Focused ultrasound surgery continues to show promise in the treatment of Parkinson's disease in a randomized phase 3 trial: https://t.co/XeXEyWDGxJ
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson's Disease.
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Dec 2020 – Apr 2025Where it's discussed
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X / Twitter100 posts
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News33 articles
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Facebook6 posts
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Bluesky3 posts
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YouTube3 videos
AI synopsis
What people are saying
Several discussions point to the significant improvements in motor features for Parkinson's patients, with posts noting phrases like 'impressive results' and 'promising treatment,' which underscore the excitement surrounding the potential of focused ultrasound. However, concerns are also raised regarding adverse effects, with one comment mentioning that 'it seems to have more side effects than DBS,' reflecting a balanced viewpoint on the treatment's advantages and drawbacks.
A majority of discussions reflect a positive acknowledgment of the findings presented in the publication.
Many participants express strong curiosity about the implications of focused ultrasound treatment for Parkinson's disease.
Posts include detailed references to the study’s findings and personal opinions, indicating a moderate level of thoughtfulness among contributors.
There is a consensus that the trial has notable implications for treatment options in Parkinson's disease, though some raise concerns about side effects.
Abstract in brief
- The subthalamic nucleus is a key target for deep-brain stimulation in Parkinson's disease, and focused ultrasound is used to create therapeutic lesions in this area.
- A clinical study randomly assigned 40 patients with asymmetric Parkinson's to receive either focused ultrasound subthalamotomy or a sham procedure, measuring motor symptoms and safety over 4 months.
- Results showed significant improvement in the MDS-UPDRS motor score for those receiving the ultrasound treatment compared to the control group, although some patients experienced adverse events like dyskinesia and speech disturbances.
Top posts
Most liked on X and BlueskyJust published in @NEJM – "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." Study led by José Obeso at @HMHOSPITALES. #parkinsons https://t.co/s9t0szB00J
Unilateral focused ultrasound subthalamotomy for Parkinson's published in the NEJM this week. A small study but impressive results. Who will the procedure be best suited for? https://t.co/bBL3O7UDQ9 @PdAvengers @ParkinsonDotOrg @endingpdbook @basbloem @DrISubramanian https://t.co/w734w32PBB
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease https://t.co/L9jywszO4n
Randomized trial of focused ultrasound subthalamotomy for parkinson’s disease ➡️ limited and retrospective-only experiences available for radiosurgery ⁉️ potential for increased research activities #radonc https://t.co/d1UfAhoSFD
Focused ultrasound subthalamotomy improved motor features in selected people with Parkinson disease https://t.co/lqOjLJ6Y7P
All mentions
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2021 week 3 selection of neurosurgical literature
RT @AstroSaito: 【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUayfA 淡蒼球 https://t.co/VPOodkwzHd 視床下核 https://t.co/AqH7k3…
【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUayfA 淡蒼球 https://t.co/VPOodkwzHd 視床下核 https://t.co/AqH7k33EgK
RT @AstroSaito: 【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUayfA 淡蒼球 https://t.co/VPOodkwzHd 視床下核 https://t.co/AqH7k3…
【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUayfA 淡蒼球 https://t.co/VPOodkwzHd 視床下核 https://t.co/AqH7k33EgK
【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUayfA 淡蒼球 https://t.co/VPOodkwzHd 視床下核 https://t.co/AqH7k33EgK
