Nutrients December 2020 PMID 33322005

Propolis Suppresses UV-Induced Photoaging in Human Skin through Directly Targeting Phosphoinositide 3-Kinase.

Da Hyun Kim, Joong-Hyuck Auh, Jeongyeon Oh, Seungpyo Hong, Sungbin Choi, Eun Ju Shin, Soon Ok Woo, Tae-Gyu Lim, Sanguine Byun

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Mentions

4
Peak: 1 in Dec 2020
across 3 sources since Dec 2020

Extended reach

1,339
potential audience

Total likes

19

Video views

401

Mentions per month

Dec 2020 – Aug 2024

Where it's discussed

  • YouTube2 videos
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  • Instagram1 posts

AI synopsis

What people are saying

The discussions reflect a positive outlook on the research, with many emphasizing the potential for natural products like propolis to combat skin aging by targeting molecular pathways such as PI3K. The tone often combines scientific detail with enthusiasm, using words like 'breakthrough,' 'promising,' and 'exciting' to underscore the importance of the findings.

AgreementModerate agreement

Most discussions express recognition and support for the publication's findings on propolis's anti-aging effects, indicating a general consensus.

InterestHigh interest

Participants show high curiosity, often highlighting the potential benefits of natural compounds like propolis and discussing its molecular mechanisms.

EngagementModerate engagement

Many discussions involve detailed explanations of how propolis inhibits PI3K and its role in skin protection, reflecting active engagement.

ImpactModerate impact

While the discussions acknowledge the significance of the findings, few mention specific real-world applications or widespread influence.

Abstract in brief

  • Propolis, a natural resin produced by bees, has multiple health benefits like antioxidative, antimicrobial, anti-inflammatory, and anticancer effects, but its specific molecular target and potential against skin aging were not fully known.
  • The study found that propolis can reduce UV-induced skin aging by decreasing the activity of MMP1, a protein that breaks down collagen in skin, thereby protecting against collagen degradation and skin aging in human tissues.
  • Propolis works by directly inhibiting the enzyme PI3K, especially targeting its p110 catalytic subunits, and compounds like caffeic acid phenethyl ester, quercetin, and apigenin in propolis help in reducing PI3K activity, which contributes to its anti-skin aging effects.]

Top posts

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The_FitAcademic
@The_FitAcademic · X

Propolis Suppresses UV-Induced Photoaging in Human Skin through Directly Targeting Phosphoinositide 3-Kinase https://t.co/zdn6sPMHYi

Dec 11, 2020 · 1 like · 929 followers View post →

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The_FitAcademic
@The_FitAcademic · X

Propolis Suppresses UV-Induced Photoaging in Human Skin through Directly Targeting Phosphoinositide 3-Kinase https://t.co/zdn6sPMHYi

Dec 11, 2020 · 1 like · 929 followers View post →
Salah satu manfaat propolis untuk kesehatan kulit = menurunkan ...
Instagram

... 10.3390/nu12123790 Propolis Suppresses UV-Induced Photoaging in Human Skin through Directly Targeting Phosphoinositide 3-Kinase #kebunefi ...

Apr 17, 2022 View →