Autism May 2021 PMID 33213190

Age at autism spectrum disorder diagnosis: A systematic review and meta-analysis from 2012 to 2019.

Maarten van 't Hof, Chanel Tisseur, Ina van Berckelear-Onnes, Annemyn van Nieuwenhuyzen, Amy M Daniels, Mathijs Deen, Hans W Hoek, Wietske A Ester

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Mentions

34
Peak: 10 in Nov 2020
across 2 sources since Nov 2020

Extended reach

114,146
potential audience

Total likes

240

Video views

2,826

Mentions per month

Nov 2020 – Sep 2025

Where it's discussed

  • X / Twitter32 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect a high level of engagement with citations and analysis, such as references to the global average age at diagnosis and variations across studies. The tone varies from supportive agreement to critical questions about methodology and the implications of earlier detection, showing both interest and active participation in understanding the research's significance.

AgreementModerate agreement

Most discussions acknowledge the findings, with some emphasizing the importance of early diagnosis and noting the variability in the data.

InterestHigh interest

Posts show high interest in the subject, referencing specific statistics, methodological concerns, and the implications of the findings for clinical practice.

EngagementModerate engagement

Several posts cite sources, question study details, or comment on aspects like study design and global differences, indicating active engagement.

ImpactModerate impact

While some discussions highlight the relevance of the findings for policy and healthcare, there is a cautious tone about conclusive changes, suggesting a moderate perceived impact.

Abstract in brief

  • This systematic review and meta-analysis, covering studies from 2012 to 2019, found that the current average age at autism spectrum disorder (ASD) diagnosis globally is around 60 months (about 5 years old), with some variation depending on age groups and study specifics.
  • The research highlights that various factors, such as the type of autism, additional diagnoses, and gender, may influence the age at diagnosis, but results are often conflicting or inconclusive.
  • Overall, despite progress in earlier detection, the study emphasizes the need for ongoing efforts to diagnose ASD at younger ages worldwide.]

Top posts

Most liked on X and Bluesky
Vicki Allen Crabb
@crabb_vicki · X

Citations. https://t.co/cK2EFTNdwm https://t.co/EZxxRpnSj6

Aug 3, 2025 · 15 likes · 1 share · 5,543 followers View post →
José Ignacio Leyda
@ignacioleyda · X

Nov 22, 2020 · 10 likes · 3 shares · 8,265 followers View post →
عادل الشمري، BsC, MsC- Clinical Senior A & SLP/RBT
@dradilalshammar · X

"بناء على ٣٥ دراسة بحثية معتمدة في ٣٥ دولة، متوسط عمر التشخيص الرسمي ب التوحد للاطفال هو بعمر خمس سنوات" ⚠️⚠️إلا عندنا، مستعدين (البعض) للتشخيص المؤكد بالتوحد ل طفل بعمر سنه ونص!!⚠️⚠️ ⭕الاسباب كثيرة والخطأ التشخيصي مؤكد!⭕

Sep 24, 2021 · 8 likes · 1 share · 4,260 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@SamathaCook45 @krebiozen @BGLTHMND @troydee @scientistabe @FrankDElia7 @RealIvermectin @natedoromal @KStateTurk @Augusti03401363 @Monstercoyliar @cascadecrimson @SmutClyde @KrochetxKorner @jhan2qt @TinFoilAwards @BlueLionBlog @ChrisJohnsonMD @doritmi @LambourneCarol @mcfunny @immunotoxPhD @Rogue_Soc_Psych @TheFrankmanMN @GeoffSchuler @Rosewind2007 @TeddyFreddy11 @chaoticsx2 @djrazorgirl @KatLaRue7 @ianfmusgrave @cappsie @TruthTwt @microRNApro @LaLaRueFrench75 @LynnleeMavakay @WendyOrent @kidoctr @jkellyca @kfunk937 @anniecherokee @AuriaZepherine @Flying_Shadowz @LightControl2 @Takethatdoctors @Caffeine_Sam @JaneEOpie @regina1775 @wakeup89427666 @TakeThatCDC The age at diagnosis has been steadily decreasing over time. Better screening methods detect it earlier. They stratified and adjusted by birth year. How would this differ by vaccinated and unvaccinated? https://t.co/kt206Zo5oR

