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Front Cell Infect Microbiol June 2021 PMID 32850497

Colon Cancer-Associated May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System.

Jawad Abed, Naseem Maalouf, Abigail L Manson, Ashlee M Earl, Lishay Parhi, Johanna E M Emgård, Michael Klutstein, Shay Tayeb, Gideon Almogy, Karine A Atlan, Stella Chaushu, Eran Israeli, Ofer Mandelboim, Wendy S Garrett, Gilad Bachrach

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Mentions

25
Peak: 8 in Aug 2020
across 4 sources since Aug 2020

Extended reach

28,973
potential audience

Total likes

42

Video views

32

Mentions per month

Aug 2020 – Mar 2025

Where it's discussed

  • X / Twitter13 posts
  • News6 articles
  • Blogs4 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions mainly emphasize the significance of bacteria from the mouth reaching the colon via the bloodstream, as shown by phrases like 'highlights the blood route as key' and words like 'excited' and 'important.' The tone and choice of words, such as 'confirmation' and 'more evidence,' reflect recognition of the research's potential to impact understanding of gastrointestinal health and disease pathways.

AgreementModerate agreement

Most discussions recognize the significance of the research linking oral bacteria to colon cancer, indicating a tendency to agree with its implications.

InterestHigh interest

The discussions show high enthusiasm and curiosity about the findings, with many posts emphasizing the novelty and importance of the research.

EngagementHigh engagement

Participants actively discuss the mechanisms, specific bacteria like Fusobacterium nucleatum, and the potential health implications, demonstrating deep engagement.

ImpactModerate impact

While some posts suggest the research could influence future studies or medical approaches, many are still in the early stages of recognizing broad health impacts.

Abstract in brief

  • The study explores the idea that Fusobacteria, a common bacteria found in the mouth, may contribute to the development and progression of colon cancer by traveling from the oral cavity to the colon.
  • Whole genome sequencing of patient samples confirmed that Fusobacteria in colon cancer likely originate from the mouth, and it may reach tumors either through the digestive tract or via the bloodstream, especially during activities like dental procedures.
  • Experiments in mouse models showed that Fusobacteria traveling through the bloodstream (hematogenous route) are more effective at colonizing colon tumors than those introduced directly into the stomach, highlighting the blood route as a key pathway for bacteria to reach colon cancers.
Read the full abstract

Top posts

Most liked on X and Bluesky
Gilad Bachrach Lab
@BachrachLab · X

Excited to share our new paper. @jawad_abed @MaaloufNaseem @FrontCellInfect Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System https://t.co/mqi5U09A62

Aug 7, 2020 · 17 likes · 3 shares · 100 followers View post →
山口幸三 | 腸活研究者
@yguchi53 · X

「歯周病菌が大腸がんの原因になりうる」というのは以前から言われてましたが、その菌はどうも消化管経由ではなく血流経由で口から大腸に移行している可能性が高いかも、、という話。 ある意味、リーキーガットの逆バージョン？ https://t.co/WoMm0AgJLM いずれにしろ歯周病は侮れない。。

Sep 23, 2022 · 14 likes · 2 shares · 228 followers View post →
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@gamonasterioo · X

The oral oncobacterium Fusobacterium nucleatum could colonize colon tumors preferentially using the hematogenous route. More evidence pointing to the key role of the oral cavity in gastrointestinal diseases! Beautiful work of @BachrachLab #OralGutAxis https://t.co/VfjQilCDjP

Aug 7, 2020 · 4 likes · 1 share · 1,662 followers View post →
Alexander Link
@alinkmd · X

Colon #Cancer-Associated #Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System confirmation of the previous data using in vitro model! https://t.co/BnaWXkRk5I

Aug 29, 2020 · 4 likes · 1 share · 1,439 followers View post →
Frontiers - Infectious Disease
@FrontInfectDis · X

Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System https://t.co/fE1Ye6NpNB #cellinfect

Aug 8, 2020 · 2 likes · 1 share · 3,833 followers View post →
大武ユキ@フットボールネーション19巻
@YUKI_OTAKE · X

RT @yguchi53: 「歯周病菌が大腸がんの原因になりうる」というのは以前から言われてましたが、その菌はどうも消化管経由ではなく血流経由で口から大腸に移行している可能性が高いかも、、という話。 ある意味、リーキーガットの逆バージョン？ https://t.co/WoM…

