Eur J Nutr August 2021 PMID 33084958

Long-term effects of increasing omega-3, omega-6 and total polyunsaturated fats on inflammatory bowel disease and markers of inflammation: a systematic review and meta-analysis of randomized controlled trials.

Sarah M Ajabnoor, Gabrielle Thorpe, Asmaa Abdelhamid, Lee Hooper

Mentions

29
Peak: 8 in Oct 2020
across 4 sources since Oct 2020

Extended reach

75,759
potential audience

Total likes

181

Video views

5,097

Mentions per month

Oct 2020 – Dec 2024

Where it's discussed

  • X / Twitter22 posts
  • News3 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

Discussions exhibit a careful examination of research data, with posts like '@logicalbaseline' asserting the lack of evidence against seed oils, and others referencing systematic reviews indicating minimal effects of omega fats on inflammation. The tone is analytical and cautious, emphasizing evidence-based debates and referencing specific studies like those from 'Eur J Nutr.' and 'Mo Med.', which reflects moderate interest and engagement without a strong consensus on the article's implications.

AgreementNeither agree nor disagree

The discussions reflect mixed opinions, with some posts questioning the evidence and others referencing studies supporting limited or no effects, leading to a neutral overall stance.

InterestModerate interest

Posts show moderate curiosity by referencing specific studies and highlighting key findings about PUFAs and inflammation.

EngagementModerate engagement

Participants actively cite research articles, question claims, and share personal interpretations, indicating thoughtful engagement.

ImpactNeutral impact

While some posts emphasize the conflicting evidence, the overall discussions do not seem to significantly influence broader public perceptions or policy, suggesting a moderate impact.

Abstract in brief

  • This systematic review and meta-analysis examined the long-term effects of omega-3, omega-6, and total polyunsaturated fats (PUFA) on inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, focusing on diagnosis, relapse, severity, treatment outcomes, quality of life, and inflammatory markers.
  • The review included 83 randomized controlled trials with over 41,000 participants and found that increasing long-chain omega-3 may reduce the risk of IBD relapse and worsening, and decrease certain inflammatory markers like ESR, but may also increase the risk of IBD diagnosis; overall, evidence was low quality.
  • The findings suggest that supplementing with PUFAs has little to no significant impact on preventing or treating IBD, indicating limited support for using these fats to modify long-term inflammation in these conditions.]

Top posts

Most liked on X and Bluesky
Reijo Laatikainen
@Reijo_RD_FIN · X

Both omega-3 and 6 fatty acids have have very meager effects on inflammation in Crohn’s disease and ulcerative colitis. Meta-analysis of RCTs. Do not put your money on fish oil. No reason to avoid omega-6 FAs either in context of IBD https://t.co/7tSbiejyIo

Oct 22, 2020 · 23 likes · 5 shares · 4,611 followers View post →
Michael Albert, MD
@MichaelAlbertMD · X

PUFAs: long-term data suggest little to no effect on inflammation in humans. https://t.co/2Kjbdyuoer

Nov 18, 2021 · 12 likes · 2 shares · 15,921 followers View post →
Alex Corindia
@Alex_HPL · X

@logicalbaseline @hubermanlab He asked for evidence that seed oils are bad. I'm saying there is no evidence. Here's evidence AGAINST the claim that seed oils are bad Use your exquisite reading skills: https://t.co/Vu9QtQs9Aj https://t.co/KCLUuLXts7 https://t.co/tn0RGHYcn9 https://t.co/wiVwVTVaVH

Dec 10, 2024 · 9 likes · 1,893 followers View post →
Nick Krontiris
@nick_krontiris · X

Long-term effects of increasing omega-3, omega-6 and total polyunsaturated fats on inflammatory bowel disease and markers of inflammation: a systematic review and meta-analysis of randomized controlled trials https://t.co/OiQxV9Sn7n #nutrition #diet #Omega3 #Omega6 #PUFAs

Oct 25, 2020 · 6 likes · 1 share · 18,972 followers View post →
Alex Corindia
@Alex_HPL · X

