New Article now online: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/F35hOuTu7B
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity.
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Dec 2020 – Sep 2022Where it's discussed
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What people are saying
The discussions frequently highlight the detrimental effects of obesity on immune function and tumor growth, with phrases like 'very scary' and 'groundbreaking work' demonstrating both concern and recognition of the study's significance. Terms like 'game changer' suggest a strong awareness of the potential implications of the research, indicating that contributors are seriously contemplating how these findings might alter current understanding and treatment approaches.
Most discussions reflect a general consensus on the significant findings of the publication.
Participants express a high level of curiosity about the implications and insights presented in the article.
While many engage with the concepts, the depth of analysis varies, with some providing only surface-level commentary.
Many believe the findings could greatly influence future approaches to cancer treatment, underscoring their importance.
Abstract in brief
- Obesity significantly impacts the tumor microenvironment by impairing CD8 T cell function, leading to accelerated tumor growth.
- A detailed analysis reveals that tumor cells and CD8 T cells respond differently to diet-induced obesity, with tumor cells increasing fat uptake while CD8 T cells do not.
- Targeting the metabolic adaptations in tumors can enhance anti-tumor immunity and suggests potential strategies for improving cancer immunotherapy in humans.
Top posts
Most liked on X and Blueskycongrats to the @HaigisLab for the groundbreaking work at the intersection between obesity and cancer Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/QF5RJovcyu
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/tqR3q322ur
Check out this #singlecell metabolic atlas for cancer and immune cells in the tumor microenvironment with obesity generated by Ringel, @DrijversJefte and colleagues at @HaigisLab - now available for interactive exploration in BBrowser. Explore now: https://t.co/ZvSadP02HS https://t.co/voa5kNjAxI
Obesity impairs immune cell function, accelerates tumor growth https://t.co/H8BZk5D0HE https://t.co/EggtaAUK7F
Artículo FUNDAMENTAL en @CellCellPress en el que científicos @harvardmed desvelan algunos mecanismos que explican la relación entre #obesidad y #cancer @aec_obesidad @SociedadSeedo @PelliteroSilvia @aecirujanos @AnnaCurell @AinitzeIbarzab1 @FrutosMd https://t.co/uqAPghdN65
All mentions
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https://t.co/turnWEpQi0
RT @exosome: Proof that obesity inhibits #immunotherapy of #cancer. https://t.co/KMKtdi3zQI
@drjamesdinic I dont want to die...just read this paper...very scary did you see this paper? https://t.co/KMKtdi3zQI
Proof that obesity inhibits #immunotherapy of #cancer. https://t.co/KMKtdi3zQI
@alisoneringel is the next speaker. Among her work Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/8v9VbVZ14x This dovetails well with her talk today re: how lifestyle (incl➡️obesity), environment & aging impact cancer risk.
RT @ACS_Research: Welcome to Twitter, @alisoneringel. Give this incoming faculty member @MITBiology a follow for insights into obesity an…
The authors of "Obesity Shapes Metabolism in the Tumor Microenviro…" (https://t.co/C2Cz7R6emt) included RRIDs in their paper! Thank you for making your #methodsmatter. #RRID
RT @jcragostini2012: Así, la inflamación crónica, promovida por la obesidad y la hiperlipidemia, actúan de manera sistémica y pueden exacer…
Así, la inflamación crónica, promovida por la obesidad y la hiperlipidemia, actúan de manera sistémica y pueden exacerbar un amplio rango de enfermedades Fuente: Ringel AE. y col. Cell 183 (7): 1848-1866.E26. Dic 2020 DOI: https://t.co/Ov8B01Fc7j
RT @jcragostini: El efecto de la obesidad en el cáncer y las células del sistema inmune en el microambiente tumoral aun no está del todo de…
El efecto de la obesidad en el cáncer y las células del sistema inmune en el microambiente tumoral aun no está del todo definido Fuente: Ringel AE. y col. Cell 183 (7): 1848-1866.E26. Dic 2020 DOI: https://t.co/GhwCuFHh9e
RT @bioturing: Check out this #singlecell metabolic atlas for cancer and immune cells in the tumor microenvironment with obesity generated…
RT @bioturing: Check out this #singlecell metabolic atlas for cancer and immune cells in the tumor microenvironment with obesity generated…
