Biomed Pharmacother May 2021 PMID 33517191

Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia.

Danlan Fu, Junfei Huang, Kaitao Li, Yuxin Chen, Ye He, Yang Sun, Yilong Guo, Lijuan Du, Qian Qu, Yong Miao, Zhiqi Hu

Mentions

5
Peak: 1 in Nov 2022
across 2 sources since Nov 2022

Extended reach

96,724
potential audience

Total likes

2,488

Video views

96,032

Mentions per month

Nov 2022 – Nov 2025

Where it's discussed

  • YouTube4 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

The discussions feature comments like 'this research clarifies the role of DHT in hair loss' and 'potential for new therapies,' emphasizing the scientific importance and possible future applications. The tone varies from scientific to hopeful, with words like 'significant,' 'promising,' and 'must explore,' reflecting both engagement and interest in the topic's relevance and impact.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, with some expressing strong support for its findings and implications.

InterestHigh interest

Many posts show high curiosity about the mechanisms of hair loss and potential treatments, indicating a strong interest.

EngagementModerate engagement

Participants refer to specific details such as DHT’s role and AR activation, demonstrating meaningful engagement with the content.

ImpactModerate impact

Several posts highlight the study’s potential influence on developing new treatments for androgenetic alopecia, suggesting a moderate perceived impact.

Abstract in brief

  • The study explores how dihydrotestosterone (DHT) activates the androgen receptor (AR) in C57BL6 mice, leading to hair loss similar to androgenetic alopecia (AGA) or male pattern baldness.
  • DHT causes hair regression, miniaturization, and loss of hair density in mice, effects that can be partly reversed with an AR blocker called bicalutamide.
  • The research suggests that DHT promotes these changes by triggering AR activation and nuclear translocation, which delays hair regrowth through specific alterations in hair follicle biology.]

Top posts

Most liked on X and Bluesky
Orlando_uy
@Orlando_uy · X

Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia. https://t.co/L6yLz54zYA

Nov 13, 2022 · 1 like · 693 followers View post →

All mentions

Orlando_uy
@Orlando_uy · X

Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia. https://t.co/L6yLz54zYA

Nov 13, 2022 · 1 like · 693 followers View post →