Jul 1, 2022 · 6 likes · 2 shares · 5,543 followers View post →
Pilgrim
@villagerssn · X

@KinseyKat1 @PeaceLillie33 @ryanbeed @cbeckj @LaceyForostoski @ThomMohr @RaggetteU @Iwontsubmit @HealthFreedomLA Ryan, yet again showing off his wealth of clinical experience. It would rare to diagnose it at birth, or even by 2 years. https://t.co/HfXwRYx41Z

Apr 10, 2024 · 5 likes · 2,615 followers View post →
Paul Whiteley
@PaulWhiteleyPhD · X

"Christchurch’s public paediatric service is no longer assessing children over six years old for autism, due to increased demand for services and a bloated waiting list." https://t.co/nSYTpgBipn That'll still pick up many e.g. https://t.co/IWgk2OtupD but some kids will be missed.

Jun 13, 2025 · 4 likes · 1 share · 4,988 followers View post →

All mentions

Veronica
@maenadea · X

Take it up with the Science. https://t.co/HhPZeow1H5

Sep 7, 2025 · 3 likes · 1,233 followers View post →
TruthSeeker
@VeritasEver · X

RT @crabb_vicki: Citations. https://t.co/cK2EFTNdwm https://t.co/EZxxRpnSj6

Aug 4, 2025 · 1 share · 4,614 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

Citations. https://t.co/cK2EFTNdwm https://t.co/EZxxRpnSj6

Aug 3, 2025 · 15 likes · 1 share · 5,543 followers View post →
Candice Chi-Hang Cheung, Ph.D.
@CandiceCheung12 · X

RT @PaulWhiteleyPhD: "Christchurch’s public paediatric service is no longer assessing children over six years old for autism, due to increa…

Jun 14, 2025 · 1 share · 1,294 followers View post →
Paul Whiteley
@PaulWhiteleyPhD · X

"Christchurch’s public paediatric service is no longer assessing children over six years old for autism, due to increased demand for services and a bloated waiting list." https://t.co/nSYTpgBipn That'll still pick up many e.g. https://t.co/IWgk2OtupD but some kids will be missed.

Jun 13, 2025 · 4 likes · 1 share · 4,988 followers View post →
Dr. nat. techn. Thomas Mohr
@ThomMohr · X

@rightwingblack2 @BGLTHMND Couldawoulda. The average age of autism Dx is not 25, but much lower. https://t.co/MmB3quFJi2

Nov 29, 2024 · 989 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@Rand73696477 @Creativologist @mass_rising @Alex_on_A14 @CaryDavid722 @SkepticalMutant @PatrickSquirrel @higgsri @FillmoreWhite @jtmayes3 @iXeno @DemsRRacePimps @ChrisJohnsonMD @JonKnudson89269 @Lorenzo7127 @Scary7Dr @cappsie @BurgerLab12 @Monstercoyliar @The_Seeadler @AndrewLazarus4 @ncdave4life @TMGFlorida @Roper_Lab @CarlSmytheCells @trillionofcells @Earthdriver @ktibus @exohalophiles @SecedeFromFools @TorySnyc @dirk_fasshauer @RonMortimer3 @mcfunny @lasikeyecenter1 @Hanky1844607 @davideyoungmd @Awithonelison @NoGlobalist778 @EugeneBu @AcampbelTeacher @EdwardDS15 @VickiCoyle10019 @FUDyou2 @smith_john55 @TheCrystalBrian @ScooterScience @RndmStreetMedic @DebraBr81576310 The statistic cited reflects global statistics. The age at diagnosis trends towards younger age in higher income countries and includes ASD. The variable is better reflected by median, not average. Mean age is influenced

Oct 20, 2024 · 2 likes · 5,543 followers View post →
Pilgrim
@villagerssn · X

@KinseyKat1 @PeaceLillie33 @ryanbeed @cbeckj @LaceyForostoski @ThomMohr @RaggetteU @Iwontsubmit @HealthFreedomLA Ryan, yet again showing off his wealth of clinical experience. It would rare to diagnose it at birth, or even by 2 years. https://t.co/HfXwRYx41Z