@Nozzels @hubermanlab https://t.co/q0s68D2xfi https://t.co/KCLUuLXts7 https://t.co/tn0RGHYcn9 https://t.co/77nX7xi6vJ https://t.co/6Tkv16ceAO https://t.co/vmhsqtDzn4 https://t.co/luDg4KP77r

Dec 10, 2024 · 4 likes · 1,893 followers View post →
Alex Corindia
@Alex_HPL · X

@twittmypants @hubermanlab Worth reading: https://t.co/q0s68D1ZpK Another one: We conclude that virtually no evidence is available from randomized, controlled intervention studies among healthy, noninfant human beings to show that addition of LA to the diet increases the concentration of inflammatory

Dec 10, 2024 · 4 likes · 1 share · 1,893 followers View post →

All mentions

Alex Corindia
@Alex_HPL · X

@logicalbaseline @hubermanlab He asked for evidence that seed oils are bad. I'm saying there is no evidence. Here's evidence AGAINST the claim that seed oils are bad Use your exquisite reading skills: https://t.co/Vu9QtQs9Aj https://t.co/KCLUuLXts7 https://t.co/tn0RGHYcn9 https://t.co/wiVwVTVaVH

Dec 10, 2024 · 9 likes · 1,893 followers View post →
David98
@twittmypants · X

RT @Alex_HPL: @twittmypants @hubermanlab Worth reading: https://t.co/q0s68D1ZpK Another one: We conclude that virtually no evidence is a…

Dec 10, 2024 · 1 share · 1,041 followers View post →
Alex Corindia
@Alex_HPL · X

@Nozzels @hubermanlab https://t.co/q0s68D2xfi https://t.co/KCLUuLXts7 https://t.co/tn0RGHYcn9 https://t.co/77nX7xi6vJ https://t.co/6Tkv16ceAO https://t.co/vmhsqtDzn4 https://t.co/luDg4KP77r

Dec 10, 2024 · 4 likes · 1,893 followers View post →
Alex Corindia
@Alex_HPL · X

@twittmypants @hubermanlab Worth reading: https://t.co/q0s68D1ZpK Another one: We conclude that virtually no evidence is available from randomized, controlled intervention studies among healthy, noninfant human beings to show that addition of LA to the diet increases the concentration of inflammatory

Dec 10, 2024 · 4 likes · 1 share · 1,893 followers View post →
ZKForTre
@ZKForTre · X

@Bellin546367 @RMiller77489648 Inflammation: https://t.co/Wi9pgSWI0K Glycemia: https://t.co/KeHn0k1TF3 https://t.co/j4smiv0mOh https://t.co/Bwt6568I8D https://t.co/2Hgj5yQtN3 https://t.co/0VhhmLbmzB https://t.co/2o6SqeyTuq https://t.co/V3XOlqASvg https://t.co/8RN9yJ3Maa Cvd: https://t.co/qcxUyeG9RH

May 26, 2024 · 2,753 followers View post →
Tom Ashcroft
@TheTomAshcroft · X

@Alicewants2know @SamaHoole Sarah M Ajabnoor et al. Eur J Nutr. 2021 Aug. https://t.co/A11djhUG6P Kevin L Fritsche. Mo Med. 2014 Jan-Feb https://t.co/pAvChKnL17 I saw in your bio it says ‘where is the evidence’ I am not one of your typical spray and pray nonesense so here are a couple for you.

Feb 24, 2024 · 1,713 followers View post →
Tom Ashcroft
@TheTomAshcroft · X

@cultistslayer @shelly_187 Sarah M Ajabnoor et al. Eur J Nutr. 2021 Aug. https://t.co/lzlKSreKke Kevin L Fritsche. Mo Med. 2014 Jan-Feb https://t.co/5VjhLwZLLh Please digest and come back to apologise.

