J Neurovirol February 2021 PMID 33528824

Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients.

Joanna Hellmuth, T Allen Barnett, Breton M Asken, J Daniel Kelly, Leonel Torres, Melanie L Stephens, Bryan Greenhouse, Jeffrey N Martin, Felicia C Chow, Steven G Deeks, Meredith Greene, Bruce L Miller, Wesley Annan, Timothy J Henrich, Michael J Peluso

Mentions

44
Peak: 21 in Feb 2021
across 3 sources since Feb 2021

Extended reach

139,556
potential audience

Total likes

40

Video views

35

Mentions per month

Feb 2021 – Jun 2024

Where it's discussed

  • X / Twitter39 posts
  • News3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The posts collectively support the research, emphasizing that even non-hospitalized patients experience lasting neurocognitive symptoms, with examples like mentions of deficits in working memory and executive functions. The tone reflects a strong consensus on the importance of these findings, and the references to recent case studies and observational data highlight the community's engagement and recognition of the issue's seriousness.

AgreementStrong agreement

Most posts express strong support for the findings, emphasizing that these cognitive issues are real and significant, with many referencing multiple studies and case reports to back their points.

InterestHigh interest

Posts demonstrate high engagement with the topic, including sharing detailed summaries of the research, discussing implications for patients, and referencing recent studies, indicating keen interest.

EngagementHigh engagement

Many posters analyze the study's methodology and implications, share personal reflections, and highlight ongoing research, showing deep involvement and thoughtful engagement with the subject.

ImpactHigh impact

The discussions underscore that these findings could influence medical understanding, patient care, and long-term health strategies related to COVID-19, indicating high perceived impact.

Abstract in brief

  • This article highlights that even nonhospitalized COVID-19 patients with mild to moderate symptoms can experience long-lasting neurocognitive issues, such as problems with working memory and executive functions, despite normal results on standard cognitive tests.
  • A study of 100 COVID-19 patients found that 14 nonhospitalized individuals reported persistent cognitive symptoms lasting around 9-10 weeks, with none experiencing symptom resolution during follow-up.
  • The authors suggest that potential causes of these cognitive issues include direct effects of the virus, immune system activation, or immune dysregulation, which future research should investigate further.]

Top posts

Most liked on X and Bluesky
Finn Wish (UK Medic)
@finn_wish · X

@JujuliaGrace Thanks @JujuliaGrace Also, many of us who contracted Covid-19 in the line of duty (but didn't die) are struggling with ongoing symptoms: Neurocognitive problems Respiratory problems Cardiac problems I am unable to think in depth or at speed anymore https://t.co/GQadrZnbLe

Feb 9, 2021 · 11 likes · 9 shares · 77 followers View post →
Finn Wish (UK Medic)
@finn_wish · X

@Dr2NisreenAlwan Well said @Dr2NisreenAlwan This Case study and early Observational study published 5 days ago shows neurocognitive problems in young and middle-aged patients who were NOT hospitalised. #LongCovid https://t.co/GQadrZnbLe

Feb 7, 2021 · 6 likes · 3 shares · 77 followers View post →
UCSF Fein Memory and Aging Center
@UCSFmac · X

Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients. Two cases of non-hospitalized patients recovering from COVID-19 with persistent neurocognitive symptoms. https://t.co/Z4HJs1bdN7 @BAsken8 @geri4life @brucemillerucsf @JNeuroVirology https://t.co/vHAwWmIiAw

Apr 14, 2021 · 3 likes · 2 shares · 6,193 followers View post →
Julio Pereira
@julio_neurosp · X

Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients: As cases of coronavirus disease 2019 (COVID-19) mount worldwide, attention is needed on potential long-term neurologic impacts for the majority of patients who… https://t.co/R13tRluKhl

Apr 26, 2021 · 3 likes · 6 shares · 3,080 followers View post →
Finn Wish (UK Medic)
@finn_wish · X

@bcdelaney1 @Dr2NisreenAlwan 1/ Agreed I found this Clinical Paper interesting. Published 2 Feb 2021: 2 case studies and an Observational study (20 patients with average age of 41 years) who developed persistent neurocognitive problems after Covid infection (non-hospitalised) https://t.co/GQadrZnbLe

