@nelsonepega Receipts- LINE1 expression is not limited to Cancer cell lines. https://t.co/gNuLV8rIQu https://t.co/1DmhlJwfH2
New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation.
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Aug 2020 – Sep 2025Where it's discussed
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X / Twitter99 posts
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YouTube4 videos
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Facebook2 posts
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News2 articles
AI synopsis
What people are saying
Discussions highlight various aspects of LINE-1 retrotransposition, with many users referencing prior studies, such as Piskareva2011 and Dunaeva2018, which link elevated L1 levels to tumorigenesis. The tone reflects concern and curiosity, with phrases like 'not enough work is needed' and mentions of 'urgent testing' illustrating the urgency and importance users place on this research.
Most discussions express general support for the findings of the article, though there are some disagreements about specific implications.
There is a strong interest in the topic, with many users actively engaging with the research and discussing its relevance.
While some posts indicate a lack of deep engagement, many users are asking questions and referencing prior studies, which shows moderate engagement.
Many users believe that the findings of the article have significant implications for understanding human diseases and vaccine effects.
Abstract in brief
- LINE1 retrotransposition is linked to cancer, contributing to genetic instability and poor disease outcomes.
- LINE1 also influences the immune system by triggering innate immune responses, potentially leading to autoimmunity and inflammation.
- Inhibiting LINE1 activity presents a promising treatment approach for a range of diseases, as explored in this review.
Top posts
Most liked on X and Bluesky@AngryCardio Aberrant LINE-1 (endogenous reverse transcriptase) expression is all over the literature as studied for cancer, neutrological, and autoimmune association. https://t.co/sHIIFXtUaq
癌はspike mRNAのRetrotranscription⬆️? 疾患・免疫:LINE-1 Retrotransposition https://t.co/aTs4qhcHWf CpG islandのmethyl化伴うepigenetic修飾⇨遺伝子発現制御 LINE-1のmethyl化程度はDNA methyl化代用 LINE-1活性は乳癌、食道癌、結腸癌、肺扁平上皮癌等と関連 腫瘍抑制遺伝子⬇️⇨増殖浸潤⬆️ https://t.co/Z9E0awOzav
@Parsifaler The scary thing is that LINE-1 by itself can induce cancer and other diseases by DNA hypomethylation https://t.co/lnQ4DndgBX We urgently need to begin testing to see for how long LINE-1 remains elevated
@AngryCardio LINE-1 expression is in both the virus and the vaccine showing the role of the Spike Protein. If children can clear the virus through innate/strong t-cell reactions, then it would be preferrable NOT to inject them with a LINE-1 stimulant-long term view. https://t.co/r6juxIbbUX
@Debunk_the_Funk @ale_battini @JonathanSarfat1 @villagerssn @GirardotMarc @FactsThen Funk Fabrications are only 1 google away of debunking. It’s active in metabolic disease. The very people prioritized for the vax. Debunker is always dead wrong. https://t.co/PDCnxamROP https://t.co/fglnP6JjXq
All mentions
วัคซีนไฟเซอร์และไวรัสโควิดเข้าไปเป็นส่วนนึงของ DNA คนได้ ทีนี้จะทำยังไงดี อธิบายลงลึก (ยากนะครับ)
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Impact of Pfizer Vaccine mRNA on DNA in Liver Cells Explained
This video summarizes findings from a Swedish study showing how the Pfizer BioNTech vaccine may transform into DNA within liver cells. Key insights include the elevation of LINE1 protein in response to the vaccine…
@InfinityHealth8 @TheABFM Refresher is in order for them https://t.co/bjH4CL90Mr
@NicHulscher since elevated L1 level is correlated with tumorigenesis (tumor cell proliferation) as shown by Piskareva2011 (https://t.co/KWKGsLRoYp), Dunaeva2018 (https://t.co/e7vfoCv2ht), Zhang2020 (https://t.co/cTAXjPqDVy)
@lovesounds777 @healthyskeptic_ @VaccineMole Long INterspersed Element (LINE) 1 or 2 ? https://t.co/HK1jfvxKGe
