May 2021 PMID 33179374

Abnormal thyroid function is common in takotsubo syndrome and depends on two distinct mechanisms: results of a multicentre observational study.

A Aweimer, I El-Battrawy, I Akin, M Borggrefe, A Mügge, P C Patsalis, A Urban, M Kummer, S Vasileva, A Stachon, S Hering, J W Dietrich

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Mentions

51
Peak: 24 in Nov 2020
across 5 sources since Nov 2020

Extended reach

861,436
potential audience

Total likes

127

Video views

2,255

Mentions per month

Nov 2020 – May 2024

Where it's discussed

  • X / Twitter39 posts
  • News8 articles
  • Facebook2 posts
  • Bluesky1 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions reflect high engagement through references to detailed mechanisms like elevated FT4 levels and dual etiology and emphasize the importance of understanding thyroid function in TTS, using technical language and citing scientific methods such as AI clustering for deeper insights.

AgreementStrong agreement

Most discussions support the article's conclusion that abnormal thyroid function is significant in takotsubo syndrome and agree with its mechanisms.

InterestHigh interest

Discussions show high interest, with references to related concepts like the #thyrocardiac axis, allostasis, and advanced analysis methods such as AI and machine learning.

EngagementHigh engagement

Many posts delve into detailed explanations, cite multiple studies, and share summaries, indicating deep engagement.

ImpactHigh impact

Posts highlight that thyroid function abnormalities could influence prevention and treatment strategies, emphasizing their potential impact on clinical practice.

Abstract in brief

  • The study found that abnormal thyroid function, especially elevated free T4 levels and hyperthyroidism, is common in patients with takotsubo syndrome (TTS), with some developing it during hospitalization, indicating a possible stress-related endocrine response.
  • Patients with TTS showed significantly higher FT4 levels compared to those with acute coronary syndrome (ACS) and healthy controls, and a subset had overt or subclinical thyrotoxicosis, suggesting a link between thyroid hormone dysregulation and TTS.
  • The research suggests that thyroid function abnormalities, including an elevated set point of thyroid homeostasis, might play a role in the development or progression of TTS, making thyroid health a potential target for treatment or prevention strategies.

Top posts

Most liked on X and Bluesky
Johannes W. Dietrich
@drjwdietrich · X

@HeedLab This is the graphical abstract of one of our papers. We tried to not only repeat the abstract in words but to make a synthesis of different partial findings. And, of course, the artist working for the journal did a great job. https://t.co/ijRxgLGxKh https://t.co/bx3uoRJjK1

Oct 9, 2021 · 18 likes · 1,143 followers View post →
Dr. med. Levin Kaan B.
@kaan_levin · X

#Takotsubo kardiyomiyopatisi olan ağırlıklı kadın hastaların çoğunda, kalp kasının stres hormonlarına duyarlılığını artırabilecek aşırı aktif bir tiroid bezi vardır. https://t.co/4zo1ZCow3d

Jun 21, 2021 · 12 likes · 11,759 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

A lay summary about our recent study on #thyroid #homeostasis, #allostasis and #dyshomeostasis in #Takotsubo syndrome (TTS) is available at Scibey. Thyroid function may be a worthwhile target in prevention and management of TTS. https://t.co/DfvqNTn82e https://t.co/SwoMIACMlZ

Jan 18, 2021 · 11 likes · 7 shares · 1,143 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

Our next paper: Abnormal #thyroid function is common in #takotsubo syndrome and depends on two distinct mechanisms: results of a multicentre observational study https://t.co/ww2kTVrdgp

Nov 12, 2020 · 11 likes · 4 shares · 1,143 followers View post →
Johannes W. Dietrich
@drjwdietrich.bsky.social · Bluesky

Thanks, this is interesting and important. Recently, many other circuits have been discovered, e.g. the #thyrocardiac axis. pubmed.ncbi.nlm.nih.gov/33179374/ doi.org/10.1111/joim...

