Br J Cancer November 2020 PMID 32929196

The effect of vitamin D supplementation on survival in patients with colorectal cancer: systematic review and meta-analysis of randomised controlled trials.

Peter G Vaughan-Shaw, Louis F Buijs, James P Blackmur, Evi Theodoratou, Lina Zgaga, Farhat V N Din, Susan M Farrington, Malcolm G Dunlop

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Mentions

Peak: 26 in Sep 2020

across 3 sources since Sep 2020

Extended reach

95,800

potential audience

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1,893

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Sep 2020 – Sep 2025

Where it's discussed

News27 articles
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AI synopsis

What people are saying

The discussions generally demonstrate positive reactions to the publication, with posts highlighting its significance, such as 'interesting study from our colon cancer genetics team', and references to its publication in the British Journal of Cancer. The tone and choice of words reflect a mix of professional interest and recognition of its potential clinical relevance, contributing to their overall moderate but meaningful engagement with the research findings.

AgreementModerate agreement

Most posts acknowledge the study's positive findings regarding vitamin D and colorectal cancer survival, with phrases like 'estudio favorece' (study favors) and references to the benefits observed.

InterestHigh interest

The discussions indicate high curiosity, especially with mentions of clinical implications and interest from research teams, suggesting relevance and engagement with the topic.

EngagementModerate engagement

Several posts share details about the publication, such as referencing the journal and specific findings, showing a moderate level of detailed discussion rather than superficial mentions.

ImpactModerate impact

These discussions seem to perceive the article as potentially influential, citing its publication in a reputable journal and emphasizing the importance of vitamin D's role in cancer survival, though they do not directly state it will change practice yet.

Abstract in brief

The systematic review and meta-analysis of seven RCTs involving 957 CRC patients found that vitamin D supplementation is associated with a 30% reduction in colorectal cancer mortality and improves survival outcomes, particularly in progression-free survival and CRC-specific survival.
The analysis showed no significant heterogeneity or publication bias, suggesting consistent benefits across studies, although two trials were excluded due to high bias risk.
The findings support the potential clinical benefit of vitamin D supplementation for CRC patients, but larger, well-designed trials are needed to determine optimal dosing and to confirm these effects in real-world scenarios.]

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All mentions

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