Int J Mol Sci January 2021 PMID 33401674

Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid.

Fanni Tóth, Edina Katalin Cseh, László Vécsei

Mentions

15
Peak: 4 in Jul 2022
across 2 sources since Jan 2021

Extended reach

37,138
potential audience

Total likes

21

Video views

99

Mentions per month

Jan 2021 – Jul 2025

Where it's discussed

  • X / Twitter13 posts
  • YouTube2 videos

AI synopsis

What people are saying

Many discussions underscore the promising qualities of molecules like pantethine, citing its cholesterol-lowering effect and potential antiviral properties, which demonstrate interest and recognition of therapeutic implications. The tone varies from curiosity to cautious optimism, contributing to a moderate agreement and impact assessment.

AgreementModerate agreement

Most discussions recognize the potential benefits of the natural molecules linked to neuroprotection and other health benefits, indicating general support.

InterestModerate interest

The posts show curiosity and highlight specific molecules like pantethine and its effects, reflecting moderate interest in the scientific content.

EngagementModerate engagement

Posts include references to mechanisms, potential health applications, and reactions to new information, indicating active but not deep engagement.

ImpactModerate impact

While some consider the therapeutic potential of these natural compounds, the overall tone suggests they see incremental contributions rather than revolutionary changes.

Abstract in brief

  • This text discusses the increasing incidence of neurodegenerative diseases and the challenges in finding effective neuroprotective agents, highlighting the potential of natural molecules due to their diverse biological activities.
  • It focuses on three natural molecules: kynurenic acid, which helps prevent glutamate excitotoxicity; pantethine, a well-tolerated dietary supplement; and lipoic acid, a universal antioxidant, all of which show promise for neuroprotection.
  • The conclusion emphasizes that these molecules, because of their beneficial properties, could be suitable candidates for developing therapies to manage neurodegenerative diseases.

Top posts

Most liked on X and Bluesky
Rene Sugar
@renesugar · X

Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "pantethine mitigates metabolic dysfunctions and decreases astrogliosis and IL-1β production" https://t.co/ub09VAFkJ2

Jul 12, 2022 · 14 likes · 4 shares · 3,985 followers View post →
Rene Sugar
@renesugar · X

Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "The combined supplementation of LA + ALCAR improved mitochondrial lipid composition, blocked mitochondrial structural changes, and mitigated cognitive deficits"

Jul 12, 2022 · 4 likes · 3,985 followers View post →
Rene Sugar
@renesugar · X

Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "Pantethine depleted cystine as effectively as cysteamine in cystinotic fibroblast cell cultures, so pantethine can be an alternative for cystinosis treatment"

Dec 13, 2021 · 1 like · 3,985 followers View post →
CopperKettle
@Artyom_Yekat · X

Curious molecule I've just learned about: pantethine, derived from vitamin B5 and somehow mysteriously decreasing LDL cholesterol. To read up.https://t.co/5ElJZY8AGN

May 24, 2025 · 1 like · 381 followers View post →
Rene Sugar
@renesugar · X

@AdvancedTweaker eg. pantethine (900mg - 1200mg / day) can lower cholesterol Potential antiviral effects of pantethine against SARS-CoV-2 https://t.co/LxR7t5k1p5 Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/cAQsIsR5is

Jun 28, 2025 · 3,985 followers View post →
Rene Sugar
@renesugar · X

RT @renesugar: Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "pantethine m…

Jun 4, 2025 · 4 shares · 3,985 followers View post →

All mentions

Alexander Zbiciak
@IBreakData · X

@fire_bottle @exfatloss @TMKehrenberg @bradstradamus https://t.co/0XC4t3JHcF Discusses kynurenic acid, pantethine and α-lipoic acid.

Jul 7, 2025 · 19 followers View post →
Rene Sugar
@renesugar · X

@AdvancedTweaker eg. pantethine (900mg - 1200mg / day) can lower cholesterol Potential antiviral effects of pantethine against SARS-CoV-2 https://t.co/LxR7t5k1p5 Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/cAQsIsR5is

Jun 28, 2025 · 3,985 followers View post →
Rene Sugar
@renesugar · X

RT @renesugar: Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "pantethine m…

Jun 4, 2025 · 4 shares · 3,985 followers View post →
CopperKettle
@Artyom_Yekat · X

Curious molecule I've just learned about: pantethine, derived from vitamin B5 and somehow mysteriously decreasing LDL cholesterol. To read up.https://t.co/5ElJZY8AGN

May 24, 2025 · 1 like · 381 followers View post →
Rene Sugar
@renesugar · X

RT @renesugar: Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "pantethine m…

Jan 23, 2024 · 4 shares · 3,985 followers View post →
Rene Sugar
@renesugar · X

RT @renesugar: Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "pantethine m…

Jan 30, 2023 · 4 shares · 3,985 followers View post →
Rene Sugar
@renesugar · X

RT @renesugar: Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "Pantethine is…

Jul 23, 2022 · 1 share · 3,985 followers View post →
Ramona G
@RamonaGorasciuc · X

RT @renesugar: Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "pantethine m…

Jul 13, 2022 · 4 shares · 654 followers View post →
Rene Sugar
@renesugar · X

Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "The combined supplementation of LA + ALCAR improved mitochondrial lipid composition, blocked mitochondrial structural changes, and mitigated cognitive deficits"

Jul 12, 2022 · 4 likes · 3,985 followers View post →
Rene Sugar
@renesugar · X

Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "pantethine mitigates metabolic dysfunctions and decreases astrogliosis and IL-1β production" https://t.co/ub09VAFkJ2

Jul 12, 2022 · 14 likes · 4 shares · 3,985 followers View post →
Rene Sugar
@renesugar · X

Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "Pantethine is significantly more effective than diet in lowering the serum lipid content (triglyceride (TG), total Chol and low-density lipoprotein cholesterol), with"

Dec 13, 2021 · 1 share · 3,985 followers View post →
Rene Sugar
@renesugar · X

Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid https://t.co/hyDYQ5nsgl "Pantethine depleted cystine as effectively as cysteamine in cystinotic fibroblast cell cultures, so pantethine can be an alternative for cystinosis treatment"

Dec 13, 2021 · 1 like · 3,985 followers View post →
湘南なぎさクラブ*パーキンソン病患者家族会
@ShonanNagisaC · X

天然分子と神経保護。キヌレン酸、パンテチン、α-リポ酸 「1.神経保護剤であるキヌレニン酸、2.安全性の高い栄養補助食品パンテチン、3.普遍的な抗酸化物質であるα-リポ酸である第三の天然分子, 神経変性疾患の管理に適した神経保護療法の潜在的候補」 Molecular Sciences https://t.co/CCMcC4HWAk

Jan 4, 2021 · 77 followers View post →