May 11, 2024 · 8 likes · 1 share View post →
Dr. med. Levin Kaan B.
@kaan_levin · X

Sonuçlar daha sonraki çalışmalarda doğrulanırsa, tiroid bezinin bozuklukları tüm Takotsubo kardiyomiyopatilerinin 2/3'ünden en azından kısmen sorumlu olabilir. https://t.co/4zo1ZCow3d https://t.co/NeQ7WOr5Kq

Jun 21, 2021 · 6 likes · 11,759 followers View post →

All mentions

Johannes W. Dietrich
@drjwdietrich.bsky.social · Bluesky

Thanks, this is interesting and important. Recently, many other circuits have been discovered, e.g. the #thyrocardiac axis. pubmed.ncbi.nlm.nih.gov/33179374/ doi.org/10.1111/joim...

May 11, 2024 · 8 likes · 1 share View post →
Johannes W. Dietrich
@drjwdietrich · X

@HDstabil TSH kann wegen einer Hypothyreose erhöht sein. Es kann aber auch hoch sein, weil der Sollwert des Regelkreises erhöht ist, bei psychosozialem Stress und Typ-2-allostatischer Last. Im Falle eines Delirs ist eine erhöhte TSH-Konzentration nicht ungewöhnlich. https://t.co/ijRxgLGxKh https://t.co/oqMgZGVxwh

Mar 8, 2023 · 2 likes · 1,143 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

@HeedLab This is the graphical abstract of one of our papers. We tried to not only repeat the abstract in words but to make a synthesis of different partial findings. And, of course, the artist working for the journal did a great job. https://t.co/ijRxgLGxKh https://t.co/bx3uoRJjK1

Oct 9, 2021 · 18 likes · 1,143 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

@FionaPWME @dr_kevinlee This also applies to type 2 #thyroid allostasis, which increases the risk for #takotsubo syndrome (stress cardiomyopathy) and... https://t.co/ijRxgLGxKh

Aug 8, 2021 · 1 like · 1,143 followers View post →
Dr. med. Levin Kaan B.
@kaan_levin · X

Sonuçlar daha sonraki çalışmalarda doğrulanırsa, tiroid bezinin bozuklukları tüm Takotsubo kardiyomiyopatilerinin 2/3'ünden en azından kısmen sorumlu olabilir. https://t.co/4zo1ZCow3d https://t.co/NeQ7WOr5Kq

Jun 21, 2021 · 6 likes · 11,759 followers View post →
Dr. med. Levin Kaan B.
@kaan_levin · X

#Takotsubo kardiyomiyopatisi olan ağırlıklı kadın hastaların çoğunda, kalp kasının stres hormonlarına duyarlılığını artırabilecek aşırı aktif bir tiroid bezi vardır. https://t.co/4zo1ZCow3d

Jun 21, 2021 · 12 likes · 11,759 followers View post →
Marïanne K
@MarianneKnen · X

RT @drjwdietrich: A lay summary about our recent study on #thyroid #homeostasis, #allostasis and #dyshomeostasis in #Takotsubo syndrome (TT…

Jan 19, 2021 · 7 shares · 488 followers View post →
Dr Kevin Lee
@dr_kevinlee · X

RT @drjwdietrich: A lay summary about our recent study on #thyroid #homeostasis, #allostasis and #dyshomeostasis in #Takotsubo syndrome (TT…

Jan 19, 2021 · 7 shares · 5,438 followers View post →
susi
@susi38532167 · X

RT @drjwdietrich: A lay summary about our recent study on #thyroid #homeostasis, #allostasis and #dyshomeostasis in #Takotsubo syndrome (TT…

Jan 18, 2021 · 7 shares · 450 followers View post →
Assem Aweimer
@DrAweimer · X

RT @drjwdietrich: A lay summary about our recent study on #thyroid #homeostasis, #allostasis and #dyshomeostasis in #Takotsubo syndrome (TT…

Jan 18, 2021 · 7 shares · 60 followers View post →
Linda Sanday
@SandayLinda · X

RT @drjwdietrich: A lay summary about our recent study on #thyroid #homeostasis, #allostasis and #dyshomeostasis in #Takotsubo syndrome (TT…

Jan 18, 2021 · 7 shares · 109 followers View post →
Vociferous Eleanor Give me #Liothyronine on NHS
@ThyroidAction · X

RT @drjwdietrich: A lay summary about our recent study on #thyroid #homeostasis, #allostasis and #dyshomeostasis in #Takotsubo syndrome (TT…

