The discussions show strong agreement with the article's findings, with users citing examples such as the meta-analysis showing mood improvements up to 60 days, and emphasizing the therapeutic potential with words like 'promising' and 'game changer.' The tone and choice of words reflect high interest and belief in the importance of these findings for future mental health practices.
AgreementStrong agreement
Most discussions express strong support for the findings, emphasizing the positive therapeutic potential of psychedelics.
InterestHigh interest
The posts demonstrate high curiosity, highlighting meta-analyses, key studies, and the significance of the results.
EngagementHigh engagement
Many discussions include detailed references to specific studies, effect sizes, and methodological considerations, indicating deep engagement.
ImpactHigh impact
There is broad consensus that this research could have a transformative effect on mental health treatment, underscored by phrases like 'promising data' and 'significant effects.'
Abstract in brief
This meta-analysis reviews 12 studies involving both healthy individuals and those with mood disorders to evaluate the effects of classic serotonergic psychedelics like psilocybin, LSD, and ayahuasca on mood and depression symptoms.
Results showed that psychedelics provided moderate to significant improvements in mood immediately after treatment and up to 60 days later, especially in reducing depression symptoms in mood disorder patients.
Despite concerns about unblinding and expectancy effects, the fast and lasting mood improvements suggest that these psychedelics have strong therapeutic potential, warranting more rigorous clinical trials.]
The first in-depth #psychedelics meta-analysis for #depression & negative #mood state. We found very promising data... Further robust research still needing to occur, with application within a psychotherapeutic framework & adequate medical oversight @MAPS https://t.co/7EtYENJL6j
Jan 11, 2021 · 34 likes · 9 shares · 343 followersView post →
MD
Mike Hart, M.D
@drmikehart · X
Psychedelics can improve mood in both healthy subjects and patients with mood disorders.
The improved mood was observed in healthy subjects immediately after use and lasted up to 60 days.
Depression was acutely alleviated in those with mood disorders.
https://t.co/inOuMar6ZS
Jan 25, 2021 · 28 likes · 8 shares · 66,610 followersView post →
GD
Grinspoon: Grinspoon on Drugs
@Peter_Grinspoon · X
For patients with mood disorder, significant effect sizes were detected on the acute, medium (2–7 days after treatment) & longer-term outcomes favoring psychedelics on the reduction of depressive symptoms.
(one problem: blinding with #psychedelics)
https://t.co/BywXeQI3Wl
Jan 20, 2021 · 6 likes · 1 share · 35,369 followersView post →
SL
Sean Last
@Sean__Last · X
Latest meta-analysis of the small sample studies on how psychedelic's impact depression. Still finds such drugs have positive effects. But the data is still of low quality.
https://t.co/hR8pEgf4Ld
Feb 20, 2021 · 5 likes · 2 shares · 10,408 followersView post →
CI
Chacruna Institute
@Chacruna_Inst · X
Meta-analytic review of classic serotonergic psychedelics found significant effect sizes for the acute, medium (2–7 days after treatment), and longer-term outcomes favoring psychedelics over placebo on the reduction of depressive symptoms.
https://t.co/lntmvyLYTd https://t.co/9Ed3SX7vJv
Jan 17, 2021 · 4 likes · 2 shares · 12,581 followersView post →
MD
Mike Hart, M.D
@drmikehart · X
Patients with & without mood disorders can benefit from psychedelics.
Healthy volunteers benefit from psychedelics both acutely and in the long-term.
Patients with mood disorders report alleviation of depression both acutely and in the long-term.
https://t.co/inOuMar6ZS
Feb 8, 2021 · 3 likes · 1 share · 66,610 followersView post →
The Monster Monday Monster Cast discusses therapeutic effects of serotonergic psychedelics like psilocybin, LSD, and ayahuasca on mood and depression. The show features segments on media, sports, and psychedelic…
This review discusses the use of psychedelics in mental health treatment, highlighting significant improvements in mood and depression symptoms observed in recent studies, especially in mood disorder patients. The…
Meta-analyses on effects + therapy:
psilocybin, LSD, ayahuasca on mood disorders and depression https://t.co/BvhscQqdyx
psilocybin on anxiety and depression
https://t.co/8472mNCDAN
psilocybin, ayahuasca, LSD on depression
https://t.co/H5odtsz2pC
@armerner_psych One of these?
