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Front Cell Dev Biol November 2020 PMID 33324647

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction.

Sanne van der Rijt, Marte Molenaars, Rebecca L McIntyre, Georges E Janssens, Riekelt H Houtkooper

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Mentions

54
Peak: 27 in Nov 2020
across 6 sources since Nov 2020

Extended reach

226,999
potential audience

Total likes

186

Video views

3,705

Mentions per month

Nov 2020 – Mar 2023

Where it's discussed

  • X / Twitter42 posts
  • Facebook3 posts
  • Blogs3 articles
  • YouTube2 videos
  • Reddit2 posts
  • News2 articles

AI synopsis

What people are saying

The discussions emphasize the importance of mitochondrial dysfunction in aging, with comments like 'great mitochondrial metabolism' and 'beautiful read' demonstrating enthusiasm and recognition of the study’s significance. The tone is appreciative yet mostly surface-level, indicating interest and agreement but limited deep engagement or acknowledgment of major scientific shifts.

AgreementModerate agreement

Most discussions highlight the relevance of mitochondrial dysfunction in aging, suggesting general agreement with the publication's focus on this hallmark.

InterestHigh interest

Many posts express curiosity and appreciation for the research, indicating high interest, especially with comments like 'beautiful read' and mentions of the study as impactful.

EngagementModerate engagement

Participants reference specific concepts such as heterochronic parabiosis and mitochondrial pathways, showing a moderate level of detailed discussion.

ImpactModerate impact

The discussion reflects an awareness of the significance of this research area in aging science, though without clear evidence of widespread revolutionary impact yet.

Abstract in brief

  • The text explains that the hallmarks of aging, especially mitochondrial dysfunction, are interconnected and influence each other, rather than being isolated processes.
  • It describes how mitochondrial pathways like energy production, dynamics, and DNA repair relate to different aging mechanisms and how these interactions vary across different species in the tree of life.
  • The authors suggest that understanding these complex interactions could greatly advance aging research by highlighting the importance of the hallmarks' interplay and evolutionary differences.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Riekelt Houtkooper
@rhhoutkooper · X

Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (short) thread ⬇️ https://t.co/YBW90jjO7Y

Nov 26, 2020 · 48 likes · 13 shares · 1,661 followers View post →
Aging Science News
@AgingBiology · X

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https://t.co/nRStKPn5jE

Nov 26, 2020 · 29 likes · 10 shares · 31,028 followers View post →
javierbutra
@javierbutra · X

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/yqQhLHu4Qt https://t.co/fQw7RXzsWQ

Sep 22, 2022 · 11 likes · 3 shares · 14,359 followers View post →
Molly Maloof
@mollymaloofmd · X

Mitochondrial dysfunction (left) and its relation with other hallmarks (right). https://t.co/AVdRnNqHmm https://t.co/vJqPSKo0gW

Jun 9, 2022 · 8 likes · 2 shares · 5,751 followers View post →
Agingdoc
@agingdoc1 · X

Frontiers | Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction | ⁦@FrontiersIn⁩ https://t.co/Yl2zgrayiu

Feb 14, 2021 · 7 likes · 1 share · 42,472 followers View post →
Frontiers - Cell Biology
@FrontCellDevBio · X

New Research: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction: Since the identification and definition of the hallmarks of aging, these aspects of molecular and cellular decline have been… https://t.co/aJnQcQcXNQ #celldevbio

Nov 26, 2020 · 1 like · 3,802 followers View post →

All mentions

Understanding the Biological Hallmarks of Aging

As we age, our cells undergo changes that lead to functional decline. It's crucial to understand these hallmarks of aging to enhance quality of life. This video explores the interconnected hallmarks that influence aging…

Metabolismo · Jul 13, 2021 2,591 views
Leonardo Gonzalez
@md_leogonvaldi · X

RT @javierbutra: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/yqQhLHu4…

Sep 22, 2022 · 3 shares · 239 followers View post →
Octópodo
@Jappy_octopus · X

RT @javierbutra: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/yqQhLHu4…

Sep 22, 2022 · 3 shares · 1,754 followers View post →
Oscar Andres
@OscarAndresMD · X

RT @javierbutra: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/yqQhLHu4…

Sep 22, 2022 · 3 shares · 549 followers View post →
javierbutra
@javierbutra · X

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/yqQhLHu4Qt https://t.co/fQw7RXzsWQ

Sep 22, 2022 · 11 likes · 3 shares · 14,359 followers View post →
LaSalle Browne
@CertifiedBeast3 · X

RT @mollymaloofmd: Mitochondrial dysfunction (left) and its relation with other hallmarks (right). https://t.co/AVdRnNqHmm https://t.co/vJq…

Jun 18, 2022 · 2 shares · 491 followers View post →
Andrew Sheppard
@andrewsheppard · X

RT @mollymaloofmd: Mitochondrial dysfunction (left) and its relation with other hallmarks (right). https://t.co/AVdRnNqHmm https://t.co/vJq…

Jun 9, 2022 · 2 shares · 1,056 followers View post →
Molly Maloof
@mollymaloofmd · X

Mitochondrial dysfunction (left) and its relation with other hallmarks (right). https://t.co/AVdRnNqHmm https://t.co/vJqPSKo0gW

Jun 9, 2022 · 8 likes · 2 shares · 5,751 followers View post →
P. E. Sottas, PhD
@pesottas · X

