J Endocrinol Invest June 2021 PMID 32946077

Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodiesterase's type 5 inhibitors on DHT response to exercise-related stress.

P Sgrò, C Minganti, M Lista, C Antinozzi, M Cappa, Y Pitsiladis, F Pigozzi, L Di Luigi

Mentions

35
Peak: 16 in Mar 2024
across 3 sources since Sep 2020

Extended reach

445,407
potential audience

Total likes

1,463

Video views

54,320

Mentions per month

Sep 2020 – Apr 2025

Where it's discussed

  • X / Twitter25 posts
  • Reddit8 posts
  • YouTube2 videos

AI synopsis

What people are saying

Discussions include mentions of how antioxidants like NAC and quercetin might affect hormonal responses, questions about personal experiences with DHT levels, and references to the study itself, demonstrating curiosity and moderate engagement with the topic of hormonal responses to exercise and inhibitors. The tone varies from scientific curiosity to personal reflection, but few examples indicate transformative implications for medicine or public health.

AgreementModerate agreement

Many discussions reference the specific hormonal responses and the effects of inhibitors like PDE5, indicating general agreement or at least acknowledgment of the study's findings.

InterestModerate interest

Participants show curiosity about how antioxidants and substances like creatine influence DHT, reflecting moderate interest in hormonal regulation during exercise.

EngagementModerate engagement

Some discussions delve into the biological mechanisms and personal reactions, revealing a moderate level of engagement with the research details.

ImpactNeutral impact

There is limited evidence of the broader impact of the publication; most interactions are more personal or speculative than emphasizing significant societal or scientific changes.

Abstract in brief

  • During the study, other androgens like testosterone and DHEAS also showed increases after exercise, independent of whether participants took a placebo or tadalafil, indicating that exercise naturally boosts these hormones.
  • The findings imply that DHT, alongside testosterone, may help the body adapt to high-intensity exercise, and that the enzyme pathways involved in steroid production, as well as nitric oxide signaling influenced by tadalafil, could modulate these hormonal responses during physical stress.]

Top posts

Most liked on X and Bluesky
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodiesterase's type 5 inhibitors on DHT response to exercise-related stress https://t.co/JlTtLvYfQv Cardio increases DHT, but PDE5 inhibitors like Viagra and https://t.co/N1cnEn2lD3

Mar 9, 2024 · 184 likes · 18 shares · 133,546 followers View post →
Jose Antonio PhD
@JoseAntonioPhD · X

Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodiesterase's type 5 inhibitors on DHT response to exercise-related stress. https://t.co/ktINZjajZe

Mar 22, 2023 · 10 likes · 22,234 followers View post →
Nick Krontiris
@nick_krontiris · X

Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodiesterase's type 5 inhibitors on DHT response to exercise-related stress https://t.co/WDoiWbYSme #hormones #exercise #muscle #strength #lift #hiit

Sep 22, 2020 · 3 likes · 19,483 followers View post →
UpToPhate
@UpToPhate · X

Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodiesterase's type 5 inhibitors on DHT response to exercise-related stress. https://t.co/zvW51IY1hG

Sep 20, 2020 · 2 likes · 1 share · 192 followers View post →
IberianCitizen
@IberianCitizen · X

⛲️ https://t.co/6jHefRVEdY

Sep 20, 2020 · 1 like · 12,906 followers View post →
IberianCitizen
@IberianCitizen · X

@P_I_C_A_6_9 Bueno te pongo la traducción de google, es que se me olvidó poner el enlace en el primer tuit

Sep 21, 2020 · 1 like · 12,906 followers View post →

All mentions

snafflehound
@BTSnaffleHound · X

@BenWestgate_ @BowTiedUM Any chance antioxidants could blunt 5AR this much? I've been cycling NAC, quercetin and others the past couple years. Also, I came across this which could be related. https://t.co/XbI6GCpqK3

Apr 27, 2025 · 276 followers View post →
Ludicrous - 漱石
@ludicrousdefect · X

@curiousCNA @dompeet_ @dfwprosportsjon @cremieuxrecueil https://t.co/JT5h05QEjQ This was the original video that informed me on the issue, including one linked in the description. IMO he's a bit biased in favor of creatine, but the first linked study makes a pretty strong case against creatine if you care about your hair. YMMV.

