Signal Transduct Target Ther September 2020 PMID 32968059

Recent advances in the development of protein-protein interactions modulators: mechanisms and clinical trials.

Haiying Lu, Qiaodan Zhou, Jun He, Zhongliang Jiang, Cheng Peng, Rongsheng Tong, Jianyou Shi

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Mentions

11
Peak: 3 in Sep 2020
across 4 sources since Sep 2020

Extended reach

519,893
potential audience

Total likes

22

Video views

174

Mentions per month

Sep 2020 – Feb 2025

Where it's discussed

  • X / Twitter5 posts
  • YouTube2 videos
  • News2 articles
  • Blogs2 articles

AI synopsis

What people are saying

Across the discussions, there is recognition of recent advances in PPI modulators, with examples like efforts to guide future drug design and references to mechanisms and clinical trials. The tone is professional and optimistic but remains focused on technical progress, contributing to a moderate overall outlook on the article's significance.

AgreementModerate agreement

The discussions generally acknowledge the significance of recent advancements in PPI modulators, with some emphasizing their potential for guiding future drug design, indicating moderate agreement on the importance.

InterestModerate interest

Participants show a moderate level of interest by mentioning hopes and future guidance, but the overall tone remains somewhat technical and not highly passionate.

EngagementModerate engagement

Comments reflect a basic level of engagement, such as noting developments and referencing mechanisms, but lack deep analysis or extensive discussion.

ImpactModerate impact

The impact is viewed as noteworthy but not revolutionary, with comments highlighting potential future applications rather than immediate clinical breakthroughs.

Abstract in brief

  • Recent advances in understanding protein-protein interactions (PPIs) highlight their crucial roles in biological processes, with abnormal PPIs linked to diseases like cancer and neurodegenerative disorders.
  • Targeting PPIs for disease treatment is a promising but challenging area in drug development, with some modulators now reaching clinical trials and even approval.
  • The research focuses on various PPI modulators such as small molecules, peptides, and antibodies, offering insights for designing new drugs to better manage related diseases.]

Top posts

Most liked on X and Bluesky
Chemistry News
@ChemistryNews · X

Recent advances in the development of protein–protein interactions modulators: mechanisms and clinical trials https://t.co/Wbhy6OogJK https://t.co/gdRg8s1HJr

Sep 23, 2020 · 10 likes · 2 shares · 517,875 followers View post →
闘う鬼百合
@tosyl_chloride · X

はい https://t.co/uWIfXpyzh0

Mar 23, 2023 · 1 like · 398 followers View post →
Francisco Villalba
@FcoVillalba · X

RT @ChemistryNews: Recent advances in the development of protein–protein interactions modulators: mechanisms and clinical trials https://t.…

Sep 23, 2020 · 2 shares · 1,055 followers View post →
Jorma Haarala
@haaralajorma · X

Recent advances in PPIs (protein-protein interactions) modulators, including small molecules, peptides, and antibodies, hoping to provide some guidance to the design of novel drugs targeting PPIs in the future. https://t.co/WEka9l8qXN

Oct 5, 2020 · 229 followers View post →

All mentions

闘う鬼百合
@tosyl_chloride · X

はい https://t.co/uWIfXpyzh0

Mar 23, 2023 · 1 like · 398 followers View post →
Jorma Haarala
@haaralajorma · X

Recent advances in PPIs (protein-protein interactions) modulators, including small molecules, peptides, and antibodies, hoping to provide some guidance to the design of novel drugs targeting PPIs in the future. https://t.co/WEka9l8qXN

Oct 5, 2020 · 229 followers View post →
Sebastian Echeverri Florez
@macaco142857 · X

RT @ChemistryNews: Recent advances in the development of protein–protein interactions modulators: mechanisms and clinical trials https://t.…

Sep 23, 2020 · 2 shares · 150 followers View post →
Francisco Villalba
@FcoVillalba · X

RT @ChemistryNews: Recent advances in the development of protein–protein interactions modulators: mechanisms and clinical trials https://t.…

Sep 23, 2020 · 2 shares · 1,055 followers View post →
Chemistry News
@ChemistryNews · X

Recent advances in the development of protein–protein interactions modulators: mechanisms and clinical trials https://t.co/Wbhy6OogJK https://t.co/gdRg8s1HJr

Sep 23, 2020 · 10 likes · 2 shares · 517,875 followers View post →