PubHawk
J Am Coll Cardiol September 2020 PMID 32854843

Pulsed Field Ablation for Persistent Atrial Fibrillation (PersAFOne): Hope or Hype?

David R Tomlinson, John Mandrola

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Mentions

15
Peak: 6 in Aug 2020
across 3 sources since Aug 2020

Extended reach

243,468
potential audience

Total likes

35

Video views

83

Mentions per month

Aug 2020 – May 2025

Where it's discussed

  • X / Twitter11 posts
  • Bluesky2 posts
  • YouTube2 videos

AI synopsis

What people are saying

The strong interest and engagement are evidenced by posts praising PFA's high success rates and patient outcomes, like '99.7% procedural success,' while also debating safety concerns, such as brain white matter lesions. The tone shifts from optimistic to cautious, illustrating how the discussions are balancing hope with critical analysis of safety and long-term effects.

AgreementModerate agreement

Most discussions recognize the promising results of PFA, especially noting its high success rate and potential benefits, though some express caution about safety concerns.

InterestHigh interest

The conversations demonstrate high curiosity, especially around clinical outcomes and safety issues, indicating strong engagement with the topic.

EngagementModerate engagement

Participants reference specific studies, clinical outcomes, and safety issues, showing they are actively analyzing and debating the findings.

ImpactModerate impact

The discussions suggest the article has a meaningful influence, prompting further dialogue about PFA’s safety, effectiveness, and future potential.

Abstract in brief

  • The document discusses Pulsed Field Ablation (PFA) as a new treatment for persistent atrial fibrillation (PersAF), emphasizing its potential advantages over traditional methods like thermal ablation, such as being quicker and more tissue-selective.
  • It reviews current research and clinical trials, highlighting both promising results in terms of safety and efficacy, and the need for further studies to confirm PFA's long-term benefits and optimal application techniques.
  • The text balances optimism about PFA's potential with caution, suggesting that while it offers hope for better management of PersAF, more evidence is needed before it can become a standard treatment.]
Read the full abstract

Top posts

Most liked on X and Bluesky
David R Tomlinson
@DRTomlinsonEP · X

@drjohnm @HH4EHRA @jskoruth Thank you from me too and yes, I agree with John! Direct link to editorial here: looking forward to hearing what others think.

Aug 25, 2020 · 12 likes · 3 shares · 8,106 followers View post →
STITCHES Medicine - the Best of Medical Research
@medicine.stitches.today · Bluesky

Pulsed Field Ablation for persistent atrial fibrillation achieved 99.7% procedural success and 85.3% patient freedom from symptoms after one year. by Reddy VY, Gerstenfeld EP (...) Mansour M et 31 al. in J Am Coll Cardiol #MedSky

May 14, 2025 · 8 likes · 1 share View post →
John Mandrola, MD
@drjohnm · X

Two authors worried about this issue 3 years ago in the pages of JACC https://t.co/avhukw9uoG cc @DRTomlinsonEP https://t.co/dCZU3BCpTa

Dec 10, 2023 · 7 likes · 2 shares · 68,978 followers View post →
John Mandrola, MD
@drjohnm · X

PFA has great potential, but we must be careful about its safety--especially in the brain As it were @DRTomlinsonEP and I have opined on this issue/ https://t.co/BzZgn8RYdr #WAFib2021 https://t.co/cU85va2D5L https://t.co/BF40JSCiFd

Feb 27, 2021 · 6 likes · 68,978 followers View post →
David R Tomlinson
@DRTomlinsonEP · X

@DrAJRestrepo @KashifMD @LuigiDiBiaseMD @EuropaceEiC @GiulioConte9 @Dominik_Linz @AndyZhangMD @marcovitoloMD @MBergonti @FraSantoroMD @drjohnm @atulverma_md @mcfinlay Fully covered here, along with @drjohnm Most troubling, was the fact that these investigators set themselves the task of validating the extent of brain white matter lesions with CMR, & then performed precisely zero scans in the very next study Why? https://t.co/YZUgrS1MH1

Jan 18, 2024 · 1 like · 8,106 followers View post →
Nixa Sedes, MD
@nixassedes.bsky.social · Bluesky

Pulsed Field Ablation for Persistent Atrial Fibrillation: 1-Year Results of ADVANTAGE AF

