J Intern Med February 2021 PMID 33107078

Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study.

S van Oort, J W J Beulens, A J van Ballegooijen, S Burgess, S C Larsson

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Mentions

Peak: 25 in Oct 2020

across 4 sources since Oct 2020

Extended reach

349,630

potential audience

Total likes

2,385

Video views

72,159

Mentions per month

Oct 2020 – Jul 2025

Where it's discussed

X / Twitter40 posts
Facebook4 posts
YouTube2 videos
Reddit2 posts

AI synopsis

What people are saying

Several discussions exemplify in-depth engagement, referencing key risk factors such as LDL cholesterol and BMI, and emphasizing the causal relationships found in the study. Words like 'causally associated' and calls for prevention reflect both interest and recognition of the study’s significance, although the tone remains more informational than transformational.

AgreementModerate agreement

Most discussions acknowledge the study’s findings, with many agreeing that modifying cardiovascular risk factors can influence longevity, as seen in posts highlighting the causal links between factors like high LDL, BMI, and smoking with reduced lifespan.

InterestHigh interest

Posts demonstrate high curiosity, with several posts emphasizing the importance of lifestyle changes and the relevance of the study's findings for health, using phrases like 'good study' and 'new article!'.

EngagementHigh engagement

Many posts delve into the implications of the research, citing specific risk factors and discussing prevention strategies, showing deep engagement with the material.

ImpactModerate impact

While some discussions touch on the potential influence on public health, the overall tone suggests moderate perceived impact, with mentions of prevention and lifestyle changes rather than broad societal change.

Abstract in brief

This study uses Mendelian randomization to explore whether lifestyle and health factors like blood pressure, cholesterol, diabetes, smoking, and education directly influence longevity beyond age 90, finding some factors like genetic liability to Type 2 diabetes, blood pressure, BMI, LDL cholesterol, and smoking decrease the chances of living longer.
Conversely, higher genetically predicted HDL cholesterol and education levels are associated with increased likelihood of reaching advanced ages, suggesting they are beneficial for longevity.
The results indicate that most modifiable risk factors in the Lifes Simple 7 are causally linked to longer life, implying that changing these factors through prevention strategies could improve health outcomes and lifespan.

Read the full abstract

All mentions

Foods and Lifestyle Factors That Extend Healthspan and Longevity

These foods have been shown scientifically to combat aging and prolong life, emphasizing the impact of nutrition and lifestyle on longevity beyond age 90, as supported by recent research on risk factors like blood…

Nutrition Made Simple! · Jul 31, 2025 43,851 views

Genetic and Lifestyle Factors Influencing Longevity Studies

Nutrition Made Simple! · Dec 7, 2020 28,308 views

Chao Wang

@excel_wang · X

For a good study on life style see https://t.co/ciglo0mWvf https://t.co/GgNERUH5Jk

Feb 23, 2023 · 1 like · 1,564 followers View post →

Bhopender Thakur

@TheBhupiThakur · X

RT @AviBittMD: Mendelian randomization on factors that decrease longevity (ORs lower than 1 mean more risk of death, above 1 mean lower ris…

Apr 20, 2021 · 5 shares · 1,368 followers View post →

Dra Malu

@DraMaluvp · X

Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study https://t.co/PaU6QQg78s

Apr 19, 2021 · 1 followers View post →

UniversalMedia

@nivelfirst · X

Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study - Oort - - Journal of Internal Medicine - Wiley Online Library - https://t.co/FC9ex7lfaL

Dec 30, 2020 · 376 followers View post →

Jose Luis Vazquez

@UniversalJLuis · X

Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study - Oort - - Journal of Internal Medicine - Wiley Online Library - https://t.co/0KsI8QXRX0

Dec 30, 2020 · 592 followers View post →

Jose Augusto

@cosmos_augusto · X

Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study - Oort - - Journal of Internal Medicine - Wiley Online Library - https://t.co/2UQovEiu8d

Dec 30, 2020 · 2,053 followers View post →

Agingdoc

@agingdoc1 · X

Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study https://t.co/KRUjfI79ez

Dec 27, 2020 · 1 like · 41,930 followers View post →

Remko Klap

@RemkoKlap · X

RT @jaapseidell: Klassieke risicofactoren (zoals hoog LDL, laag HDL, BMI, hypertensie) causaal geassocieerd met lagere levensverwachting.…

Dec 14, 2020 · 2 shares · 111 followers View post →

De OntZorger3

@DeOntzorger3 · X

RT @jaapseidell: Klassieke risicofactoren (zoals hoog LDL, laag HDL, BMI, hypertensie) causaal geassocieerd met lagere levensverwachting.…

Dec 14, 2020 · 2 shares · 1,063 followers View post →

jacob seidell

@jaapseidell · X

Dec 14, 2020 · 3 likes · 2 shares · 11,223 followers View post →

Pablo Arrona

@PabloArrNutSci · X

RT @AviBittMD: Mendelian randomization on factors that decrease longevity (ORs lower than 1 mean more risk of death, above 1 mean lower ris…

Dec 13, 2020 · 5 shares · 249 followers View post →

Stephen Ellis

@stephenellis24 · X

RT @AviBittMD: Mendelian randomization on factors that decrease longevity (ORs lower than 1 mean more risk of death, above 1 mean lower ris…

Dec 13, 2020 · 5 shares · 77 followers View post →

Gil Carvalho MD PhD

@NutritionMadeS3 · X

RT @AviBittMD: Mendelian randomization on factors that decrease longevity (ORs lower than 1 mean more risk of death, above 1 mean lower ris…