Jan 18, 2021 · 7 shares · 808 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

A lay summary about our recent study on #thyroid #homeostasis, #allostasis and #dyshomeostasis in #Takotsubo syndrome (TTS) is available at Scibey. Thyroid function may be a worthwhile target in prevention and management of TTS. https://t.co/DfvqNTn82e https://t.co/SwoMIACMlZ

Jan 18, 2021 · 11 likes · 7 shares · 1,143 followers View post →
Patrick Mueller, MD
@dr_pmueller · X

RT @drjwdietrich: @evasophiee1 @chatzitomap @HoermannRudolf Thanks. We are continuing this story. See our more recent papers on thyro-cardi…

Dec 18, 2020 · 2 shares · 1,417 followers View post →
Assem Aweimer
@DrAweimer · X

RT @drjwdietrich: @evasophiee1 @chatzitomap @HoermannRudolf Thanks. We are continuing this story. See our more recent papers on thyro-cardi…

Dec 18, 2020 · 2 shares · 60 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

@evasophiee1 @chatzitomap @HoermannRudolf Thanks. We are continuing this story. See our more recent papers on thyro-cardiac interaction, confirming our previous conclusions with additional evidence. @dr_pmueller @AssemAweimer https://t.co/1YhaGJBH7v https://t.co/ijRxgLGxKh https://t.co/jv4qIgp2je

Dec 18, 2020 · 4 likes · 2 shares · 1,143 followers View post →
JIM - Journal of Internal Medicine
@JInternMed · X

RT @JInternMed: New research: Abnormal thyroid function is common in #takotsubo syndrome and depends on two distinct mechanisms: results of…

Nov 24, 2020 · 4 shares · 1,643 followers View post →
U J P
@UJPCurran · X

RT @SPINATeam: #SPINA_GT is significantly elevated in #stress #cardiomyopathy (#takotsubo syndrome). https://t.co/V8anvhaSlj https://t.co/6…

Nov 20, 2020 · 3 shares · 87 followers View post →
AI Bot
@Artificialbra1n · X

RT @drjwdietrich: With artificial intelligence / machine learning we identified two clusters of #thyroid function in #TTS and three cluster…

Nov 19, 2020 · 6 shares · 1,956 followers View post →
Machine Learning Bot
@ML_Tweet_Bot · X

RT @drjwdietrich: With artificial intelligence / machine learning we identified two clusters of #thyroid function in #TTS and three cluster…

Nov 18, 2020 · 6 shares · 10,144 followers View post →
AI Bot
@Artificialbra1n · X

RT @drjwdietrich: With artificial intelligence / machine learning we identified two clusters of #thyroid function in #TTS and three cluster…

Nov 18, 2020 · 6 shares · 1,956 followers View post →
Thread Reader App
@threadreaderapp · X

@drjwdietrich Bonjour, the unroll you asked for: @drjwdietrich: Our next paper: Abnormal #thyroid function is common in #takotsubo syndrome and depends on two distinct… https://t.co/hEZcbGQWQM See you soon.

Nov 18, 2020 · 783,548 followers View post →
Linda Sanday
@SandayLinda · X

RT @SPINATeam: #SPINA_GT is significantly elevated in #stress #cardiomyopathy (#takotsubo syndrome). https://t.co/V8anvhaSlj https://t.co/6…

Nov 17, 2020 · 3 shares · 109 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

RT @SPINATeam: #SPINA_GT is significantly elevated in #stress #cardiomyopathy (#takotsubo syndrome). https://t.co/V8anvhaSlj https://t.co/6…

Nov 17, 2020 · 3 shares · 1,143 followers View post →
SPINA Team
@SPINATeam · X

#SPINA_GT is significantly elevated in #stress #cardiomyopathy (#takotsubo syndrome). https://t.co/V8anvhaSlj https://t.co/6yxosS7t4t

Nov 17, 2020 · 4 likes · 3 shares · 125 followers View post →
Machine Learning Bot
@ML_Tweet_Bot · X

RT @drjwdietrich: With artificial intelligence / machine learning we identified two clusters of #thyroid function in #TTS and three cluster…

