PubHawk
June 2021 PMID 33289165

Type 2 diabetes and remission: practical management guided by pathophysiology.

Roy Taylor

Full text PDF Download social card

Mentions

80
Peak: 18 in Dec 2020
across 4 sources since Dec 2020

Extended reach

1,615,017
potential audience

Total likes

7,574

Video views

178,842

Mentions per month

Dec 2020 – Sep 2025

Where it's discussed

  • X / Twitter70 posts
  • YouTube4 videos
  • Facebook4 posts
  • News2 articles

AI synopsis

What people are saying

Several discussions highlight the urgent message that effective weight loss is crucial for managing Type 2 diabetes, with phrases such as 'urgent signal' and concerns about 'false hopes' indicating a strong emotional response. Additionally, users reference Roy Taylor's work, suggesting a community of readers who are both interested and invested in deeper insights about diabetes management strategies.

AgreementModerate agreement

A significant number of posts affirm the idea that weight loss is essential for Type 2 diabetes management, though some express skepticism about the article's portrayal of claims.

InterestHigh interest

There's a noticeable excitement around the topic, with many users eager to discuss the research and share additional resources.

EngagementModerate engagement

Many engage in detailed discussions about the implications of the research, but some comments show signs of dismissiveness regarding the complexity of the issue.

ImpactModerate impact

The perceived impact of the article is mixed; while some users believe it can significantly influence diabetes management, others question its broader applicability and effects.

Abstract in brief

  • The twin cycle hypothesis suggests that type 2 diabetes stems from excess liver fat, which affects both the liver and pancreas, and calorie restriction can potentially reverse this condition.
  • Research, including the Counterpoint study, shows that with calorie restriction, liver function normalizes within a week, and pancreatic beta-cell function returns to near-normal levels after eight weeks, highlighting the possibility of diabetes remission.
  • Achieving remission is heavily influenced by the duration of diabetes and initial beta-cell function rather than body mass index (BMI), indicating that significant weight loss can lead to remission across different ethnic groups, emphasizing the importance of weight management in diabetes care.
Read the full abstract

Top posts

Most liked on X and Bluesky
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Type 2 diabetes is "an urgent signal that weight loss must be achieved to avoid a progressive decline of health." Unfortunately, many people and their doctors act as if diabetes was just casual; just pop some pills Diabetes can be reversed with weight loss 10.1111/joim.13214 https://t.co/fjdwUPmT8U

Sep 25, 2025 · 106 likes · 9 shares · 291,748 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/f7UkQu6OqG Regardless of your dietary composition, it is objectively the result of caloric restriction and fat loss that improves all of the markers focused on by Tro that were mentioned https://t.co/anPlC6vU2V

Dec 15, 2023 · 48 likes · 4 shares · 134,040 followers View post →
IberianCitizen
@IberianCitizen · X

Diabetes tipo 2 y remisión #obesidad https://t.co/IlZoNu7CDg https://t.co/7teLfnBn2M

Dec 28, 2020 · 21 likes · 4 shares · 12,935 followers View post →
Mauricio Gonzalez MD.
@DrMauricioGon · X

https://t.co/cmxQJxmzNJ

Mar 21, 2023 · 16 likes · 3 shares · 149,267 followers View post →
Bryce Hanna
@photobiogenesis · X

For those with acute insulin resistance or diabetes, Roy Taylor is in my opinion one of the best people to learn from Here are two of my favorite of his papers: https://t.co/8rMorxJn8G https://t.co/7lVjHTevdg

Jun 21, 2024 · 16 likes · 1 share · 34,205 followers View post →
Nick Krontiris
@nick_krontiris · X

New, by Roy Taylor: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology https://t.co/Ve7hCwSqUM #MetabolicSyndrome #Diabetes #Obesity #NALFD

Dec 10, 2020 · 14 likes · 7 shares · 19,018 followers View post →

All mentions

Jen
@JamWr1tes · X

RT @Mangan150: Type 2 diabetes is "an urgent signal that weight loss must be achieved to avoid a progressive decline of health." Unfortuna…

Sep 26, 2025 · 9 shares · 7,254 followers View post →
aintgonnaworrynomore
@aintgonnaworry1 · X

