High speed microscopy video showing a method to elongate cells by rapid flow through a microfluidic chamber toward a cavity. https://t.co/EddFnwINXW by Aram J. Chung @ac467 Korea University /CJD https://t.co/PnXQ4MXwg2
Microfluidic Cell Stretching for Highly Effective Gene Delivery into Hard-to-Transfect Primary Cells.
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Oct 2020 – Nov 2020Where it's discussed
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X / Twitter14 posts
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YouTube3 videos
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News2 articles
AI synopsis
What people are saying
The discussions emphasize the innovative microfluidic method for gene delivery, highlighting its high efficiency and practical advantages such as low cost and rapid operation. Words like 'highly effective,' 'superior,' and 'achievement' reflect strong positive sentiment and recognition of potential impact, while technical references indicate substantial engagement with the research specifics.
Most discussions express positive support and approval of the article’s findings, indicating general agreement with its significance.
The discussions demonstrate high interest through mentions of specific techniques, high efficiency, and technological innovation.
Posts reference technical details like microfluidic flow patterns and cell stretching, showing moderate to deep engagement with the research methods.
The emphasis on high delivery efficiency, cost-effectiveness, and potential for advancements suggests that the discussion sees this work as impactful and influential.
Abstract in brief
- Cell therapy and cellular engineering traditionally rely on methods like electroporation or viral transduction for internalizing materials into primary cells, but these methods have limitations such as high toxicity and complexity.
- A new intracellular delivery platform using inertial flow in a T-junction microchannel effectively stretches cells, allowing various nanomaterials (like plasmid DNA and nanoparticles) to be internalized into difficult-to-transfect cells.
- This innovative method shows up to 98% delivery efficiency, is cost-effective (less than $1), operates at high speed (1 million cells per minute), and minimizes disruption to cells, promising significant advancements in cell-based research.
Top posts
Most liked on X and BlueskyIn this recent article, the flow patterns in a #microfluidic T-junction #microchannel are used to achieve a high #transfection yield and delivery efficiency (up to 98%) which is superior to many of the current technologies. https://t.co/O3ggrbfxPT #genedelivery
It turned out well :) #acsnano #intracellulardelivery #transfection #genedelivery #microfluidics @acsnano https://t.co/Nu3zVNaTx5 https://t.co/PGIGM4XMWa
RT @uFluidix: In this recent article, the flow patterns in a #microfluidic T-junction #microchannel are used to achieve a high #transfectio…
RT @ac467: It turned out well :) #acsnano #intracellulardelivery #transfection #genedelivery #microfluidics @acsnano https://t.co/Nu3zVNaT…
RT @uFluidix: In this recent article, the flow patterns in a #microfluidic T-junction #microchannel are used to achieve a high #transfectio…
All mentions
Innovative Microfluidic Technique Enhances Gene Delivery Efficiency
This video explores a novel microfluidic cell stretching method that effectively introduces nanomaterials into primary cells, achieving up to 98% delivery efficiency while reducing cell disruption and costs.
Microfluidic Cell Stretching for Efficient Gene Delivery
This video discusses a new method using inertial flow microchannels to stretch cells for high-efficiency gene delivery, overcoming limitations of traditional techniques and enabling rapid, cost-effective cell…
Efficient Nanoparticle Delivery Using Microfluidic Cell Stretching
This video discusses a novel cell delivery platform utilizing inertial flow in a T-junction microchannel to enhance nanoparticle internalization into primary cells. The method achieves up to 98% efficiency, operates…
RT @ac467: It turned out well :) #acsnano #intracellulardelivery #transfection #genedelivery #microfluidics @acsnano https://t.co/Nu3zVNaT…
RT @ac467: It turned out well :) #acsnano #intracellulardelivery #transfection #genedelivery #microfluidics @acsnano https://t.co/Nu3zVNaT…
It turned out well :) #acsnano #intracellulardelivery #transfection #genedelivery #microfluidics @acsnano https://t.co/Nu3zVNaTx5 https://t.co/PGIGM4XMWa
RT @uFluidix: In this recent article, the flow patterns in a #microfluidic T-junction #microchannel are used to achieve a high #transfectio…
RT @uFluidix: In this recent article, the flow patterns in a #microfluidic T-junction #microchannel are used to achieve a high #transfectio…
RT @uFluidix: In this recent article, the flow patterns in a #microfluidic T-junction #microchannel are used to achieve a high #transfectio…
RT @uFluidix: In this recent article, the flow patterns in a #microfluidic T-junction #microchannel are used to achieve a high #transfectio…
RT @uFluidix: In this recent article, the flow patterns in a #microfluidic T-junction #microchannel are used to achieve a high #transfectio…
RT @uFluidix: In this recent article, the flow patterns in a #microfluidic T-junction #microchannel are used to achieve a high #transfectio…
In this recent article, the flow patterns in a #microfluidic T-junction #microchannel are used to achieve a high #transfection yield and delivery efficiency (up to 98%) which is superior to many of the current technologies. https://t.co/O3ggrbfxPT #genedelivery
RT @acsnano: High speed microscopy video showing a method to elongate cells by rapid flow through a microfluidic chamber toward a cavity. h…
High speed microscopy video showing a method to elongate cells by rapid flow through a microfluidic chamber toward a cavity. https://t.co/EddFnwINXW by Aram J. Chung @ac467 Korea University /CJD https://t.co/PnXQ4MXwg2
[ASAP] Microfluidic Cell Stretching for Highly Effective Gene Delivery into Hard-to-Transfect Primary Cells https://t.co/0Sb8QeemNY
RT @ac467: Our work on microfluidic gene delivery into hard-to-transfect primary cells published in @acsnano! https://t.co/NGVwIWTRHb