https://t.co/6pF0gxsCFu
https://t.co/T2FnJgEdLR
https://t.co/y5A4fTeHKm
https://t.co/tpssDRcE89
https://t.co/7ZMoPwSRas
Jan 14, 2023 · 2 likes · 6,182 followersView post →
PN
Psicodélicos News
@psiquedelicos · X
2021. Metanálise de 12 estudos clínicos controlados e randomizados sobre uso de psicodélicos serotoninergicos clássicos no tratamento de sintomas depressivos. Apesar da amostra total ser pequena, todos os estudos evidenciaram boa resposta terapêutica.
https://t.co/2b4FfdbKoC
First meta-analytic review evaluating the clinical effects of classic #serotonergic #psychedelics vs #placebo for #mood disorders.https://t.co/vR8JXXldqA #nursepractitioner #mentalhealth #psychiatry #medicine #primarycare #depression #mhchat #mh #Psilocybin
We didn't include studies with healthy (non-depressed) participants which usually are done first as open-label
Two of the best-known psilocybin studies (Griffiths et al 2006, Hasler et al 2004) are thus not included
For all notable psi studies
https://t.co/vIIR5m59tc 3/8
RT @ViewsOnDrugsBot: Classic #serotonergic #psychedelics for mood and depressive symptoms: a #meta-analysis of mood disorder patients and h…
Jun 26, 2021 · 3 shares · 2,055 followersView post →
AA
Amsterdam Psychedelic Research Association (APRA)
@APRAresearch · X
Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants https://t.co/fAqZd2I9xX
RT @Sean__Last: Latest meta-analysis of the small sample studies on how psychedelic's impact depression. Still finds such drugs have positi…
Feb 20, 2021 · 2 shares · 1,706 followersView post →
S
SystematicReviewBot
@EvidenceRobot · X
RT @Sean__Last: Latest meta-analysis of the small sample studies on how psychedelic's impact depression. Still finds such drugs have positi…
Feb 20, 2021 · 2 shares · 6,693 followersView post →
SL
Sean Last
@Sean__Last · X
Latest meta-analysis of the small sample studies on how psychedelic's impact depression. Still finds such drugs have positive effects. But the data is still of low quality.
https://t.co/hR8pEgf4Ld
Feb 20, 2021 · 5 likes · 2 shares · 10,408 followersView post →
VD
Views on Drugs
@ViewsOnDrugsBot · X
RT @drugSciBot: Classic #serotonergic #psychedelics for mood and depressive symptoms: a #meta-analysis of mood disorder patients and health…
Feb 18, 2021 · 2 shares · 2,055 followersView post →
S
SystematicReviewBot
@EvidenceRobot · X
RT @drugSciBot: Classic #serotonergic #psychedelics for mood and depressive symptoms: a #meta-analysis of mood disorder patients and health…
Feb 18, 2021 · 2 shares · 6,693 followersView post →
VD
Views on Drugs
@ViewsOnDrugsBot · X
Classic #serotonergic #psychedelics for mood and depressive symptoms: a #meta-analysis of mood disorder patients and healthy participants https://t.co/lC5seGlPxC
Feb 18, 2021 · 2 shares · 2,055 followersView post →
NS
Noia Soft
@menezes98biel · X
https://t.co/8RVvBP2qlq
Artigo sobre o uso de psicodélicos (LSD, Ayuhasca e cogumelos) em psicoterapia assistida e a eficácia pra depressão e transtornos psilogicos ❤️❤️❤️❤️❤️❤️
Patients with & without mood disorders can benefit from psychedelics.
Healthy volunteers benefit from psychedelics both acutely and in the long-term.
Patients with mood disorders report alleviation of depression both acutely and in the long-term.
https://t.co/inOuMar6ZS
Feb 8, 2021 · 3 likes · 1 share · 66,610 followersView post →
K
Kassie
@KassandraKitson · X
RT @drmikehart: Psychedelics can improve mood in both healthy subjects and patients with mood disorders.
The improved mood was observed i…
Jan 31, 2021 · 8 shares · 13,721 followersView post →
JC
José Carlos
@JoselitoCarloss · X
RT @drmikehart: Psychedelics can improve mood in both healthy subjects and patients with mood disorders.
The improved mood was observed i…
RT @drmikehart: Psychedelics can improve mood in both healthy subjects and patients with mood disorders.
The improved mood was observed i…
Jan 26, 2021 · 8 shares · 3,621 followersView post →
TN
Truth Seeker NYC
@TruthSeeker2160 · X
RT @drmikehart: Psychedelics can improve mood in both healthy subjects and patients with mood disorders.
