J Am Heart Assoc December 2020 PMID 33222606

Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long-Term Fasting.

Franziska Grundler, Robin Mesnage, Andreas Michalsen, Françoise Wilhelmi de Toledo

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Mentions

70
Peak: 44 in Dec 2020
across 5 sources since Nov 2020

Extended reach

827,983
potential audience

Total likes

808

Video views

19,103

Mentions per month

Nov 2020 – Mar 2025

Where it's discussed

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AI synopsis

What people are saying

The overall tone reflects a recognition of the publication's significance, with posts mentioning how fasting can normalize blood pressure even in medicated patients and highlighting its potential as a non-drug treatment, especially with phrases like 'fascinating' and 'promising.' Tone varies from curiosity to cautious optimism, driven by the emphasis on persistent effects even after reintroduction of food.

AgreementModerate agreement

Most discussions acknowledge the findings of the publication, with many citing the positive effects of fasting on blood pressure.

InterestModerate interest

The topic garners moderate interest, especially among those curious about non-pharmacological treatments for hypertension.

EngagementModerate engagement

The discussions go beyond surface-level mentions, referencing aspects like medication reduction and clinical implications.

ImpactModerate impact

There's recognition that the research could influence medical approaches and patient management, indicating a moderate potential impact.

Abstract in brief

  • This study observed blood pressure (BP) changes over long-term fasting (up to 4100 days) in 1610 participants, including those with normal and high BP, some of whom were on medication.
  • Results showed that fasting generally lowered BP, especially in hypertensive nonmedicated individuals, with reductions up to 247/131 mmHg, and even modest decreases in normotensive people; some women with lower BP experienced slight increases.
  • Factors like initial BP, BMI, glucose levels, and age influenced BP reduction magnitude, and the decrease persisted during refeeding, even when medications were stopped, indicating long-term fasting may be beneficial for managing high BP.]

Top posts

Most liked on X and Bluesky
Dr. Jason Fung
@drjasonfung · X

Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co/fbxTi9i8uW

Dec 2, 2020 · 175 likes · 32 shares · 225,374 followers View post →
IberianCitizen
@IberianCitizen · X

Cambios en la presión arterial en 1610 sujetos con y sin medicación antihipertensiva durante el ayuno prolongado https://t.co/b6VqvTTmDw https://t.co/fhTCdtNtit

Dec 2, 2020 · 15 likes · 3 shares · 12,910 followers View post →
Kipp Johnson
@kippwjohnson · X

Missed this fascinating paper from November. Fasting rapidly normalizes blood pressure in hypertensive patients. https://t.co/ma63AM4Bjw https://t.co/XHSS9HsJz7

Mar 26, 2021 · 14 likes · 1 share · 770 followers View post →
宇津 貴史 /Utsu, Takashi
@Office_j · X

【絶食にかなりの降圧作用?/ JAHA】 多職種関与、1日摂取250kcal絶食プログラム参加、1610名 [±降圧薬] 観察:4〜41日絶食で血圧は6.5/3.8mmHgの低下。降圧薬非服用「>140/90mmHg」例 [n=313] に限れば、「16.7/8.8mmHg」の低下。 https://t.co/dUTOODDSAc https://t.co/fPDhNVtQq7

Nov 24, 2020 · 6 likes · 1 share · 4,915 followers View post →
JAHA
@JAHA_AHA · X

Long-term fasting is associated with BP reductions that persist even after food reintroduction https://t.co/s9pNgQfXvx #AHAJournals https://t.co/4GsMizqbfX

Dec 1, 2020 · 5 likes · 1 share · 31,388 followers View post →
青島周一@【書籍】「生成AIと学ぶ医学論文の読み方・考え方」発売中!
@syuichiao89 · X