RT @bioturing: Check out this #singlecell metabolic atlas for cancer and immune cells in the tumor microenvironment with obesity generated…
RT @bioturing: Check out this #singlecell metabolic atlas for cancer and immune cells in the tumor microenvironment with obesity generated…
RT @bioturing: Check out this #singlecell metabolic atlas for cancer and immune cells in the tumor microenvironment with obesity generated…
Check out this #singlecell metabolic atlas for cancer and immune cells in the tumor microenvironment with obesity generated by Ringel, @DrijversJefte and colleagues at @HaigisLab - now available for interactive exploration in BBrowser. Explore now: https://t.co/ZvSadP02HS https://t.co/voa5kNjAxI
#Obesity Shapes Metabolism in the #Tumor #Microenvironment to Suppress Anti-Tumor #Immunity: https://t.co/0GyYLyqw7A
RT @JNovickRD: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell - https://t.co/i8kxdt3kd3
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell - https://t.co/i8kxdt3kd3
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity - interesting to see tumor cells increase fat uptake with high-fat diet, whereas tumor-infiltrating CD8 + T cells do not. @CellCellPress https://t.co/Uxkj0PlLVA
Excess weight can increase the risk some cancers. Now, a study in overweight mice suggests that obesity’s effects help cancer cells to gobble fuel — depriving tumor-killing immune cells of energy. Read more: https://t.co/t5g2R6LaUW #ResearchMatters #Obesity #Cancer #Oncology https://t.co/1kcKXRNDyk
RT @ColinChampMD: Obesity provides fuel for tumor metabolism and blunts our immune response: Obesity Shapes Metabolism in the Tumor Micro…
RT @ColinChampMD: Obesity provides fuel for tumor metabolism and blunts our immune response: Obesity Shapes Metabolism in the Tumor Micro…
RT @ColinChampMD: Obesity provides fuel for tumor metabolism and blunts our immune response: Obesity Shapes Metabolism in the Tumor Micro…
RT @ColinChampMD: Obesity provides fuel for tumor metabolism and blunts our immune response: Obesity Shapes Metabolism in the Tumor Micro…
Obesity provides fuel for tumor metabolism and blunts our immune response: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/A3TqkW0laR
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/LlW2jKmSCZ
#Obesity Shapes #Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity @CellCellPress https://t.co/GiGLLFLrxa
High-fat diet (HFD)-induced obesity impairs CD8 + T cell function and accelerating tumor growth. See the summery — “Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity” ($) https://t.co/5mSlHR9lGO via #Cell Journal from @CellPressNews https://t.co/sXIjumQHM9
I won't claim this today, but I'm very confident that one of our next digital biomarkers will screen for early signs of (some types of) cancer. Alert today, alive tomorrow. #underclaiming #overdelivering #almascore #diabetesrisk…https://t.co/mTIfdEqUuF https://t.co/rOb0EJqQd4
https://t.co/G1PJ2CN1I8
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/5tOdf1OK2V
https://t.co/joy4SXcLjN https://t.co/Cu1TXdnZN9
El efecto de la #obesidad en el tratamiento y desarrollo del #cancer. #metabolismo Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/WN0ZJ0j55T
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. | Cell | https://t.co/mGW0zhaK55
RT @ACSNews: . @AmericanCancer’s senior scientific director @lwelmore0320 recommends this study: #Obesity Shapes #Metabolism in the Tumor M…
. @AmericanCancer’s senior scientific director @lwelmore0320 recommends this study: #Obesity Shapes #Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/jPks71GmZm #ACSResearchFindings https://t.co/m9o3TVpoeQ
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/aJ72ZwKI2M
Obesity impairs immune cell function, accelerates tumor growth https://t.co/H8BZk5D0HE https://t.co/EggtaAUK7F
RT @BalibreaJose: Artículo FUNDAMENTAL en @CellCellPress en el que científicos @harvardmed desvelan algunos mecanismos que explican la rela…
RT @mikachet: Key paper !!! Congrats —> Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https…
RT @BalibreaJose: Artículo FUNDAMENTAL en @CellCellPress en el que científicos @harvardmed desvelan algunos mecanismos que explican la rela…
Key paper !!! Congrats —> Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/Wi6Mu40f1u
RT @BalibreaJose: Artículo FUNDAMENTAL en @CellCellPress en el que científicos @harvardmed desvelan algunos mecanismos que explican la rela…
Harvardlı araştırmacılar tümör hücrelerinin yağdan zengin molekülleri kullanarak immün sisteme ait hücrelerin enerji metabolizmasını etkilediğini keşfetti.
