PubHawk
Int J Mol Sci January 2021 PMID 33440866

α-Pinene Enhances the Anticancer Activity of Natural Killer Cells via ERK/AKT Pathway.

Hantae Jo, Byungsun Cha, Haneul Kim, Sofia Brito, Byeong Mun Kwak, Sung Tae Kim, Bum-Ho Bin, Mi-Gi Lee

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Mentions

6
Peak: 2 in Jun 2024
across 3 sources since Jan 2021

Extended reach

1,842
potential audience

Total likes

2

Video views

15

Mentions per month

Jan 2021 – Jul 2024

Where it's discussed

  • X / Twitter3 posts
  • YouTube2 videos
  • News1 articles

AI synopsis

What people are saying

Discussions highlight the promising role of pinene in cancer therapy, with phrases like 'potential in therapy' and references to natural compound benefits. The tone combines scientific curiosity with optimism, exemplified by mentions of NK cell activation and pathways like ERK/AKT, demonstrating moderate engagement with the research's significance and mechanisms.

AgreementModerate agreement

Most discussions acknowledge the positive potential of pinene in enhancing cancer immunotherapy, reflecting general agreement on its benefits.

InterestHigh interest

Posts demonstrate high interest by referencing biochemical pathways and therapeutic applications, indicating curiosity about the research implications.

EngagementModerate engagement

The mentions include specific comments on NK cell activity and natural compounds, showing moderate depth in engagement with scientific details.

ImpactModerate impact

While some emphasize the significance of herbal compounds in future treatments, others see it as preliminary, leading to a generally moderate perception of immediate impact.

Abstract in brief

  • Pinene enhances the anticancer activity of natural killer (NK) cells by activating the ERK-AKT pathway, increasing the production of key proteins like perforin and granzyme B that help destroy cancer cells.
  • The study showed that pinene not only boosts NK cell activity in laboratory cell lines but also reduces tumor growth in mice, indicating its potential as a cancer immunotherapy agent.
  • Overall, the research suggests that pinene could be used to activate immune cells to better fight cancer, highlighting its promise in future cancer treatment strategies.]
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Top posts

Most liked on X and Bluesky
NK papers
@NK_papers · X

α-Pinene Enhances the Anticancer Activity of Natural Killer Cells via ERK/AKT Pathway. by Jo H, Cha B, Kim H, Brito S, Kwak BM, Kim ST, Bin BH, Lee MG https://t.co/h9FUEI9mdh

Jan 15, 2021 · 1,286 followers View post →
Natural Life
@LiveNatural_ · X

Go into the forest and talk to the trees. https://t.co/QtXYw4y1x0 https://t.co/dE0UuAquhI

Jul 7, 2024 · 307 followers View post →

All mentions

Natural Life
@LiveNatural_ · X

Go into the forest and talk to the trees. https://t.co/QtXYw4y1x0 https://t.co/dE0UuAquhI

Jul 7, 2024 · 307 followers View post →
Krzysztof Kurpiecki
@Reition_com · X

Powietrze w lesie pełne jest alfa pinenu #fitoncydy. Szczególnie wokół jałowców czy sosen. Badania dowodzą że aktywuje on komórki NK co może mieć zastosowanie w terapiach antyrakowych. Badania: https://t.co/yzC7z35hyF Więcej o leśnych fitoncydach: https://t.co/NQDTJzKTU9 https://t.co/PUO7di1Auq

Mar 26, 2021 · 225 followers View post →
NK papers
@NK_papers · X

α-Pinene Enhances the Anticancer Activity of Natural Killer Cells via ERK/AKT Pathway. by Jo H, Cha B, Kim H, Brito S, Kwak BM, Kim ST, Bin BH, Lee MG https://t.co/h9FUEI9mdh

Jan 15, 2021 · 1,286 followers View post →
Phytoncides and Immunity From Forest To Facilit 2024 ...
News

effects of a forest environment on natural killer cells in humans: an observational https://doi.org/10.3390/ijms22020656. pilot study, Oncotarget 23 (2018) ...

Dec 14, 2025 View →