#未読 https://t.co/ZJtUhDTOvc https://t.co/83MNL4omDU https://t.co/0L0lSTVqvD https://t.co/9Wj7wGOAGl https://t.co/1lWyRYmW1J https://t.co/uuD8VrYduS https://t.co/v89kjFaqw1 https://t.co/dTYQL6JaSJ https://t.co/f97vtpXKRH https://t.co/3U6Gdw3PNd

Dec 1, 2020 · 3 likes · 8,605 followers View post →

All mentions

Ketogenic European
@Ketogenic_EU · X

@ClausCarlsen1 this is a nice follow up https://t.co/cpS84ssst2 Speaks to muscle enhancement

Sep 6, 2023 · 1 like · 1,027 followers View post →
Dr.Mustafa Sait YILDIZ
@MustafaSaitYIL3 · X

@NLM_NIH yer alan makalede aralıklı orucun tansiyonu olumlu etkilediği görülmüştür. Grundler, F., Mesnage, R., Michalsen, A., & Wilhelmi de Toledo, F. (2020). Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long-Term Fasting.

Jun 9, 2023 · 1,438 followers View post →
K wa K
@AMNdichu · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Mar 16, 2023 · 32 shares · 1,004 followers View post →
Robin Mesnage
@Robin_Mesnage · X

My blood pressure didn't drop so much, but it can if you are hypertensive. We published that fasting can be very potent to normalise blood pressure https://t.co/toWUC82am4 https://t.co/JPhtsnc2zh

Feb 19, 2023 · 1 like · 1,462 followers View post →
SJ
@QuantumGrav_Su · X

@KJ_tweets_ Aight yeah. When someone says Comorbidities, mind directly jumps to HT only. Not Hypotension. So in that way correct. However I did have an interesting read regarding fasting and Hypotension as well. https://t.co/3a9vUOUfCF

Feb 19, 2023 · 72 followers View post →
Effi Lifshitz
@efraimleaf · X

@ND54809416 https://t.co/6f980oRxZs

Aug 22, 2022 · 11,415 followers View post →
P-POD
@plantbasedconf · X

RT @PhD_Leigh: Could #fasting treat high #BloodPressure? Recent #research found rapid normalization of #hypertension with a long-term fasti…

Sep 13, 2021 · 1 share · 1,328 followers View post →
Leigh A. Frame
@PhD_Leigh · X

Could #fasting treat high #BloodPressure? Recent #research found rapid normalization of #hypertension with a long-term fasting protocol (10 days on average, supervised by #healthcare providers). Read the #science via @AHA_Research: https://t.co/PyNEr70CWQ #HeartHealth #nutrition https://t.co/vVJynDnKmO

Sep 10, 2021 · 2 likes · 1 share · 4,932 followers View post →
Farina M. Yusoff
@DrMYFarina · X

Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co/fExq6twVd2

Aug 31, 2021 · 197 followers View post →
Noah Zimmerman
@_noahzim_ · X

RT @kippwjohnson: Missed this fascinating paper from November. Fasting rapidly normalizes blood pressure in hypertensive patients. https:…

Mar 26, 2021 · 1 share · 1,232 followers View post →
Kipp Johnson
@kippwjohnson · X

Missed this fascinating paper from November. Fasting rapidly normalizes blood pressure in hypertensive patients. https://t.co/ma63AM4Bjw https://t.co/XHSS9HsJz7

Mar 26, 2021 · 14 likes · 1 share · 770 followers View post →
Andrea T
@Ireltash · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Jan 18, 2021 · 32 shares · 114 followers View post →
Assis, PhD
@AssisT_styx · X

Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co/PlIv1PoX6c

Dec 20, 2020 · 2 likes · 5,511 followers View post →
atif
@atifrabbani · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 9, 2020 · 32 shares · 238 followers View post →
Orlando_uy
@Orlando_uy · X

Long‐term fasting tends to decrease blood pressure in subjects with elevated BP values. This effect persisted during the 4 days of stepwise food reintroduction, even when subjects stopped their antihypertensive medication. https://t.co/CyLbRhYqrT