RT @Clucky92864053: 7) Not enough - much more work is needed because we are concerned about incorporation of mRNA into the human genome. I…
@sjs856 @jeffdornik What are you talking about? It’s recently been shown mRNA can form facultative heterochromatin in inactive L1s and form RISC degradation—You think synthetic mRNA doesn’t matter? Disgusting assumption. https://t.co/8qQwA0NRof https://t.co/8qQwA0NRof https://t.co/3v6UObkphB
https://t.co/IuoIHcczPQ LINE-1(L1) mRNAは細胞質に輸出,ORF1とORF2翻訳,結合,リボ核蛋白(RNP)形成 RNPは核に組み込み,RNP内ORF2P endonucleaseがconsensus site3′-′AA/TTTT−5′で下側DNA鎖の特定配列を切断 →生成の遊離3′hydroxylはORF2Pで利用,RNP内L1 mRNAは逆転写template使用,L1
@P_McCulloughMD @MakisMD @McKinneyFMTX @MdBreathe @MelissaProcter8 @DrNoMask @drcraigwax @drscottjensen @CartlandDavid @VigilantFox @VigilantNews @TheChiefNerd Numerous articles noted that Line-1 was activated by the Covid vax. Line-1 is notorious for retrotransposition. Oncology papers recommend deactivating this gene. This also explains the rise in autoimmune diseases. https://t.co/E6HJUEO7A3
@VigilantFox @VigilantNews @CircDNA since elevated L1 level is correlated with tumorigenesis (tumor cell proliferation) as shown by Piskareva2011 (https://t.co/KWKGsLRoYp), Dunaeva2018 (https://t.co/e7vfoCv2ht), Zhang2020 (https://t.co/cTAXjPqDVy)
@TheChiefNerd @CircDNA since elevated L1 level is correlated with tumorigenesis (tumor cell proliferation) as shown by Piskareva2011 (https://t.co/KWKGsLRoYp), Dunaeva2018 (https://t.co/e7vfoCv2ht), Zhang2020 (https://t.co/cTAXjPqDVy)
@VigilantFox @CircDNA since elevated L1 level is correlated with tumorigenesis (tumor cell proliferation) as shown by Piskareva2011 (https://t.co/KWKGsLRoYp), Dunaeva2018 (https://t.co/e7vfoCv2ht), Zhang2020 (https://t.co/cTAXjPqDVy)
@_ppmv @inkblue01 Not sure exactly what I am misreading. https://t.co/u0alvXy91s https://t.co/cGWBnP0cpU
@inkblue01 @CovidSolidarit1 One way for SARS 2 to integrate into the genome and replicate is through LINE-1…like HIV. https://t.co/cGWBnP0cpU
@allangmiller1 @BenSmit81581660 @ColinDebunks "LINE-1 is *RNA specific*. Not DNA" https://t.co/QTTUGTVssy Long interspersed nuclear elements (LINEs)... LINE-1 retrotransposons are one of the most abundant and effective classes of mobile DNAs that account for 17% of the human genome (Lander et al., 2001; Hancks and Kazazian
@Madeyoul0o0k @Fan2La88 @JasonHoltzman71 @Timcast I'm taking you through the steps, since you're in denial. You're putting your trust in Pfizer the most heavily sued corporation due to harmful drugs they have introduced. https://t.co/4L7BzpcX9L
@stkirsch since elevated L1 level is correlated with tumorigenesis (tumor cell proliferation) as shown by Piskareva2011 (https://t.co/KWKGsLRoYp), Dunaeva2018 (https://t.co/e7vfoCv2ht), Zhang2020 (https://t.co/cTAXjPqDVy)
@Fynnderella1 since elevated L1 level is correlated with tumorigenesis (tumor cell proliferation) as shown by Piskareva2011 (https://t.co/KWKGsLRoYp), Dunaeva2018 (https://t.co/e7vfoCv2ht), Zhang2020 (https://t.co/cTAXjPqDVy)
@tonymac5 @TigerlillySusan @jonathanstea @Inquiry_Canada The fact the Line-1 You speak of is present in all Human Beings is quite alarming. New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation https://t.co/jPA62rZKIo
@Kevin_McKernan since elevated L1 level is correlated with tumorigenesis (tumor cell proliferation) as shown by Piskareva2011 (https://t.co/KWKGsLRoYp), Dunaeva2018 (https://t.co/e7vfoCv2ht), Zhang2020 (https://t.co/cTAXjPqDVy)
@NarfGb @tatiann69922625 @AnneliseBocquet @DoorlessCarp @Jikkyleaks @Kevin_McKernan @kacdnp91 @Maples46014332 @Fynnderella1 @c0v1d1984 @RetsefL @sasha_latypova @shmuelcshapira @PinsolleT @FluoridePoison @joshg99 @JCPEREZCODEX @deNutrients @knigotnik @SAW_BW @ClareCraigPath @chefofmembers @GauteNilsen @ARadlerPohlDr @NestCommander @nycliusa Currently plowing thru the paper https://t.co/rPS84yOalb
3.modRNAはヒト
@cyndymcfarland @MsPinkest1968 @DocAhmadMalik Here you go: https://t.co/qtfI0zmSau. That'll make it clear why cancer cells in dishes are a research tool, but not real predictive of what will happen in the body. Isolated liver cells also don't have an immune system, by definition.