【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUrBhA 淡蒼球 https://t.co/VPOodkNCJd 視床下核 https://t.co/AqH7k3kHiK
【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUayfA 淡蒼球 https://t.co/VPOodkwzHd 視床下核 https://t.co/AqH7k33EgK
【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUrBhA 淡蒼球 https://t.co/VPOodkNCJd 視床下核 https://t.co/AqH7k3kHiK
【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUayfA 淡蒼球 https://t.co/VPOodkwzHd 視床下核 https://t.co/AqH7k33EgK
【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUrBhA 淡蒼球 https://t.co/VPOodkNCJd 視床下核 https://t.co/AqH7k3kHiK
【必読神経内科論文】 パーキンソン病に対する集束超音波療法の臨床試験の論文。 視床中間腹側核 https://t.co/YUXilUayfA 淡蒼球 https://t.co/VPOodkwzHd 視床下核 https://t.co/AqH7k33EgK
RCT of focused ultrasound subthalamotomy for Parkinson's Disease. Findings reveal improved motor features of Parkinson's disease in selected patients with asymmetric signs. #MedTwitter @MohamadBydon Click the link below to read more: https://t.co/L5HAUGb8Sl
RCT of focused ultrasound subthalamotomy for Parkinson's Disease. Findings reveal improved motor features of Parkinson's disease in selected patients with asymmetric signs. Click the link below to read more: https://t.co/46aTM0GxvS
RT @neuropuc: @fedefedeson Felicitaciones por el
@fedefedeson Felicitaciones por el
#TraineeTeamLeadTweets is where we tap iBEST trainees to share research from our themes. @RyersonU's Tyler Hornsby, our #BioMedical Imaging & Therapy team lead, shares a research paper called "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." #BIT
Click here to view the paper: https://t.co/amwcT2ppa7
#TraineeTeamLeadTweets is where we tap iBEST trainees to share research from our themes. Tyler Hornsby, a BioMedical Imaging & Therapy Lead at @RyersonU shares a research paper called "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease."
MRI-guided focused ultrasound (#MRgFUS) thalamotomy, approved for treating #essentialtremor and a subset of #Parkinsons patients, has several potential advantages over #DBS, including no need for craniotomy or indwelling hardware. https://t.co/LYekQRjxsF
RT @FUSFoundation: In "Focused Ultrasound in Parkinson’s Disease: Going Beyond Tremor," Michael Kaplitt and Alexander Ramos of @WeillCornel…
RT @FUSFoundation: In this video, Pieter Kubben, MD, (@DigNeurosurgeon) of @neurexplain provides three short overviews of recent neurosurgi…
RT @FUSFoundation: In "Focused Ultrasound in Parkinson’s Disease: Going Beyond Tremor," Michael Kaplitt and Alexander Ramos of @WeillCornel…
パーキンソン病に対する超音波視床下核破壊術に利用される @INSIGHTEC 社のExAblate 症状を有意に改善するも、構音障害、歩行障害、治療側の脱力、ジスキネジアなどの有害事象 https://t.co/4lmunmRKRJ | @NMonl https://t.co/zf1RlleUnZ | @NEJM https://t.co/adsau33MiP
In "Focused Ultrasound in Parkinson’s Disease: Going Beyond Tremor," Michael Kaplitt and Alexander Ramos of @WeillCornell provide commentary on "Randomized trial of focused ultrasound subthalamotomy for Parkinson’s disease," recently published in @NEJM. https://t.co/uxtmZ6Rc8W
In this video, Pieter Kubben, MD, (@DigNeurosurgeon) of @neurexplain provides three short overviews of recent neurosurgical literature, including a look at "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." https://t.co/aQSs1MF816
RT @SJ_Schreiner: #Parkinson disease - What’s the FUS? Will focused ultrasound #FUS subthalatomy expand the therapeutic portfolio in PD? Th…
#Parkinson disease - What’s the FUS? Will focused ultrasound #FUS subthalatomy expand the therapeutic portfolio in PD? This balanced editorial (https://t.co/nPRWsybRzy) discusses findings and implications of the recent #RCT (https://t.co/Byx2iqzcif)@NEJM. #neurology #neurosurgery
News that mattered in 2020 according to @NeurologyToday includes "Randomized trial of focused ultrasound subthalamotomy for Parkinson's disease" from @HMHOSPITALES and @UVAneurosurg https://t.co/M89CWKoJ3K
RT @neurexplain: Unilateral Focused Ultrasound Subthalamotomy in #Parkinson’s Disease https://t.co/cNkGhLJyN9 @NEJM #neurosurgery #neurolog…
