J Gastroenterol Hepatol February 2021 PMID 32810309

Systematic review with meta-analysis: The effect of vitamin E supplementation in adult patients with non-alcoholic fatty liver disease.

Andreas Vadarlis, Christina Antza, Dimitra Rafailia Bakaloudi, Ioannis Doundoulakis, Georgios Kalopitas, Myrto Samara, Theodoros Dardavessis, Theofanis Maris, Michail Chourdakis

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Mentions

22
Peak: 6 in Aug 2020
across 3 sources since Aug 2020

Extended reach

4,261,851
potential audience

Total likes

79,780

Video views

3,889,292

Mentions per month

Aug 2020 – Feb 2023

Where it's discussed

  • X / Twitter14 posts
  • News5 articles
  • YouTube3 videos

AI synopsis

What people are saying

The discussions reflect a balanced interest in the meta-analysis's findings, with many posts referencing specific outcomes like lowered liver enzymes and histological improvements, and showing active engagement through citations and historical context. The tone is analytical and cautious, emphasizing the potential therapeutic benefits while acknowledging past debates about vitamin E dosage, which shapes a moderate impact outlook.

AgreementModerate agreement

Most discussions acknowledge the positive findings of the meta-analysis, particularly regarding vitamin E's benefits for liver health and biochemical markers like ALT and AST.

InterestModerate interest

The posts demonstrate moderate interest by referencing specific parameters (e.g., liver enzymes, histological improvements) and mentioning potential clinical relevance.

EngagementHigh engagement

Several comments engage deeply by citing data from multiple studies, discussing historical concerns about vitamin E dosage, and referencing histological improvements, indicating active participation.

ImpactModerate impact

While the posts highlight the potential of vitamin E as a treatment option, the overall impact appears cautious and academic, emphasizing the need for further research and validation rather than immediate widespread change.

Abstract in brief

  • This meta-analysis examined how vitamin E supplementation affects adults with nonalcoholic fatty liver disease (NAFLD), focusing on liver enzymes, histological changes, and metabolic parameters, and found that vitamin E can significantly improve liver function and pathology.
  • The study reviewed data from eight clinical trials up to June 2020, showing that vitamin E reduced liver enzymes like ALT and AST, and improved liver tissue health, as well as lowering cholesterol, fasting blood sugar, and serum leptin levels.
  • The findings suggest that vitamin E might be a promising treatment for NAFLD, especially in cases of nonalcoholic steatohepatitis, and could be considered as a therapeutic option for managing the disease.

Top posts

Most liked on X and Bluesky
TheLiverDoc™
@theliverdr · X

1 https://t.co/4zYFjQbvOo https://t.co/FCoWT359Zb 2 https://t.co/cCD3reT7Fo 3 https://t.co/MEknkG00vd 4 https://t.co/Kav0tOeyAL 5 Old study said >/= 400 U per day caused more deaths (2005) https://t.co/bSfe2kQoLk But this was disproven (2014) https://t.co/GL40Wqr9w6

Feb 16, 2022 · 8 likes · 1 share · 314,899 followers View post →
Anuraag Jena
@DrAnuraagJ · X

Meta-analysis: The effect of vitamin E in patients with NAFLD: Improves biochemical and histological characteristics of NAFLD patients, especially of NASH patients #livertwitter https://t.co/cmvX5epPrq

Apr 9, 2021 · 8 likes · 2 shares · 4,469 followers View post →
alephh
@alephh · X

Vitamin E vs Liver enzymes in NAFLD (8-study meta-analysis) • ALT ‐7.37 IU/L • AST ‐5.71 IU/L • #VitaminE improved significantly liver pathology in every individual histologic parameter as well LDL/FBG/leptin values, especially in NASH patients https://t.co/U5oQqz7vdK

Aug 26, 2020 · 3 likes · 2 shares · 388 followers View post →
Nick Krontiris
@nick_krontiris · X

Systematic review with meta‐analysis: The effect of vitamin E supplementation in adult patients with non‐alcoholic fatty liver disease https://t.co/CCHDVB3zai #VitaminE #supplements #supplement #MetabolicSyndrome #NAFLD #NASH

Aug 28, 2020 · 1 like · 1 share · 19,467 followers View post →
شيخ الامين الحواريو الدمبلات والبرمجيات
@amin_assaid · X

مصدر: https://t.co/dCRctz0sBr - يقلل من الام الدوره الشهريه: في دراسه اجريه عام 2018 ع العديد من النساء وجدو ان تناول 200iu من فيتامين E يقلل من الام الدوره الشهريه بصوره ملحوظه .. وكانت التاثيرات افضل لما تم دمجه مع omega3. مصدر: https://t.co/NpY591Tt83 - يحسن فيتامين E من

Feb 5, 2023 · 1 like · 614 followers View post →
IberianCitizen
@IberianCitizen · X

RT @nick_krontiris: Systematic review with meta‐analysis: The effect of vitamin E supplementation in adult patients with non‐alcoholic fatt…

