Plasma dilution improves cognition and attenuates neuroinflammation in old mice Young blood transfusions are out; diluting old blood is in. Therapeutic plasma exchange is already an FDA approved procedure https://t.co/aafH1CjGdB
Plasma dilution improves cognition and attenuates neuroinflammation in old mice.
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Nov 2020 – Sep 2025Where it's discussed
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X / Twitter68 posts
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News17 articles
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Blogs4 articles
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AI synopsis
What people are saying
The discussions highlight excitement around the findings, with users describing plasma dilution as a potential 'game changer' for cognitive health. For instance, phrases like 'easily achieved by plasma donation' and references to the efficacy of plasma dilution over young blood transfusions indicate a practical and impactful perspective. The tone remains enthusiastic, with many seeking further information and expressing a sense of urgency regarding the research's implications for aging.
Many discussions show a positive outlook on the publication, indicating that the findings are generally welcomed and supported by the community.
Posts reflect a strong curiosity in the implications of plasma dilution, with users eager to explore its effects on cognition and neuroinflammation.
Users delve deeply into the research methods and implications, sharing insights and additional references that enhance the discussion.
The majority believe the publication has significant implications for future studies and therapeutic approaches in aging and cognitive health.
Abstract in brief
- NBE (Neutral Blood Exchange) significantly improves cognitive performance and reduces neuroinflammation in older mice, leading to better brain health.
- The study found that NBE was more effective in enhancing brain rejuvenation than the senolytic drug ABT 263, highlighting that simply reducing senescence isn't enough for cognitive benefits.
- Proteomic analyses indicated that diluting old blood plasma boosts factors that support brain maintenance and repair, thereby promoting overall cognitive function in aging mammals.
Top posts
Most liked on X and Bluesky@Sturgeons_Law @forwardourmotto https://t.co/UbJTM0UGl1 i found it. Young blood doesnt seem to rejuvenate as much as old blood is just full of gunk. They even did a followup! https://t.co/sjB7EQwWsn
Rejuvenation by dilution? In this video i discuss the latest work from the Conboy lab on neutral blood exchange! --> https://t.co/R5Clyt0ZTu #aging #rejuvenation #plasmaexchange #scicomm #AcademicYouTube @WeCreateEdu https://t.co/KvVSdjMQP1
Another phenomenal video from @EleanorSheekey, this time explaining blood plasma dilution. https://t.co/fFDSjPyXFz
Plasma dilution improves cognition and attenuates neuroinflammation in old mice https://t.co/6cOvMFMRZK
https://t.co/F8g3NjVWtK
All mentions
Impact of Plasma Dilution on Cognitive Health in Older Mice
Plasma dilution significantly improves cognitive performance and reduces neuroinflammation in older mice, enhancing brain health. This video explores how Neutral Blood Exchange (NBE) promotes brain maintenance…
Impact of Hyperbaric Oxygen Therapy on Aging and Cognitive Function
In this episode, we explore Hyperbaric Oxygen Therapy's role in telomere length and immunosenescence. Additionally, research reveals that plasma dilution significantly improves cognition and reduces neuroinflammation in…
Understanding Harold Katcher's Plasma Fraction Rejuvenation Findings
In this video, Nina Torres Zanvettor explains Harold Katcher's plasma fraction used to achieve significant advances in mammalian rejuvenation science. This research, examining the effects of young pig plasma on aging…
https://t.co/B9g0dmVtcx #HBOTisthenewtanningsalon #letsgetperky #forever21
Diluting out the senescent components of old blood increases cognitive ability of old animals through stimulation of neurogenesis. https://t.co/RuMFCKZJSs
5/ A Mouse Study on cognition and neuroinflammation. https://t.co/zbgKXSqXUV
@ScottDavidKeefe @siimland Oddly enough... It certainly seems unusual. https://t.co/nhGSYtPJoA
@pieter_mj_j @MitoPsychoBio “Age elevated systemic proteome was restored to youth with maintenance and repair of muscle, liver, and brain, without any added young blood, young plasma, or young factors” - ref; https://t.co/gRHxXJaWAt
