Science January 2021 PMID 33479150

Convergent evolution of pain-inducing defensive venom components in spitting cobras.

T D Kazandjian, D Petras, S D Robinson, J van Thiel, H W Greene, K Arbuckle, A Barlow, D A Carter, R M Wouters, G Whiteley, S C Wagstaff, A S Arias, L-O Albulescu, A Plettenberg Laing, C Hall

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Mentions

134
Peak: 25 in Jan 2021
across 6 sources since Jul 2020

Extended reach

747,278
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6,111

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Jul 2020 – Feb 2024

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AI synopsis

What people are saying

The discussions contain multiple references to the evolutionary significance of spitting cobras, with posts noting how the ability to spit venom evolved independently in different lineages as a defense mechanism. Phrases like 'pumped to read this paper' and 'fascinating example of convergent evolution' highlight excitement and a strong connection to the topic, signaling how the language and tone used contribute to a vibrant exchange of ideas around the publication.

AgreementModerate agreement

Most participants express support for the findings of the publication, acknowledging the significance of the research on spitting cobras.

InterestHigh interest

The discussions reveal a high level of curiosity and relevance, with many users engaging deeply with the topic.

EngagementHigh engagement

Several participants reference specific aspects of the research, such as the role of phospholipase A toxins, indicating a thorough engagement with the material.

ImpactHigh impact

Contributors believe the publication has substantial implications for understanding evolutionary biology and venom development.

Abstract in brief

  • The study examines how three different lineages of spitting cobras have independently developed the ability to spit venom as a defensive mechanism, showcasing convergent evolution in response to environmental pressures.
  • The research highlights the role of specific phospholipase A (PLA) toxins in these species, which enhance the effectiveness of existing venom components by activating pain receptors in mammals.
  • This case exemplifies how evolutionary changes can arise in separate lineages due to similar selective pressures, illustrating the complex relationship between diet, defense, and venom evolution in snakes.

Top posts

Most liked on X and Bluesky
ツイ鳥「ジョージ=コクム」(森に入ったのですが怪物もおらず、ツイ鳥だけがいました。赤字貿易経営者!
@_596_ · X

そんなこんなでサックリ話していきましたが、 こういうコブラもいるということですね。 ポイズンガンの使い手ですね、きっと。 あとは適当に論文置いておくので良ければどーぞ。 引用元1:Convergent evolution of pain-inducing defensive venom components in spitting - https://t.co/Dob4r5N82P

Feb 7, 2024 · 57 likes · 3 shares · 127,406 followers View post →
SciShow
@SciShow · X

If you spook a spitting cobra, it might literally shoot venom at your eyes! And it seems like our ancestors caused them to evolve this bizarre ability. https://t.co/mZw2bniVbs https://t.co/ONsGeoevAo

Jun 30, 2021 · 21 likes · 3 shares · 115,464 followers View post →
Marianna Karageorgi
@m_karageorgi · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/yLOWQbO9mE

Jan 23, 2021 · 16 likes · 4 shares · 519 followers View post →
Álvaro Martínez del Pozo
@mart1nezdelp0z0 · X

Tercera vez que los venenos son portada de Science, en 4 años. ¿Quién dijo que era un tema de bajo impacto? La Subdirección General de Proyectos. Curioso... Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/VIboEUw3WF

Jan 22, 2021 · 12 likes · 2 shares · 841 followers View post →
Liam Revell
@phytools_liam · X

More #phytools (& other) #Rstats plotting methods in this @TalineKaz et al. Lower EC50 value = more potent venom, so I think the contMap color scheme is appropriate. Full article: https://t.co/O5CVBMjNtu. https://t.co/1u5Cd9hpUg

Mar 6, 2021 · 9 likes · 2 shares · 10,114 followers View post →
Ronald Jenner
@evolriffs · X

Friday digital journal club with awesome work done by @TalineKaz @richardharris27 @Venom__Doc @nickcasewell @wolfgangwuster and colleagues: Evolutionary CSI: fishing for venom targets https://t.co/YXTJP1nBol via @YouTube