Sep 23, 2022 · 2 shares · 10,969 followers View post →

All mentions

ゆっきー@11/16東6 ル62a
@yukiqlair · X

RT @yguchi53: 「歯周病菌が大腸がんの原因になりうる」というのは以前から言われてましたが、その菌はどうも消化管経由ではなく血流経由で口から大腸に移行している可能性が高いかも、、という話。 ある意味、リーキーガットの逆バージョン？ https://t.co/WoM…

Sep 23, 2022 · 2 shares · 325 followers View post →
大武ユキ@フットボールネーション19巻
@YUKI_OTAKE · X

RT @yguchi53: 「歯周病菌が大腸がんの原因になりうる」というのは以前から言われてましたが、その菌はどうも消化管経由ではなく血流経由で口から大腸に移行している可能性が高いかも、、という話。 ある意味、リーキーガットの逆バージョン？ https://t.co/WoM…

Sep 23, 2022 · 2 shares · 10,969 followers View post →
タケ ダイグウジ@アスレティックパフォーマンスコーチ
@takedaiguji · X

RT @yguchi53: 「歯周病菌が大腸がんの原因になりうる」というのは以前から言われてましたが、その菌はどうも消化管経由ではなく血流経由で口から大腸に移行している可能性が高いかも、、という話。 ある意味、リーキーガットの逆バージョン？ https://t.co/WoM…

Sep 23, 2022 · 2 shares · 5,113 followers View post →
山口幸三 | 腸活研究者
@yguchi53 · X

「歯周病菌が大腸がんの原因になりうる」というのは以前から言われてましたが、その菌はどうも消化管経由ではなく血流経由で口から大腸に移行している可能性が高いかも、、という話。 ある意味、リーキーガットの逆バージョン？ https://t.co/WoMm0AgJLM いずれにしろ歯周病は侮れない。。

Sep 23, 2022 · 14 likes · 2 shares · 228 followers View post →
CryptoBiome
@Cryptobiome22 · X

Do you know bad #bacteria in your #mouth can cause #colon #cancer? https://t.co/DMOcRoYHnD

Jan 12, 2022 · 6 followers View post →
Michael P. Owen
@owenmp · X

RT @alinkmd: Colon #Cancer-Associated #Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulator…

Aug 30, 2020 · 1 share · 1,124 followers View post →
Alexander Link
@alinkmd · X

Colon #Cancer-Associated #Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System confirmation of the previous data using in vitro model! https://t.co/BnaWXkRk5I

Aug 29, 2020 · 4 likes · 1 share · 1,439 followers View post →
Frontiers - Infectious Disease
@FrontInfectDis · X

Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System https://t.co/fE1Ye6NpNB #cellinfect

Aug 8, 2020 · 2 likes · 1 share · 3,833 followers View post →
Gilad Bachrach Lab
@BachrachLab · X

RT @gamonasterioo: The oral oncobacterium Fusobacterium nucleatum could colonize colon tumors preferentially using the hematogenous route.…

Aug 8, 2020 · 1 share · 100 followers View post →
.
@gamonasterioo · X

The oral oncobacterium Fusobacterium nucleatum could colonize colon tumors preferentially using the hematogenous route. More evidence pointing to the key role of the oral cavity in gastrointestinal diseases! Beautiful work of @BachrachLab #OralGutAxis https://t.co/VfjQilCDjP

Aug 7, 2020 · 4 likes · 1 share · 1,662 followers View post →
Frontiers - Infectious Disease
@FrontInfectDis · X

RT @BachrachLab: Excited to share our new paper. @jawad_abed @MaaloufNaseem @FrontCellInfect Colon Cancer-Associated Fusobacterium nuclea…

Aug 7, 2020 · 3 shares · 3,833 followers View post →
The Institute of Biomedical and Oral Research
@InstituteofDen1 · X

RT @BachrachLab: Excited to share our new paper. @jawad_abed @MaaloufNaseem @FrontCellInfect Colon Cancer-Associated Fusobacterium nuclea…

Aug 7, 2020 · 3 shares · 166 followers View post →
Gilad Bachrach Lab
@BachrachLab · X

Excited to share our new paper. @jawad_abed @MaaloufNaseem @FrontCellInfect Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System https://t.co/mqi5U09A62

Aug 7, 2020 · 17 likes · 3 shares · 100 followers View post →