Apr 10, 2024 · 5 likes · 2,615 followers View post →
Pilgrim
@villagerssn · X

@PeaceLillie33 @ryanbeed @cbeckj @KinseyKat1 @LaceyForostoski @ThomMohr @RaggetteU @Iwontsubmit @HealthFreedomLA I haven't looked back at the other studies but I wonder if they limited the time frame for them as well. https://t.co/HfXwRYx41Z

Apr 10, 2024 · 2 likes · 2,615 followers View post →
Pilgrim
@villagerssn · X

@PeaceLillie33 @ryanbeed @cbeckj @KinseyKat1 @LaceyForostoski @ThomMohr @RaggetteU @Iwontsubmit @HealthFreedomLA Source for age of diagnosis. https://t.co/HfXwRYx41Z

Apr 10, 2024 · 3 likes · 2,615 followers View post →
APTCCB-officiel
@AptccbO · X

Voici les références: van ’t Hof, M., Tisseur, C., van Berckelear-Onnes, I., van Nieuwenhuyzen, A., Daniels, A. M., Deen, M., Hoek, H. W., & Ester, W. A. (2021). Age at autism spectrum disorder diagnosis: A systematic review and meta-analysis from 2012 to 2019. Autism, 25(4),

Apr 4, 2024 · 1 like · 129 followers View post →
Dude...where's my data?
@QuocplusA · X

@thesalariedGP @thereal_truther @RobertKennedyJr Please explain the study for us dummies: 1Why NO placebo control group? 2Why focus on antibody-stimulating proteins & polysaccharides but exclude the adjuvants, which are more toxic? 3Why stop at 2? The mean age of ASD diagnosis appears to be 5 years. https://t.co/YmAcCwS5Lt

Jul 26, 2023 · 95 followers View post →
Phoniatrics
@phoniatrics10 · X

Age at #Autism spectrum disorder diagnosis. Mittleres Alter bei der Diagnose von #Autismusspektrumstörung liegt bei ca. 60 Monaten https://t.co/fO2Wp3e1hD

Jul 5, 2022 · 139 followers View post →
(((Liz Ditz))). Mask up, y'all. Viruses are real.
@lizditz · X

RT @crabb_vicki: @SamathaCook45 @krebiozen @BGLTHMND @troydee @scientistabe @FrankDElia7 @RealIvermectin @natedoromal @KStateTurk @Augusti0…

Jul 2, 2022 · 2 shares · 10,487 followers View post →
Frank D’Elia
@FrankDElia7 · X

RT @crabb_vicki: @SamathaCook45 @krebiozen @BGLTHMND @troydee @scientistabe @FrankDElia7 @RealIvermectin @natedoromal @KStateTurk @Augusti0…

Jul 2, 2022 · 2 shares · 2,702 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@SamathaCook45 @krebiozen @BGLTHMND @troydee @scientistabe @FrankDElia7 @RealIvermectin @natedoromal @KStateTurk @Augusti03401363 @Monstercoyliar @cascadecrimson @SmutClyde @KrochetxKorner @jhan2qt @TinFoilAwards @BlueLionBlog @ChrisJohnsonMD @doritmi @LambourneCarol @mcfunny @immunotoxPhD @Rogue_Soc_Psych @TheFrankmanMN @GeoffSchuler @Rosewind2007 @TeddyFreddy11 @chaoticsx2 @djrazorgirl @KatLaRue7 @ianfmusgrave @cappsie @TruthTwt @microRNApro @LaLaRueFrench75 @LynnleeMavakay @WendyOrent @kidoctr @jkellyca @kfunk937 @anniecherokee @AuriaZepherine @Flying_Shadowz @LightControl2 @Takethatdoctors @Caffeine_Sam @JaneEOpie @regina1775 @wakeup89427666 @TakeThatCDC The age at diagnosis has been steadily decreasing over time. Better screening methods detect it earlier. They stratified and adjusted by birth year. How would this differ by vaccinated and unvaccinated? https://t.co/kt206Zo5oR

Jul 1, 2022 · 6 likes · 2 shares · 5,543 followers View post →
هانم♥️
@SuhafSuha · X

RT @dradilalshammar: "بناء على ٣٥ دراسة بحثية معتمدة في ٣٥ دولة، متوسط عمر التشخيص الرسمي ب التوحد للاطفال هو بعمر خمس سنوات" ⚠️⚠️إلا عند…