The improved mood was observed i…
Jan 25, 2021 · 8 shares · 1,182 followersView post →
MP
Mind Escape Podcast
@MikeEscape · X
RT @drmikehart: Psychedelics can improve mood in both healthy subjects and patients with mood disorders.
The improved mood was observed i…
Jan 25, 2021 · 8 shares · 4,079 followersView post →
HD
Henrik (dadnoises)
@dengamleochlede · X
RT @drmikehart: Psychedelics can improve mood in both healthy subjects and patients with mood disorders.
The improved mood was observed i…
Jan 25, 2021 · 8 shares · 906 followersView post →
CC
Canadian Cossack
@CanadianCossak · X
RT @drmikehart: Psychedelics can improve mood in both healthy subjects and patients with mood disorders.
The improved mood was observed i…
Jan 25, 2021 · 8 shares · 1,034 followersView post →
MD
Mike Hart, M.D
@drmikehart · X
Psychedelics can improve mood in both healthy subjects and patients with mood disorders.
The improved mood was observed in healthy subjects immediately after use and lasted up to 60 days.
Depression was acutely alleviated in those with mood disorders.
https://t.co/inOuMar6ZS
Jan 25, 2021 · 28 likes · 8 shares · 66,610 followersView post →
PD
Pugachev with a Ph.D.
@chernyshesvky · X
RT @Peter_Grinspoon: For patients with mood disorder, significant effect sizes were detected on the acute, medium (2–7 days after treatment…
First meta-analytic review evaluating the clinical effects of classic serotonergic psychedelics vs placebo for mood state and symptoms of depression https://t.co/D2aDIOFLfY
For patients with mood disorder, significant effect sizes were detected on the acute, medium (2–7 days after treatment) & longer-term outcomes favoring psychedelics on the reduction of depressive symptoms.
(one problem: blinding with #psychedelics)
https://t.co/BywXeQI3Wl
Jan 20, 2021 · 6 likes · 1 share · 35,369 followersView post →
D
DdC
@DendeCannabist · X
Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants
https://t.co/GxhKAdPpp2 https://t.co/O9c3nJ5i9A
The abstract of this free full-text paper reads: "Rationale Major depressive disorder is one of the leading global causes of disability, for which the classic serotonergic psychedelics have recently reemerged as a potential therapeutic treatment option.
https://t.co/cSO6nFJBNM https://t.co/GnKY5r3IZl
La revisión metaanalítica de los psicodélicos clásicos encontró el tamaño de los efectos significativos para los resultados agudos, medios (2 a 7 días después del tratamiento) y a largo plazo sobre el placebo en la reducción de los síntomas depresivos.
RT @Chacruna_net: Meta-analytic review of classic serotonergic psychedelics found significant effect sizes for the acute, medium (2–7 days…
Jan 18, 2021 · 2 shares · 425 followersView post →
T
TripsForTheSoul
@Tripsforthesoul · X
RT @Chacruna_net: Meta-analytic review of classic serotonergic psychedelics found significant effect sizes for the acute, medium (2–7 days…
Jan 18, 2021 · 2 shares · 826 followersView post →
CI
Chacruna Institute
@Chacruna_Inst · X
Meta-analytic review of classic serotonergic psychedelics found significant effect sizes for the acute, medium (2–7 days after treatment), and longer-term outcomes favoring psychedelics over placebo on the reduction of depressive symptoms.