Unilateral Focused Ultrasound Subthalamotomy in #Parkinson’s Disease https://t.co/cNkGhLJyN9 @NEJM #neurosurgery #neurology #FUS #visualabstract #infographic #movementdisorder #medtwitter https://t.co/tQov56qLP5
Focused ultrasound may reduce some motor symptoms of #parkinsonsdisease. https://t.co/QTBFPAgePo
Randomized trial of focused ultrasound subthalamotomy for #Parkinson’s disease: https://t.co/1s7O7NOdPr via @NEJM https://t.co/gFQr7DekQA
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/ugrGj4lbAM
Unilateral #focusedultrasound subthalamotomy improved motor features of #parkinsonsdisease in selected patients with asymmetric signs. https://t.co/MjgOh9X7h3
¿Ya vieron el regalo de navidad para los pacientes con Parkinson? Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/WVhja8oH0A
Randomized Trial of Focused Ultrasound Subthalamotomy for #Parkinson’s Disease https://t.co/z05Ht5Cuf1 #Parkinsons #research #paywall
RT @UVANeurology: Congratulations to @UVANeurology Dr. Binit Shah and Dr. Jeff Elias for their latest work in @NEJM! Focused Ultrasound Sho…
RT @UVANeurology: Congratulations to @UVANeurology Dr. Binit Shah and Dr. Jeff Elias for their latest work in @NEJM! Focused Ultrasound Sho…
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease https://t.co/vfG9mgcZM4 BY Raúl Martínez-Fernández, M.D., Ph.D., Jorge U. Máñez-Miró, M.D., Rafael Rodríguez-Rojas, Ph.D., Marta del Álamo, M.D., Binit B. Shah, M.D., Frida Hernández-Fernández, M. Sc.,
RT @ergongrupo: Subtalamotomia por ultrasonidos en la enfermedad de Párkinson https://t.co/YrYreVx274 https://t.co/VkINr5nqb3
RT @UVANeurology: Congratulations to @UVANeurology Dr. Binit Shah and Dr. Jeff Elias for their latest work in @NEJM! Focused Ultrasound Sho…
Congratulations to @UVANeurology Dr. Binit Shah and Dr. Jeff Elias for their latest work in @NEJM! Focused Ultrasound Shows Promise for Treating Parkinson’s Disease https://t.co/3nuKkp11sz via @uva @FUSFoundation @MichaelJFoxOrg @APDAParkinsons https://t.co/4Qb7wRCEon
Pıçaksız Parkinson ameliyatı, çok güvenilir dergi, güvenilir çalışma. Yan etki oranı (istemsiz hareketler, felç, konuşma zorluğu) %50 civarında. Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/19P3TNowtb
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/Dj6sJ8kZHr #Parkinsons
RT @NatRevNeurol: Focused ultrasound subthalamotomy improved motor features in selected people with Parkinson disease https://t.co/lqOjLJ6Y…
RT @NatRevNeurol: Focused ultrasound subthalamotomy improved motor features in selected people with Parkinson disease https://t.co/lqOjLJ6Y…
Ultrasound to treat Parkinson's disease? Read more here: https://t.co/lrAy8SsUmW #Parkinsons
RT @NatRevNeurol: Focused ultrasound subthalamotomy improved motor features in selected people with Parkinson disease https://t.co/lqOjLJ6Y…
Focused ultrasound subthalamotomy improved motor features in selected people with Parkinson disease https://t.co/lqOjLJ6Y7P
RT @MichaelOkun: Unilateral focused ultrasound subthalamotomy for Parkinson's published in the NEJM this week. A small study but impressive…
RT @ergongrupo: Subtalamotomia por ultrasonidos en la enfermedad de Párkinson https://t.co/YrYreVx274 https://t.co/VkINr5nqb3
RT @MichaelOkun: Unilateral focused ultrasound subthalamotomy for Parkinson's published in the NEJM this week. A small study but impressive…
Unilateral focused ultrasound subthalamotomy for Parkinson's published in the NEJM this week. A small study but impressive results. Who will the procedure be best suited for? https://t.co/bBL3O7UDQ9 @PdAvengers @ParkinsonDotOrg @endingpdbook @basbloem @DrISubramanian https://t.co/w734w32PBB
Unilateral focused ultrasound subthalamotomy for Parkinson's published in the NEJM this week. A small study but impressive results. Who will the procedure be best suited for? https://www.nejm.org/doi/full/10.1056/NEJMoa2016311?query=featured_home @PdAvengers @ParkinsonDotOrg...
