Sci Transl Med October 2020 PMID 33115951

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice.

Shahanshah Khan, Sumyya Waliullah, Victoria Godfrey, Md Abdul Wadud Khan, Rajalaksmy A Ramachandran, Brandi L Cantarel, Cassie Behrendt, Lan Peng, Lora V Hooper, Hasan Zaki

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Mentions

102
Peak: 12 in Oct 2020
across 6 sources since Oct 2020

Extended reach

499,510
potential audience

Total likes

7,049

Video views

356,981

Mentions per month

Oct 2020 – Mar 2024

Where it's discussed

  • News57 articles
  • X / Twitter29 posts
  • Blogs8 articles
  • Reddit4 posts
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

Several discussions emphasize the importance of gut microbiome alterations caused by dietary sugars, with phrases like 'damage the gut's mucus layer' and 'exacerbates colon inflammation' indicating strong agreement and perceived relevance. The tone is both scientific and enthusiastic, demonstrating deep engagement and acknowledgment of potential health impacts.

AgreementStrong agreement

Many discussions explicitly support the findings, citing the role of sugars in damaging gut barriers and exacerbating colitis, demonstrating high consensus.

InterestHigh interest

Postings highlight ongoing research and potential health implications, indicating high engagement and curiosity about the topic.

EngagementHigh engagement

The discussions include references to specific bacteria implicated, mentions of researchers, and vocabulary like 'fascinating' and 'excited', reflecting deep interest.

ImpactHigh impact

Repeated emphasis on understanding gut health and potential dietary changes shows the discussions recognize significant implications for nutrition and medicine.

Abstract in brief

  • Simple sugars like glucose and fructose can worsen colitis (gut inflammation) in mice by changing the gut's microbial community.
  • High sugar diets increase certain bacteria that break down mucus in the gut, leading to the erosion of the protective mucus layer and making the gut more vulnerable to inflammation.
  • The role of microbiota (gut bacteria) is key; when antibiotics are used or mice are germfree, sugars do not worsen colitis, indicating that sugars influence disease development mainly through altering gut bacteria.]

Top posts

Most liked on X and Bluesky
Joy Y. Erdile (Kiddie), MSc, RD
@jyerdile · X

@Healthonics @joelsprechman @UAlbertaGI @ADRaPInitiative @GutMicrobiotaWW @BCCHresearch @DrSonyaJensenND @LJNutrition @MikeMutzel @StrategicHS Researchers found more of the bacteria that damage the gut's protective mucus layer in mice fed high sugar diets. Khan et al. Science Translational Medicine, 2020; 12 (567): eaay6218 DOI: 10.1126/scitranslmed.aay6218

Nov 22, 2020 · 5 likes · 8,576 followers View post →
SSAT
@SSATNews · X

A fascinating frontier linking the microbiome with colitis: Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice. @ScienceTM @DrJamesYoo @BWHSurgMetab https://t.co/oDNFmuCloK

Dec 11, 2020 · 5 likes · 2 shares · 7,615 followers View post →
Agingdoc
@agingdoc1 · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/xYEDuXuMlL “The effect was mediated by alteration of gut microbiota, with an ⬆️ of mucolytic bacteria that facilitated gut mucus barrier degradation” @foundmyfitness @HealthyFellow

Nov 17, 2020 · 4 likes · 1 share · 41,445 followers View post →
Agingdoc
@agingdoc1 · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/xYEDuXuMlL "A diet high in simple sugars aggravated colitis in mouse models when administered before or after colitis induction..."

Oct 30, 2020 · 3 likes · 41,445 followers View post →
Bernat Olle
@bernatolle · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/fdLTs3Aksh

Oct 28, 2020 · 2 likes · 4,436 followers View post →
ZARDyureruomoi ☘
@ZARDyureruomoi · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/pTerIN2yih

Dec 9, 2020 · 2 likes · 1 share · 1,153 followers View post →

All mentions

Mathew Posner
@MathewPosner · X

https://t.co/qgMqFnkWSP

Oct 17, 2022 · 43 followers View post →
Gabe
@GabrielTao3 · X

https://t.co/AWXdlma5cZ

Jan 11, 2022 · 58 followers View post →
Alessandra Frau
@bioale1 · X

https://t.co/f9CBNekRTA

Nov 10, 2021 · 59 followers View post →
Linda Tutty
@LindaTutty · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/bqDSZ09IUD

Mar 13, 2021 · 1 like · 731 followers View post →
Microbes-to-Biomes
@BerkeleyLab_M2B · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/bEyTJG5Wdb

Jan 10, 2021 · 544 followers View post →
Maria Altieri
@altierim1 · X

RT @SSATNews: A fascinating frontier linking the microbiome with colitis: Dietary simple sugars alter microbial ecology in the gut and prom…

Dec 11, 2020 · 2 shares · 1,952 followers View post →
Laboratory for Surgical and Metabolic Research
@BWHSurgMetab · X

RT @SSATNews: A fascinating frontier linking the microbiome with colitis: Dietary simple sugars alter microbial ecology in the gut and prom…