Dec 9, 2020 · 1 like · 694 followers View post →
TheKetoKitchen
@TheKetoKitchen_ · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 7, 2020 · 32 shares · 7,086 followers View post →
April EK
@Icutitup67 · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 5, 2020 · 32 shares · 276 followers View post →
Uptodate in Medicine
@InUptodate · X

RT @JAHA_AHA: Long-term fasting is associated with BP reductions that persist even after food reintroduction https://t.co/s9pNgQfXvx #AHAJo…

Dec 4, 2020 · 1 share · 6 followers View post →
jon furniss
@furniss_jon · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 3, 2020 · 32 shares · 924 followers View post →
Mario Rey de Landáburu
@rdlnutricion · X

RT @IberianCitizen: Cambios en la presión arterial en 1610 sujetos con y sin medicación antihipertensiva durante el ayuno prolongado https:…

Dec 3, 2020 · 3 shares · 667 followers View post →
alephh
@alephh · X

Fasting vs blood pressure (n=1610) — In hypertensive medicated group #BloodPressure decreased from 134.6/86.0 to 127.3/81.3 mm Hg: ➡️medication was stopped in 23.6% ➡️dosage was reduced in 43.5% ➡️unchanged in 19.4% — 4-41 days, ~250 kcal/day https://t.co/21bYcUtjcW #Hypertension https://t.co/xIg3Khl5nO

Dec 3, 2020 · 388 followers View post →
Orlando_uy
@Orlando_uy · X

Long‐term fasting tends to decrease BP in subjects with elevated BP values. This effect persisted during the 4 days of stepwise food reintroduction, even when subjects stopped their antihypertensive medication. https://t.co/nWdioVqbvK

Dec 3, 2020 · 1 like · 694 followers View post →
Rockne Cole
@rocknecole · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 3, 2020 · 32 shares · 519 followers View post →
Juan Jose Uceda
@UcedaJuanjo · X

RT @IberianCitizen: Cambios en la presión arterial en 1610 sujetos con y sin medicación antihipertensiva durante el ayuno prolongado https:…

Dec 2, 2020 · 3 shares · 115 followers View post →
Harvey Lang
@drlang770 · X

https://t.co/Rx6P7vF94T

Dec 2, 2020 · 32 followers View post →
Benjamin Bikman
@BenBikmanPhD · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 90,182 followers View post →
Laurie Swaney
@SwaneyLaurie · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 24 followers View post →
Lee Aase
@LeeAase · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 14,734 followers View post →
WC
@prototypicaI · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 57 followers View post →
Nacho
@NachoDominguez9 · X

RT @IberianCitizen: Cambios en la presión arterial en 1610 sujetos con y sin medicación antihipertensiva durante el ayuno prolongado https:…

Dec 2, 2020 · 3 shares · 234 followers View post →
Theo Rompas
@Theo_Rompas · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 122 followers View post →
IberianCitizen
@IberianCitizen · X

Cambios en la presión arterial en 1610 sujetos con y sin medicación antihipertensiva durante el ayuno prolongado https://t.co/b6VqvTTmDw https://t.co/fhTCdtNtit

Dec 2, 2020 · 15 likes · 3 shares · 12,910 followers View post →
J P Fanton
@HealthyFellow · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 26,024 followers View post →
UROŠ
@UrosMikolic · X

It's effective and free of charge, but for obvious reasons there is hardly any interest. Why? It can't be patented...just yet. . "Fasting appears to be a promising nonpharmacological complementary approach in the treatment of hypertension." . https://t.co/lt86qp95Hl

