Diabetologia January 2021 PMID 33043401

Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes.

Kimberly M Alonge, David A D'Alessio, Michael W Schwartz

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AI synopsis

What people are saying

In the discussions, contributors frequently reference the publication's insights, mentioning topics such as the restoration of normal glucose levels through brain therapy. Phrases like 'fascinating animal data' and 'potential brain-centered defects' indicate enthusiasm and seriousness regarding the future impact of this research. The tone remains largely optimistic, underscoring a sense of urgency and importance in exploring these findings for practical applications.

AgreementModerate agreement

Most discussions reflect a general support for the findings presented in the publication.

InterestHigh interest

Contributors show a strong interest in the brain's role in regulating glucose levels, highlighting its relevance to diabetes research.

EngagementModerate engagement

While some users share details about studies, the overall depth of discussion varies, with less intricate analysis.

ImpactHigh impact

Many contributors perceive the implications of this research as significant for treating type 2 diabetes, emphasizing the potential for impactful therapies.

Abstract in brief

The brain plays a critical role in maintaining normal blood glucose levels and its dysfunction may contribute to the development of type 2 diabetes.
Evidence suggests that the brain can sense blood glucose changes similarly to the pancreas, and issues with this sensing system can lead to a higher defended level of glucose in diabetes.
The link between obesity and type 2 diabetes may stem from shared neurocircuitry problems affecting both energy and glucose homeostasis, highlighting the importance of the brain's feedback mechanisms in these conditions.

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All mentions

Brain's Role in Metabolism and Diabetes Control

Professor Michael Schwartz MD examines the critical role of the brain in maintaining blood glucose levels and its impact on appetite regulation. He discusses how dysfunction in this system can lead to obesity and type 2…

Research Features · Sep 21, 2022 600 views

Brain's Role in Metabolism and Diabetes Regulation

Professor Michael Schwartz MD explores how the brain maintains blood glucose levels and regulates appetite. His insights reveal how defects in these systems can lead to obesity and diabetes, emphasizing the importance…

Sci60 · Sep 25, 2024 39 views

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Gastón F Rodríguez

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Control cerebral de los niveles de glucosa en sangre: implicaciones para la patogénesis de la diabetes tipo 2 https://t.co/81exkkEcfx

Aug 12, 2022 · 1 like · 1,155 followers View post →

Luciana El-Kadre MD MSc PhD FACS

@elkadre · X

preclinical evidence that in T2D the defended level of blood glucose can be restored to normal by therapies that restore the brain’s ability to properly sense the circulating glucose level https://t.co/TIC2w5k64B

Jan 14, 2021 · 1 like · 395 followers View post →

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LifeScan Diabetes Institute

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Michael Riddell, PhD

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Diabetologia

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Revista Mexicana Endocrino Metabolismo & Nutricion

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Abdul-Wahid Mohammad

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Cristina de la Mata

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Brett Gordon

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Jose Jimenez-Vega

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Rodrigo Nunes Cal

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Tune H. Pers

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Oct 20, 2020 · 9 shares · 1,371 followers View post →

Kimberly Alonge

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DiabetesEtNous

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Wouter Franssen

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