PubHawk
Diabetes Obes Metab March 2021 PMID 33269554

Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes.

Sophie Hallakou-Bozec, Guillaume Vial, Micheline Kergoat, Pascale Fouqueray, Sébastien Bolze, Anne-Laure Borel, Eric Fontaine, David E Moller

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Mentions

33
Peak: 5 in Jun 2021
across 4 sources since Dec 2020

Extended reach

53,085
potential audience

Total likes

67

Video views

738

Mentions per month

Dec 2020 – Jun 2025

Where it's discussed

  • X / Twitter12 posts
  • News12 articles
  • Facebook8 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions reflect a balanced interest in the article, with some posts noting Imeglimin’s unique approach to diabetes management and comparing it to drugs like metformin, supported by phrases like 'kind of like metformin... but different?' and mentions of mechanisms and safety profiles. The tone varies from cautious support to curiosity, shaping a slightly positive overall perception.

AgreementModerate agreement

Most discussions acknowledge the article's insights, with some expressing curiosity or tentative support, reflecting a generally positive stance.

InterestModerate interest

Posts show moderate interest, mentioning aspects like mechanisms and potential differences from existing drugs, indicating engagement without deep enthusiasm.

EngagementModerate engagement

Discussions reference specific mechanisms and compare Imeglimin to other medications, suggesting some level of thoughtful engagement.

ImpactModerate impact

The posts hint at the potential impact of Imeglimin in diabetes treatment, though most remain exploratory or preliminary, indicating a modest perceived influence.

Abstract in brief

  • Imeglimin is a new oral medication for treating type 2 diabetes that has shown promising results in clinical trials, including effective blood sugar control and good safety profiles without causing severe hypoglycemia.
  • Its mechanism works by boosting insulin secretion in response to glucose and improving insulin action in the liver and muscles, partly by fixing mitochondrial problems that are common in diabetes, which helps reduce oxidative stress and cell death.
  • Imeglimin’s unique approach targets the core issue of energy metabolism dysfunction in diabetes, setting it apart from other diabetes drugs like metformin, sulfonylureas, and GLP-1 receptor agonists.]
Read the full abstract

Top posts

Most liked on X and Bluesky
おだQ
@OdaQ_DM · X

主な作用は3つで， ・β細胞機能の向上，温存 ・肝臓でのインスリン感受性の改善 ・他細胞でのグルコース応答性の改善 詳しくは下記文献をどうぞ． Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes https://t.co/7jFZFl8GMD https://t.co/1CW62vVRK3

Jun 23, 2021 · 50 likes · 3 shares · 15,253 followers View post →
Dr. Om Lakhani, MD, DNB (ENDO)
@omlakhani · X

Reference: Hallakou‐Bozec S, Vial G, Kergoat M, Fouqueray P, Bolze S, Borel A, Fontaine E, Moller DE. Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes. Diabetes, Obesity and Metabolism. 2020; 23(3):664-673. DOI: 10.1111/dom.14277.

Apr 11, 2023 · 8 likes · 13,152 followers View post →
Fragarach
@Fragarach · X

Imegliminの論文読んだ。こういう分子レベルで色々効果のある薬に限って臨床効果はイマイチみたいなのはよくある話だけどこれはどうなんだろうね https://t.co/k92at0uq5E

Jul 7, 2021 · 2 likes · 2 shares · 282 followers View post →
おだQ
@OdaQ_DM · X

RT @OdaQ_DM: 主な作用は3つで， ・β細胞機能の向上，温存 ・肝臓でのインスリン感受性の改善 ・他細胞でのグルコース応答性の改善 詳しくは下記文献をどうぞ． Mechanism of action of Imeglimin: A novel therapeutic…

Sep 14, 2021 · 3 shares · 15,253 followers View post →
hr_wksh
@hr_wksh · X

RT @Fragarach: Imegliminの論文読んだ。こういう分子レベルで色々効果のある薬に限って臨床効果はイマイチみたいなのはよくある話だけどこれはどうなんだろうね https://t.co/k92at0uq5E

Aug 27, 2021 · 2 shares · 2,508 followers View post →
葵新伍
@shingo_aoi20 · X

RT @OdaQ_DM: 主な作用は3つで， ・β細胞機能の向上，温存 ・肝臓でのインスリン感受性の改善 ・他細胞でのグルコース応答性の改善 詳しくは下記文献をどうぞ． Mechanism of action of Imeglimin: A novel therapeutic…

Jun 23, 2021 · 3 shares · 1,664 followers View post →

All mentions

Dr. Om Lakhani, MD, DNB (ENDO)
@omlakhani · X

Reference: Hallakou‐Bozec S, Vial G, Kergoat M, Fouqueray P, Bolze S, Borel A, Fontaine E, Moller DE. Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes. Diabetes, Obesity and Metabolism. 2020; 23(3):664-673. DOI: 10.1111/dom.14277.