Nice study. Unsurprisingly, better mitochondrial metabolism was found one of the key benefits of heterochronic parabiosis, especially oxidative phosphorylation, which is at the crossroad of the hallmarks of aging https://t.co/X8vOtUw6KX https://t.co/k8UjLfTOoz

Jan 29, 2022 · 1 like · 164 followers View post →
Orlando_uy
@Orlando_uy · X

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/Wq2O2VhZ7M

Mar 11, 2021 · 1 like · 694 followers View post →
Dromograde
@Dromograde · X

RT @agingdoc1: Frontiers | Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction | ⁦@Front…

Feb 14, 2021 · 1 share · 303 followers View post →
Agingdoc
@agingdoc1 · X

Frontiers | Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction | ⁦@FrontiersIn⁩ https://t.co/Yl2zgrayiu

Feb 14, 2021 · 7 likes · 1 share · 42,472 followers View post →
Agingdoc
@agingdoc1 · X

In case you missed it ( with the mitochondrial theme today): Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/jGO5FzGpWm @FrontAging @FrontiersIn

Jan 4, 2021 · 42,472 followers View post →
UpToPhate
@UpToPhate · X

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction. https://t.co/CnJF3lWziu

Dec 22, 2020 · 190 followers View post →
マイトファジー(Mitophagy)論文紹介
@Mitophagy_Res · X

生物種を超えた老化指標の統合的理解：ミトコンドリア機能不全から Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction. Front Cell Dev Biol. 2020 Nov 26;8:594416. https://t.co/7zAvaIDRSA

Dec 20, 2020 · 128 followers View post →
Orlando_uy
@Orlando_uy · X

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/Wq2O2VhZ7M

Dec 4, 2020 · 694 followers View post →
Hansi WEISSENSTEINER
@whansi · X

Frontiers | Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction | Cell and Developmental Biology https://t.co/Ny5pLt47YT

Nov 28, 2020 · 549 followers View post →
TAMP
@TAMPDigital · X

RT @AgingBiology: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https…

Nov 27, 2020 · 10 shares · 422 followers View post →
Diwas Srivastava
@Diwas1311 · X

An extremely beautiful read: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/md3sGgnull

Nov 27, 2020 · 116 followers View post →
Alan Hayes
@alan_hayes_vu · X

RT @AgingBiology: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https…

Nov 27, 2020 · 10 shares · 205 followers View post →
Albert J. Sarmentero.
@AlSarmentero · X

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/B2eOxqu0NS

Nov 27, 2020 · 615 followers View post →
Arktist
@Arktist · X

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction https://t.co/qKeW9lDJNY

Nov 26, 2020 · 907 followers View post →
Ariakas Enoreth
@Aenoreth · X

RT @AgingBiology: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https…

Nov 26, 2020 · 10 shares · 1,007 followers View post →
AntiAgify - Science will set you free
@AntiAgify · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 1,350 followers View post →
아나도
@msbnakwon · X

RT @AgingBiology: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https…

Nov 26, 2020 · 10 shares · 25 followers View post →
Frontiers - Cell Biology
@FrontCellDevBio · X

New Research: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction: Since the identification and definition of the hallmarks of aging, these aspects of molecular and cellular decline have been… https://t.co/aJnQcQcXNQ #celldevbio

Nov 26, 2020 · 1 like · 3,802 followers View post →
dna_imer
@ImerDna · X

RT @AgingBiology: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https…

Nov 26, 2020 · 10 shares · 547 followers View post →
Sable Systems International
@SableSys · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 1,697 followers View post →
AgingResearch
@TheAgingField · X

RT @AgingBiology: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https…

Nov 26, 2020 · 10 shares · 5,262 followers View post →
The Phoenix Lab
@The_Phoenix_Lab · X

RT @AgingBiology: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https…

Nov 26, 2020 · 10 shares · 213 followers View post →
Shahaf Peleg
@DocLarus · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 2,445 followers View post →
Emanuele Marzetti
@e_marzetti · X

RT @AgingBiology: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https…

Nov 26, 2020 · 10 shares · 265 followers View post →
Mimi_ Cardio
@mimi_cardio · X

RT @AgingBiology: Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https…

Nov 26, 2020 · 10 shares · 184 followers View post →
Aging Science News
@AgingBiology · X

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction @rhhoutkooper https://t.co/nRStKPn5jE

Nov 26, 2020 · 29 likes · 10 shares · 31,028 followers View post →
João Pedro de Magalhães
@jpsenescence · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 18,428 followers View post →
Miriam Valera-Alberni
@mitomiriam · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 714 followers View post →
Jorge I. Castillo-Quan, MD, PhD
@CastilloQuan_JI · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 2,053 followers View post →
Javi Botella
@javi_iup · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 1,068 followers View post →
Feixiong Cheng
@FeixiongCheng · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 1,361 followers View post →
Johan Van Weyenbergh
@johanvawe · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 4,753 followers View post →
Frontiers - Cell Biology
@FrontCellDevBio · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 3,802 followers View post →
FrezzaLab
@FrezzaLab · X

RT @rhhoutkooper: Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (s…

Nov 26, 2020 · 13 shares · 26,948 followers View post →
Riekelt Houtkooper
@rhhoutkooper · X

Our latest review on aging in @FrontCellDevBio, by @Sanne_vdRijt @MarteMolenaars @r_l_mcintyre and @GeorgesJanssen2. A (short) thread ⬇️ https://t.co/YBW90jjO7Y

Nov 26, 2020 · 48 likes · 13 shares · 1,661 followers View post →