Nov 2, 2021 · 1 share · 204 followers View post →
عادل الشمري، BsC, MsC- Clinical Senior A & SLP/RBT
@dradilalshammar · X

"بناء على ٣٥ دراسة بحثية معتمدة في ٣٥ دولة، متوسط عمر التشخيص الرسمي ب التوحد للاطفال هو بعمر خمس سنوات" ⚠️⚠️إلا عندنا، مستعدين (البعض) للتشخيص المؤكد بالتوحد ل طفل بعمر سنه ونص!!⚠️⚠️ ⭕الاسباب كثيرة والخطأ التشخيصي مؤكد!⭕

Sep 24, 2021 · 8 likes · 1 share · 4,260 followers View post →
Pebble Autism
@PebbleAutism · X

@Mumsastudent This meta-analysis reported that from 2012-2019 the global mean age of dia was 5y5m with an average range from 2y5m to 19y6m. I suggest reading the paper to confirm those numbers as I’ve done a bit of maths on them and maths isn’t my strength! https://t.co/YmRgJhzP2i

Sep 24, 2021 · 753 followers View post →
ECNP
@ecnptweets · X

#ECNP Top Article: Age at autism spectrum disorder diagnosis: a systematic review and meta-analysis from 2012 to 2019. https://t.co/R5N09I0SjM #autism #AutismSpectrumDisorder #diagnosis #MetaAnalysis #review #study #article #ECNPTopArticle https://t.co/yQftpgpAMD

Jun 10, 2021 · 5,183 followers View post →
La Sombra Negra ....
@MissGraziellaR · X

RT @ischemgeek: @lellingw @JShahryar It's actually not. Mean age at diagnosis varies widely by study design but varies between about 1.5 ye…

Apr 17, 2021 · 1 share · 701 followers View post →
ischemgeek
@ischemgeek · X

@lellingw @JShahryar It's actually not. Mean age at diagnosis varies widely by study design but varies between about 1.5 years and 47 years. That's not a typo. I meant to type fourty-seven. Source: https://t.co/mOxDRmhxGw

Apr 17, 2021 · 3 likes · 1 share · 389 followers View post →
Dr
@draevans · X

Free #autism paper https://t.co/GsWZQBQq1D

Nov 23, 2020 · 8,480 followers View post →
NARICinfo
@NARICenEspanol · X

La edad en el momento de diagnóstico de trastorno del espectro autista #TEA: Un análisis sistemátic y un meta-anlisis de 2012 a 2019 https://t.co/wCU48L8806 en inglés vía @ignacioleyda

Nov 23, 2020 · 3 likes · 835 followers View post →
Nohemi Melgoza
@NohemiMelgoza · X

RT @ignacioleyda:

Nov 22, 2020 · 3 shares · 2,808 followers View post →
Sabina Barrios-Fernandez
@OcupaTEA · X

RT @ignacioleyda:

Nov 22, 2020 · 3 shares · 7,498 followers View post →
Manolito Schutz
@ManolitoSchutz2 · X

RT @ignacioleyda:

Nov 22, 2020 · 3 shares · 545 followers View post →
José Ignacio Leyda
@ignacioleyda · X

Nov 22, 2020 · 10 likes · 3 shares · 8,265 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @Autism_Journal: Age at autism spectrum disorder diagnosis: A systematic review and meta-analysis from 2012 to 2019. https://t.co/UEENgu…

Nov 22, 2020 · 2 shares · 6,703 followers View post →
#Autism
@Autism_Journal · X

Age at autism spectrum disorder diagnosis: A systematic review and meta-analysis from 2012 to 2019. https://t.co/UEENguoJMP #PubMed #Autism

Nov 22, 2020 · 2 shares · 388 followers View post →
松よしこ
@yosicco · X

RT @autismcrisis: Mean age at autism diagnosis ranged from 30.9 to 574.4 months & factors associated with age at diagnosis "were reported b…

Nov 20, 2020 · 2 shares · 3,830 followers View post →
Michelle Dawson
@autismcrisis · X

Mean age at autism diagnosis ranged from 30.9 to 574.4 months & factors associated with age at diagnosis "were reported by 46 studies, often with contradictory results" https://t.co/IVCHYBwoam systematic review of 56 studies published 2012-19, free

Nov 20, 2020 · 3 likes · 2 shares · 9,267 followers View post →