Apr 27, 2021 · 2 likes · 1 share · 77 followers View post →
Finn Wish (UK Medic)
@finn_wish · X

@elisaperego78 @MinisteroSalute @LongCovidItalia @MartaEsperti Excellent News @elisaperego78 Yet more emerging data (published only 5 days ago) on the Neurocognitive problems in middle-aged patients who have NOT been hospitalised with Covid-19. https://t.co/GQadrZnbLe

Feb 7, 2021 · 2 likes · 1 share · 77 followers View post →

All mentions

Dr. Shanice T
@ShaniceT331135 · X

@LordOfTheYeti1 https://t.co/Hht4E62ZFc

Feb 7, 2024 · 1 like · 340 followers View post →
Existential Bread
@exist_bread · X

@catalinmpit It's become the butt of jokes, but you're exactly describing 'brain fog' and other neurocognitive symptoms in Long Covid (or other chronic illnesses). https://t.co/YyvNjiSSmw

Jan 8, 2024 · 969 followers View post →
hyper_sphere
@upgrded_btthle · X

@Ashly00001 @FDcookin123 @ElvisShepherd @spoonfulneptune @elonmusk Actually, COVID may have actually destroyed the part of their brain that critical thinking would usually take place: https://t.co/9Jo45qF9xg https://t.co/IvN6B57oul https://t.co/T2EF2Y6Li9

Oct 29, 2022 · 11 followers View post →
ACPSEMdance
@ACPSEMdance · X

RT @UCSFmac: Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients. Two cases of non-hospitalized patients re…

Sep 24, 2022 · 2 shares · 2,960 followers View post →
AntiCapitalist
@CapitalismEvil · X

@MmeBlackBalloon @Yash25571056 @KillBrexitNow https://t.co/3K72hit8rE

Jun 15, 2022 · 1 like · 1 share · 353 followers View post →
Nabil H The Peacemaker ⚛️☮️
@inabster · X

RT @finn_wish: @LEAD_Coalition @LOYALFAN1 @RespectYourself @saferprint @YvesMulkers @the_scholar1 @inabster @GreenGymPenge @cescept @memory…

Aug 5, 2021 · 1 share · 38,397 followers View post →
Julio Pereira
@julio_neurosp · X

RT @julio_neurosp: Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients: As cases of coronavirus disease 201…

May 26, 2021 · 6 shares · 3,080 followers View post →
Sue M.
@purplesgem · X

RT @finn_wish: @bcdelaney1 @Dr2NisreenAlwan 1/ Agreed I found this Clinical Paper interesting. Published 2 Feb 2021: 2 case studies and…

May 3, 2021 · 1 share · 4,953 followers View post →
Finn Wish (UK Medic)
@finn_wish · X

@bcdelaney1 @Dr2NisreenAlwan 1/ Agreed I found this Clinical Paper interesting. Published 2 Feb 2021: 2 case studies and an Observational study (20 patients with average age of 41 years) who developed persistent neurocognitive problems after Covid infection (non-hospitalised) https://t.co/GQadrZnbLe

Apr 27, 2021 · 2 likes · 1 share · 77 followers View post →
Cérebro
@RelativeBrain · X

RT @julio_neurosp: Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients: As cases of coronavirus disease 201…

Apr 26, 2021 · 6 shares · 2,380 followers View post →
NeuroSP - Neurocirurgião SP
@neurosp_ · X

RT @julio_neurosp: Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients: As cases of coronavirus disease 201…

Apr 26, 2021 · 6 shares · 132 followers View post →
Radiocirurgia
@radiocirurgia · X

RT @julio_neurosp: Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients: As cases of coronavirus disease 201…

Apr 26, 2021 · 6 shares · 1,255 followers View post →
Julio Pereira - Neurocirurgião SP
@neurocirurgiabr · X

RT @julio_neurosp: Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients: As cases of coronavirus disease 201…

Apr 26, 2021 · 6 shares · 31,108 followers View post →
Neurocirurgia São Paulo
@neuro_oncologia · X