RT @Mangan150: Type 2 diabetes is "an urgent signal that weight loss must be achieved to avoid a progressive decline of health." Unfortuna…

Sep 25, 2025 · 9 shares · 4,458 followers View post →
Richard Vanderveen
@rvanderveen6002 · X

RT @Mangan150: Type 2 diabetes is "an urgent signal that weight loss must be achieved to avoid a progressive decline of health." Unfortuna…

Sep 25, 2025 · 9 shares · 43 followers View post →
Pablo Villizzianto
@villeggiante_ · X

RT @Mangan150: Type 2 diabetes is "an urgent signal that weight loss must be achieved to avoid a progressive decline of health." Unfortuna…

Sep 25, 2025 · 9 shares · 696 followers View post →
ALEX OG
@TheAlexOH · X

RT @Mangan150: Type 2 diabetes is "an urgent signal that weight loss must be achieved to avoid a progressive decline of health." Unfortuna…

Sep 25, 2025 · 9 shares · 249 followers View post →
Jesse Eureste
@jeureste13 · X

RT @Mangan150: Type 2 diabetes is "an urgent signal that weight loss must be achieved to avoid a progressive decline of health." Unfortuna…

Sep 25, 2025 · 9 shares · 342 followers View post →
GamblerNifty
@GamblerNifty · X

RT @Mangan150: Type 2 diabetes is "an urgent signal that weight loss must be achieved to avoid a progressive decline of health." Unfortuna…

Sep 25, 2025 · 9 shares · 52 followers View post →
Jon Basalyga
@jonbasalyga · X

RT @Mangan150: Type 2 diabetes is "an urgent signal that weight loss must be achieved to avoid a progressive decline of health." Unfortuna…

Sep 25, 2025 · 9 shares · 669 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Type 2 diabetes is "an urgent signal that weight loss must be achieved to avoid a progressive decline of health." Unfortunately, many people and their doctors act as if diabetes was just casual; just pop some pills Diabetes can be reversed with weight loss 10.1111/joim.13214 https://t.co/fjdwUPmT8U

Sep 25, 2025 · 106 likes · 9 shares · 291,748 followers View post →
TZO
@YngChillionaire · X

RT @Grimhood: @Sydney843 https://t.co/f7UkQu6OqG Paper on this if you’re curious for evidence.

Nov 11, 2024 · 2 shares · 174 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

RT @Grimhood: @Sydney843 https://t.co/f7UkQu6OqG Paper on this if you’re curious for evidence.

Nov 11, 2024 · 2 shares · 134,040 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

@Sydney843 https://t.co/f7UkQu6OqG Paper on this if you’re curious for evidence.

Nov 11, 2024 · 6 likes · 2 shares · 134,040 followers View post →
Daya G.✨
@4evrstardancer · X

RT @photobiogenesis: For those with acute insulin resistance or diabetes, Roy Taylor is in my opinion one of the best people to learn from…

Jun 22, 2024 · 1 share · 4,152 followers View post →
Bryce Hanna
@photobiogenesis · X

For those with acute insulin resistance or diabetes, Roy Taylor is in my opinion one of the best people to learn from Here are two of my favorite of his papers: https://t.co/8rMorxJn8G https://t.co/7lVjHTevdg

Jun 21, 2024 · 16 likes · 1 share · 34,205 followers View post →
Meghna Saha
@MeghnaSaha20 · X

@aCarnivoreDiet @AndrewM__c @BioLayne Only pathetic moron here is you. Just because you lack knowledge, doesn’t mean it’s wrong. It’s not surprising though, carnivores are typically utterly close minded. I’m sure that you won’t read, but still: https://t.co/fVU2Gk6o4A

Mar 28, 2024 · 18 followers View post →
Michael Mindrum, MD
@MichaelMindrum · X

The otherwise lovely twin cycle hypothesis describing pathway to diabetes remission missed the brain's critical role in weight regulation. This can lead to weight bias, false hopes, & learned helplessness. Don't ever forget the brain! https://t.co/cgsZKEj6TG https://t.co/TePOXWRS7T

Mar 18, 2024 · 8 likes · 9,560 followers View post →
Meghna Saha
@MeghnaSaha20 · X