https://t.co/lntmvyLYTd https://t.co/9Ed3SX7vJv
Jan 17, 2021 · 4 likes · 2 shares · 12,581 followersView post →
S
SystematicReviewBot
@EvidenceRobot · X
RT @YockeyAndrew: Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy…
Jan 16, 2021 · 2 shares · 6,693 followersView post →
DZ
Dr. Z
@outofthewoodZ_ · X
RT @YockeyAndrew: Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy…
Jan 16, 2021 · 2 shares · 793 followersView post →
AH
Andrew Yockey, PhD (He/Him)
@YockeyAndrew · X
Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants | SpringerLink https://t.co/aFYIfQWRc0
Jan 16, 2021 · 2 likes · 2 shares · 1,208 followersView post →
S
SystematicReviewBot
@EvidenceRobot · X
RT @UpToPhate: Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy pa…
Jan 16, 2021 · 1 share · 6,693 followersView post →
U
UpToPhate
@UpToPhate · X
Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants. https://t.co/Lvxq6hTh6e
Jan 16, 2021 · 2 likes · 1 share · 197 followersView post →
VD
Views on Drugs
@ViewsOnDrugsBot · X
RT @drugSciBot: Classic #serotonergic #psychedelics for mood and depressive symptoms: a #meta-analysis of mood disorder patients and health…
Jan 16, 2021 · 3 shares · 2,055 followersView post →
S
SystematicReviewBot
@EvidenceRobot · X
RT @drugSciBot: Classic #serotonergic #psychedelics for mood and depressive symptoms: a #meta-analysis of mood disorder patients and health…
Jan 16, 2021 · 3 shares · 6,693 followersView post →
VD
Views on Drugs
@ViewsOnDrugsBot · X
Classic #serotonergic #psychedelics for mood and depressive symptoms: a #meta-analysis of mood disorder patients and healthy participants https://t.co/t6Q9PTddAg
Jan 16, 2021 · 1 like · 3 shares · 2,055 followersView post →
LP
Lily Aleksandrova, PhD
@NeuroLilyAleks · X
RT @JeromeSarris: The first in-depth #psychedelics meta-analysis for #depression & negative #mood state. We found very promising data... Fu…
Jan 15, 2021 · 9 shares · 523 followersView post →
B
Blossom
@blossomact · X
See which 12 studies were included and learn more about what this study concluded on our website
https://t.co/vIIR5m59tc
This meta-analytic review (2021, n=257) found that psychedelics provide improvements in mood for patients with mood disorders, both short (3h to 1d) and long-term (up to 60 days).
https://t.co/4seWaHiLcK
Jan 15, 2021 · 2 likes · 3,343 followersView post →
MG
maria gonzalez
@mariasgonzalez · X
RT @JeromeSarris: The first in-depth #psychedelics meta-analysis for #depression & negative #mood state. We found very promising data... Fu…
Jan 14, 2021 · 9 shares · 118 followersView post →
MB
Michel Blanc
@Blanc07Michel · X
RT @JeromeSarris: The first in-depth #psychedelics meta-analysis for #depression & negative #mood state. We found very promising data... Fu…
Jan 13, 2021 · 9 shares · 1,664 followersView post →
MH
Michael Hermann
@MichaelManurun9 · X
RT @APRA_bot: Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy par…
Jan 12, 2021 · 2 shares · 580 followersView post →
MM
Michele Metelli
@michelemetelli · X
RT @APRA_bot: Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy par…
Jan 12, 2021 · 2 shares · 802 followersView post →
AA
Amsterdam Psychedelic Research Association (APRA)
@APRAresearch · X
Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants. https://t.co/Zas5ONeMDJ
Jan 12, 2021 · 3 likes · 2 shares · 4,000 followersView post →
AM
A/Prof Carolyn Ee MBBS
@drcarolynee · X
RT @JeromeSarris: The first in-depth #psychedelics meta-analysis for #depression & negative #mood state. We found very promising data... Fu…
Jan 12, 2021 · 9 shares · 2,120 followersView post →
JB
Jacinta Brinsley
@jacintabrinsley · X
RT @JeromeSarris: The first in-depth #psychedelics meta-analysis for #depression & negative #mood state. We found very promising data... Fu…
Jan 12, 2021 · 9 shares · 360 followersView post →
DC
Dr Carrie Thomson-Casey
@habits4happier · X
RT @JeromeSarris: The first in-depth #psychedelics meta-analysis for #depression & negative #mood state. We found very promising data... Fu…
Jan 12, 2021 · 9 shares · 413 followersView post →
S
SystematicReviewBot
@EvidenceRobot · X
RT @JeromeSarris: The first in-depth #psychedelics meta-analysis for #depression & negative #mood state. We found very promising data... Fu…
Jan 11, 2021 · 9 shares · 6,693 followersView post →
JS
Jerome Sarris
@JeromeSarris · X
The first in-depth #psychedelics meta-analysis for #depression & negative #mood state. We found very promising data... Further robust research still needing to occur, with application within a psychotherapeutic framework & adequate medical oversight @MAPS https://t.co/7EtYENJL6j
Jan 11, 2021 · 34 likes · 9 shares · 343 followersView post →
PA
Psychedelic Alpha
@Psyched_Alpha · X
New Research: Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants
https://t.co/3x8Ce0YNO6
Jan 11, 2021 · 2 likes · 20,785 followersView post →
PC
PsychiatryAI.com
@PsychiatryAIcom · X
Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants https://t.co/ndS9oX3uN3