PubHawk
June 2021 PMID 33480671

Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered Lipid Nanoparticles.

Uri Elia, Srinivas Ramishetti, Ronit Rosenfeld, Niels Dammes, Erez Bar-Haim, Gonna Somu Naidu, Efi Makdasi, Yfat Yahalom-Ronen, Hadas Tamir, Nir Paran, Ofer Cohen, Dan Peer

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Mentions

28
Peak: 9 in Jan 2021
across 5 sources since Jan 2021

Extended reach

75,631
potential audience

Total likes

224

Video views

2,913

Mentions per month

Jan 2021 – Nov 2021

Where it's discussed

  • X / Twitter19 posts
  • News3 articles
  • YouTube2 videos
  • Reddit2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The collective discussions highlight the significance of vaccine design leveraging lipid nanoparticles and the immune responses observed, such as neutralizing antibodies, demonstrating a keen scientific interest. The tone balances technical detail with cautious optimism, indicating both engagement with the implications and acknowledgment of ongoing debates around nanoparticle safety and vaccine efficacy.

AgreementModerate agreement

Most discussions recognize the significance of the vaccine design and its potential for effective immune responses, showing a general consensus of support.

InterestModerate interest

Participants display moderate interest, engaging with technical details like lipid nanoparticles and immune responses, though some remain cautious or inquisitive.

EngagementModerate engagement

Comments include references to immune mechanisms, such as neutralizing antibodies and Th1 responses, indicating active engagement with the scientific content.

ImpactModerate impact

The discussions suggest that the research could influence future vaccine development and public health strategies, reflecting a moderate impact outlook.

Abstract in brief

  • SARS-CoV-2 is the virus responsible for COVID-19, which has caused over a million deaths globally, highlighting the urgent need for a vaccine.
  • Researchers are developing mRNA vaccines as a fast and effective approach, utilizing lipid nanoparticles to deliver the vaccine's key protein component.
  • In animal studies, the mRNA vaccine induced a strong immune response, suggesting that this platform is a promising option for creating effective COVID-19 vaccines.
Read the full abstract

Top posts

Most liked on X and Bluesky
Dan Peer
@peer_lab · X

We are proud to share our latest contribution to the #Covid_19 mRNA vaccine field. A #SARSCoV2-hFc-Conjugated RBD mRNA Vaccine Delivered via Lipid Nanoparticles @acsnano. https://t.co/yRbrEoehZJ

Jan 25, 2021 · 27 likes · 3 shares · 1,849 followers View post →
Oezguer Yalcin
@OezguerYalcin · X

@RolandBakerIII @batmulder @JHorrn @UK_Centrist @EllieJellie2020 @RicardLopez123 @Parsifaler @w_mccairn Following work may give some idea: https://t.co/l9ynHfLr77

Mar 9, 2021 · 4 likes · 2 shares · 260 followers View post →
John Bohórquez
@Johnbo100 · X

Una interesante disertación del Dr. Juan José Arango acerca de la preocupación existente sobre las nanopartículas lipídicas en las vacunas con RNAm, las de Pfizer y Moderna.

Mar 22, 2021 · 1 like · 2 shares · 5,343 followers View post →
Juan José Arango E.
@jjarangoes · X

https://t.co/SlmDb76Xbt

Mar 26, 2021 · 1 like · 2,682 followers View post →
TJ, #FullMetaJacket
@coristus · X

@TrollTemporary @YPotjer Een wat meer technische studie: https://t.co/f4bhaOokiV

Nov 5, 2021 · 1 like · 2,439 followers View post →
JAReglaNava
@ja_regla · X

El diseño de una nueva vacuna basada en mRNA de RBD-hFc de SARS-CoV-2 deliberada en nano partículas de lípidos muestra una robusta respuesta inmune. Esta origina anticuerpos neutralizantes y respuesta Th1 en ratones BALB/c. | ACS Nano https://t.co/fGohYwGAhh

Jan 26, 2021 · 1 like · 2 shares · 1,590 followers View post →

All mentions

Adam Karaba
@KarabaAdam · X

@DuseLu @FilipovLukas @VojtechGibis A k tem LPN formulated lucipherase je jeden článek např zde v časopise od ACS: Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles https://t.co/3FTYCkF1gc

Nov 12, 2021 · 255 followers View post →
TJ, #FullMetaJacket
@coristus · X

@TrollTemporary @YPotjer Een wat meer technische studie: https://t.co/f4bhaOokiV

Nov 5, 2021 · 1 like · 2,439 followers View post →
Frans (Victor Hugo)
@FransPietersma · X

RT @OezguerYalcin: @RolandBakerIII @batmulder @JHorrn @UK_Centrist @EllieJellie2020 @RicardLopez123 @Parsifaler @w_mccairn Following work m…