@Sturgeons_Law @forwardourmotto https://t.co/UbJTM0UGl1 i found it. Young blood doesnt seem to rejuvenate as much as old blood is just full of gunk. They even did a followup! https://t.co/sjB7EQwWsn
https://t.co/F8g3NjVWtK
@chydorina 1) https://t.co/9HYnzOrjgt 2) https://t.co/XiozoH2dHl
@newscientist # The news spread, but it should be noticed that even a plasma dilution can have similar positive effects: Plasma dilution improves cognition and attenuates neuroinflammation in old mice: https://t.co/ek5gxhzAoD
# The news spread, but it should be noticed that even a plasma dilution can have similar positive effects: Plasma dilution improves cognition and attenuates neuroinflammation in old mice: https://t.co/ek5gxhzAoD https://t.co/H2mZJ9u6kN
RT @YujiMarutani: Watch "Rejuvenation by dilution? (Therapeutic plasma exchange)" on YouTube https://t.co/KtCM5hKJXW
Plasma dilution improves cognition and attenuates neuroinflammation in old mice. https://t.co/ipb7s75xhy
Easily achieved by plasma donation and substitution with NaCl -very intriguing! https://t.co/30mRyAVFOX
@jpsenescence @mlurker444 It works in the sense of reducing senescence (or transferring it) or reducing the hallmarks of aging. It is, however, not really a practical solution. It has similarities to plasma dilution which is more practical and ethical. https://t.co/4jbN0GvUkr
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@kevinnbass Aside from the sm. segment w/ HH & debate whether we benefit w/ lower-end of HCT/HgB range (iron bioacc), in the parabiosis lit there's stronger evidence for plasma dilution of old-factors than for young blood health factors (but both likely). Conboy et al https://t.co/ebtk34r1Sf
RT @bk21kumc: https://t.co/wl0VXX95C9 Geroscience. 2021 Feb;43(1):1-18. doi: 10.1007/s11357-020-00297-8. Epub 2020 Nov 15. Plasma dilutio…
https://t.co/wl0VXX95C9 Geroscience. 2021 Feb;43(1):1-18. doi: 10.1007/s11357-020-00297-8. Epub 2020 Nov 15. Plasma dilution improves cognition and attenuates neuroinflammation in old mice
Blood plasma dilution improves cognition and attenuates neuroinflammation in old mice (2021) via /r/Nootropics https://t.co/kS2UzQHMoU
Watch "Rejuvenation by dilution? (Therapeutic plasma exchange)" on YouTube https://t.co/KtCM5hKJXW
RT @EleanorSheekey: Rejuvenation by dilution? In this video i discuss the latest work from the Conboy lab on neutral blood exchange! --> h…
RT @elidourado: Another phenomenal video from @EleanorSheekey, this time explaining blood plasma dilution. https://t.co/fFDSjPyXFz
RT @EleanorSheekey: Rejuvenation by dilution? In this video i discuss the latest work from the Conboy lab on neutral blood exchange! --> h…
RT @elidourado: Another phenomenal video from @EleanorSheekey, this time explaining blood plasma dilution. https://t.co/fFDSjPyXFz
RT @elidourado: Another phenomenal video from @EleanorSheekey, this time explaining blood plasma dilution. https://t.co/fFDSjPyXFz
RT @EleanorSheekey: Rejuvenation by dilution? In this video i discuss the latest work from the Conboy lab on neutral blood exchange! --> h…
RT @elidourado: Another phenomenal video from @EleanorSheekey, this time explaining blood plasma dilution. https://t.co/fFDSjPyXFz
Another phenomenal video from @EleanorSheekey, this time explaining blood plasma dilution. https://t.co/fFDSjPyXFz
RT @EleanorSheekey: Rejuvenation by dilution? In this video i discuss the latest work from the Conboy lab on neutral blood exchange! --> h…
Rejuvenation by dilution? In this video i discuss the latest work from the Conboy lab on neutral blood exchange! --> https://t.co/R5Clyt0ZTu #aging #rejuvenation #plasmaexchange #scicomm #AcademicYouTube @WeCreateEdu https://t.co/KvVSdjMQP1
1/2 Hi @sbarnettARK - I’ve read a paper from the Conboy couple regarding their longevity research (https://t.co/nEHX72fPne) it seems to me that a breakthrough in this area could pose a significant risk to many of the companies tackling disease which relates to age (ie cancer)
RT @rewireupgrade: Plasma dilution improves cognition and attenuates neuroinflammation in old mice https://t.co/UUaUfCNedo
Plasma dilution improves cognition and attenuates neuroinflammation in old mice https://t.co/UUaUfCNedo
RT @alfredopietraca: A procedure referred to as neutral blood exchange (NBE) resets signaling milieu to a pro-regenerative state through di…
A procedure referred to as neutral blood exchange (NBE) resets signaling milieu to a pro-regenerative state through dilution of old plasma, enhanced the health and repair of the muscle and liver, and promoted better hippocampal neurogenesis. https://t.co/nr9j0tXYGx