Nov 5, 2024 · 236 followers View post →
Master Ben Westgate
@BenWestgate_ · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Aug 3, 2024 · 18 shares · 13,740 followers View post →
Mauricio--
@Juns884 · X

@zeta_globin No, but yes https://t.co/TgxsIHggzE It doesn't, it shouldn't but it happens to me, and many others, so I'd rather not

Jun 25, 2024 · 439 followers View post →
Patricia
@plivestrong · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 2,261 followers View post →
Luna Capital LLC
@JavierXBT7 · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 1,015 followers View post →
Evan
@EvanH176 · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 554 followers View post →
Turtle & Ape Capital Management
@TNA_Capital · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 3,386 followers View post →
bloodybricks
@bloodybricks · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 339 followers View post →
Burhan
@Burhan_DO · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 73 followers View post →
Hawthorn
@neuroandrogen · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 517 followers View post →
BowTied Biohacker
@BowTiedUM · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 114,723 followers View post →
Deidra Lowe
@DeidraLowe2 · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 731 followers View post →
yuh
@suninmebalzrn · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 1 followers View post →
kike
@FUENTESMANZULLI · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 249 followers View post →
Devin Nunes' Cabrito Fella - NOT a nazi
@tallulahhulabel · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 1,294 followers View post →
Richard
@PGC1a_RB · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 14,931 followers View post →
Remnant | MD
@RemnantMd · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 32,625 followers View post →
Buckeye089
@buckeye089 · X

RT @Grimhood: Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodie…

Mar 9, 2024 · 18 shares · 1,737 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodiesterase's type 5 inhibitors on DHT response to exercise-related stress https://t.co/JlTtLvYfQv Cardio increases DHT, but PDE5 inhibitors like Viagra and https://t.co/N1cnEn2lD3

Mar 9, 2024 · 184 likes · 18 shares · 133,546 followers View post →
Jose Antonio PhD
@JoseAntonioPhD · X

Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodiesterase's type 5 inhibitors on DHT response to exercise-related stress. https://t.co/ktINZjajZe

Mar 22, 2023 · 10 likes · 22,234 followers View post →
Nick Krontiris
@nick_krontiris · X

Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodiesterase's type 5 inhibitors on DHT response to exercise-related stress https://t.co/WDoiWbYSme #hormones #exercise #muscle #strength #lift #hiit

Sep 22, 2020 · 3 likes · 19,483 followers View post →
IberianCitizen
@IberianCitizen · X

@P_I_C_A_6_9 Bueno te pongo la traducción de google, es que se me olvidó poner el enlace en el primer tuit

Sep 21, 2020 · 1 like · 12,906 followers View post →
IberianCitizen
@IberianCitizen · X

⛲️ https://t.co/6jHefRVEdY

Sep 20, 2020 · 1 like · 12,906 followers View post →
UpToPhate
@UpToPhate · X

Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodiesterase's type 5 inhibitors on DHT response to exercise-related stress. https://t.co/zvW51IY1hG

Sep 20, 2020 · 2 likes · 1 share · 192 followers View post →
60 minute se zyada cardio karne se DHT level kam hota hai aur ...
Reddit

... 10.1007@s40618-020-01409-z.pdf · https://perfecthairhealth.com/exercise-and-hair-loss/. Yeh maine AI se pooch kar pata kiya hai ki kya aerobic ...

Feb 20, 2025 View →
Cardio for more than 60 minutes reduces DHT levels and improve ...
Reddit

... 10.1007@s40618-020-01409-z.pdf · https://perfecthairhealth.com/exercise-and-hair-loss/. I got this from ai researching if aerobic exercise can ...

Feb 20, 2025 View →
Cardio por mais de 60 minutos reduz os níveis de DHT e melhora o ...
Reddit

... 10.1007@s40618-020-01409-z.pdf · https://perfecthairhealth.com/exercise-and-hair-loss/. Isto veio da IA a pesquisar se exercício aeróbico pode ...

Feb 20, 2025 View →
Cardio i över 60 minuter minskar DHT-nivåerna och förbättrar ...
Reddit

... 10.1007@s40618-020-01409-z.pdf · https://perfecthairhealth.com/exercise-and-hair-loss/. Jag fick det här från AI när jag undersökte om aerob ...

Feb 20, 2025 View →
Does whey protein and creatine aggravate hair loss? : r/tressless
Reddit

https://link.springer.com/article/10.1007/s40618-020-01409-z · https://journals.physiology.org/doi/full/10.1152/japplphysiol.01419.2012 · More ...

Dec 14, 2023 View →
Dihydrotestosteron (DHT) øker raskt etter maksimal aerob trening ...
Reddit

... virkelige helten her, og det funker med denne artikkelen. https://sci-hub.se/10.1007/s40618-020-01409-z · lurkzone. OP (opprinnelig bidragsyter) ...

Nov 16, 2022 View →
Дигидротестостерон (ДГТ) быстро увеличивается после ...
Reddit

... Divallo. • 3 г. назад. Вот настоящий MVP, и с этой бумагой работает. https://sci-hub.se/10.1007/s40618-020-01409-z · lurkzone. Автор ...

Nov 16, 2022 View →
Exercise might raise DHT levels and oxidative stress in the skin ...
Reddit

https://link.springer.com/article/10.1007/s40618-020-01409-z · https://journals.physiology.org/doi/full/10.1152/japplphysiol.01419.2012 · https ...

Oct 12, 2022 View →