Cell Metab October 2020 PMID 32905798

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle.

Christine S Kim, Xiaolei Ding, Kira Allmeroth, Leah C Biggs, Olivia I Kolenc, Nina L'Hoest, Carlos Andrés Chacón-Martínez, Christian Edlich-Muth, Patrick Giavalisco, Kyle P Quinn, Martin S Denzel, Sabine A Eming, Sara A Wickström

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Mentions

Peak: 19 in Sep 2020

across 4 sources since Sep 2020

Extended reach

192,911

potential audience

Total likes

544

Video views

20,945

Mentions per month

Sep 2020 – Jun 2023

Where it's discussed

X / Twitter36 posts
News20 articles
Blogs3 articles
YouTube2 videos

AI synopsis

What people are saying

The discussions reflect high agreement and interest, with many posts emphasizing the innovative nature of the findings and their potential to influence treatments for hair loss, evidenced by phrases like 'super cool work!!!' and mentions of the metabolic mechanisms involved, showing both enthusiasm and recognition of its importance.

AgreementStrong agreement

Most discussions endorse the significance of the research, with comments highlighting the importance of metabolic regulation in stem cell fate and hair regeneration.

InterestHigh interest

Posts express high curiosity and enthusiasm, emphasizing the innovative aspects and potential applications of the study.

EngagementModerate engagement

There is active engagement with references to mechanisms, such as mTORC2 signaling, and expressions of excitement like 'super cool work!!!', indicating meaningful interest though some comments are simple acknowledgments.

ImpactHigh impact

Multiple posts suggest the research could have significant implications for understanding hair loss and regenerative medicine, framing it as impactful for future therapies.

Abstract in brief

The study explores how hair follicle stem cells (HFSCs) can switch back to their original stem cell state after activation, which is essential for hair follicle regeneration, and finds that this process depends on controlling their metabolism, specifically the suppression of a switch from glycolysis to glutamine-driven oxidative phosphorylation.
The mammalian target of rapamycin complex 2 (mTORC2) and Akt signaling within the niche regulate this metabolic switch and the reversibility of HFSC fate; disruption of mTORC2 impairs the ability of cells to return to the stem cell state, leading to defective hair regeneration.
These results emphasize the crucial role of precise spatial and temporal regulation of stem cell metabolism in maintaining organ function and tissue homeostasis over the long term.]

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Hair Follicle Stem Cell Metabolism and Regeneration Mechanisms

This video discusses how hair follicle stem cells switch back to their original state, which is crucial for hair regeneration. It highlights the role of controlling cell metabolism, especially the suppression of…

Haircafe · Jun 15, 2023 20,868 views

Role of Glutamine Metabolism in Hair Follicle Stem Cell Maintenance

This video explores how hair follicle stem cells can revert to their original state, crucial for regeneration, by regulating their metabolism, particularly glutamine-driven oxidative phosphorylation and its control by…

Doppelganger Biosystem GmbH · Jan 11, 2023 77 views

bloodybricks

@bloodybricks · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Jan 4, 2023 · 8 shares · 338 followers View post →

Kursad Turksen

@kursadturksen · X

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co/aLyJeV1hU1

Nov 14, 2021 · 231 followers View post →

RRID Robot

@RobotRrid · X

RRIDs were included in the Cell Metabolism paper "Glutamine Metabolism Controls Stem Cell Fate Rever…" (https://t.co/OaO5IWRflX). RRIDs like this improve reproducibility in scientific research. #methodsmatter #STMpublishing

Apr 30, 2021 · 161 followers View post →

Kursad Turksen

@kursadturksen · X

#STEMCELL #WICKSTROM_LAB Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co/aLyJeViSLz

Apr 19, 2021 · 231 followers View post →

Miguel Ángel Sogorb

@MASogorb · X

Mecanismo innovador que previene la caída del cabello https://t.co/oPPsrScbzw Más información: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co/3l0ioR3qQS

Oct 24, 2020 · 158 followers View post →

Marouan Zarrouk, Ph.D.