Jan 28, 2022 · 7 likes · 2 shares · 694 followers View post →

All mentions

釣りか肉を焼く人(趣味のたつ)
@shumitatsu_x · X

RT @_596_: そんなこんなでサックリ話していきましたが、 こういうコブラもいるということですね。 ポイズンガンの使い手ですね、きっと。 あとは適当に論文置いておくので良ければどーぞ。 引用元1:Convergent evolution of pain-inducin…

Feb 7, 2024 · 3 shares · 152 followers View post →
井戸端会議
@kokugo_shakai · X

RT @_596_: そんなこんなでサックリ話していきましたが、 こういうコブラもいるということですね。 ポイズンガンの使い手ですね、きっと。 あとは適当に論文置いておくので良ければどーぞ。 引用元1:Convergent evolution of pain-inducin…

Feb 7, 2024 · 3 shares · 3,898 followers View post →
36号
@World1Cat · X

RT @_596_: そんなこんなでサックリ話していきましたが、 こういうコブラもいるということですね。 ポイズンガンの使い手ですね、きっと。 あとは適当に論文置いておくので良ければどーぞ。 引用元1:Convergent evolution of pain-inducin…

Feb 7, 2024 · 3 shares · 294 followers View post →
ツイ鳥「ジョージ=コクム」(森に入ったのですが怪物もおらず、ツイ鳥だけがいました。赤字貿易経営者!
@_596_ · X

そんなこんなでサックリ話していきましたが、 こういうコブラもいるということですね。 ポイズンガンの使い手ですね、きっと。 あとは適当に論文置いておくので良ければどーぞ。 引用元1:Convergent evolution of pain-inducing defensive venom components in spitting - https://t.co/Dob4r5N82P

Feb 7, 2024 · 57 likes · 3 shares · 127,406 followers View post →
Bruja
@lyssasphere · X

oh whoops here https://t.co/8IqOWrTtop

Oct 23, 2023 · 2 likes · 47,241 followers View post →
Merdle Dwight Hamlock
@MDhamlock · X

@Katacombz https://t.co/gd2t37iFIp

Jul 7, 2023 · 1 like · 222 followers View post →
Neil van der Linden (hij/hem, he/him)
@NeilvanderLind1 · X

Convergent evolution provides insights into the selective drivers underlying evolutionary change. Snake venoms, with a direct genetic basis and clearly defined functional phenotype, provide a model system for exploring the repeated evolution of adaptations https://t.co/AtvnykHBBQ https://t.co/VzGdZNxkaD

Feb 12, 2023 · 815 followers View post →
dutrte
@dutrtemodi · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras | Science https://t.co/EO1H6UNAkS https://t.co/TNvmzxBn2k

Oct 21, 2022 · 714 followers View post →
インターネットやめろ
@wywvwyw · X

Venom: made corrections ← Previous revision Revision as of 01:20, 31 August 2022 Line 31: Line 31: A recent study<ref name=Kazandjian>{{cite journal|last=Kazandjian|first=TD|title=Convergent evolution of pain-inducing defensive venom components in spitting c…

Aug 30, 2022 · 353 followers View post →
Adam Ramsay
@AdamRamsay · X

RT @mhuzzell: @AdamRamsay "Like a predatory snake spitting venom" seems like a particularly apt metaphor given that that behaviour appears…

Apr 14, 2022 · 1 share · 26,972 followers View post →
Molly (parody account)
@mhuzzell · X

@AdamRamsay "Like a predatory snake spitting venom" seems like a particularly apt metaphor given that that behaviour appears to have evolved specifically in order to blind/deter/incapacitate humans. https://t.co/RdJD9LZ7xT

Apr 14, 2022 · 1 share · 262 followers View post →
Richard Harris
@richardharris27 · X

RT @evolriffs: Friday digital journal club with awesome work done by @TalineKaz @richardharris27 @Venom__Doc @nickcasewell @wolfgangwuster…

Jan 28, 2022 · 2 shares · 518 followers View post →
Nick Casewell
@nickcasewell · X

RT @evolriffs: Friday digital journal club with awesome work done by @TalineKaz @richardharris27 @Venom__Doc @nickcasewell @wolfgangwuster…