@bakrantz @ScepticalDoctor If you lose fat from liver and pancreas via weight loss, you’re likely to regain full insulin functionality. https://t.co/TMWdKzNqVD

Feb 20, 2024 · 3 likes · 18 followers View post →
Trenell
@AllSabotage · X

RT @Grimhood: Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/f7UkQu6OqG Regardless of your die…

Dec 15, 2023 · 4 shares · 551 followers View post →
Sun Gorilla
@AfricangoriIla · X

RT @Grimhood: Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/f7UkQu6OqG Regardless of your die…

Dec 15, 2023 · 4 shares · 253 followers View post →
Brandon Beery
@NDominator · X

RT @Grimhood: Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/f7UkQu6OqG Regardless of your die…

Dec 15, 2023 · 4 shares · 2,918 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/f7UkQu6OqG Regardless of your dietary composition, it is objectively the result of caloric restriction and fat loss that improves all of the markers focused on by Tro that were mentioned https://t.co/anPlC6vU2V

Dec 15, 2023 · 48 likes · 4 shares · 134,040 followers View post →
Mart
@Mart23265574799 · X

RT @DrMijailTapia: Fuente https://t.co/pt8sJzlMbq

Nov 24, 2023 · 2 shares · 51 followers View post →
Sol
@ArualSogar · X

RT @DrMijailTapia: Fuente https://t.co/pt8sJzlMbq

Nov 14, 2023 · 2 shares · 794 followers View post →
Mijail Tapia, MD
@DrMijailTapia · X

Fuente https://t.co/pt8sJzlMbq

Nov 14, 2023 · 11 likes · 2 shares · 20,990 followers View post →
Konrad
@Konrad06527208 · X

@ZarzadcaTrzody @maentyfia @lekarzsuwala @DrAmbitny counterpoint study, direct study https://t.co/ZOswTcgII7.

Aug 9, 2023 · 211 followers View post →
ManekiPink
@ManekiPink · X

RT @Grimhood: @sixers2772 https://t.co/f7UkQu6OqG

Jun 19, 2023 · 1 share · 90 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

@sixers2772 https://t.co/f7UkQu6OqG

Jun 17, 2023 · 3 likes · 1 share · 134,040 followers View post →
Simon Hill MSc, BSc
@theproof · X

@coalhoof Start here: https://t.co/N3J4LKUSU9

May 13, 2023 · 3 likes · 34,176 followers View post →
Shaun Ward
@MyNutritionSci · X

Though I recommend reading this paper: https://t.co/7EEq8dt77q

Mar 29, 2023 · 6 likes · 2,385 followers View post →
Arthur Santos
@drarthursantos · X

https://t.co/c13nrRShTJ

Mar 21, 2023 · 9 followers View post →
Edmundo Alvarez
@edmundoalvarezz · X

RT @DrMauricioGon: https://t.co/cmxQJxmzNJ

Mar 21, 2023 · 3 shares · 16 followers View post →
Leonor Vásquez MD
@LeitoVr · X

RT @DrMauricioGon: https://t.co/cmxQJxmzNJ

Mar 21, 2023 · 3 shares · 977 followers View post →
Ricardo Zúñiga Nutricionista - Dietista
@nutrideliveryec · X

RT @DrMauricioGon: https://t.co/cmxQJxmzNJ

Mar 21, 2023 · 3 shares · 146 followers View post →
Mauricio Gonzalez MD.
@DrMauricioGon · X

https://t.co/cmxQJxmzNJ

Mar 21, 2023 · 16 likes · 3 shares · 149,267 followers View post →
Alex Leaf
@AlexJLeaf · X

@thefoodlearner Here is a more recent review article by him. https://t.co/wLQXRZz8Ua

Dec 5, 2022 · 2 likes · 3,966 followers View post →
James Cubarsi
@barron_john05 · X

RT @ck_eternity_: Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/B25ox1l0Ii

Aug 19, 2022 · 6 shares · 557 followers View post →
Ashish “Logmaster”
@ashishlogmaster · X

RT @ck_eternity_: Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/B25ox1l0Ii

Aug 18, 2022 · 6 shares · 922 followers View post →
Sage Against the Machine
@BCravenArt69 · X

RT @ck_eternity_: Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/B25ox1l0Ii