Nov 16, 2020 · 6 shares · 10,144 followers View post →
AI Bot
@Artificialbra1n · X

RT @drjwdietrich: With artificial intelligence / machine learning we identified two clusters of #thyroid function in #TTS and three cluster…

Nov 16, 2020 · 6 shares · 1,956 followers View post →
Assem Aweimer
@DrAweimer · X

RT @drjwdietrich: Our next paper: Abnormal #thyroid function is common in #takotsubo syndrome and depends on two distinct mechanisms: resul…

Nov 14, 2020 · 4 shares · 60 followers View post →
Assem Aweimer
@DrAweimer · X

RT @JInternMed: New research: Abnormal thyroid function is common in #takotsubo syndrome and depends on two distinct mechanisms: results of…

Nov 14, 2020 · 4 shares · 60 followers View post →
SPINA Team
@SPINATeam · X

RT @drjwdietrich: In summary, normal #thyroid function seems to be the exception rather than the rule in #takotsubo syndrome. #Stress #card…

Nov 13, 2020 · 1 share · 125 followers View post →
SPINA Team
@SPINATeam · X

RT @drjwdietrich: With artificial intelligence / machine learning we identified two clusters of #thyroid function in #TTS and three cluster…

Nov 13, 2020 · 6 shares · 125 followers View post →
SPINA Team
@SPINATeam · X

RT @drjwdietrich: #FT4 was elevated or high-normal in #TTS, #SPINA_GT was high in a significant subgroup, #FT3 and #SPINA_GD were relativel…

Nov 13, 2020 · 1 share · 125 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

In summary, normal #thyroid function seems to be the exception rather than the rule in #takotsubo syndrome. #Stress #cardiomyopathy has a dual etiology, an increased set point of thyroid function (stress type, #allostatic load) and increased #SPINA_GT. https://t.co/ijRxgLGxKh https://t.co/H90eiEy5sE

Nov 13, 2020 · 5 likes · 1 share · 1,143 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

#FT4 was elevated or high-normal in #TTS, #SPINA_GT was high in a significant subgroup, #FT3 and #SPINA_GD were relatively low. #TSH and markers for the set point (#TTSI and #TFQI) had a remarkable high dispersion, as demonstrated in binomial testing. https://t.co/uy4wjDNvBR https://t.co/lleK45IMkV

Nov 13, 2020 · 3 likes · 1 share · 1,143 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

From a physiological perspective, the two clusters represent a dual etiology of high or high-normal FT4 in TTS, impending primary #thyrotoxicosis and a high set point of #thyroid #homeostasis, corresponding to type 2 #allostatic load. #Thyroid_Allostasis https://t.co/CJsLn62kfK https://t.co/j4ltzadS4c

Nov 13, 2020 · 2 likes · 1,143 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

With artificial intelligence / machine learning we identified two clusters of #thyroid function in #TTS and three clusters in the whole population. #AI #ML https://t.co/ijRxgLGxKh https://t.co/4jEyg1cMis

Nov 13, 2020 · 2 likes · 6 shares · 1,143 followers View post →
AQUA FONTIS Study
@StudyAqua · X

RT @JInternMed: New research: Abnormal thyroid function is common in #takotsubo syndrome and depends on two distinct mechanisms: results of…

Nov 12, 2020 · 4 shares · 46 followers View post →
JIM - Journal of Internal Medicine
@JInternMed · X

New research: Abnormal thyroid function is common in #takotsubo syndrome and depends on two distinct mechanisms: results of a multicentre observational study. https://t.co/wTahmc4UVH https://t.co/q8JpsM9aBt

Nov 12, 2020 · 5 likes · 4 shares · 1,643 followers View post →
SPINA Team
@SPINATeam · X

RT @drjwdietrich: Our next paper: Abnormal #thyroid function is common in #takotsubo syndrome and depends on two distinct mechanisms: resul…

Nov 12, 2020 · 4 shares · 125 followers View post →
Johannes W. Dietrich
@drjwdietrich · X

Our next paper: Abnormal #thyroid function is common in #takotsubo syndrome and depends on two distinct mechanisms: results of a multicentre observational study https://t.co/ww2kTVrdgp

Nov 12, 2020 · 11 likes · 4 shares · 1,143 followers View post →