Jan 28, 2022 · 2 shares · 1,716 followers View post →
Ronald Jenner
@evolriffs · X

Friday digital journal club with awesome work done by @TalineKaz @richardharris27 @Venom__Doc @nickcasewell @wolfgangwuster and colleagues: Evolutionary CSI: fishing for venom targets https://t.co/YXTJP1nBol via @YouTube

Jan 28, 2022 · 7 likes · 2 shares · 694 followers View post →
Centre for Snakebite Research & Interventions
@CSRIatLSTM · X

RT @phylophile: @SwanseaUni @swanscience Revisiting the coverage of our previous research (with @wolfgangwuster and @TheMCfarmer) for #Worl…

Jul 16, 2021 · 2 shares · 1,772 followers View post →
Joel McGlothlin
@joelmcglothlin · X

RT @phylophile: @SwanseaUni @swanscience Revisiting the coverage of our previous research (with @wolfgangwuster and @TheMCfarmer) for #Worl…

Jul 16, 2021 · 2 shares · 8,493 followers View post →
Kevin Arbuckle
@phylophile · X

@SwanseaUni @swanscience Revisiting the coverage of our previous research (with @wolfgangwuster and @TheMCfarmer) for #WorldSnakeDay. See also a summary of an extension of this idea looking at defensive evolution of venom in spitting cobras: https://t.co/7O0ldLnOKp (paper here: https://t.co/8otgOJOa9C)

Jul 16, 2021 · 3 likes · 2 shares · 923 followers View post →
Luca
@SorrisoCattivo · X

https://t.co/SjSmhOVZrG

Jul 11, 2021 · 142 followers View post →
Shipwreck
@markthesnark2 · X

https://t.co/Rgu3iyAVJP @stevensongs It's a spitter

Jul 2, 2021 · 3,697 followers View post →
Eadwine Molanoix
@EadMolanoix · X

https://t.co/gIR1cQ0U5f

Jul 1, 2021 · 1 like · 352 followers View post →
William Wallace
@bill14051 · X

RT @SciShow: If you spook a spitting cobra, it might literally shoot venom at your eyes! And it seems like our ancestors caused them to evo…

Jun 30, 2021 · 3 shares · 332 followers View post →
Marcus didius falco
@falcos2012 · X

RT @SciShow: If you spook a spitting cobra, it might literally shoot venom at your eyes! And it seems like our ancestors caused them to evo…

Jun 30, 2021 · 3 shares · 880 followers View post →
Тэ дрэвэт утвикλэрэн
@TeaDrivenDev · X

RT @SciShow: If you spook a spitting cobra, it might literally shoot venom at your eyes! And it seems like our ancestors caused them to evo…

Jun 30, 2021 · 3 shares · 943 followers View post →
SciShow
@SciShow · X

If you spook a spitting cobra, it might literally shoot venom at your eyes! And it seems like our ancestors caused them to evolve this bizarre ability. https://t.co/mZw2bniVbs https://t.co/ONsGeoevAo

Jun 30, 2021 · 21 likes · 3 shares · 115,464 followers View post →
Hogan
@Hogan698 · X

Lots of news about spitting cobras recently. @AlongsideWild Just posted something the other day that got me curious about them, then this video just came up. Fun coincidence. https://t.co/XPaQg1BSF9

Jun 30, 2021 · 1 like · 6,898 followers View post →
Ross White-Chinnery
@RWChinnery · X

TIL spitting cobras evolved independently three times. In each instance shortly after a certain genus of bipedal primates entered their neighborhood @SnakeDiscovery https://t.co/Wqh7PlEDH8 #snakes #snek #dangernoodle #cautionramen #heck

Jun 29, 2021 · 98 followers View post →
e-csce
@e_csce · X

How These Snakes Evolved to Spit… IN YOUR EYE @ https://t.co/OdMKm8hqia https://t.co/pdHXTA5xRq

Jun 29, 2021 · 117 followers View post →
Kitty
@kittybravofan · X

How These Snakes Evolved to Spit… IN YOUR EYE https://t.co/XusygSzzci via @YouTube