RT @julio_neurosp: Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients: As cases of coronavirus disease 201…

Apr 26, 2021 · 6 shares · 1,703 followers View post →
Julio Pereira
@julio_neurosp · X

Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients: As cases of coronavirus disease 2019 (COVID-19) mount worldwide, attention is needed on potential long-term neurologic impacts for the majority of patients who… https://t.co/R13tRluKhl

Apr 26, 2021 · 3 likes · 6 shares · 3,080 followers View post →
Atlantic Fellows
@atlanticfellows · X

RT @UCSFmac: Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients. Two cases of non-hospitalized patients re…

Apr 15, 2021 · 2 shares · 5,258 followers View post →
UCSF Fein Memory and Aging Center
@UCSFmac · X

Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients. Two cases of non-hospitalized patients recovering from COVID-19 with persistent neurocognitive symptoms. https://t.co/Z4HJs1bdN7 @BAsken8 @geri4life @brucemillerucsf @JNeuroVirology https://t.co/vHAwWmIiAw

Apr 14, 2021 · 3 likes · 2 shares · 6,193 followers View post →
Jess Clay, PhD
@statistchick · X

@haekon1 @MiloB88586715 @ZubyMusic OK last one: https://t.co/qV8IlEzq3G I know, I went a little overboard :) You ask for studies and ye shall receive. Some of the studies are lower in generalizability than others IMO, but all are data-driven and not based on the same database.

Mar 8, 2021 · 713 followers View post →
UCSF Fein Memory and Aging Center
@UCSFmac · X

Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients. Detailed testing revealed working memory and executive functioning deficits. https://t.co/madMFqau46 https://t.co/SA1mc0BQ5F

Feb 24, 2021 · 1 like · 6,193 followers View post →
Stefan
@bendevon2 · X

RT @finn_wish: @JujuliaGrace Thanks @JujuliaGrace Also, many of us who contracted Covid-19 in the line of duty (but didn't die) are strug…

Feb 17, 2021 · 9 shares · 841 followers View post →
Finn Wish (UK Medic)
@finn_wish · X

@LEAD_Coalition @LOYALFAN1 @RespectYourself @saferprint @YvesMulkers @the_scholar1 @inabster @GreenGymPenge @cescept @memorytriggers @jagne_r @ogretmen_nesli @judehaste_write This Clinical Paper is very interesting: "We identified measurable executive functioning deficits in young and middle-aged adults who were never hospitalized with Covid. Study data suggests cognitive symptoms may last months or longer". https://t.co/GQadrZnbLe

Feb 16, 2021 · 2 likes · 1 share · 77 followers View post →
Dr Rave ✨
@Dr_Rave · X

RT @finn_wish: @Dr2NisreenAlwan Well said @Dr2NisreenAlwan This Case study and early Observational study published 5 days ago shows neuro…

Feb 10, 2021 · 3 shares · 2,487 followers View post →
UCSF RDO
@UCSF_RDO · X

COVID-19-associated neurocognitive symptoms in young and middle aged adults who were not hospitalized https://t.co/grfCwdvzqK

Feb 9, 2021 · 630 followers View post →
East View Cottage
@view_cottage · X

RT @finn_wish: @JujuliaGrace Thanks @JujuliaGrace Also, many of us who contracted Covid-19 in the line of duty (but didn't die) are strug…

Feb 9, 2021 · 9 shares · 1,290 followers View post →
Abdelaziz Amllay, MD
@AbdelazizAmllay · X

RT @UCSFmac: Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients. Cognitive changes appear to be common in…

Feb 9, 2021 · 2 shares · 241 followers View post →
Martin Dillon
@MartinD35757404 · X

RT @finn_wish: @JujuliaGrace Thanks @JujuliaGrace Also, many of us who contracted Covid-19 in the line of duty (but didn't die) are strug…

Feb 9, 2021 · 9 shares · 1,964 followers View post →
Sonja Marga
@MargaSonja · X

RT @finn_wish: @JujuliaGrace Thanks @JujuliaGrace Also, many of us who contracted Covid-19 in the line of duty (but didn't die) are strug…