@palace Att hälso- och livsförlängningen man sett när man ger ungt blod till åldrade möss mycket väl kan bero på att man spär ut något ohälsosamt i blodplasman snarare än att det unga blodet i sig är bra: https://t.co/OHiL9g0YgN
Simple Plasma dilution improves cognition and attenuates neuroinflammation in old mice https://t.co/FDP0uceLIw
RT @AgingBiology: Plasma dilution improves cognition and attenuates neuroinflammation in old mice https://t.co/6cOvMFMRZK
RT @Mangan150: Plasma dilution improves cognition and attenuates neuroinflammation in old mice Young blood transfusions are out; diluting…
Plasma dilution improves cognition and attenuates neuroinflammation in old mice #science #biology https://t.co/0kixq2a2iw
RT @Mangan150: Plasma dilution improves cognition and attenuates neuroinflammation in old mice Young blood transfusions are out; diluting…
RT @Mangan150: Plasma dilution improves cognition and attenuates neuroinflammation in old mice Young blood transfusions are out; diluting…
RT @Mangan150: Plasma dilution improves cognition and attenuates neuroinflammation in old mice Young blood transfusions are out; diluting…
Think about basic chemistry: things diffuse from higher concentrations to lower. Clean your brain by lowering your plasma concentrations: 1. Drink water. 2. Donate plasma. https://t.co/AuFt8DSpNi
RT @Mangan150: Plasma dilution improves cognition and attenuates neuroinflammation in old mice Young blood transfusions are out; diluting…
RT @Mangan150: Plasma dilution improves cognition and attenuates neuroinflammation in old mice Young blood transfusions are out; diluting…
RT @Mangan150: Plasma dilution improves cognition and attenuates neuroinflammation in old mice Young blood transfusions are out; diluting…
RT @Mangan150: Plasma dilution improves cognition and attenuates neuroinflammation in old mice Young blood transfusions are out; diluting…
Plasma dilution improves cognition and attenuates neuroinflammation in old mice Young blood transfusions are out; diluting old blood is in. Therapeutic plasma exchange is already an FDA approved procedure https://t.co/aafH1CjGdB
Plasma dilution improves cognition and attenuates neuroinflammation in old mice https://t.co/htbRbbkfFK
RT @hkanji: Aging is partially caused by aging factors found in our blood https://t.co/JSbQry36JG
RT @hkanji: Aging is partially caused by aging factors found in our blood https://t.co/JSbQry36JG
Aging is partially caused by aging factors found in our blood https://t.co/JSbQry36JG
"Plasma dilution improves cognition and attenuates neuroinflammation in old mice, with this, heterochronic parabiosis studies seeded the field of systemic aging and rejuvenation." https://t.co/ipb7s74Zs0
https://t.co/bgWNjbTvSs
RT @MariaErmolaev13: Replacing half of old plasma with saline containing 5% albumin recapitulates the rejuvinating effect of the heterochro…
Replacing half of old plasma with saline containing 5% albumin recapitulates the rejuvinating effect of the heterochronic blood transfer? Is it really that simple? https://t.co/aXR4GgZy62
These findings confirm the paradigm of rejuvenation through dilution of age-elevated systemic factors and extrapolate it to brain health and function. https://t.co/ipb7s74Zs0
Plasma dilution improves cognition and attenuates neuroinflammation in old mice https://t.co/6cOvMFMRZK
Plasma dilution improves cognition and attenuates neuroinflammation in old mice. https://t.co/zmH3uDAxPN
Another paper on plasma dilution from the Conboy Lab (which is leading the charge on this line of research). Plasma dilution is more effective for brain rejuvenation than senolytics, suggesting there are age-elevated blood factors beyond the SASP. https://t.co/VWc8jrR2cR
RT @MattYousefzadeh: https://t.co/S7dAgsqasl
https://t.co/S7dAgsqasl
Plasma dilution improves cognition and attenuates neuroinflammation in old mice https://t.co/RdUTVlgJli https://t.co/mWEs2DOWjW
Plasma dilution improves cognition and attenuates neuroinflammation in old mice | SpringerLink https://t.co/nx3Tq2UkTt
Plasma dilution improves cognition and attenuates neuroinflammation in old mice. “Summarily, this work supports the paradigm that diluting and resetting to health and youth systemic signaling milieu promotes the “young” determinants of tissue health” https://t.co/cE1lJXSx3Y
Corrected URL here: https://t.co/cE1lJXSx3Y
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