Aug 18, 2022 · 6 shares · 8,289 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

RT @ck_eternity_: Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/B25ox1l0Ii

Aug 18, 2022 · 6 shares · 134,040 followers View post →
Indomitablefx
@Indomitablefx · X

RT @ck_eternity_: Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/B25ox1l0Ii

Aug 8, 2022 · 6 shares · 179 followers View post →
Carlos Colmenero
@colme99 · X

RT @agingdoc1: Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/mcVZZCYI0w

Feb 20, 2022 · 1 share · 77 followers View post →
Agingdoc
@agingdoc1 · X

Type 2 diabetes and remission: practical management guided by pathophysiology https://t.co/mcVZZCYI0w

Feb 19, 2022 · 2 likes · 1 share · 41,444 followers View post →
Hanan AlThuwaini
@HananAlKuwait · X

RT @yboabbas14: إذا تم تشخيص #السكر من النوع الثاني فإني أعتقد أن دوائين أو ٣ لعلاجه بالإضافة إلي النظام الغذائي والمشي اليومي للوصول إلي #…

Sep 5, 2021 · 2 shares · 1,188 followers View post →
دكتور يوسف بوعباس
@yboabbas14 · X

RT @yboabbas14: إذا تم تشخيص #السكر من النوع الثاني فإني أعتقد أن دوائين أو ٣ لعلاجه بالإضافة إلي النظام الغذائي والمشي اليومي للوصول إلي #…

Sep 5, 2021 · 2 shares · 13,797 followers View post →
دكتور يوسف بوعباس
@yboabbas14 · X

إذا تم تشخيص #السكر من النوع الثاني فإني أعتقد أن دوائين أو ٣ لعلاجه بالإضافة إلي النظام الغذائي والمشي اليومي للوصول إلي #diabetes_remission وقد ينطبق ذلك على #الضغط https://t.co/YhcgRVvaSq #الكويت #سمنة #سكر #السعودية #SaudiArabia #diabetes #obesity #hypertension #kuwait

Sep 5, 2021 · 2 likes · 2 shares · 13,797 followers View post →
Das
@shivadas29 · X

@aldorodrigo @NephPrasad why not work on the findings of Roy Taylor and others? which may reduce some pill burden and may decrease progression of ckd ? https://t.co/WyAZD8rPbu https://t.co/DsPRix6DLe https://t.co/1PHMvLclZj

Aug 19, 2021 · 391 followers View post →
MacroFour
@MacroFour · X

@AngusTrevithick @skyking171717 @The_Nutrivore @MattMadore576 @JohnCaseIII I suggest you review that paper & this one too if you are not convinced that liver fat via DNL is the major pathway in the pathology of T2DM. https://t.co/A0BtTAmyOn

Jul 21, 2021 · 1 like · 6,069 followers View post →
Umar Hassan
@umarhere72 · X

RT @TheBhupiThakur: @DrSarahAlam Yeah thanks doc. I haven't see that review by him. This one is also great https://t.co/0sw6A3nKMg

Jul 15, 2021 · 1 share · 107 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

@DrSarahAlam Yeah thanks doc. I haven't see that review by him. This one is also great https://t.co/0sw6A3nKMg

Jul 14, 2021 · 3 likes · 1 share · 1,367 followers View post →
Das
@shivadas29 · X

@ZahcM more discussion here

Jul 13, 2021 · 1 like · 391 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @nick_krontiris: New, by Roy Taylor: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology https://t.co/Ve7hCw…

May 5, 2021 · 7 shares · 1,367 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @nick_krontiris: New, by Roy Taylor: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology https://t.co/Ve7hCw…

Feb 6, 2021 · 7 shares · 1,367 followers View post →
Jota Eme
@JotaEme93045987 · X

RT @IberianCitizen: Diabetes tipo 2 y remisión #obesidad https://t.co/IlZoNu7CDg https://t.co/7teLfnBn2M

Dec 28, 2020 · 4 shares · 58 followers View post →
Esther Serrano
@EstherSV04 · X

RT @IberianCitizen: Diabetes tipo 2 y remisión #obesidad https://t.co/IlZoNu7CDg https://t.co/7teLfnBn2M