Dec 13, 2020 · 5 shares · 27,945 followers View post →

Kros

@krosenque · X

RT @AviBittMD: Mendelian randomization on factors that decrease longevity (ORs lower than 1 mean more risk of death, above 1 mean lower ris…

Dec 13, 2020 · 5 shares · 721 followers View post →

Carel-Peter van Erpecum

@erpecum · X

RT @JInternMed: New article! Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study…

Nov 2, 2020 · 2 shares · 210 followers View post →

IberianCitizen

@IberianCitizen · X

RT @agingdoc1: Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study. https://t.co…

Oct 29, 2020 · 1 share · 12,909 followers View post →

laili

@laili_lai · X

RT @whsource: Mendelian randomization study: To live a long time, avoid diabetes, high blood pressure, obesity, smoking, and high LDL-chole…

Oct 28, 2020 · 9 shares · 68 followers View post →

Agingdoc

@agingdoc1 · X

Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study. https://t.co/R6H81uUmZf

Oct 28, 2020 · 4 likes · 1 share · 41,930 followers View post →

Brent Boswell

@BrentEBoswell · X

RT @whsource: Mendelian randomization study: To live a long time, avoid diabetes, high blood pressure, obesity, smoking, and high LDL-chole…

Oct 28, 2020 · 9 shares · 27 followers View post →

Joaquín San José

@jsanjosea · X

RT @DanielBerglind: MR study: Several modifiable risk factors (more prevention needed) for cardiovascular disease are causally related to l…

Oct 28, 2020 · 1 share · 408 followers View post →

Topher Hübel

@topherhuebel · X

RT @whsource: Mendelian randomization study: To live a long time, avoid diabetes, high blood pressure, obesity, smoking, and high LDL-chole…

Oct 28, 2020 · 9 shares · 1,668 followers View post →

Sophia Koltavary

@holypaprika23 · X

RT @whsource: Mendelian randomization study: To live a long time, avoid diabetes, high blood pressure, obesity, smoking, and high LDL-chole…

Oct 28, 2020 · 9 shares · 216 followers View post →

Uku Vainik

@ukuv · X

RT @whsource: Mendelian randomization study: To live a long time, avoid diabetes, high blood pressure, obesity, smoking, and high LDL-chole…

Oct 28, 2020 · 9 shares · 1,127 followers View post →

Lucia Ruggiero EALR

@luciaruggiero · X

RT @Mendelian_lit: Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study. https://…

Oct 28, 2020 · 5 shares · 1,033 followers View post →

Equity and Health

@equityhealthdev · X

RT @Mendelian_lit: Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study. https://…

Oct 28, 2020 · 5 shares · 3,464 followers View post →

Culture of Health Eq

@CofHEQ · X

RT @Mendelian_lit: Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study. https://…

Oct 28, 2020 · 5 shares · 1,096 followers View post →

Isaac Ddumba

@ddumba_isaac · X

RT @Mendelian_lit: Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study. https://…

Oct 28, 2020 · 5 shares · 1,126 followers View post →

Global Health Observ

@GlobalPHObserv · X

RT @Mendelian_lit: Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study. https://…

Oct 28, 2020 · 5 shares · 6,553 followers View post →

MR_lit

@Mendelian_lit · X

Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study. https://t.co/KgSPkcPk4T

Oct 28, 2020 · 2 likes · 5 shares · 1,836 followers View post →

ENDALA klinika zdraví

@endalaclinic · X

Oct 28, 2020 · 251 followers View post →

Harmless Frog

@FrogHarmless · X

RT @whsource: Mendelian randomization study: To live a long time, avoid diabetes, high blood pressure, obesity, smoking, and high LDL-chole…

Oct 28, 2020 · 9 shares · 503 followers View post →

Daniel Berglind, PhD

@DanielBerglind · X

MR study: Several modifiable risk factors (more prevention needed) for cardiovascular disease are causally related to longevity: https://t.co/nV43H5GJfF

Oct 28, 2020 · 4 likes · 1 share · 7,770 followers View post →

Mary Lewis

@mem_lewis · X

RT @whsource: Mendelian randomization study: To live a long time, avoid diabetes, high blood pressure, obesity, smoking, and high LDL-chole…

Oct 27, 2020 · 9 shares · 1,437 followers View post →

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@RojoRurba002 · X

RT @drjkahn: Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study - van Oort - -…

Oct 27, 2020 · 1 share · 15,116 followers View post →

Joel "Heart Prevention" Kahn MD, FACC

@drjkahn · X

Oct 27, 2020 · 3 likes · 1 share · 32,255 followers View post →

KayB

@1_Lovelife · X

RT @whsource: Mendelian randomization study: To live a long time, avoid diabetes, high blood pressure, obesity, smoking, and high LDL-chole…

Oct 27, 2020 · 9 shares · 5,829 followers View post →

Mario García Martínez-Gómez, BSc.

@Mariogomecete · X

RT @whsource: Mendelian randomization study: To live a long time, avoid diabetes, high blood pressure, obesity, smoking, and high LDL-chole…

Oct 27, 2020 · 9 shares · 155 followers View post →

Stephan J. Guyenet

@sguyenet · X

Oct 27, 2020 · 64 likes · 9 shares · 48,957 followers View post →

Jeffery Nutrition

@JefferyNutr · X

RT @JInternMed: New article! Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study…

Oct 27, 2020 · 2 shares · 280 followers View post →

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@JInternMed · X

Oct 27, 2020 · 4 likes · 2 shares · 1,648 followers View post →

Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Foods and Lifestyle Factors That Extend Healthspan and Longevity

Genetic and Lifestyle Factors Influencing Longevity Studies