Apr 28, 2025 · 1 like View post →

All mentions

STITCHES Medicine - the Best of Medical Research
@medicine.stitches.today · Bluesky

Pulsed Field Ablation for persistent atrial fibrillation achieved 99.7% procedural success and 85.3% patient freedom from symptoms after one year. by Reddy VY, Gerstenfeld EP (...) Mansour M et 31 al. in J Am Coll Cardiol #MedSky

May 14, 2025 · 8 likes · 1 share View post →
Nixa Sedes, MD
@nixassedes.bsky.social · Bluesky

Pulsed Field Ablation for Persistent Atrial Fibrillation: 1-Year Results of ADVANTAGE AF

Apr 28, 2025 · 1 like View post →
David R Tomlinson
@DRTomlinsonEP · X

@DrAJRestrepo @KashifMD @LuigiDiBiaseMD @EuropaceEiC @GiulioConte9 @Dominik_Linz @AndyZhangMD @marcovitoloMD @MBergonti @FraSantoroMD @drjohnm @atulverma_md @mcfinlay Fully covered here, along with @drjohnm Most troubling, was the fact that these investigators set themselves the task of validating the extent of brain white matter lesions with CMR, & then performed precisely zero scans in the very next study Why? https://t.co/YZUgrS1MH1

Jan 18, 2024 · 1 like · 8,106 followers View post →
bujaj49
@bujaj49 · X

RT @drjohnm: Two authors worried about this issue 3 years ago in the pages of JACC https://t.co/avhukw9uoG cc @DRTomlinsonEP

Dec 10, 2023 · 2 shares · 1,035 followers View post →
David R Tomlinson
@DRTomlinsonEP · X

RT @drjohnm: Two authors worried about this issue 3 years ago in the pages of JACC https://t.co/avhukw9uoG cc @DRTomlinsonEP

Dec 10, 2023 · 2 shares · 8,106 followers View post →
John Mandrola, MD
@drjohnm · X

Two authors worried about this issue 3 years ago in the pages of JACC https://t.co/avhukw9uoG cc @DRTomlinsonEP https://t.co/dCZU3BCpTa

Dec 10, 2023 · 7 likes · 2 shares · 68,978 followers View post →
John Mandrola, MD
@drjohnm · X

PFA has great potential, but we must be careful about its safety--especially in the brain As it were @DRTomlinsonEP and I have opined on this issue/ https://t.co/BzZgn8RYdr #WAFib2021 https://t.co/cU85va2D5L https://t.co/BF40JSCiFd

Feb 27, 2021 · 6 likes · 68,978 followers View post →
Tolga Aksu, MD
@MDTolgaAksu · X

RT @DRTomlinsonEP: @drjohnm @HH4EHRA @jskoruth Thank you from me too and yes, I agree with John! Direct link to editorial here: looking for…

Aug 25, 2020 · 3 shares · 8,458 followers View post →
Till Althoff
@TillAlthoff · X

RT @DRTomlinsonEP: @drjohnm @HH4EHRA @jskoruth Thank you from me too and yes, I agree with John! Direct link to editorial here: looking for…

Aug 25, 2020 · 3 shares · 808 followers View post →
John Mandrola, MD
@drjohnm · X

RT @DRTomlinsonEP: @drjohnm @HH4EHRA @jskoruth Thank you from me too and yes, I agree with John! Direct link to editorial here: looking for…

Aug 25, 2020 · 3 shares · 68,978 followers View post →
David R Tomlinson
@DRTomlinsonEP · X

@drjohnm @HH4EHRA @jskoruth Thank you from me too and yes, I agree with John! Direct link to editorial here: looking forward to hearing what others think.

Aug 25, 2020 · 12 likes · 3 shares · 8,106 followers View post →
Dataemia
@Dataemia · X

Pulsed Field Ablation for Persistent Atrial Fibrillation (PersAFOne): Hope or Hype? - https://t.co/AwsZHeX5B5 https://t.co/JZ9QSQt2XW

Aug 24, 2020 · 963 followers View post →
INDoximity
@indoximity · X

Pulsed Field Ablation for Persistent Atrial Fibrillation (PersAFOne): Hope or Hype? https://t.co/8umyFkIVIp #Cardiology #JACC

Aug 24, 2020 · 832 followers View post →