PLoS One December 2020 PMID 33152050

Commonly used clinical chemistry tests as mortality predictors: Results from two large cohort studies.

Lars Lind, Daniela Zanetti, Marieann Högman, Lars Sundman, Erik Ingelsson

Mentions

3
Peak: 1 in Nov 2023
across 2 sources since Nov 2023

Extended reach

22,689
potential audience

Total likes

123

Video views

3,236

Mentions per month

Nov 2023 – May 2024

Where it's discussed

  • X / Twitter2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions highlight curiosity about how specific blood markers like liver enzymes relate to mortality risk, with users referencing particular thresholds and comparisons to different populations. The tone remains analytical, focusing on understanding variability and challenges in interpreting these biomarkers, which indicates a moderate level of interest and engagement without a definitive consensus on the article's overall impact.

AgreementNeither agree nor disagree

The discussions show mixed opinions about the interpretation of the findings, with some posts accepting the results and others expressing uncertainty.

InterestModerate interest

Participants demonstrate a curiosity about specific biomarkers and their relationship to mortality, indicating at least moderate interest.

EngagementModerate engagement

The conversations involve sharing additional questions and methodological details, reflecting some direct engagement with the material.

ImpactNeutral impact

While the discussions acknowledge potential clinical implications, they do not strongly emphasize immediate or transformative impacts.

Abstract in brief

  • The study analyzed how 11 common blood tests relate to the risk of death over long-term follow-up in two large population cohorts, finding that most tests are associated with mortality.
  • Both linear and U-shaped relationships were observed, meaning some test results increase risk while others only pose a risk outside of normal ranges, suggesting that defining "normal" based on mortality risk could improve prediction.
  • Incorporating these biomarkers into existing risk models slightly improved the ability to predict mortality, indicating their potential value in clinical risk assessment beyond traditional factors.]

Top posts

Most liked on X and Bluesky
Mike Lustgarten, PhD
@mike_lustgarten · X

@neilquinn Yep-around 5 is associated with reduced ACM risk: https://t.co/Cp5hGcxkjS Also avoiding an age-related increase

Mar 1, 2024 · 1 like · 9,727 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

@BowTiedGrizzlyB > 1.4 mg/dL (24 umol/L) is associated with an increased all-cause mortality risk in UK Biobank (https://t.co/Cp5hGcxkjS) but not in the X69 study (same link), so it's tough to say... What are your other liver markers, including albumin, alkaline phosphatase, AST, ALT, GGT?

Nov 11, 2023 · 9,727 followers View post →

All mentions

Mike Lustgarten, PhD
@mike_lustgarten · X

@neilquinn Yep-around 5 is associated with reduced ACM risk: https://t.co/Cp5hGcxkjS Also avoiding an age-related increase

Mar 1, 2024 · 1 like · 9,727 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

@BowTiedGrizzlyB > 1.4 mg/dL (24 umol/L) is associated with an increased all-cause mortality risk in UK Biobank (https://t.co/Cp5hGcxkjS) but not in the X69 study (same link), so it's tough to say... What are your other liver markers, including albumin, alkaline phosphatase, AST, ALT, GGT?

Nov 11, 2023 · 9,727 followers View post →