Feb 9, 2021 · 9 shares · 1,078 followers View post →
BC
@Bernade63062744 · X

RT @finn_wish: @JujuliaGrace Thanks @JujuliaGrace Also, many of us who contracted Covid-19 in the line of duty (but didn't die) are strug…

Feb 9, 2021 · 9 shares · 2,310 followers View post →
confidence for life
@confidence4life · X

RT @finn_wish: @JujuliaGrace Thanks @JujuliaGrace Also, many of us who contracted Covid-19 in the line of duty (but didn't die) are strug…

Feb 9, 2021 · 9 shares · 1,037 followers View post →
Alison
@Alison34586950 · X

RT @finn_wish: @JujuliaGrace Thanks @JujuliaGrace Also, many of us who contracted Covid-19 in the line of duty (but didn't die) are strug…

Feb 9, 2021 · 9 shares · 3,358 followers View post →
htdht
@Austchloe · X

RT @finn_wish: @JujuliaGrace Thanks @JujuliaGrace Also, many of us who contracted Covid-19 in the line of duty (but didn't die) are strug…

Feb 9, 2021 · 9 shares · 2,054 followers View post →
Finn Wish (UK Medic)
@finn_wish · X

@JujuliaGrace Thanks @JujuliaGrace Also, many of us who contracted Covid-19 in the line of duty (but didn't die) are struggling with ongoing symptoms: Neurocognitive problems Respiratory problems Cardiac problems I am unable to think in depth or at speed anymore https://t.co/GQadrZnbLe

Feb 9, 2021 · 11 likes · 9 shares · 77 followers View post →
Finn Wish (UK Medic)
@finn_wish · X

@ClareGerada People's odd behaviour may be explained by infection with Covid-19. Has been shown to cause Executive Dysfunction: Behavioural control Attention control defects Difficulties in planning, abstracting, orientation and cognition And published last week https://t.co/GQadrZnbLe

Feb 8, 2021 · 77 followers View post →
Ancient Bat
@AncientBat · X

RT @finn_wish: @Dr2NisreenAlwan Well said @Dr2NisreenAlwan This Case study and early Observational study published 5 days ago shows neuro…

Feb 7, 2021 · 3 shares · 1,374 followers View post →
Long Covid Italia
@LongCovidItalia · X

RT @finn_wish: @elisaperego78 @MinisteroSalute @LongCovidItalia @MartaEsperti Excellent News @elisaperego78 Yet more emerging data (publi…

Feb 7, 2021 · 1 share · 3,667 followers View post →
Finn Wish (UK Medic)
@finn_wish · X

@elisaperego78 @MinisteroSalute @LongCovidItalia @MartaEsperti Excellent News @elisaperego78 Yet more emerging data (published only 5 days ago) on the Neurocognitive problems in middle-aged patients who have NOT been hospitalised with Covid-19. https://t.co/GQadrZnbLe

Feb 7, 2021 · 2 likes · 1 share · 77 followers View post →
Maria
@CatcatMariaa · X

RT @finn_wish: @Dr2NisreenAlwan Well said @Dr2NisreenAlwan This Case study and early Observational study published 5 days ago shows neuro…

Feb 7, 2021 · 3 shares · 1,124 followers View post →
Finn Wish (UK Medic)
@finn_wish · X

@Dr2NisreenAlwan Well said @Dr2NisreenAlwan This Case study and early Observational study published 5 days ago shows neurocognitive problems in young and middle-aged patients who were NOT hospitalised. #LongCovid https://t.co/GQadrZnbLe

Feb 7, 2021 · 6 likes · 3 shares · 77 followers View post →
UCSF Fein Memory and Aging Center
@UCSFmac · X

Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients. Cognitive changes appear to be common in young, otherwise healthy adults. Common cognitive screening tests may not detect these deficits. https://t.co/madMFqau46 @BAsken8 @brucemillerucsf https://t.co/TzlKjUOj78

Feb 4, 2021 · 1 like · 2 shares · 6,193 followers View post →
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