PubHawk
March 2021 PMID 33258150

Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen.

Weiwen Liu, Kaitao Li, Gaofeng Wang, Lunan Yang, Qian Qu, Zhexiang Fan, Yang Sun, Junfei Huang, Yong Miao, Zhiqi Hu

Full text PDF Download social card

Mentions

9
Peak: 3 in Jan 2025
across 2 sources since Dec 2020

Extended reach

42,360
potential audience

Total likes

1,184

Video views

41,031

Mentions per month

Dec 2020 – Dec 2025

Where it's discussed

  • X / Twitter6 posts
  • YouTube3 videos

AI synopsis

What people are saying

The overall tone indicates a moderate but meaningful interest, with discussions emphasizing the potential therapeutic impact, as seen in remarks about how autophagy impairment might be rescued by agents like spermidine. Comments referencing the study’s findings demonstrate thoughtful engagement, but the tone remains exploratory rather than definitive, reflecting curiosity and anticipation about future research directions.

AgreementModerate agreement

Most discussions acknowledge the study's findings, with some expressing optimism that autophagy modulation could be beneficial for hair growth.

InterestModerate interest

Posts show moderate curiosity about the research, highlighting potential therapeutic implications and exploring related concepts like autophagy’s role in hair health.

EngagementModerate engagement

Participants reference specific parts of the publication, such as the connection between autophagy impairment and follicular miniaturization, indicating active interest and thoughtful engagement.

ImpactModerate impact

The discussions suggest that the research could influence future treatments for hair loss, reflecting perceived significance in medical and scientific communities.

Abstract in brief

  • Impaired autophagy may contribute to follicular miniaturization in androgenetic alopecia by causing premature entry into the catagen phase, which leads to hair follicle regression.
  • The study observed that early miniaturized hair follicles from balding scalps show reduced autophagy and increased cell death (apoptosis).
  • Inhibiting autophagy in cultured hair follicles worsened hair loss by promoting apoptosis and slowing hair growth, indicating that restoring autophagy might be a potential therapeutic approach.
Read the full abstract

Top posts

Most liked on X and Bluesky
Ian Mestres
@kombuchafox · X

More concretely we see - impaired autophagy https://t.co/AoxWwpJqae

Feb 28, 2022 · 2 likes · 435 followers View post →
Ian Mestres
@kombuchafox · X

Interestingly Autophagy seems to be inhibited in individuals with androgenic alopecia. It will be interesting to see research if the autophagy induced by spermidine rescues this https://t.co/zPvfbXVN8K.

Jul 5, 2021 · 435 followers View post →
PsychiatryAI.com
@PsychiatryAIcom · X

Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen https://t.co/ANmXWkCHHd

Dec 2, 2020 · 435 followers View post →
scholarR
@ivvystudent · X

@celestialbe1ng Liu W, Li K, Wang G, et al. Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen. The Journal of Dermatology. 2021;48(3):289-300. doi:10.1111/1346-8138.15672

Jan 30, 2025 · 8 followers View post →
scholarR
@ivvystudent · X

@anomalie_blue Studies show that it promotes hair growth Liu W, Li K, Wang G, et al. Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen. The Journal of Dermatology. 2021;48(3):289-300. doi:10.1111/1346-8138.15672

Jan 28, 2025 · 8 followers View post →
scholarR
@ivvystudent · X

@AlpacaAurelius Liu W, Li K, Wang G, et al. Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen. The Journal of Dermatology. 2021;48(3):289-300. doi:10.1111/1346-8138.15672

Jan 28, 2025 · 8 followers View post →

All mentions

scholarR
@ivvystudent · X

@celestialbe1ng Liu W, Li K, Wang G, et al. Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen. The Journal of Dermatology. 2021;48(3):289-300. doi:10.1111/1346-8138.15672

Jan 30, 2025 · 8 followers View post →
scholarR
@ivvystudent · X

@anomalie_blue Studies show that it promotes hair growth Liu W, Li K, Wang G, et al. Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen. The Journal of Dermatology. 2021;48(3):289-300. doi:10.1111/1346-8138.15672

Jan 28, 2025 · 8 followers View post →
scholarR
@ivvystudent · X

@AlpacaAurelius Liu W, Li K, Wang G, et al. Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen. The Journal of Dermatology. 2021;48(3):289-300. doi:10.1111/1346-8138.15672

Jan 28, 2025 · 8 followers View post →
Ian Mestres
@kombuchafox · X

More concretely we see - impaired autophagy https://t.co/AoxWwpJqae

Feb 28, 2022 · 2 likes · 435 followers View post →
Ian Mestres
@kombuchafox · X

Interestingly Autophagy seems to be inhibited in individuals with androgenic alopecia. It will be interesting to see research if the autophagy induced by spermidine rescues this https://t.co/zPvfbXVN8K.

Jul 5, 2021 · 435 followers View post →
PsychiatryAI.com
@PsychiatryAIcom · X

Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen https://t.co/ANmXWkCHHd

Dec 2, 2020 · 435 followers View post →