Jun 29, 2021 · 720 followers View post →
Johannes Lüke
@JohannesSLueke · X

New video by SciShow: How These Snakes Evolved to Spit… IN YOUR EYE https://t.co/ckdLE15K3p

Jun 29, 2021 · 83 followers View post →
R Tweets
@rstats_tweets · X

RT @phytools_liam: More #phytools (& other) #Rstats plotting methods in this @TalineKaz et al. Lower EC50 value = more potent venom, so I t…

Mar 6, 2021 · 2 shares · 4,213 followers View post →
Rstats
@rstatstweet · X

RT @phytools_liam: More #phytools (& other) #Rstats plotting methods in this @TalineKaz et al. Lower EC50 value = more potent venom, so I t…

Mar 6, 2021 · 2 shares · 28,804 followers View post →
Liam Revell
@phytools_liam · X

More #phytools (& other) #Rstats plotting methods in this @TalineKaz et al. Lower EC50 value = more potent venom, so I think the contMap color scheme is appropriate. Full article: https://t.co/O5CVBMjNtu. https://t.co/1u5Cd9hpUg

Mar 6, 2021 · 9 likes · 2 shares · 10,114 followers View post →
Diksha Bhalla
@dbhalla5 · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/okXNbRTfJo

Feb 6, 2021 · 22 followers View post →
Yukinari Igita
@yukinari230 · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/G5jq0F8Mwr

Feb 6, 2021 · 1,298 followers View post →
Mehdi Beniddir
@BeniddirM · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/eVRdRTtIcu

Jan 28, 2021 · 2,091 followers View post →
Jamshid, MD
@jamykshema · X

Up-regulation of phospholipase A2 (PLA2) toxins, which potentiate the action of preexisting venom cytotoxins to activate mammalian sensory neurons and cause enhanced pain. Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/mXb9mhIoeJ

Jan 27, 2021 · 430 followers View post →
Jente Ottenburghs | Avian Hybrids
@Jente_O · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras | Science https://t.co/T41f19dlVy

Jan 25, 2021 · 4,045 followers View post →
Squid News
@SquidNews1 · X

From offense to defenseVenom in snakes is largely used to subdue and/or kill prey, and most venoms have... https://t.co/zj9V8Wj2mA

Jan 24, 2021 · 19 followers View post →
Healthy Carelife
@morning_news24h · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras ... https://t.co/m5WBv8XaRo https://t.co/yLxi0lXRk1

Jan 24, 2021 · 865 followers View post →
Thomas B
@LabPigeon · X

RT @m_karageorgi: Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/yLOWQbO9mE

Jan 24, 2021 · 4 shares · 822 followers View post →
Ishmail Abdus-Saboor
@IshmailSaboor · X

RT @m_karageorgi: Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/yLOWQbO9mE

Jan 24, 2021 · 4 shares · 20,753 followers View post →
C. Brandon Ogbunu
@big_data_kane · X

RT @m_karageorgi: Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/yLOWQbO9mE

Jan 24, 2021 · 4 shares · 8,482 followers View post →
Marianna Karageorgi
@m_karageorgi · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/yLOWQbO9mE

Jan 23, 2021 · 16 likes · 4 shares · 519 followers View post →
Snakebite Publications
@SnakePubs · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras. https://t.co/njpNebucix

Jan 23, 2021 · 995 followers View post →
幼蛇
@carnivoralist · X

表紙の論文。要旨見ると、毒を防御に用いるドクフキコブラの系統において、毒の組成がより哺乳類(捕食者)にとって痛みを感じさせるように変化してきた、といった内容?あとで読も。 Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/4jSk09KD6N

Jan 22, 2021 · 6 likes · 1,081 followers View post →
Sara García Linares
@SaraGLinares · X

RT @mart1nezdelp0z0: Tercera vez que los venenos son portada de Science, en 4 años. ¿Quién dijo que era un tema de bajo impacto? La Subdire…

Jan 22, 2021 · 2 shares · 462 followers View post →
Belen Yelamos Lopez
@BYelamos · X

RT @mart1nezdelp0z0: Tercera vez que los venenos son portada de Science, en 4 años. ¿Quién dijo que era un tema de bajo impacto? La Subdire…

