March 2021 PMID 33476422

Accelerated long-term forgetting in focal epilepsy: Do interictal spikes during sleep matter?

Isabelle Lambert, Eve Tramoni-Negre, Stanislas Lagarde, Francesca Pizzo, Agnès Trebuchon-Da Fonseca, Fabrice Bartolomei, Olivier Felician

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Mentions

18
Peak: 10 in Jan 2021
across 3 sources since Jan 2021

Extended reach

23,947
potential audience

Total likes

27

Video views

59

Mentions per month

Jan 2021 – Nov 2023

Where it's discussed

  • X / Twitter15 posts
  • News2 articles
  • YouTube1 videos

AI synopsis

What people are saying

The discussions reflect a moderate interest level, with posts supporting the idea that interictal spikes during sleep contribute to memory issues, as seen in phrases like 'may disrupt memory consolidation' and 'mechanism through which spiking causes forgetting.' The tone is generally respectful and curious, indicating recognition of the study's relevance but not intense controversy or critique.

AgreementModerate agreement

Most discussions acknowledge the importance of the findings, with some explicitly supporting the idea that interictal spikes during sleep play a role in memory disruption.

InterestModerate interest

Participants show moderate interest, frequently referencing the mechanisms and implications of the research, but without deep technical analysis.

EngagementModerate engagement

The discussions involve some level of engagement, including mentions of related concepts like sleep stages and epilepsy, but lack extensive detailed debate or critique.

ImpactModerate impact

The tweets suggest that the publication influences ongoing conversations about epilepsy and sleep, indicating a moderate perceived significance.

Abstract in brief

  • Accelerated long-term forgetting (ALF) is a type of amnesia commonly seen in patients with focal epilepsy, especially temporal lobe epilepsy, affecting the consolidation of declarative memories.
  • The exact mechanisms behind ALF are unclear, with ongoing debates about factors like brain lesions, seizures, interictal discharges, and sleep's roles in this memory loss.
  • The authors offer a new model based on recent brain activity recordings that explains how interictal spikes during wakefulness and sleep contribute to the development of ALF across different timescales.

Top posts

Most liked on X and Bluesky
Epilepsia
@EpilepsiaJourn · X

Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/pTzzwloFxi CRITICAL REVIEW – INVITED COMMENTARY #epilepsy #ALF #NREMsleep @IlaeWeb @wileyneurosci https://t.co/LCUYdvLN2A

Jan 22, 2021 · 17 likes · 8 shares · 10,307 followers View post →
Luke Tomycz, MD
@BrainSurgeonLT · X

Lambert et al. suggests that interictal epileptiform discharges may lead to disruption of memory consolidation in NREM sleep. This may be a mechanism through which interictal spiking within mesial temporal areas causes accelerated long-term forgetting. https://t.co/Y99udxDwag

May 18, 2021 · 7 likes · 1 share · 461 followers View post →
Stéphane Auvin
@stephane_auvin · X

Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? - Lambert - Epilepsia https://t.co/uzZNLiZaq6

Jan 30, 2021 · 3 likes · 1 share · 2,045 followers View post →
Roxana Flores A. MD,PhD
@flo_rox · X

RT @EpilepsiaJourn: Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/pTzzwloFxi…

Jan 22, 2021 · 8 shares · 2,152 followers View post →
Neuropediatrics®️
@NeuroInfanti · X

Accelerated long-term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/fJA2FaIhXl

Jan 25, 2021 · 2,077 followers View post →
Marcus Ng
@spikewhisperer · X

RT @EpilepsiaJourn: Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/pTzzwloFxi…

Jan 22, 2021 · 8 shares · 1,448 followers View post →

All mentions

Sleep
@Sleep20746524 · X

Accelerated long-term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/q5MSF6wTJ5

Sep 22, 2021 · 342 followers View post →
Joseph Samuel Peedicail
@josephpeedicail · X

https://t.co/8uAqbGGXlp

May 19, 2021 · 72 followers View post →
Jeff Sica
@sica_jeff · X

RT @BrainSurgeonLT: Lambert et al. suggests that interictal epileptiform discharges may lead to disruption of memory consolidation in NREM…

May 18, 2021 · 1 share · 25 followers View post →
Luke Tomycz, MD
@BrainSurgeonLT · X

Lambert et al. suggests that interictal epileptiform discharges may lead to disruption of memory consolidation in NREM sleep. This may be a mechanism through which interictal spiking within mesial temporal areas causes accelerated long-term forgetting. https://t.co/Y99udxDwag

May 18, 2021 · 7 likes · 1 share · 461 followers View post →
Sebastian Ortiz, MD
@Sebasortizdelar · X

RT @EpilepsiaJourn: Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/pTzzwloFxi…

Feb 1, 2021 · 8 shares · 1,414 followers View post →
Marcus Ng
@spikewhisperer · X

RT @stephane_auvin: Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? - Lambert - Epilepsia ht…

Jan 31, 2021 · 1 share · 1,448 followers View post →
Stéphane Auvin
@stephane_auvin · X

Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? - Lambert - Epilepsia https://t.co/uzZNLiZaq6

Jan 30, 2021 · 3 likes · 1 share · 2,045 followers View post →
Neuropediatrics®️
@NeuroInfanti · X

Accelerated long-term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/fJA2FaIhXl

Jan 25, 2021 · 2,077 followers View post →
Rodrigo Riquelme C
@dr_rodryr · X

RT @EpilepsiaJourn: Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/pTzzwloFxi…

Jan 23, 2021 · 8 shares · 225 followers View post →
Yamile Calle-Lopez
@CalleYamile · X

RT @EpilepsiaJourn: Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/pTzzwloFxi…

Jan 23, 2021 · 8 shares · 987 followers View post →
Marcus Ng
@spikewhisperer · X

RT @EpilepsiaJourn: Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/pTzzwloFxi…

Jan 22, 2021 · 8 shares · 1,448 followers View post →
Roxana Flores A. MD,PhD
@flo_rox · X

RT @EpilepsiaJourn: Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/pTzzwloFxi…

Jan 22, 2021 · 8 shares · 2,152 followers View post →
S.A.
@SalmanAssad1 · X

RT @EpilepsiaJourn: Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/pTzzwloFxi…

Jan 22, 2021 · 8 shares · 765 followers View post →
Epilepsia
@EpilepsiaJourn · X

Accelerated long‐term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/pTzzwloFxi CRITICAL REVIEW – INVITED COMMENTARY #epilepsy #ALF #NREMsleep @IlaeWeb @wileyneurosci https://t.co/LCUYdvLN2A

Jan 22, 2021 · 17 likes · 8 shares · 10,307 followers View post →
Damian Williams
@damianjwilliams · X

Accelerated long-term forgetting in focal epilepsy: Do interictal spikes during sleep matter? https://t.co/fMh9VaP6Jv via @circleboom

Jan 21, 2021 · 1 followers View post →