusa_ippei · X

RT @ma31stm: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis. https://t.co/jqMij3P4fH https://…

Jun 23, 2021 · 1 share · 1,379 followers View post →
まつこ
@ma31stm · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis. https://t.co/jqMij3P4fH https://t.co/OU0GyOSSH8

Jun 23, 2021 · 1 share · 2,248 followers View post →
RRID Robot
@RobotRrid · X

The authors of "The Intermucosal Connection between the Mouth and…" (https://t.co/x5Mgxdle7G) included RRIDs in their paper! Thank you for making your #methodsmatter. #ReproducibleResearch

Apr 24, 2021 · 161 followers View post →
pochi
@unattened_bag · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/LdXF3H2mrF

Apr 2, 2021 · 263 followers View post →
タツさん実験中@奏でる細胞
@TatsuKono · X

RT @uja_info: 口-腸粘膜免疫のクロストークから紐解く腸炎増悪メカニズム 掲載雑誌:Cell 論文リンクはこちらです。https://t.co/F4ABKuirWx

Apr 1, 2021 · 1 share · 1,306 followers View post →
海外日本人研究者ネットワーク(UJA)
@uja_info · X

口-腸粘膜免疫のクロストークから紐解く腸炎増悪メカニズム 掲載雑誌:Cell 論文リンクはこちらです。https://t.co/F4ABKuirWx

Apr 1, 2021 · 2 likes · 1 share · 4,619 followers View post →
Graham Britton
@grahambiota · X

A little late to this one, but this @CellCellPress is

Aug 17, 2020 · 4 likes · 339 followers View post →
Melody Smith, MD, MS
@MelodySmithMD · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/F5O3TzC4t6

Aug 15, 2020 · 1 like · 1,311 followers View post →
Mucosal Immunology and Biology Research Center
@MGH_Mucosalists · X

RT @KdoranLab: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis: Cell https://t.co/ixvNHiNCen

Aug 15, 2020 · 1 share · 666 followers View post →
Doran Lab
@KdoranLab · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis: Cell https://t.co/ixvNHiNCen

Aug 15, 2020 · 7 likes · 1 share · 3,550 followers View post →
IKMB_BioInfoGen
@BioInfoGen1 · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis: Cell https://t.co/bUjX8BQPjb

Aug 15, 2020 · 176 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/sJ9hQMs8zA

Aug 11, 2020 · 2,240 followers View post →
micropapers
@micro_papers · X

C/ The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis. https://t.co/kaSVoogBlD

Aug 8, 2020 · 331 followers View post →
Davide Pietropaoli DDS, PhD
@periopaoli · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis. https://t.co/CbTz4n9WSZ

Aug 8, 2020 · 30 followers View post →
Symbiosis papers
@Symbiosispapers · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis. https://t.co/2J2dIQgg6t

Aug 8, 2020 · 1,104 followers View post →
Jose L Galaz
@jlgalaz · X

RT @gamonasterioo: Oral pathobiont-reactive Th17 cells can migrate to the gut after Oral inflammation and contribute to Colitis. Strong #Or…

Jul 28, 2020 · 2 shares · 893 followers View post →
Cell
@CellCellPress · X

Article in this issue of Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis - https://t.co/UhxX1FuhyR

Jul 23, 2020 · 4 likes · 264,446 followers View post →
EFP
@PerioEurope · X

The intermucosal connection between the mouth and gut in commensal pathobiont-driven colitis - read the article written by Sho Kitamoto et al in 'Cell'. #EFPerio #periodontology https://t.co/8xVazzKDgp

Jul 15, 2020 · 3,493 followers View post →
Juan Antonio Martinez
@juanmtzsegura · X

RT @sepdigestiva:

Jul 14, 2020 · 3 shares · 57 followers View post →
Iris Torrente | Colitis Ulcerosa & Inmunomediadas
@Iris_CU93 · X

RT @sepdigestiva:

Jul 14, 2020 · 3 shares · 6,393 followers View post →
Bryan Priego MD, PhD
@BryanPriegoP · X

RT @sepdigestiva:

Jul 14, 2020 · 3 shares · 2,462 followers View post →
Sociedad Española de Patología Digestiva (SEPD)
@sepdigestiva · X

Jul 14, 2020 · 3 likes · 3 shares · 23,486 followers View post →
Marcel van den Brink
@DrMvandenBrink · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis: Cell https://t.co/fh8bdCACbV

Jun 19, 2020 · 3 likes · 8,734 followers View post →
Pᴀᴏʟᴀ Rᴏᴅʀɪɢᴜᴇᴢ Gɪᴜsᴛɪɴɪᴀɴɪ
@PaoGiusti · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/3peA7InwqZ https://t.co/SfREafuT7Y

Jun 18, 2020 · 4,251 followers View post →
高等夢眠
@NobuKoba1988 · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/QAxTN9S5UE 鎌田先生のとこジャン

Jun 18, 2020 · 2 likes · 8,619 followers View post →
Saubashya Sur, PhD
@SaubashyaSur · X

RT @hlcao: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis: Cell https://t.co/UfPDik6rJ7

Jun 17, 2020 · 1 share · 787 followers View post →
Huiluo Cao 曹慧荦
@hlcao · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis: Cell https://t.co/UfPDik6rJ7