RT @BalibreaJose: Artículo FUNDAMENTAL en @CellCellPress en el que científicos @harvardmed desvelan algunos mecanismos que explican la rela…
RT @BalibreaJose: Artículo FUNDAMENTAL en @CellCellPress en el que científicos @harvardmed desvelan algunos mecanismos que explican la rela…
RT @BalibreaJose: Artículo FUNDAMENTAL en @CellCellPress en el que científicos @harvardmed desvelan algunos mecanismos que explican la rela…
Artículo FUNDAMENTAL en @CellCellPress en el que científicos @harvardmed desvelan algunos mecanismos que explican la relación entre #obesidad y #cancer @aec_obesidad @SociedadSeedo @PelliteroSilvia @aecirujanos @AnnaCurell @AinitzeIbarzab1 @FrutosMd https://t.co/uqAPghdN65
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/8FdIqJTxru is was featured today at: https://t.co/MyO3yXH9vY
In obese mice, tumor cells can induce fat metabolism to steal energy from T cells, leaving the body less able to fight a faster growing tumor than in non-obese mice. Blocking this metabolic switch makes tumor cells more susceptible to T cell infiltration. https://t.co/JSy6DAsIFg https://t.co/NGsJgVchj5
RT @saludatm:
Trend up+5: **Ringel AE** et al (Cell) __Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity__ https://t.co/89PwvnDCj0
RT @IdoAmitLab: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/tqR3q322ur
肥満とがんの関係 ・高脂質の食事によりマウスのがん細胞は脂質取り込みを亢進して適応するのに対し、CD8+ T細胞はその適応を示さない→肥満によりがんの成長亢進 https://t.co/A0ae0Q6nL5
RT @agingdoc1: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/JKuErOmQWX
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/JKuErOmQWX
RT @the_paper_link: Trend up+18: **Ringel AE** et al (Cell) __Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumo…
Trend up+18: **Ringel AE** et al (Cell) __Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity__ https://t.co/89PwvnDCj0
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. https://t.co/8yDZVA0vEO https://t.co/ijbH7lTMrv
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/U11dHzu9ux
New article: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. https://t.co/ueyokdVcp2 #colorectalcancer #oncology https://t.co/9Ewl7RjGbg
RT @ralzahrani2020: a new mechanism by which obesity can interfere with the immune system’s ability to fight cancer. https://t.co/IjN794sH…
RT @ralzahrani2020: a new mechanism by which obesity can interfere with the immune system’s ability to fight cancer. https://t.co/IjN794sH…
RT @ralzahrani2020: a new mechanism by which obesity can interfere with the immune system’s ability to fight cancer. https://t.co/IjN794sH…
RT @Tweet_Nutrition: #Obesity Shapes #Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/eG0U6zXm0M
RT @FrezzaLab: congrats to the @HaigisLab for the groundbreaking work at the intersection between obesity and cancer Obesity Shapes Metabo…
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. | Cell | https://t.co/ScLW0jvqzD
RT @IdoAmitLab: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/tqR3q322ur
RT @IdoAmitLab: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/tqR3q322ur
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity @CellCellPress https://t.co/YJBzGBcU6B
RT @FrezzaLab: congrats to the @HaigisLab for the groundbreaking work at the intersection between obesity and cancer Obesity Shapes Metabo…
RT @FrezzaLab: congrats to the @HaigisLab for the groundbreaking work at the intersection between obesity and cancer Obesity Shapes Metabo…
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/phdly2f35g
RT @FrezzaLab: congrats to the @HaigisLab for the groundbreaking work at the intersection between obesity and cancer Obesity Shapes Metabo…
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/O6bJLzTd9X
#Obesity Shapes #Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/eG0U6zXm0M
RT @FrezzaLab: congrats to the @HaigisLab for the groundbreaking work at the intersection between obesity and cancer Obesity Shapes Metabo…
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity @CellCellPress https://t.co/ItBxrOrmLI
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/AcYQk9MBMd
RT @IdoAmitLab: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/tqR3q322ur
RT @IdoAmitLab: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/tqR3q322ur
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/M1CKGLzFEM
RT @FrezzaLab: congrats to the @HaigisLab for the groundbreaking work at the intersection between obesity and cancer Obesity Shapes Metabo…
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/Z5jWfNleHU
RT @CellCellPress: New Article now online: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://…
RT @FrezzaLab: congrats to the @HaigisLab for the groundbreaking work at the intersection between obesity and cancer Obesity Shapes Metabo…
RT @CellCellPress: New Article now online: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://…
congrats to the @HaigisLab for the groundbreaking work at the intersection between obesity and cancer Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/QF5RJovcyu
RT @CellCellPress: New Article now online: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://…
RT @CellCellPress: New Article now online: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://…
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity #singlecell https://t.co/fJKeeMSK63
RT @CellCellPress: New Article now online: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://…
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity | @CellCellPress by @HaigisLab https://t.co/GiGLLFLrxa
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/THOI3VZXFY
RT @IdoAmitLab: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/tqR3q322ur
RT @CellCellPress: New Article now online: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://…
RT @IdoAmitLab: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/tqR3q322ur
RT @IdoAmitLab: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/tqR3q322ur
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity: Cell https://t.co/tqR3q322ur
RT @CellCellPress: New Article now online: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://…
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/pka0y0WagO
RT @CellCellPress: New Article now online: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://…
New Article now online: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity https://t.co/F35hOuTu7B