@MEUNIERPatric11 @SaiyanBio @cvrx Tu ne sais pas de quoi tu parles line prend pas n importe quel ARN. C'est son propre ARNm au lieu de dire de la merde au moins apprenez le mécanisme. De plus il ne s intègre dans des régions specifique de l'ADN par un mécanisme particulier. https://t.co/kJdJuZl1o6
RT @0bj3ctivity: "New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation" https://t.co…
"New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation" https://t.co/vJpFILPrm8
@ejustin46 @fitterhappierAJ @HarrySpoelstra @DavidJoffe64 @mrmickme @C_A_Gustave @arijitchakrav @DavidJoffe64 @0bj3ctivity LINE-1 and carcinogenesis https://t.co/4rhXwiS0bQ.
@wanderer_jasnah https://t.co/bjH4CL90Mr
@TRyanGregory Ok...well I learned something new and well, crap https://t.co/IKDJtwFdH9
Frontiers | New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation https://t.co/AdhwvfPGa1
RT @Kevin_McKernan: @nelsonepega Receipts- LINE1 expression is not limited to Cancer cell lines. https://t.co/gNuLV8rIQu https://t.co/1Dmh…
@nelsonepega Receipts- LINE1 expression is not limited to Cancer cell lines. https://t.co/gNuLV8rIQu https://t.co/1DmhlJwfH2
@nelsonepega New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation https://t.co/Dv76LS3Q76
@RWMaloneMD
@Lego_Scientist @BreezerGalway @Telegraph Assuming the ”vaccine” does not include a reverse transcriptase (as they claim it would not contain), there are natural origin of such function. No other virus needed. https://t.co/r6OOfqK1lB
@healthbyjames
@P_McCulloughMD
@LonelyChell79 @HetLaffePaars @BadMedicalTakes @AmyPertri Jury isn't quite out on that one. C19 vax could induce LINE-1 expression -- something that is wildly concerning for a number of reasons. https://t.co/2yc1VKbkYp https://t.co/NbcNUQemgS https://t.co/q364hxQVle
癌はspike mRNAのRetrotranscription⬆️? 疾患・免疫:LINE-1 Retrotransposition https://t.co/aTs4qhcHWf CpG islandのmethyl化伴うepigenetic修飾⇨遺伝子発現制御 LINE-1のmethyl化程度はDNA methyl化代用 LINE-1活性は乳癌、食道癌、結腸癌、肺扁平上皮癌等と関連 腫瘍抑制遺伝子⬇️⇨増殖浸潤⬆️ https://t.co/Z9E0awOzav
@LeftwardSwing @themattdimitri This study says WE DON'T KNOW but it does change 2 DNa N the Liver. So this one indicates a need 4 MORE Studies! https://t.co/1yWzpVLm21
RT @Steve42381050: Pfizer vaccine becomes DNA in liver | Does Pfizer mRNA it integrates wit... https://t.co/7bsOYyx8Xw via @YouTube
Pfizer vaccine becomes DNA in liver | Does Pfizer mRNA it integrates wit... https://t.co/7bsOYyx8Xw via @YouTube
@RyvesWilliam @sophiefloating This should help you ☺️ https://t.co/QzpqcDlrXZ
11/15 After Y. Miki, et al., (1992) showed L1's involvement in #Cancer, new studies were conducted which deduced that hypomethylation of L1 served as a biomarker in #GastricCancer, #LungCancer, #LiverCancer, #EsophagealCancer, #ProstateCancer, etc... https://t.co/ReiVPrtjAQ
@Chris_F_Carson @GreyTonka @NikolovScience https://t.co/jtPD3FuzF0
RT @Kevin_McKernan: @Debunk_the_Funk @ale_battini @JonathanSarfat1 @villagerssn @GirardotMarc @FactsThen Funk Fabrications are only 1 googl…
RT @Kevin_McKernan: @Debunk_the_Funk @ale_battini @JonathanSarfat1 @villagerssn @GirardotMarc @FactsThen Funk Fabrications are only 1 googl…
@Debunk_the_Funk @ale_battini @JonathanSarfat1 @villagerssn @GirardotMarc @FactsThen Funk Fabrications are only 1 google away of debunking. It’s active in metabolic disease. The very people prioritized for the vax. Debunker is always dead wrong. https://t.co/PDCnxamROP https://t.co/fglnP6JjXq
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
#โควิด น่าสนใจ หุหุ เขาว่า เชื้อไวรัส กะ #mRNA สามารถเข้าไปใน DNA เช่น เซลล์ตับของคนได้ (แต่ยังเป็นแค่การทดลอง) https://t.co/0VdVAMSpCl #ห้องส่องทางไกล
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
https://t.co/5Z7AGYTGFy
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: 7) Not enough - much more work is needed because we are concerned about incorporation of mRNA into the human genome. I…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