Jun 17, 2020 · 1 share · 2,840 followers View post →
AnonRere
@AnonRere · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/HycQmgXhI8

Jun 17, 2020 · 2,211 followers View post →
PF Anderson @pfanderson@disabled.social
@pfanderson · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis <https://t.co/L55vtopuaL> #umich #microbiome

Jun 17, 2020 · 10,771 followers View post →
Johana Tello
@JOHANATELLO · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis #inflammation #gut #pathobionts https://t.co/9yV5AC9rG8

Jun 17, 2020 · 307 followers View post →
Waggoner Lab
@LabWaggoner · X

RT @LukensJohnR: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/2zHpfcJb3K

Jun 17, 2020 · 3 shares · 11,680 followers View post →
Mindy Engevik
@micromindy · X

RT @pranab_IBD: Very interesting paper. The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https:…

Jun 17, 2020 · 4 shares · 3,343 followers View post →
ImmunoLatinXs "Científicos Comunicando Ciencia"
@ImmunoLatinXs · X

RT @infdisease_news: What's the intermucosal connection between the mouth and gut in commensal pathobiont-driven #colitis?

Jun 17, 2020 · 2 shares · 1,563 followers View post →
Jyotsna Chandra, Ph.D.
@JChandra_IBD · X

RT @pranab_IBD: Very interesting paper. The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https:…

Jun 17, 2020 · 4 shares · 282 followers View post →
Florian Rieder
@IBD_FloMD · X

RT @pranab_IBD: Very interesting paper. The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https:…

Jun 17, 2020 · 4 shares · 6,616 followers View post →
Jiannan Li
@JiannanliMDPhD · X

RT @pranab_IBD: Very interesting paper. The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https:…

Jun 17, 2020 · 4 shares · 203 followers View post →
Pranab Mukherjee
@pranab_IBD · X

Very interesting paper. The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/WwqRoR8oaw ⁦@IBD_FloMD⁩ ⁦@JChandra_IBD⁩ ⁦@JiannanliMDPhD⁩

Jun 17, 2020 · 6 likes · 4 shares · 211 followers View post →
Dr Sofia Axelrod
@Baby__Sleep · X

RT @LukensJohnR: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/2zHpfcJb3K

Jun 17, 2020 · 3 shares · 667 followers View post →
arcanemoon
@arcanemoon2 · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 17, 2020 · 15 shares · 1 followers View post →
Ariakas Enoreth
@Aenoreth · X

RT @LukensJohnR: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/2zHpfcJb3K

Jun 16, 2020 · 3 shares · 1,010 followers View post →
Eiichiro Mori
@MoriEiichiro · X

A new article from Nobuhiko Kamada lab at University of Michigan (@UMich ), showing the intermucosal connection between the mouth and gut in commensal pathobiont-driven colitis. https://t.co/67qeDRF0eq

Jun 16, 2020 · 1,968 followers View post →
Immunology of Infectious Disease News
@infdisease_news · X

What's the intermucosal connection between the mouth and gut in commensal pathobiont-driven #colitis?

Jun 16, 2020 · 1 like · 2 shares · 12,646 followers View post →
Nicolas Dutzan
@ndutzan · X

RT @gamonasterioo: Oral pathobiont-reactive Th17 cells can migrate to the gut after Oral inflammation and contribute to Colitis. Strong #Or…

Jun 16, 2020 · 2 shares · 341 followers View post →
John Lukens
@LukensJohnR · X

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/2zHpfcJb3K

Jun 16, 2020 · 15 likes · 3 shares · 14,220 followers View post →
Francesco Puzzo
@cicciopuz · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 1,432 followers View post →
David Usharauli
@3DiMMUNE · X

T cells really like to move around. "Th17 cells of oral origin can be activated by translocated oral pathobionts and cause development of colitis" The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis: Cell https://t.co/h8d36MLBHT

Jun 16, 2020 · 2 likes · 2 shares · 2,742 followers View post →
Tomoko Ikeuchi
@IkeuchiTomoko · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 5 followers View post →
Benjamin X. Wang
@BenjaminXWang1 · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 174 followers View post →
René Alfonso
@ReneAlfon_zoo · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 416 followers View post →
Microloves
@microloves · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 27 followers View post →
Eduardo Villalobo
@ptu_us_es · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 1,115 followers View post →
Hongbing Yu
@hongbing_yu · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 272 followers View post →
Alberto Caminero
@AlbertoCaminer7 · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 325 followers View post →
Marouan Zarrouk, Ph.D.
@Marozar82 · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 196 followers View post →
Kyle Flannigan
@kyle_flannigan · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 142 followers View post →
.
@gamonasterioo · X

Oral pathobiont-reactive Th17 cells can migrate to the gut after Oral inflammation and contribute to Colitis. Strong #OralGut intermucosal connection found. The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/n9vPoiOlsJ

Jun 16, 2020 · 2 likes · 2 shares · 1,659 followers View post →
Sorrell Lab
@Sorrell_Lab · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 2,011 followers View post →
Dr. pheno
@Phenomena_mw · X

RT @CellCellPress: New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Col…

Jun 16, 2020 · 15 shares · 243 followers View post →
Cell
@CellCellPress · X

New Article online now at Cell: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis https://t.co/UhxX1FuhyR

Jun 16, 2020 · 43 likes · 15 shares · 264,446 followers View post →
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