@Marozar82 · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Oct 9, 2020 · 9 shares · 195 followers View post →

S Rodriguez-Cuenca

@mynameiscormac · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Oct 9, 2020 · 9 shares · 498 followers View post →

Kira Allmeroth

@kira_allmeroth · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Oct 9, 2020 · 9 shares · 171 followers View post →

Backialakshmi Dharmalingam

@Dhapubavi · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Oct 9, 2020 · 9 shares · 241 followers View post →

Bruna Martins Garcia

@BrunaMartinsGa2 · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Oct 9, 2020 · 9 shares · 1,191 followers View post →

Wickstrom-Lab

@WickstromLab · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Oct 9, 2020 · 9 shares · 3,726 followers View post →

Mimi_ Cardio

@mimi_cardio · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Oct 8, 2020 · 9 shares · 188 followers View post →

Terumi WASHIO

@meme_ysr · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Oct 8, 2020 · 9 shares · 122 followers View post →

Alexis Lomakin, Ph.D. (אל) אַלעקסיס לאָמאַקין

@Alexis_Lomakin · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Oct 8, 2020 · 9 shares · 3,643 followers View post →

Cell Metabolism

@Cell_Metabolism · X

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co/zIZpjVVnUP

Oct 8, 2020 · 25 likes · 9 shares · 53,672 followers View post →

STEM CELLS@LIFE

@STEMCELLSLIFE1 · X

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle: Cell Metabolism https://t.co/Fo1QBrSCqt

Oct 6, 2020 · 366 followers View post →

Dr Ox

@krista_rantanen · X

Oct 5, 2020 · 1 like · 1,287 followers View post →

Kursad Turksen

@kursadturksen · X

#STEMCELL #HAIR #HAIRFOLLICLE Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co/aLyJeV1hU1

Sep 13, 2020 · 231 followers View post →

Marisol OI

@ib_ibarr · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Sep 10, 2020 · 8 shares · 84 followers View post →

UpToPhate

@UpToPhate · X

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle. https://t.co/lZsiQX6PHI

Sep 10, 2020 · 1 like · 1 share · 195 followers View post →

Hypoxia Adaptation

@hypoxiapapers · X

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle. https://t.co/brufVCXunI

Sep 10, 2020 · 678 followers View post →

VIJAY SONI

@sonivijay07 · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Sep 9, 2020 · 8 shares · 366 followers View post →

Alexis Lomakin, Ph.D. (אל) אַלעקסיס לאָמאַקין

@Alexis_Lomakin · X

RT @ShiriGurCohen: Stem cell fate plasticity driven by metabolic cues... super cool work!!!

Sep 9, 2020 · 2 shares · 3,643 followers View post →

Bartomeu Colom

@Bartomeu_Colom · X

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co/aCbCHBXfnL

Sep 9, 2020 · 1 like · 1,719 followers View post →

Björn Schumacher

@schumacherbj · X

RT @CECAD_:

Sep 9, 2020 · 2 shares · 18,898 followers View post →

Wickstrom-Lab

@WickstromLab · X

RT @CECAD_:

Sep 9, 2020 · 2 shares · 3,726 followers View post →

CECAD Cologne

@CECAD_ · X

Sep 9, 2020 · 19 likes · 2 shares · 3,235 followers View post →

Alessandro Ori

@AOri_lab · X

RT @ShiriGurCohen: Stem cell fate plasticity driven by metabolic cues... super cool work!!!

Sep 9, 2020 · 2 shares · 1,449 followers View post →

TVPLab

@TVPLab · X

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle: Cell Metabolism https://t.co/wKPH9vuRng

Sep 9, 2020 · 1,599 followers View post →

Dr. Biswapriya Misra

@BiswapriyaMisra · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Sep 9, 2020 · 8 shares · 5,763 followers View post →

Alexis Lomakin, Ph.D. (אל) אַלעקסיס לאָמאַקין

@Alexis_Lomakin · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Sep 8, 2020 · 8 shares · 3,643 followers View post →

Shiri Gur-Cohen

@ShiriGurCohen · X

Stem cell fate plasticity driven by metabolic cues... super cool work!!!

Sep 8, 2020 · 15 likes · 2 shares · 2,735 followers View post →

Hung-Jen Chen (Oliver), MD. PhD. NerD.

@oliverch77 · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Sep 8, 2020 · 8 shares · 601 followers View post →

Eduardo Silva-Pavez

@EduSilvaPavez · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Sep 8, 2020 · 8 shares · 134 followers View post →

Dr Mazen Ghaith

@mm_ghaith · X

RT @Cell_Metabolism: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co…

Sep 8, 2020 · 8 shares · 2,827 followers View post →

Cell Metabolism

@Cell_Metabolism · X

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle https://t.co/U0npvfq3aT

Sep 8, 2020 · 35 likes · 8 shares · 53,672 followers View post →

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Hair Follicle Stem Cell Metabolism and Regeneration Mechanisms

Role of Glutamine Metabolism in Hair Follicle Stem Cell Maintenance