RT @KullervoHynynen: Focused ultrasound surgery continues to show promise in the treatment of Parkinson's disease in a randomized phase 3 t…
RT @KullervoHynynen: Focused ultrasound surgery continues to show promise in the treatment of Parkinson's disease in a randomized phase 3 t…
RT @KullervoHynynen: Focused ultrasound surgery continues to show promise in the treatment of Parkinson's disease in a randomized phase 3 t…
Randomized trial of focused ultrasound subthalamotomy for parkinson’s disease ➡️ limited and retrospective-only experiences available for radiosurgery ⁉️ potential for increased research activities #radonc https://t.co/d1UfAhoSFD
RT @KullervoHynynen: Focused ultrasound surgery continues to show promise in the treatment of Parkinson's disease in a randomized phase 3 t…
RT @KullervoHynynen: Focused ultrasound surgery continues to show promise in the treatment of Parkinson's disease in a randomized phase 3 t…
RT @salvasapedraza: Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/0Vz8uo1AB6
Focused ultrasound surgery continues to show promise in the treatment of Parkinson's disease in a randomized phase 3 trial: https://t.co/XeXEyWDGxJ
Subtalamotomia por ultrasonidos en la enfermedad de Párkinson https://t.co/YrYreVx274 https://t.co/VkINr5nqb3
Gotta give credit to device companies that run legit RCTs with sham control arms. These sorts of studies are far too rare in medtech. @INSIGHTEC https://t.co/hGGkqAPQaA
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/0Vz8uo1AB6
RT @AmbrizMau: Subtalamotomía con ultrasonido en un hemisferio mejoró características motoras de la enfermedad de Parkinson en pacientes se…
RT @alfonso_casi: Ensayo aleatorizado de subtalamotomía con ultrasonido enfocado para la enfermedad de Parkinson: Aplicada en un hemisferio…
The results of a randomised trial of focused ultrasound subthalamotomy for #Parkinsons have been published; N=40; 27=FUS, 13=sham; UPDRS ⬇️10 points @ 4 months; Adverse events included speech & gait disturbances, weakness on the treated side, & dyskinesia https://t.co/ihfrXVgeuK https://t.co/XHeTcyo2P0
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson's Disease https://t.co/vPa0KYgsLY
Ensayo aleatorizado de subtalamotomía con ultrasonido enfocado para la enfermedad de Parkinson: Aplicada en un hemisferio mejora las características motoras de la enfermedad de Parkinson en pacientes seleccionados con signos asimétricos. ... https://t.co/2d7nu0L4mh
Focused ultrasound subthalamotomy in one hemisphere improved motor features of Parkinson’s disease in selected patients with asymmetric signs. Adverse events included speech and gait disturbances, weakness on the treated side, and dyskinesia. #medtwitter https://t.co/GPuVfSVRKd
Martínez-Fernández R, Máñez-Miró JU, Rodríguez-Rojas R, et al. Randomized trial of focused ultrasound subthalamotomy for Parkinson’s disease. N Engl J Med. 2020; 383: 2501-13. https://t.co/pphbGRjkFk #RandomizedTrial #FocusedUltrasoundSubthalamotomy #Park…https://t.co/HGkKGXoaXB
RT @FUSFoundation: Just published in @NEJM – "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." Study led by…
RT @AmbrizMau: Subtalamotomía con ultrasonido en un hemisferio mejoró características motoras de la enfermedad de Parkinson en pacientes se…
RT @tadeclinicagem: Ensaio clínico randomizado publicado no NEJM testou o uso de FUS para DP. Foram 40 pacientes com DP assimétrica que não…
RT @AmbrizMau: Subtalamotomía con ultrasonido en un hemisferio mejoró características motoras de la enfermedad de Parkinson en pacientes se…
RT @AmbrizMau: Subtalamotomía con ultrasonido en un hemisferio mejoró características motoras de la enfermedad de Parkinson en pacientes se…