Dec 28, 2020 · 4 shares · 345 followers View post →
Oscar Andres
@OscarAndresMD · X

RT @IberianCitizen: Diabetes tipo 2 y remisión #obesidad https://t.co/IlZoNu7CDg https://t.co/7teLfnBn2M

Dec 28, 2020 · 4 shares · 553 followers View post →
IberianCitizen
@IberianCitizen · X

Diabetes tipo 2 y remisión #obesidad https://t.co/IlZoNu7CDg https://t.co/7teLfnBn2M

Dec 28, 2020 · 21 likes · 4 shares · 12,935 followers View post →
Karl Nadolsky
@DrKarlNadolsky · X

@JamieKatuna Those are all fair, but I would look at the overall body of evidence beyond those authors looking at adiposity causing adiposopathy, insulin resistance and ultimately relative insulin deficiency. Check out the article I shared yesterday from Roy Taylor too https://t.co/rLH7coIx2i

Dec 28, 2020 · 5,860 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @DrKarlNadolsky: https://t.co/rLH7coIx2i

Dec 27, 2020 · 1 share · 1,367 followers View post →
Karl Nadolsky
@DrKarlNadolsky · X

https://t.co/rLH7coIx2i

Dec 27, 2020 · 4 likes · 1 share · 5,860 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @nick_krontiris: New, by Roy Taylor: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology https://t.co/Ve7hCw…

Dec 23, 2020 · 7 shares · 1,367 followers View post →
Echeverry Ramirez MD
@mateoeer · X

En @JInternMed aparece una revisión del Dr. Roy Taylor, recapitula la creciente evidencia de los ciclos gemelos páncreas-hígado como hipótesis del inicio de DM2. Soportado en evidencia sobre reducción de peso como la clave para romper este ciclo. Link: https://t.co/p1o8SiSSDM https://t.co/4ISkRpVa3I

Dec 16, 2020 · 1 like · 656 followers View post →
Julia B.
@JuliaB_fitness · X

RT @JuliaB_fitness: @Mangan150 Interesting, a brand new update: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiolo…

Dec 15, 2020 · 1 share · 2,271 followers View post →
Julia B.
@JuliaB_fitness · X

@Mangan150 Interesting, a brand new update: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology. 2020 «a workable explanation of how long term remission of type 2 diabetes can be achieved. It can simply be explained, doctor to patient." https://t.co/0CKsF9gvV3 https://t.co/1IFSSau1Ce

Dec 15, 2020 · 4 likes · 1 share · 2,271 followers View post →
Das
@shivadas29 · X

RT @nick_krontiris: New, by Roy Taylor: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology https://t.co/Ve7hCw…

Dec 10, 2020 · 7 shares · 391 followers View post →
Oscar Andres
@OscarAndresMD · X

RT @nick_krontiris: New, by Roy Taylor: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology https://t.co/Ve7hCw…

Dec 10, 2020 · 7 shares · 553 followers View post →
con H de heterótrofo
@NutriRebel · X

RT @nick_krontiris: New, by Roy Taylor: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology https://t.co/Ve7hCw…

Dec 10, 2020 · 7 shares · 5,955 followers View post →
Tom Babington
@Tom_Babington1 · X

RT @nick_krontiris: New, by Roy Taylor: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology https://t.co/Ve7hCw…

Dec 10, 2020 · 7 shares · 1,202 followers View post →
Nick Krontiris
@nick_krontiris · X

New, by Roy Taylor: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology https://t.co/Ve7hCwSqUM #MetabolicSyndrome #Diabetes #Obesity #NALFD

Dec 10, 2020 · 14 likes · 7 shares · 19,018 followers View post →
Agingdoc
@agingdoc1 · X

Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology https://t.co/mcVZZCH78Y

Dec 9, 2020 · 2 likes · 41,444 followers View post →
JIM - Journal of Internal Medicine
@JInternMed · X

New review: Type 2 Diabetes and Remission: Practical Management Guided by Pathophysiology #diabetes #remission #aetiology #liverfat #pancreasfat #weightloss FREE ACCESS: https://t.co/0qAisB7A7X https://t.co/e4C5Qc6HqU

Dec 4, 2020 · 1 like · 1,641 followers View post →