PubHawk
BMC Med November 2020 PMID 33213430

Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies.

Meghan A Cupp, Margarita Cariolou, Ioanna Tzoulaki, Dagfinn Aune, Evangelos Evangelou, Antonio J Berlanga-Taylor

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Mentions

11
Peak: 7 in Nov 2020
across 3 sources since Nov 2020

Extended reach

30,983
potential audience

Total likes

9

Video views

254

Mentions per month

Nov 2020 – Aug 2022

Where it's discussed

  • X / Twitter7 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The discussions show strong interest through repeated references to the review’s focus on neutrophil to lymphocyte ratios and cancer outcomes, with some posts emphasizing the potential clinical importance and calling it a 'significant step' in prognostic research. The tone suggests that viewers see the study as a meaningful contribution, supported by mentions of its 'comprehensive' nature and calls for further studies, indicating a curious yet cautious engagement with its implications.

AgreementModerate agreement

Most discussions acknowledge the validity and importance of the review, indicating general agreement with its findings.

InterestHigh interest

The frequent mention of the research and its implications suggests high interest, especially among those concerned with cancer prognosis.

EngagementModerate engagement

Participants reference specific elements such as the systematic review and its methodology, showing moderate engagement.

ImpactModerate impact

The discussions highlight the potential relevance of the review's findings for clinical practice and future research, implying moderate impact.

Abstract in brief

  • The review analyzed 204 meta-analyses examining the link between neutrophil to lymphocyte ratio (NLR) or tumor-associated neutrophils (TAN) and cancer outcomes, finding strong evidence for NLR's association with increased risk of poor prognosis in various cancers.
  • Most meta-analyses indicated that higher NLR is linked to worse cancer outcomes, especially in specific cancers like urinary, nasopharyngeal, gastric, breast, endometrial, and liver cancers, with 29 of these showing strong or highly suggestive evidence.
  • Despite promising results, the study highlights the need for further research to confirm causality and determine the clinical usefulness of NLR and TAN in predicting cancer prognosis.
Read the full abstract

Top posts

Most liked on X and Bluesky
BMC Medicine
@BMCMedicine · X

New #openaccess research from Antonio Berlanga-Taylor and colleagues: #Neutrophil to #lymphocyte ratio and #cancer #prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies Read it here: https://t.co/kJvHxahpiA https://t.co/1Jzv9KgpEC

Nov 20, 2020 · 5 likes · 4 shares · 9,190 followers View post →
BMC Medicine
@BMCMedicine · X

RT @BMCMedicine: New #openaccess research from Antonio Berlanga-Taylor and colleagues: #Neutrophil to #lymphocyte ratio and #cancer #progno…

Nov 23, 2020 · 4 shares · 9,190 followers View post →
BMC Biology
@BMCBiology · X

RT @BMCMedicine: New #openaccess research from Antonio Berlanga-Taylor and colleagues: #Neutrophil to #lymphocyte ratio and #cancer #progno…

Nov 20, 2020 · 4 shares · 9,012 followers View post →
Europe PMC articles
@EuropePMC · X

New from #The_MRC https://t.co/iTA3Qfa7I3 Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies.

Nov 22, 2020 · 1,554 followers View post →
NHS Wales Library Service (NHSWLS)
@WelshHealthLib · X

RT @BMCMedicine: New #openaccess research from Antonio Berlanga-Taylor and colleagues: #Neutrophil to #lymphocyte ratio and #cancer #progno…

Nov 20, 2020 · 4 shares · 1,052 followers View post →
MyJournals
@myjournals · X

Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies https://t.co/UFpcV6OPpi

Nov 20, 2020 · 557 followers View post →

All mentions

BMC Medicine
@BMCMedicine · X

RT @BMCMedicine: New #openaccess research from Antonio Berlanga-Taylor and colleagues: #Neutrophil to #lymphocyte ratio and #cancer #progno…

Nov 23, 2020 · 4 shares · 9,190 followers View post →
Europe PMC articles
@EuropePMC · X

New from #The_MRC https://t.co/iTA3Qfa7I3 Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies.

Nov 22, 2020 · 1,554 followers View post →
MyJournals
@myjournals · X

Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies https://t.co/UFpcV6OPpi

Nov 20, 2020 · 557 followers View post →
NHS Wales Library Service (NHSWLS)
@WelshHealthLib · X

RT @BMCMedicine: New #openaccess research from Antonio Berlanga-Taylor and colleagues: #Neutrophil to #lymphocyte ratio and #cancer #progno…

Nov 20, 2020 · 4 shares · 1,052 followers View post →
Sophie McClarty
@sophiemcclarty · X

RT @BMCMedicine: New #openaccess research from Antonio Berlanga-Taylor and colleagues: #Neutrophil to #lymphocyte ratio and #cancer #progno…

Nov 20, 2020 · 4 shares · 135 followers View post →
BMC Biology
@BMCBiology · X

RT @BMCMedicine: New #openaccess research from Antonio Berlanga-Taylor and colleagues: #Neutrophil to #lymphocyte ratio and #cancer #progno…

Nov 20, 2020 · 4 shares · 9,012 followers View post →
BMC Medicine
@BMCMedicine · X

New #openaccess research from Antonio Berlanga-Taylor and colleagues: #Neutrophil to #lymphocyte ratio and #cancer #prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies Read it here: https://t.co/kJvHxahpiA https://t.co/1Jzv9KgpEC

Nov 20, 2020 · 5 likes · 4 shares · 9,190 followers View post →