Ensaio clínico randomizado publicado no NEJM testou o uso de FUS para DP. Foram 40 pacientes com DP assimétrica que não eram candidatos a ECP A melhora de sintomas foi de 50%, porém com uma taxa elevada de efeitos adversos, sendo alguns permanentes https://t.co/Cnx506lFhU
RT @AMahajanMD: @VizcarraJA Major diff.: 1. STN instead of GPi 2. Two arm RCT (FUS and sham: 2:1) instead of open label. 3. Primary outcome…
@VizcarraJA Major diff.: 1. STN instead of GPi 2. Two arm RCT (FUS and sham: 2:1) instead of open label. 3. Primary outcome: MDS-UPDRS3 instead of dyskinesia More and longer-term data needed but encouraging data for asymmetric PD especially those who can’t get DBS https://t.co/FlzQH2p47Y
RT @DrSonuBhaskar: Interesting RCT on therapeutic benefits of focused ultrasound subthalamotomy in PD patients. Improvement in motor featu…
Interesting RCT on therapeutic benefits of focused ultrasound subthalamotomy in PD patients. Improvement in motor features but notable adverse effects (?). #Parkinsons
Excellent! Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/fMIewEY8mh https://t.co/yGbMMlcu7w
TAZE TAZE... İlaçtan yarar görmeyen ve cerrahiye uygun olmayan Parkinson Hastalarının tedavisinde Odaklanmış Ultrasonografik Subtalamotomi uygulaması! Randomize Çift Kör Çalışma. Sonuç: Motor etkileri düzeltiyor ancak diskinezi gibi yan etkileri var. https://t.co/lQbXvGRzZM @NEJM https://t.co/5jw8ndajSS
RT @JuanjoArm: Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease https://t.co/L9jywszO4n
RT @JuanjoArm: Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease https://t.co/L9jywszO4n
RT @JuanjoArm: Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease https://t.co/L9jywszO4n
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease https://t.co/L9jywszO4n
RT @FUSFoundation: Just published in @NEJM – "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." Study led by…
RT @FUSFoundation: Just published in @NEJM – "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." Study led by…
Randomized Trial of Focused #Ultrasound #Subthalamotomy for #Parkinson’s Disease @NEJM https://t.co/FozQrUd6Xf
RT @FUSFoundation: Just published in @NEJM – "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." Study led by…
RT @FUSFoundation: Just published in @NEJM – "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." Study led by…
RT @beckerbarroso: Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/gQagxRkOsx
RT @FUSFoundation: Just published in @NEJM – "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." Study led by…
RT @FUSFoundation: Just published in @NEJM – "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." Study led by…
Just published in @NEJM – "Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease." Study led by José Obeso at @HMHOSPITALES. #parkinsons https://t.co/s9t0szB00J
La subtalamotomía por ultrasonido enfocado en un hemisferio mejoraría los rasgos motores del Parkinson en pacientes con signos asimétricos. Los eventos adversos incluirían alteraciones del habla y la marcha, debilidad del lado tratado y disquinesia https://t.co/QSEF3J4XJQ
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/TMJIWBdWvg
https://www.nejm.org/doi/full/10.1056/NEJMoa2016311#.X-PQAyMPl2I.twitter
Interesting study. Seems to have more side effects than DBS and is for unilateral treatment only. I will be sticking with DBS unless the pt absolutely can't have surgery Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM...
RT @beckerbarroso: Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/gQagxRkOsx
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease | NEJM https://t.co/gQagxRkOsx