Am J Respir Crit Care Med December 2020 PMID 32813543

On Happy Hypoxia and on Sadly Ignored "Acute Vascular Distress Syndrome" in Patients with COVID-19.

Vincent Jounieaux, Daniel Oscar Rodenstein, Yazine Mahjoub

Download social card

Mentions

20
Peak: 4 in Jan 2021
across 2 sources since Aug 2020

Extended reach

84,231
potential audience

Total likes

229

Video views

33,036

Mentions per month

Aug 2020 – May 2025

Where it's discussed

  • X / Twitter18 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect strong interest, with users referencing detailed physiological explanations such as the role of right-to-left intrapulmonary shunt and diagnostic tools like echocardiograms, indicating moderate engagement. The tone combines technical analysis with acknowledgment of the clinical significance, highlighting the article's impact on understanding COVID-19 hypoxia mechanisms and vascular implications.

AgreementModerate agreement

Most discussions express support or acknowledgment of the article's points, emphasizing the importance of recognizing hypoxia and vascular issues in COVID-19.

InterestHigh interest

The discussions show high interest, with multiple mentions of technical factors, diagnostic methods, and debates surrounding mechanisms.

EngagementModerate engagement

Participants demonstrate moderate engagement, referencing specific concepts like shunts, PFO diagnosis, and the properties of oxygen dissociation.

ImpactModerate impact

The conversations suggest a recognition that the article prompts meaningful clinical and scientific discussions, although broader societal impact seems moderate.

Abstract in brief

  • The article explains the concept of "Happy Hypoxia," a condition where COVID-19 patients have dangerously low oxygen levels but do not show typical signs of distress, leading to delayed medical intervention.
  • It discusses "Acute Vascular Distress Syndrome" (AVDS), highlighting how COVID-19 causes severe blood vessel issues that impair oxygen exchange and contribute to patient deterioration.
  • The text emphasizes the importance of recognizing these hidden symptoms to improve early diagnosis and treatment, which has often been overlooked during the pandemic.]

Top posts

Most liked on X and Bluesky
ニューロドクター乱夢
@hichachu · X

呼吸困難を伴わない低二酸化炭素性低酸素症の理由については、Tobinらが言及しておらず、我々が最も適切な説明をしていると考えているものがある。SARS-CoV-2は、肺の血管増殖を誘発することが知られており、解剖学的研究と放射線学的研究の両方で実証されている(4, 5)。 https://t.co/E0lqJzU7Y6

Jan 8, 2021 · 5 likes · 2 shares · 4,260 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 https://t.co/Z5ZozVu2xC

Feb 3, 2024 · 3 likes · 1 share · 8,769 followers View post →
Rene Sugar
@renesugar · X

https://t.co/R864flDKOA "As to the reasons for hypocapnic hypoxia without dyspnea, there is one that Tobin and colleagues do not mention and that we believe offers the best explanation, as follows: the presence of a right-to-left intrapulmonary shunt"

Oct 8, 2022 · 3 likes · 3,960 followers View post →
Rene Sugar
@renesugar · X

On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with #COVID19 #LongCovid https://t.co/R864flDKOA

Oct 8, 2022 · 3 likes · 1 share · 3,960 followers View post →
Rene Sugar
@renesugar · X

@VladVexler On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 https://t.co/R864flDcZ2 "the presence of a right-to-left intrapulmonary shunt"

May 3, 2025 · 2 likes · 3,960 followers View post →
Welli Bis
@BisWelli · X

@dodi_rains A case of ‘happy’ hypoxia. On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 https://t.co/63Gbt1zJdQ

Sep 6, 2021 · 2 likes · 133 followers View post →

All mentions

Rene Sugar
@renesugar · X

@VladVexler On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 https://t.co/R864flDcZ2 "the presence of a right-to-left intrapulmonary shunt"

May 3, 2025 · 2 likes · 3,960 followers View post →
Bob
@fluxcapdoodah · X

RT @angryhacademic: On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 https://t.co/Z5ZozVu…

Feb 9, 2024 · 1 share · 687 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 https://t.co/Z5ZozVu2xC

Feb 3, 2024 · 3 likes · 1 share · 8,769 followers View post →
Selective Enforcement is ok till it happens to you
@KatherineLutz18 · X

@stkirsch https://t.co/ZFC5q7BbH7 Reaction to Tobin paper: "We would like to advance that the main reason for the phenomenon of happy hypoxia is the presence of hypocapnia..." https://t.co/z0ZvV9BVvh @denisrancourt @HopiNg66966500

Feb 1, 2024 · 397 followers View post →
Selective Enforcement is ok till it happens to you
@KatherineLutz18 · X

@denisrancourt @stkirsch Happy Hypoxia https://t.co/ZFC5q7BbH7 Address Tobin...also discuss definitions & effects of hypoxia, the inaccuracies of pulse saturation, and the properties of the oxygen dissociation curve...