Dec 11, 2020 · 2 shares · 232 followers View post →
SSAT
@SSATNews · X

A fascinating frontier linking the microbiome with colitis: Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice. @ScienceTM @DrJamesYoo @BWHSurgMetab https://t.co/oDNFmuCloK

Dec 11, 2020 · 5 likes · 2 shares · 7,615 followers View post →
ZARDyureruomoi ☘
@ZARDyureruomoi · X

RT @ZARDyureruomoi: Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/pTerIN2yih

Dec 9, 2020 · 1 share · 1,153 followers View post →
ZARDyureruomoi ☘
@ZARDyureruomoi · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/pTerIN2yih

Dec 9, 2020 · 2 likes · 1 share · 1,153 followers View post →
Joy Y. Erdile (Kiddie), MSc, RD
@jyerdile · X

@Healthonics @joelsprechman @UAlbertaGI @ADRaPInitiative @GutMicrobiotaWW @BCCHresearch @DrSonyaJensenND @LJNutrition @MikeMutzel @StrategicHS Researchers found more of the bacteria that damage the gut's protective mucus layer in mice fed high sugar diets. Khan et al. Science Translational Medicine, 2020; 12 (567): eaay6218 DOI: 10.1126/scitranslmed.aay6218

Nov 22, 2020 · 5 likes · 8,576 followers View post →
J P Fanton
@HealthyFellow · X

RT @agingdoc1: Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/xYEDuXuMlL “The effect w…

Nov 17, 2020 · 1 share · 26,023 followers View post →
Agingdoc
@agingdoc1 · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/xYEDuXuMlL “The effect was mediated by alteration of gut microbiota, with an ⬆️ of mucolytic bacteria that facilitated gut mucus barrier degradation” @foundmyfitness @HealthyFellow

Nov 17, 2020 · 4 likes · 1 share · 41,445 followers View post →
Miguel Ángel Sogorb
@MASogorb · X

Dieta rica en azúcar y riesgo de daños intestinales https://t.co/PvRw0NKK82 Más información: Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/Vx7uEGNlzP

Nov 7, 2020 · 158 followers View post →
Casey Hoffman
@Casey_Scientist · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/YinCgBl9xM

Nov 5, 2020 · 1 like · 768 followers View post →
Annikki Aro
@AnnikkiAro · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/p3jInZLDdI

Nov 4, 2020 · 1 like · 486 followers View post →
Hot Science Balloon
@hotsciballoon · X

Nutshell #137: Chronic glucose intake (e.g. Western diet) induces gut microbiome changes and exacerbates colon inflammation. From @UTSWNews in @ScienceTM https://t.co/OMngLsPYEd

Nov 2, 2020 · 1 like · 99 followers View post →
Shirley Smufer
@drssmufer · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/GPGhKssDzo

Oct 31, 2020 · 322 followers View post →
Linda Tutty
@LindaTutty · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/bqDSZ0rjMb

Oct 31, 2020 · 731 followers View post →
Agingdoc
@agingdoc1 · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/xYEDuXuMlL "A diet high in simple sugars aggravated colitis in mouse models when administered before or after colitis induction..."

Oct 30, 2020 · 3 likes · 41,445 followers View post →
Wisam Saleem
@WisamTariq · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/GJ2XLo4B5u

Oct 30, 2020 · 117 followers View post →
Alen Juginović, M.D.
@AlenJuginovic · X

Chronic #glucose intake (e.g. Western #diet) induces gut #microbiome changes & exacerbates #colon #inflammation. From @utswnews in @sciencetm. Article: https://t.co/GHFUUV7AbA #food #sugar #nutrition #medicine #research #science #healthcare #health #nutrition #food #nutrition

Oct 30, 2020 · 423 followers View post →
Dr. Bill Miller
@BillMillerMD · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice | Science Translational Medicine https://t.co/eehfkRPN3d

Oct 30, 2020 · 1 like · 2,424 followers View post →
Symbiosis papers
@Symbiosispapers · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice. https://t.co/68aNkSsEIQ

Oct 30, 2020 · 1,113 followers View post →
Hasan Zaki
@hasanzaki02 · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/NVmqJffudp We are very excited to see our work published in Science Translational Medicine. I thank to all my lab members and co-authors for their great effort and support.

Oct 29, 2020 · 25 followers View post →
Shruti Nagaraja
@ShrutiN4 · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice | Science Translational Medicine ⁦ https://t.co/EtUJV0BO4S

Oct 29, 2020 · 1 like · 289 followers View post →
Wenke Feng
@wenke_feng · X

SUGAR HIJACKS AN ESSENTIAL PART OF HEALTH THROUGH YOUR GUT BUGS. Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/x9lyHoNOGe

Oct 29, 2020 · 81 followers View post →
Shahanshah Khan
@DrShahanshah · X

I am pleased to share with you that our study published in today`s Science Translational Medicine. Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/xo1typ4GIf

Oct 28, 2020 · 1 like · 9 followers View post →
Bernat Olle
@bernatolle · X

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice https://t.co/fdLTs3Aksh

Oct 28, 2020 · 2 likes · 4,436 followers View post →