Aug 28, 2020 · 1 share · 12,903 followers View post →

All mentions

شيخ الامين الحواريو الدمبلات والبرمجيات
@amin_assaid · X

مصدر: https://t.co/dCRctz0sBr - يقلل من الام الدوره الشهريه: في دراسه اجريه عام 2018 ع العديد من النساء وجدو ان تناول 200iu من فيتامين E يقلل من الام الدوره الشهريه بصوره ملحوظه .. وكانت التاثيرات افضل لما تم دمجه مع omega3. مصدر: https://t.co/NpY591Tt83 - يحسن فيتامين E من

Feb 5, 2023 · 1 like · 614 followers View post →
JeffWill
@J_Real3 · X

https://t.co/5ephN4vkYe

Aug 30, 2022 · 5,064 followers View post →
Fact About Fact
@FactChekPolitic · X

RT @theliverdr: 1 https://t.co/4zYFjQbvOo https://t.co/FCoWT359Zb 2 https://t.co/cCD3reT7Fo 3 https://t.co/MEknkG00vd 4 https://t.co/Kav…

Feb 16, 2022 · 1 share · 461 followers View post →
TheLiverDoc™
@theliverdr · X

1 https://t.co/4zYFjQbvOo https://t.co/FCoWT359Zb 2 https://t.co/cCD3reT7Fo 3 https://t.co/MEknkG00vd 4 https://t.co/Kav0tOeyAL 5 Old study said >/= 400 U per day caused more deaths (2005) https://t.co/bSfe2kQoLk But this was disproven (2014) https://t.co/GL40Wqr9w6

Feb 16, 2022 · 8 likes · 1 share · 314,899 followers View post →
Amarelowbr
@amarelowbr · X

@tallesmrs @jcsouto @lcos3060 @JAMANetworkOpen @JAMANetwork Esse é um resumo do achado publicado na época, conduzido pelo Prof. Geisler, da univ. de Copenhage: https://t.co/cqO3mjdwfa Em relação a vitamina E, talvez ela não seja tão "inutil": https://t.co/hjvuexvnd5, mas esse não é o caso. Abs

May 27, 2021 · 844 followers View post →
Vasile Daniel Balaban
@_vbalaban · X

RT @DrAnuraagJ: Meta-analysis: The effect of vitamin E in patients with NAFLD: Improves biochemical and histological characteristics of NAF…

Apr 10, 2021 · 2 shares · 821 followers View post →
Dr Kaushal Madan
@DrKaushalMadan1 · X

RT @DrAnuraagJ: Meta-analysis: The effect of vitamin E in patients with NAFLD: Improves biochemical and histological characteristics of NAF…

Apr 9, 2021 · 2 shares · 2,291 followers View post →
Anuraag Jena
@DrAnuraagJ · X

Meta-analysis: The effect of vitamin E in patients with NAFLD: Improves biochemical and histological characteristics of NAFLD patients, especially of NASH patients #livertwitter https://t.co/cmvX5epPrq

Apr 9, 2021 · 8 likes · 2 shares · 4,469 followers View post →
IberianCitizen
@IberianCitizen · X

RT @nick_krontiris: Systematic review with meta‐analysis: The effect of vitamin E supplementation in adult patients with non‐alcoholic fatt…

Aug 28, 2020 · 1 share · 12,903 followers View post →
Nick Krontiris
@nick_krontiris · X

Systematic review with meta‐analysis: The effect of vitamin E supplementation in adult patients with non‐alcoholic fatty liver disease https://t.co/CCHDVB3zai #VitaminE #supplements #supplement #MetabolicSyndrome #NAFLD #NASH

Aug 28, 2020 · 1 like · 1 share · 19,467 followers View post →
Prof Julian Barratt RN PhD
@cn150 · X

RT @alephh: Vitamin E vs Liver enzymes in NAFLD (8-study meta-analysis) • ALT ‐7.37 IU/L • AST ‐5.71 IU/L • #VitaminE improved significantl…

Aug 26, 2020 · 2 shares · 3,415 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @alephh: Vitamin E vs Liver enzymes in NAFLD (8-study meta-analysis) • ALT ‐7.37 IU/L • AST ‐5.71 IU/L • #VitaminE improved significantl…

Aug 26, 2020 · 2 shares · 6,703 followers View post →
alephh
@alephh · X

Vitamin E vs Liver enzymes in NAFLD (8-study meta-analysis) • ALT ‐7.37 IU/L • AST ‐5.71 IU/L • #VitaminE improved significantly liver pathology in every individual histologic parameter as well LDL/FBG/leptin values, especially in NASH patients https://t.co/U5oQqz7vdK

Aug 26, 2020 · 3 likes · 2 shares · 388 followers View post →
UpToPhate
@UpToPhate · X

Systematic review with meta-analysis: The effect of vitamin E supplementation in adult patients with non-alcoholic fatty liver disease. https://t.co/iVRCGlxiyV

Aug 21, 2020 · 190 followers View post →