Dec 2, 2020 · 3,157 followers View post →
beckyb2008
@beckyb2008 · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 4 followers View post →
Κασσάνδροσ Full-time Future Forecaster until 2027.
@JeanMichelFleur · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 656 followers View post →
Lorraine Lanning
@Common_SenseCO · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 1,640 followers View post →
Tyrone13
@tyrone6140 · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 106 followers View post →
Al Soto
@AlSoto9 · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 688 followers View post →
shukrasmom
@yogasang · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 169 followers View post →
Tim Noakes
@ProfTimNoakes · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 158,590 followers View post →
BigPictureQuestions
@BigPictureQs · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 606 followers View post →
William Casey - Casey Beef LLC
@Caseyag1 · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 873 followers View post →
Patrice Boivin also @patboivin.bsky.social
@PatriceBoivin · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 534 followers View post →
Kevin Quirk
@KevinQuirk9 · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 239 followers View post →
Robert Gutierrez
@HKRED · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 1,328 followers View post →
DoctorTro
@DoctorTro · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 161,924 followers View post →
McLean Hospital, Dept. of Continuing Education
@McLeanEducation · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 394 followers View post →
Harish Tholar
@uthsav · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 41 followers View post →
Elliot
@Loh · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 6,707 followers View post →
sula
@salbanez · X

RT @drjasonfung: Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co…

Dec 2, 2020 · 32 shares · 97 followers View post →
Vivek G
@vivekgovar · X

https://t.co/coZhRuEcjb

Dec 2, 2020 · 196 followers View post →
Dr. Jason Fung
@drjasonfung · X

Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co/fbxTi9i8uW

Dec 2, 2020 · 175 likes · 32 shares · 225,374 followers View post →
Luis Rguez. Padial
@luisrpadial · X

Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting | Journal of the American Heart Association https://t.co/jeDU71ZD9P

Dec 1, 2020 · 3,032 followers View post →
JAHA
@JAHA_AHA · X

Long-term fasting is associated with BP reductions that persist even after food reintroduction https://t.co/s9pNgQfXvx #AHAJournals https://t.co/4GsMizqbfX

Dec 1, 2020 · 5 likes · 1 share · 31,388 followers View post →
青島周一@【書籍】「生成AIと学ぶ医学論文の読み方・考え方」発売中!
@syuichiao89 · X

#未読 https://t.co/ZJtUhDTOvc https://t.co/83MNL4omDU https://t.co/0L0lSTVqvD https://t.co/9Wj7wGOAGl https://t.co/1lWyRYmW1J https://t.co/uuD8VrYduS https://t.co/v89kjFaqw1 https://t.co/dTYQL6JaSJ https://t.co/f97vtpXKRH https://t.co/3U6Gdw3PNd

Dec 1, 2020 · 3 likes · 8,605 followers View post →
青島周一@【書籍】「生成AIと学ぶ医学論文の読み方・考え方」発売中!
@syuichiao89 · X

RT @Office_j: 【絶食にかなりの降圧作用?/ JAHA】 多職種関与、1日摂取250kcal絶食プログラム参加、1610名 [±降圧薬] 観察:4〜41日絶食で血圧は6.5/3.8mmHgの低下。降圧薬非服用「>140/90mmHg」例 [n=313] に限れば、…

Nov 24, 2020 · 1 share · 8,605 followers View post →
宇津 貴史 /Utsu, Takashi
@Office_j · X

【絶食にかなりの降圧作用?/ JAHA】 多職種関与、1日摂取250kcal絶食プログラム参加、1610名 [±降圧薬] 観察:4〜41日絶食で血圧は6.5/3.8mmHgの低下。降圧薬非服用「>140/90mmHg」例 [n=313] に限れば、「16.7/8.8mmHg」の低下。 https://t.co/dUTOODDSAc https://t.co/fPDhNVtQq7

Nov 24, 2020 · 6 likes · 1 share · 4,915 followers View post →
BugumKeto
@BugumKeto · X

Blood Pressure Changes in 1610 Subjects With and Without Antihypertensive Medication During Long‐Term Fasting https://t.co/UnVb7SgcjJ

Nov 24, 2020 · 562 followers View post →