December 2020 PMID 33065824

A systematic review and meta-analysis of the efficacy of intravenous ketamine infusion for treatment resistant depression: January 2009 - January 2019.

Walter S Marcantoni, Bertine Sandra Akoumba, Maggy Wassef, Julie Mayrand, Hinatea Lai, Stéphane Richard-Devantoy, Sylvie Beauchamp

Mentions

63
Peak: 6 in Jan 2023
across 4 sources since Jan 2021

Extended reach

117,677
potential audience

Total likes

36

Video views

374

Mentions per month

Jan 2021 – Dec 2024

Where it's discussed

  • News45 articles
  • X / Twitter12 posts
  • YouTube4 videos
  • Blogs2 articles

AI synopsis

What people are saying

The posts demonstrate a generally positive sentiment towards the article, highlighting the strong short-term effects of ketamine treatment and referencing real-world clinical success, which shows a high level of engagement. Several discussions focus on detailed aspects like the type of ketamine used and the need for ongoing research, illustrating both interest and active involvement in understanding the implications of the findings.

AgreementModerate agreement

Most posts express positive views about the evidence supporting ketamine's effectiveness, with some emphasizing clinical success and anecdotal responses.

InterestModerate interest

Discussions show moderate curiosity, especially regarding specific details like the type of ketamine used and long-term strategies.

EngagementModerate engagement

Posts reference multiple aspects such as meta-analysis, clinical practice, and the need for further research, indicating active engagement.

ImpactModerate impact

The social discussions suggest the article influences perceptions around treatment approaches; some call for more widespread consideration and further studies.

Abstract in brief

  • The systematic review and meta-analysis examined the effectiveness of intravenous ketamine in treating treatment-resistant depression (TRD) over a decade, highlighting a strong short-term benefit, especially within 24 hours of a single infusion.
  • Ketamine's antidepressant effects tend to diminish after a week, but multiple infusions can extend and enhance its benefits.
  • While findings support ketamine's rapid relief of depressive symptoms, more research is needed to understand its long-term safety, efficacy, and potential risks.]

Top posts

Most liked on X and Bluesky
Andreas Wahl
@andreas_wahl · X

@joarhalvorsen For de som er interessert i evidensen: https://t.co/J6kSsZdXUW https://t.co/TK5m7ip6mN https://t.co/vaDi5WFY4z https://t.co/miXnQQnAZv https://t.co/ppqoGKWcMR

Jan 22, 2023 · 14 likes · 4 shares · 761 followers View post →
Dr. Carlos Arnaud
@carlos_arnaud · X

@diariodeunloc0 @drlangosta @JRBneuropsiq @dranibalacosta @drbernardong https://t.co/HHpEM0KF3S

Jan 10, 2021 · 5 likes · 21,256 followers View post →
Mike Hart, M.D
@drmikehart · X

@VPrasadMDMPH What type of ketamine was used? I have a feeling they used S ketamine and not a combination of R/S ketamine. Multiple meta-analyses suggest that K is effective, and anecdotally, the patients I've prescribed it to have responded extremely well. https://t.co/GNSwEUDKv5

May 6, 2023 · 3 likes · 66,394 followers View post →
Raymond Lam
@DrRaymondLam · X

@ProfRobHoward @alokvkulkarni @shyambhat @lena_pl For IV ketamine, the meta-analyzed effect size of single-dose trials is very large (latest of 8 here). The problem is that there is little study of maintenance strategies after a short series of infusions. https://t.co/vDMqG5sneR https://t.co/wITP1RTAfE

Mar 19, 2021 · 3 likes · 2,134 followers View post →
Dr. Carlos Arnaud
@carlos_arnaud · X

@joannamoncrieff Meta-analysis needed to be read https://t.co/No3uxZBY08 But most, U need to see patients who benefit from these treatment in Psychiatry I have seen the spectacular efficacy during this last 7yrs in patients with depression or suicidal ideation @rogersmcintyre any comment ?