Jan 3, 2024 · 1,713 followers View post →
Elaine Chiquette
@Chiquette3 · X

RT @MichaelAlbertMD: PUFAs: long-term data suggest little to no effect on inflammation in humans. https://t.co/2Kjbdyuoer

Nov 18, 2021 · 2 shares · 259 followers View post →
Jeffery Heileson
@jheilesonRD · X

RT @MichaelAlbertMD: PUFAs: long-term data suggest little to no effect on inflammation in humans. https://t.co/2Kjbdyuoer

Nov 18, 2021 · 2 shares · 781 followers View post →
Michael Albert, MD
@MichaelAlbertMD · X

PUFAs: long-term data suggest little to no effect on inflammation in humans. https://t.co/2Kjbdyuoer

Nov 18, 2021 · 12 likes · 2 shares · 15,921 followers View post →
Siran He (何思然), PhD, MSPH
@she_nutrition · X

Based on this review, #Omega3 #LCPUFA *may* reduce the relapse and worsening of #IBD (inflammatory bowel disease). Overall inconclusive. https://t.co/Wb4uorE8NR

Jul 13, 2021 · 1 like · 107 followers View post →
Jaxon Curada
@JasonC88766481 · X

Thoughts on this study? https://t.co/fgDOG17VQj @TuckerGoodrich @fire_bottle

Apr 29, 2021 · 107 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @SAjabnoor: Delighted to share our recent publication. Effects of incre…

Nov 1, 2020 · 1 share · 6,718 followers View post →
Sarah Ajabnoor
@SAjabnoor · X

Delighted to share our recent publication. Effects of increasing #omega3 #omega6 and #PUFA on #IBD and markers of inflammation #systematicreview #metaanalysis https://t.co/UMBE2zUMo1

Nov 1, 2020 · 1 like · 1 share · 126 followers View post →
Joaquín San José
@jsanjosea · X

RT @nick_krontiris: Long-term effects of increasing omega-3, omega-6 and total polyunsaturated fats on inflammatory bowel disease and marke…

Oct 25, 2020 · 1 share · 410 followers View post →
Nick Krontiris
@nick_krontiris · X

Long-term effects of increasing omega-3, omega-6 and total polyunsaturated fats on inflammatory bowel disease and markers of inflammation: a systematic review and meta-analysis of randomized controlled trials https://t.co/OiQxV9Sn7n #nutrition #diet #Omega3 #Omega6 #PUFAs

Oct 25, 2020 · 6 likes · 1 share · 18,972 followers View post →
Dr. Suzana Mantovani
@Tweet_Nutrition · X

RT @pronutritionist: Both omega-3 and 6 fatty acids have have very meager effects on inflammation in Crohn’s disease and ulcerative colitis…

Oct 23, 2020 · 5 shares · 4,575 followers View post →
Joaquín San José
@jsanjosea · X

RT @pronutritionist: Both omega-3 and 6 fatty acids have have very meager effects on inflammation in Crohn’s disease and ulcerative colitis…

Oct 23, 2020 · 5 shares · 410 followers View post →
Lamorna Nutrition & Fitness
@_Lamorna · X

RT @pronutritionist: Both omega-3 and 6 fatty acids have have very meager effects on inflammation in Crohn’s disease and ulcerative colitis…

Oct 22, 2020 · 5 shares · 415 followers View post →
Jorge Ruiz-Carrascal
@Elorges · X

RT @pronutritionist: Both omega-3 and 6 fatty acids have have very meager effects on inflammation in Crohn’s disease and ulcerative colitis…

Oct 22, 2020 · 5 shares · 1,175 followers View post →
Samuel Durán Agüero
@SamuelNutriChil · X

RT @pronutritionist: Both omega-3 and 6 fatty acids have have very meager effects on inflammation in Crohn’s disease and ulcerative colitis…

Oct 22, 2020 · 5 shares · 3,093 followers View post →
Reijo Laatikainen
@Reijo_RD_FIN · X

Both omega-3 and 6 fatty acids have have very meager effects on inflammation in Crohn’s disease and ulcerative colitis. Meta-analysis of RCTs. Do not put your money on fish oil. No reason to avoid omega-6 FAs either in context of IBD https://t.co/7tSbiejyIo

Oct 22, 2020 · 23 likes · 5 shares · 4,611 followers View post →