@Parsifaler The scary thing is that LINE-1 by itself can induce cancer and other diseases by DNA hypomethylation https://t.co/lnQ4DndgBX We urgently need to begin testing to see for how long LINE-1 remains elevated
@AmaranDeloj @Genesis1063 @AfpFactuel bien rouillé! pas pour nous traiter de "stupide". Bien feignant aussi pour ne pas aller vérifier avant de parler. Les LINE sont des rétrotransposons autonomes et actifs. donc ils donnent aux cellules les capacités de rétrotranscription et d'intégration. https://t.co/zbYlbTCVDO
RT @Clucky92864053: @AngryCardio Aberrant LINE-1 (endogenous reverse transcriptase) expression is all over the literature as studied for ca…
RT @Clucky92864053: @AngryCardio LINE-1 expression is in both the virus and the vaccine showing the role of the Spike Protein. If children…
@AngryCardio LINE-1 expression is in both the virus and the vaccine showing the role of the Spike Protein. If children can clear the virus through innate/strong t-cell reactions, then it would be preferrable NOT to inject them with a LINE-1 stimulant-long term view. https://t.co/r6juxIbbUX
@AngryCardio Aberrant LINE-1 (endogenous reverse transcriptase) expression is all over the literature as studied for cancer, neutrological, and autoimmune association. https://t.co/sHIIFXtUaq
RT @lulu_bee17: @ScienceVickers @desmoncrayz @TransSplendor Ok fine. Here’s a start for you… read this. And then we will talk about why the…
@ScienceVickers @desmoncrayz @TransSplendor Ok fine. Here’s a start for you… read this. And then we will talk about why these matter https://t.co/GS7qxdCLih
วัคซีนไฟเซอร์และไวรัสโควิดเข้าไปเป็นส่วนนึงของ DNA คนได้ ทีนี้จะทำยังไงด... https://t.co/8VPd5tutnq // หลังจากบ่นว่าเจอคนคุยไม่รู้เรื่องเยอะมากวันนี้ เลยมาดูคลิปคุณหมอเลขเชอรี่เสิช เราก็ได้กลายเป็นคนฟังไม่รู้เรื่องแล้ว บาลานชีวิตดีเว่อ
@balkraix https://t.co/AQIC27G9bp
เห็นหมอต่างชาติพูดมาตั้งแต่เปเปอร์ตีพิมพ์แรกๆ รู้แหละว่ายังไงก็ฉีดวัคซีนดีกว่าไม่ฉีด แต่บ้านเราคือเงียบมากนะ https://t.co/bIgM1T7xOG
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
@tasinasie @DrHegedues Genau die; mit Krebszellen, in denen LINE-1, im Vergleich zu gesunden Zellen, anormal hoch aktiv ist. https://t.co/SwmwvVOKxY https://t.co/syrMqAQjV6
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
https://t.co/JYfaiXk1xe
https://t.co/1MbDGZq6F7
วัคซีนไฟเซอร์และไวรัสโควิดเข้าไปเป็นส่วนนึงของ DNA คนได้ ทีนี้จะทำยังไงด... https://t.co/lXk890IOR8 via @YouTube
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
@kgreene90 @i3_lake @jlazewatsky @art_PrintStudio @MartinKulldorff It’s in the release of @pfizer documents. Then there’s this https://t.co/pnJ9xhSuv9 then you can go read this https://t.co/rtT58H86qa to understand the potential issues and ZERO long term studies.
@jlazewatsky @i3_lake @art_PrintStudio @kgreene90 @MartinKulldorff It’s in the release of @pfizer documents. Then there’s this https://t.co/UcynKvKbRj then you can go read this https://t.co/BwUAkwf9yS to understand the potential issues and ZERO long term studies.
@LucasFultz @Leighincognito @Orwells_Ghost_ Your condescending attitude thinking people couldn’t understand lacks in manners and class. Line 1 uptake has been associated with disease occurrence as per this study https://t.co/BwUAkwf9yS. Regardless, the fact vaccines ARE interacting and no long term studies = worrisome
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: 7) Not enough - much more work is needed because we are concerned about incorporation of mRNA into the human genome. I…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
RT @Clucky92864053: @JikkyKjj @GenEntanglement @tony_vandongen @Kevin_McKernan I hope everyone will not miss that we found out something ve…
New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation: https://t.co/Zy0i0NFBfS
New Research: New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation: Long interspersed nuclear element-1 (LINE-1) retrotransposition is a major hallmark of cancer accompanied by global… https://t.co/anBVK8QZ7y #celldevbio