Feb 1, 2024 · 1 like · 397 followers View post →
Rene Sugar
@renesugar · X

@ales_frost @Sam_B_79 @MaryGR65 @ahandvanish https://t.co/TsNHGNnnuN "An echocardiogram can be done to diagnose a PFO. If the PFO is not easily seen, a cardiologist can perform a "bubble test."" https://t.co/JKap8NYumy https://t.co/R864flDKOA "the presence of a right-to-left intrapulmonary shunt"

May 4, 2023 · 1 like · 3,960 followers View post →
Rene Sugar
@renesugar · X

@mrzphd @PutrinoLab @VirusesImmunity @hmkyale @kindred_health @AtelierDanko https://t.co/KeMVzruZGI Ear Oximetry: A Noninvasive Method for Detection of Patent Foramen Ovale https://t.co/JKap8NYumy On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 https://t.co/R864flDKOA https://t.co/mTOVJ5Zwsl

Apr 13, 2023 · 3,960 followers View post →
Rene Sugar
@renesugar · X

https://t.co/R864flDKOA "As to the reasons for hypocapnic hypoxia without dyspnea, there is one that Tobin and colleagues do not mention and that we believe offers the best explanation, as follows: the presence of a right-to-left intrapulmonary shunt"

Oct 8, 2022 · 3 likes · 3,960 followers View post →
Rene Sugar
@renesugar · X

On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with #COVID19 #LongCovid https://t.co/R864flDKOA

Oct 8, 2022 · 3 likes · 1 share · 3,960 followers View post →
Welli Bis
@BisWelli · X

@dodi_rains A case of ‘happy’ hypoxia. On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 https://t.co/63Gbt1zJdQ

Sep 6, 2021 · 2 likes · 133 followers View post →
内田
@uchida_kawasaki · X

RT @hichachu: 呼吸困難を伴わない低二酸化炭素性低酸素症の理由については、Tobinらが言及しておらず、我々が最も適切な説明をしていると考えているものがある。SARS-CoV-2は、肺の血管増殖を誘発することが知られており、解剖学的研究と放射線学的研究の両方で実証さ…

Jan 9, 2021 · 2 shares · 1,928 followers View post →
seki_yo
@seki_yo · X

RT @hichachu: 呼吸困難を伴わない低二酸化炭素性低酸素症の理由については、Tobinらが言及しておらず、我々が最も適切な説明をしていると考えているものがある。SARS-CoV-2は、肺の血管増殖を誘発することが知られており、解剖学的研究と放射線学的研究の両方で実証さ…

Jan 8, 2021 · 2 shares · 1,362 followers View post →
ゆり子
@31icecleamlove9 · X

RT @hichachu: 呼吸困難を伴わない低二酸化炭素性低酸素症の理由については、Tobinらが言及しておらず、我々が最も適切な説明をしていると考えているものがある。SARS-CoV-2は、肺の血管増殖を誘発することが知られており、解剖学的研究と放射線学的研究の両方で実証さ…

Jan 8, 2021 · 2 shares · 101 followers View post →
ニューロドクター乱夢
@hichachu · X

呼吸困難を伴わない低二酸化炭素性低酸素症の理由については、Tobinらが言及しておらず、我々が最も適切な説明をしていると考えているものがある。SARS-CoV-2は、肺の血管増殖を誘発することが知られており、解剖学的研究と放射線学的研究の両方で実証されている(4, 5)。 https://t.co/E0lqJzU7Y6

Jan 8, 2021 · 5 likes · 2 shares · 4,260 followers View post →
Rasoul Aliannejad
@aliannejad · X

On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 | American Journal of Respiratory and Critical Care Medicine https://t.co/2N2SXLE7jc

Dec 27, 2020 · 1 like · 5 followers View post →
@SoMe4MV
@some4mv · X

RT @some4mv: On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 https://t.co/tAWt0rTb0p #SoMe4MV from @ATSBlueEditor

Dec 2, 2020 · 6,328 followers View post →
@SoMe4MV
@some4mv · X

On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in Patients with COVID-19 https://t.co/tAWt0rTb0p #SoMe4MV from @ATSBlueEditor

Dec 1, 2020 · 6,328 followers View post →
Hypoxia Adaptation
@hypoxiapapers · X

On Happy Hypoxia and on Sadly Ignored "Acute Vascular Distress Syndrome" in COVID-19 Patients. https://t.co/8MwfuOZLsP

Aug 21, 2020 · 1 like · 678 followers View post →