Apr 11, 2023 · 8 likes · 13,152 followers View post →
Eve Beavers Fain is espacetimeCO
@espacetimeCO · X

https://t.co/CW5P0dHAJY

Sep 29, 2021 · 912 followers View post →
Eve Beavers Fain is espacetimeCO
@espacetimeCO · X

RT @eva3034385615: (https://t.co/CW5P0dHAJY)

Sep 29, 2021 · 1 share · 912 followers View post →
Eve Beavers Fain is espacetimeCO
@espacetimeCO · X

(https://t.co/CW5P0dHAJY) https://t.co/DIRzDUgd9o

Sep 29, 2021 · 1 share · 912 followers View post →
おだQ
@OdaQ_DM · X

RT @OdaQ_DM: 主な作用は3つで， ・β細胞機能の向上，温存 ・肝臓でのインスリン感受性の改善 ・他細胞でのグルコース応答性の改善 詳しくは下記文献をどうぞ． Mechanism of action of Imeglimin: A novel therapeutic…

Sep 14, 2021 · 3 shares · 15,253 followers View post →
hr_wksh
@hr_wksh · X

RT @Fragarach: Imegliminの論文読んだ。こういう分子レベルで色々効果のある薬に限って臨床効果はイマイチみたいなのはよくある話だけどこれはどうなんだろうね https://t.co/k92at0uq5E

Aug 27, 2021 · 2 shares · 2,508 followers View post →
kidoyuichi
@yk7011 · X

RT @Fragarach: Imegliminの論文読んだ。こういう分子レベルで色々効果のある薬に限って臨床効果はイマイチみたいなのはよくある話だけどこれはどうなんだろうね https://t.co/k92at0uq5E

Jul 15, 2021 · 2 shares · 613 followers View post →
Fragarach
@Fragarach · X

Imegliminの論文読んだ。こういう分子レベルで色々効果のある薬に限って臨床効果はイマイチみたいなのはよくある話だけどこれはどうなんだろうね https://t.co/k92at0uq5E

Jul 7, 2021 · 2 likes · 2 shares · 282 followers View post →
にけ@3y3m
@nikeYAvotknueto · X

RT @OdaQ_DM: 主な作用は3つで， ・β細胞機能の向上，温存 ・肝臓でのインスリン感受性の改善 ・他細胞でのグルコース応答性の改善 詳しくは下記文献をどうぞ． Mechanism of action of Imeglimin: A novel therapeutic…

Jun 23, 2021 · 3 shares · 260 followers View post →
葵新伍
@shingo_aoi20 · X

RT @OdaQ_DM: 主な作用は3つで， ・β細胞機能の向上，温存 ・肝臓でのインスリン感受性の改善 ・他細胞でのグルコース応答性の改善 詳しくは下記文献をどうぞ． Mechanism of action of Imeglimin: A novel therapeutic…

Jun 23, 2021 · 3 shares · 1,664 followers View post →
おだQ
@OdaQ_DM · X

主な作用は3つで， ・β細胞機能の向上，温存 ・肝臓でのインスリン感受性の改善 ・他細胞でのグルコース応答性の改善 詳しくは下記文献をどうぞ． Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes https://t.co/7jFZFl8GMD https://t.co/1CW62vVRK3

Jun 23, 2021 · 50 likes · 3 shares · 15,253 followers View post →
Mike Kelly
@mikesbkelly · X

Imeglimin, it's kind of like metformin... but different? ⁦@johnbu08⁩ ⁦@EMSisson⁩ ⁦@DaveDixonPharmD⁩ ⁦@PeterAttiaMD⁩ https://t.co/IE5tNdATwY

Dec 5, 2020 · 386 followers View post →
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