Ageing Res Rev March 2021 PMID 33434685

Monoamine oxidases in age-associated diseases: New perspectives for old enzymes.

Yohan Santin, Jessica Resta, Angelo Parini, Jeanne Mialet-Perez

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Mentions

Peak: 7 in Jan 2021

across 3 sources since Jan 2021

Extended reach

129,834

potential audience

Total likes

Video views

642

Mentions per month

Jan 2021 – Apr 2024

Where it's discussed

X / Twitter9 posts
YouTube3 videos
Facebook2 posts

AI synopsis

What people are saying

The discussions emphasize the role of MAOs in age-related health issues, with posts referencing terms like 'oxidative stress' and 'mitochondrial stress' to underline their relevance. Overall, the tone balances acknowledgment of the research’s importance with curiosity about future applications, which reflects moderate agreement, interest, and perceived impact.

AgreementModerate agreement

Most discussions endorse the significance of MAOs in aging and related diseases, indicating general consensus on their importance.

InterestModerate interest

Participants demonstrate moderate interest, mainly focusing on summaries and key implications rather than detailed critique.

EngagementModerate engagement

Several posts reference specific mechanisms like reactive oxygen species and mitochondrial stress, showing active engagement with the content.

ImpactModerate impact

The discussions highlight potential for new perspectives on treating age-related diseases, suggesting perceived moderate impact.

Abstract in brief

As people live longer, they tend to face more chronic health issues, partially because of the buildup of aging cells that impair organ function, with mitochondrial stress playing a key role.
Monoamine oxidases (MAOs) are enzymes involved in breaking down certain brain chemicals, but recent research shows they also produce reactive oxygen species (ROS) in mitochondria, which can contribute to aging and related diseases both in the brain and other organs.
The review discusses how MAO activity increases in aging tissues and how this may lead to more cell damage through oxidative stress, offering new insights into potential ways to target these enzymes to improve health during aging.]

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All mentions

Type-B Monoamine Oxidase Inhibitors in Neurological Disease Treatment

This video discusses the clinical applications of Type-B monoamine oxidase inhibitors like selegiline, rasagiline, and safinamide, highlighting their neuroprotective effects and potential for treating various…

Яблучанський М.І., доктор медичних наук, професор · Apr 14, 2024 434 views

Selegiline and MAO Inhibitors in Anti-Aging and Neurological Therapy

Aging is a major social challenge, with increased chronic illnesses and healthcare costs. This video explores how MAO inhibitors like selegiline can reduce oxidative stress, protect neurons, and potentially combat…

Яблучанський М.І., доктор медичних наук, професор · Apr 12, 2024 129 views

Type-B Monoamine Oxidase Inhibitors in Neurodegenerative Treatments

Type-B monoamine oxidase inhibitors like selegiline, rasagiline, and safinamide are used to treat Parkinson’s disease. Preclinical research shows they have neuroprotective effects, including reducing oxidative stress…

Яблучанський М.І., доктор медичних наук, професор · Apr 13, 2024 80 views

Kelly A. Hogan Ph.D.

@Loose_Lab_Rat · X

Monoamine oxidases in age-associated diseases: New perspectives for old enzymes https://t.co/mEJz1DlHmB

Mar 28, 2021 · 2,242 followers View post →

Agingdoc

@agingdoc1 · X

Monoamine oxidases in age-associated diseases: New perspectives for old enzymes https://t.co/FLvxwke1Av

Mar 27, 2021 · 2 likes · 41,300 followers View post →

AgeingUK

@AgeingUK · X

RT @AgingBiology: Monoamine oxidases in age-associated diseases: New perspectives for old enzymes https://t.co/IrqmIhkHYD

Jan 21, 2021 · 2 shares · 3,028 followers View post →

Ariakas Enoreth

@Aenoreth · X

RT @AgingBiology: Monoamine oxidases in age-associated diseases: New perspectives for old enzymes https://t.co/IrqmIhkHYD

Jan 19, 2021 · 2 shares · 1,009 followers View post →

Aging Science News

@AgingBiology · X

Monoamine oxidases in age-associated diseases: New perspectives for old enzymes https://t.co/IrqmIhkHYD

Jan 19, 2021 · 7 likes · 2 shares · 30,529 followers View post →

Mitochondrial News

@MitochondriaNe1 · X

#mitochondria Monoamine oxidases in age-associated diseases: New perspectives for old enzymes. https://t.co/cOPzeJpbO9 via @MitochondriaNe1

Jan 13, 2021 · 1 like · 2,256 followers View post →

AgingResearch

@TheAgingField · X

RT @agingdoc1: Monoamine oxidases in age-associated diseases: New perspectives for old enzymes Overview of the major results on the regul…

Jan 13, 2021 · 1 share · 5,271 followers View post →