Jan 22, 2021 · 2 shares · 151 followers View post →
Álvaro Martínez del Pozo
@mart1nezdelp0z0 · X

Tercera vez que los venenos son portada de Science, en 4 años. ¿Quién dijo que era un tema de bajo impacto? La Subdirección General de Proyectos. Curioso... Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/VIboEUw3WF

Jan 22, 2021 · 12 likes · 2 shares · 841 followers View post →
Kawai_Yusuke
@fiddler_K · X

[メモ]防御手段として毒を吐く行動は、コブラの中で3回独立して進化している。吐かれる毒の成分は哺乳類の感覚神経に作用し痛みを増大させるように収歛している/Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/fdkWuTvuzK

Jan 22, 2021 · 1 share · 350 followers View post →
Department of Biosciences, University of Oslo
@biovitenskap · X

Gratulerer med ny publikasjon i dag @EivindUndheim et al. «Convergent Evolution of Pain-Inducing Defensive Venom Components in Spitting Cobras» fra @biovitenskap @CEESUiO @unioslo_mn @UniOslo! https://t.co/DVnEYupsKv

Jan 22, 2021 · 1,566 followers View post →
Paul Hoskisson
@PaulHoskisson · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras #Papers365 https://t.co/AKxMxJEeHt

Jan 22, 2021 · 2 likes · 9,218 followers View post →
Gunnar
@evolveon · X

"...repeated independent changes provide a fascinating example of convergent evolution across multiple phenotypic levels driven..." Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/wfBQo0dAjG #science #biology #zoology

Jan 22, 2021 · 432 followers View post →
Milton Tan
@mtanichthys · X

RT @DaniDrabeck: So pumped to read this paper showing the importance of defense as a strong selection pressure in #venom evolution!!!! Conv…

Jan 21, 2021 · 1 share · 5,094 followers View post →
Danielle Drabeck
@DaniDrabeck · X

So pumped to read this paper showing the importance of defense as a strong selection pressure in #venom evolution!!!! Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/eBix3Lr92x

Jan 21, 2021 · 1 share · 363 followers View post →
Storm Bear - I design spaceships. Be jealous!
@StormBear · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras - Science Magazine https://t.co/aeVwnyiaXA #science https://t.co/Jvl8sv7TCP

Jan 21, 2021 · 1,094 followers View post →
Light-Yagami
@LightYa33625392 · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/TTNPaGJbQL

Jan 21, 2021 · 23 followers View post →
norah fernandez
@norahlfy · X

RT @scipak_es: El veneno inductor de dolor de diferentes linajes de cobra escupidora evolucionó como defensa https://t.co/LcoUkeCCUG https:…

Jan 21, 2021 · 1 share · 979 followers View post →
@scipak_es
@scipak_es · X

El veneno inductor de dolor de diferentes linajes de cobra escupidora evolucionó como defensa https://t.co/LcoUkeCCUG https://t.co/i940XyFIph

Jan 21, 2021 · 1 share · 2,508 followers View post →
Sairam Jabba
@SairamJabba · X

Convergent evolution of pain-inducing defensive venom components in spitting cobras https://t.co/7w8RUz7MdS

Jan 21, 2021 · 1 like · 468 followers View post →
Snakebite
@DrSnakeVenom · X

RT @biorxivpreprint: Convergent Evolution of Pain-Inducing Defensive Venom Components in Spitting Cobras https://t.co/s8k4jZ0AfB #bioRxiv

Jul 13, 2020 · 1 share · 729 followers View post →
bioRxiv Evobio
@biorxiv_evobio · X

Convergent Evolution of Pain-Inducing Defensive Venom Components in Spitting Cobras https://t.co/EI9sfgPJaE #biorxiv_evobio

Jul 11, 2020 · 4,458 followers View post →
bioRxiv
@biorxivpreprint · X

Convergent Evolution of Pain-Inducing Defensive Venom Components in Spitting Cobras https://t.co/s8k4jZ0AfB #bioRxiv

Jul 11, 2020 · 6 likes · 1 share · 137,554 followers View post →