May 22, 2021 · 2 shares · 2,684 followers View post →
Juan José Arango E.
@jjarangoes · X

https://t.co/SlmDb76Xbt

Mar 26, 2021 · 1 like · 2,682 followers View post →
EL EQUILIBRISTA
@Carlosballen6 · X

RT @Johnbo100: Una interesante disertación del Dr. Juan José Arango acerca de la preocupación existente sobre las nanopartículas lipídicas…

Mar 23, 2021 · 2 shares · 1,519 followers View post →
Jairo Morales Cruz
@jairo_a_morales · X

RT @Johnbo100: Una interesante disertación del Dr. Juan José Arango acerca de la preocupación existente sobre las nanopartículas lipídicas…

Mar 22, 2021 · 2 shares · 613 followers View post →
John Bohórquez
@Johnbo100 · X

Una interesante disertación del Dr. Juan José Arango acerca de la preocupación existente sobre las nanopartículas lipídicas en las vacunas con RNAm, las de Pfizer y Moderna.

Mar 22, 2021 · 1 like · 2 shares · 5,343 followers View post →
Alejandro Vivanco
@Papinacate · X

¿DUDA DE LAS VACUNAS? │ NO DEBERÍA https://t.co/Exg2EECKfr vía @YouTube

Mar 22, 2021 · 479 followers View post →
Juan José Arango E.
@jjarangoes · X

¿DUDA DE LAS VACUNAS? │ NO DEBERÍA es el nombre del último video que he subido a mi canal de YouTube, jjarango2. https://t.co/y6n3Jilcic

Mar 22, 2021 · 2,682 followers View post →
Oezguer Yalcin
@OezguerYalcin · X

@RolandBakerIII @batmulder @JHorrn @UK_Centrist @EllieJellie2020 @RicardLopez123 @Parsifaler @w_mccairn Following work may give some idea: https://t.co/l9ynHfLr77

Mar 9, 2021 · 4 likes · 2 shares · 260 followers View post →
Marta Cabello
@martona_to · X

RT @ja_regla: El diseño de una nueva vacuna basada en mRNA de RBD-hFc de SARS-CoV-2 deliberada en nano partículas de lípidos muestra una ro…

Jan 26, 2021 · 2 shares · 2,807 followers View post →
Gary Beane
@pollinus66 · X

RT @ja_regla: El diseño de una nueva vacuna basada en mRNA de RBD-hFc de SARS-CoV-2 deliberada en nano partículas de lípidos muestra una ro…

Jan 26, 2021 · 2 shares · 2,023 followers View post →
JAReglaNava
@ja_regla · X

El diseño de una nueva vacuna basada en mRNA de RBD-hFc de SARS-CoV-2 deliberada en nano partículas de lípidos muestra una robusta respuesta inmune. Esta origina anticuerpos neutralizantes y respuesta Th1 en ratones BALB/c. | ACS Nano https://t.co/fGohYwGAhh

Jan 26, 2021 · 1 like · 2 shares · 1,590 followers View post →
Maya_Avraham
@MayaAvraham4 · X

RT @peer_lab: We are proud to share our latest contribution to the #Covid_19 mRNA vaccine field. A #SARSCoV2-hFc-Conjugated RBD mRNA Vacc…

Jan 26, 2021 · 3 shares · 39 followers View post →
ACS Nano
@acsnano · X

RT @peer_lab: We are proud to share our latest contribution to the #Covid_19 mRNA vaccine field. A #SARSCoV2-hFc-Conjugated RBD mRNA Vacc…

Jan 25, 2021 · 3 shares · 42,323 followers View post →
Gary Beane
@pollinus66 · X

RT @peer_lab: We are proud to share our latest contribution to the #Covid_19 mRNA vaccine field. A #SARSCoV2-hFc-Conjugated RBD mRNA Vacc…

Jan 25, 2021 · 3 shares · 2,023 followers View post →
Dan Peer
@peer_lab · X

We are proud to share our latest contribution to the #Covid_19 mRNA vaccine field. A #SARSCoV2-hFc-Conjugated RBD mRNA Vaccine Delivered via Lipid Nanoparticles @acsnano. https://t.co/yRbrEoehZJ

Jan 25, 2021 · 27 likes · 3 shares · 1,849 followers View post →
CellFree Sciences
@CFSciences · X

More on #SARSCoV2 and mRNA #vaccine development: Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles https://t.co/wAUqoNqKdw https://t.co/YefgHZEWA0

Jan 24, 2021 · 497 followers View post →
MyJournals
@myjournals · X

[ASAP] Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles https://t.co/MosqhSuLnR

Jan 22, 2021 · 556 followers View post →