Oct 10, 2022 · 1 like · 21,256 followers View post →
NoName
@NoName30750023 · X

RT @andreas_wahl: @joarhalvorsen For de som er interessert i evidensen: https://t.co/J6kSsZdXUW https://t.co/TK5m7ip6mN https://t.co/vaDi…

Jan 22, 2023 · 4 shares · 2,312 followers View post →

All mentions

Social Skeptic
@DaSocialSkeptic · X

@ArtCandee @donlemon It's got strong clinical rationale, alongside a number of psychoactive substances under review at John Hopkins. Here is some meta analysis on the topic: https://t.co/ur6Xo4GXGd

Mar 20, 2024 · 290 followers View post →
Mike Hart, M.D
@drmikehart · X

@VPrasadMDMPH What type of ketamine was used? I have a feeling they used S ketamine and not a combination of R/S ketamine. Multiple meta-analyses suggest that K is effective, and anecdotally, the patients I've prescribed it to have responded extremely well. https://t.co/GNSwEUDKv5

May 6, 2023 · 3 likes · 66,394 followers View post →
Catalina
@CKallisto · X

RT @andreas_wahl: @joarhalvorsen For de som er interessert i evidensen: https://t.co/J6kSsZdXUW https://t.co/TK5m7ip6mN https://t.co/vaDi…

Jan 24, 2023 · 4 shares · 599 followers View post →
NoName
@NoName30750023 · X

RT @andreas_wahl: @joarhalvorsen For de som er interessert i evidensen: https://t.co/J6kSsZdXUW https://t.co/TK5m7ip6mN https://t.co/vaDi…

Jan 22, 2023 · 4 shares · 2,312 followers View post →
Dr. StrangeLove
@Basboy333 · X

RT @andreas_wahl: @joarhalvorsen For de som er interessert i evidensen: https://t.co/J6kSsZdXUW https://t.co/TK5m7ip6mN https://t.co/vaDi…

Jan 22, 2023 · 4 shares · 518 followers View post →
Seretoninen
@JTFS84 · X

RT @andreas_wahl: @joarhalvorsen For de som er interessert i evidensen: https://t.co/J6kSsZdXUW https://t.co/TK5m7ip6mN https://t.co/vaDi…

Jan 22, 2023 · 4 shares · 991 followers View post →
Andreas Wahl
@andreas_wahl · X

@joarhalvorsen For de som er interessert i evidensen: https://t.co/J6kSsZdXUW https://t.co/TK5m7ip6mN https://t.co/vaDi5WFY4z https://t.co/miXnQQnAZv https://t.co/ppqoGKWcMR

Jan 22, 2023 · 14 likes · 4 shares · 761 followers View post →
Мет
@metyslav · X

@morsmorded >хоч якогось наукового підґрунтя https://t.co/usPSMT8out https://t.co/A7Dr0qOwxQ https://t.co/a8HPjNvgW5 https://t.co/DFQCm5svMR https://t.co/WrLOSpVGfo https://t.co/DDPmluAa44 ..і ще мільйон наукових статей, які загалом доводять що ви несете дурню, яку, схоже, самі і вигадали https://t.co/Yyu1bAUWLs

Jan 10, 2023 · 750 followers View post →
Dr. Carlos Arnaud
@carlos_arnaud · X

@joannamoncrieff Meta-analysis needed to be read https://t.co/No3uxZBY08 But most, U need to see patients who benefit from these treatment in Psychiatry I have seen the spectacular efficacy during this last 7yrs in patients with depression or suicidal ideation @rogersmcintyre any comment ?

Oct 10, 2022 · 1 like · 21,256 followers View post →
K.Zaraki
@MarcusNafstad · X

@MalaWolf To burde vel holde for nå… https://t.co/UHKQsJxT0t https://t.co/QkUIxE5bUt

Oct 24, 2021 · 4 followers View post →
Raymond Lam
@DrRaymondLam · X

@ProfRobHoward @alokvkulkarni @shyambhat @lena_pl For IV ketamine, the meta-analyzed effect size of single-dose trials is very large (latest of 8 here). The problem is that there is little study of maintenance strategies after a short series of infusions. https://t.co/vDMqG5sneR https://t.co/wITP1RTAfE

Mar 19, 2021 · 3 likes · 2,134 followers View post →
Dr. Carlos Arnaud
@carlos_arnaud · X

@diariodeunloc0 @drlangosta @JRBneuropsiq @dranibalacosta @drbernardong https://t.co/HHpEM0KF3S

Jan 10, 2021 · 5 likes · 21,256 followers View post →