February 2022 PMID 33287595

Ergothioneine Mitigates Telomere Shortening under Oxidative Stress Conditions.

Priscilla Samuel, Menelaos Tsapekos, Nuria de Pedro, Ann G Liu, J Casey Lippmeier, Steven Chen

Mentions

27
Peak: 5 in Dec 2020
across 5 sources since Dec 2020

Extended reach

85,847
potential audience

Total likes

2,605

Video views

70,145

Mentions per month

Dec 2020 – Dec 2025

Where it's discussed

  • X / Twitter10 posts
  • Facebook10 posts
  • News4 articles
  • YouTube2 videos
  • Blogs1 articles

AI synopsis

What people are saying

The discussions reflect a generally positive reception, with posts highlighting key results like longer telomeres and reduced cellular aging, using phrases such as 'significantly longer' and 'reduced rate of shortening.' The tone varies from curiosity to appreciation, with some acknowledging broader implications, indicating moderate but meaningful engagement and interest.

AgreementModerate agreement

Most discussions support the positive effects of ergothioneine on telomere preservation, with comments emphasizing its potential benefits.

InterestModerate interest

Participants show moderate interest, often mentioning the protective role of ergothioneine and its implications for aging and health.

EngagementModerate engagement

Posts reference specific research findings, such as longer telomeres and reduced shortening rates, indicating thoughtful engagement with the study.

ImpactModerate impact

The discussions suggest awareness of the research's significance, especially in aging and medical contexts, which reflects a perceived notable impact.

Abstract in brief

  • Ergothioneine, a natural antioxidant amino acid, can help maintain telomere length in human fibroblasts, especially under oxidative stress conditions, by increasing telomerase activity and reducing telomere shortening.
  • Under oxidative stress induced by hydrogen peroxide, treatment with ergothioneine resulted in longer median telomere lengths, fewer very short telomeres, and a slower rate of telomere shortening over 8 weeks.
  • These findings suggest that ergothioneine may have a protective role against cellular aging and age-related diseases by mitigating oxidative stress effects on telomeres.]

Top posts

Most liked on X and Bluesky
James W Clement
@JamesWClement · X

Ergothioneine supplementation resulted in significantly longer median telomere length and 20th percentile telomere length, and significantly reduced the percentage of short telomeres (< 3kb pairs) for all treatment concentrations after 8 weeks. https://t.co/1dyOieAkLC #AntiAging

Dec 15, 2020 · 8 likes · 2 shares · 2,157 followers View post →
老化を遅らせることに成功しているかも
@roukaokurasu · X

Aug 24, 2022 · 4 likes · 2,546 followers View post →
Peter D'Adamo
@peterdadamo · X

I get that telomere lengthening is probably good, but then again isn't telomerase is an important drug target for cancer? Despite that, everything seems to be coming up mushrooms these days. https://t.co/hj2BXKU03i

Apr 21, 2021 · 2 likes · 4,431 followers View post →
Life Length
@LifeLength · X

We are happy to have participated in this article about "Ergothioneine Mitigates Telomere Shortening under Oxidative Stress Conditionshttps" that just got published at @tandfonline #check it out: https://t.co/IQzOrApcVE @BlueCal_Ing

Dec 9, 2020 · 2 likes · 1,208 followers View post →
Vazquez, Ø
@VGO3696 · X

Ergothioneine Mitigates Telomere Shortening under Oxidative Stress Conditions https://t.co/g58QELMLT5 https://t.co/oqfw0N5BFy

Aug 21, 2024 · 2 likes · 317 followers View post →
Dr. Taylor Wallace
@DrTaylorWallace · X

#Ergothioneine helped to preserve #telomere length and reduced the rate of telomere shortening under oxidative stress. Check it out here in the Journal of Dietary Supplements. @tandfmedicine

Jan 15, 2021 · 1 like · 1 share · 2,535 followers View post →

All mentions

Vazquez, Ø
@VGO3696 · X

Ergothioneine Mitigates Telomere Shortening under Oxidative Stress Conditions https://t.co/g58QELMLT5 https://t.co/oqfw0N5BFy

Aug 21, 2024 · 2 likes · 317 followers View post →
老化を遅らせることに成功しているかも
@roukaokurasu · X

Aug 24, 2022 · 4 likes · 2,546 followers View post →
Peter D'Adamo
@peterdadamo · X

I get that telomere lengthening is probably good, but then again isn't telomerase is an important drug target for cancer? Despite that, everything seems to be coming up mushrooms these days. https://t.co/hj2BXKU03i

Apr 21, 2021 · 2 likes · 4,431 followers View post →
Juhana Harju
@JuhanaHarju · X

RT @DrTaylorWallace: #Ergothioneine helped to preserve #telomere length and reduced the rate of telomere shortening under oxidative stress.…

Apr 21, 2021 · 1 share · 1,690 followers View post →
Dr. Taylor Wallace
@DrTaylorWallace · X

#Ergothioneine helped to preserve #telomere length and reduced the rate of telomere shortening under oxidative stress. Check it out here in the Journal of Dietary Supplements. @tandfmedicine

Jan 15, 2021 · 1 like · 1 share · 2,535 followers View post →
James W Clement
@JamesWClement · X

Ergothioneine supplementation resulted in significantly longer median telomere length and 20th percentile telomere length, and significantly reduced the percentage of short telomeres (< 3kb pairs) for all treatment concentrations after 8 weeks. https://t.co/1dyOieAkLC #AntiAging

Dec 15, 2020 · 8 likes · 2 shares · 2,157 followers View post →
alephh
@alephh · X

Ergothioneine vs senescence & telomere-length — Cells preserved morphology during cell division (no #senescence) — Longer #telomere length (TL), longer 20th percentile TL, lower % of short telomeres, reductions in shortening rate https://t.co/W0cWnk2NCR #longevity #lifespan https://t.co/7c3AXlLjCO

Dec 14, 2020 · 1 like · 389 followers View post →
Xiaoying Tian
@Xiaoying_Tian · X

An interesting paper published this December showing ergothioneine reduces telomere shortening under oxidative stress condition in primary human fibroblasts. https://t.co/aDkozg1DEp

Dec 13, 2020 · 1 like · 20 followers View post →
ENDALA klinika zdraví
@endalaclinic · X

:Ergothioneine Mitigates Telomere Shortening under Oxidative Stress Conditions https://t.co/igWKHgGmpD

Dec 11, 2020 · 252 followers View post →
Life Length
@LifeLength · X

We are happy to have participated in this article about "Ergothioneine Mitigates Telomere Shortening under Oxidative Stress Conditionshttps" that just got published at @tandfonline #check it out: https://t.co/IQzOrApcVE @BlueCal_Ing

Dec 9, 2020 · 2 likes · 1,208 followers View post →
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