Nat Commun February 2021 PMID 33531498

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer.

Yuyan Jiang, Jiaguo Huang, Cheng Xu, Kanyi Pu

Mentions

7
Peak: 6 in Feb 2021
across 2 sources since Feb 2021

Extended reach

254,115
potential audience

Total likes

8

Video views

9

Mentions per month

Feb 2021 – Jun 2023

Where it's discussed

  • X / Twitter6 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions highlight excitement about the novel use of NIR-II light for precise cancer treatment, with phrases like 'photothermal immunotherapy' and 'nanoagonist' indicating interest in the technology's potential. The tone reflects both appreciation for the scientific advancement and anticipation of clinical impact, emphasizing the importance of the work for cancer research and nanomedicine.

AgreementModerate agreement

Most posts express support or approval of the publication's innovative approach and findings.

InterestHigh interest

Posts demonstrate high curiosity, emphasizing the novelty and potential of NIR-II activated nanoagents.

EngagementModerate engagement

Discussions include technical details such as references to photothermal effects and immune activation, indicating thoughtful engagement.

ImpactModerate impact

Posts suggest that this research could significantly influence future cancer therapies and nanomedicine development.

Abstract in brief

  • The study introduces a new polymer nanoagonist called APNA, which is activated by second near-infrared (NIR-II) light to enable precise, controllable cancer immunotherapy through combined photothermal effects and immune activation.
  • APNA is designed with a thermoresponsive linker that, when exposed to NIR-II irradiation, causes tumor ablation and releases an immunostimulant directly within deep tissue tumors, effectively stimulating local and systemic immune responses.
  • This method enhances immune cell infiltration in both the primary tumor and distant metastases, like the lung and liver, demonstrating a promising strategy for targeted, spatiotemporal cancer treatment with minimized side effects.]

Top posts

Most liked on X and Bluesky
Nature Communications
@NatureComms · X

Photothermally activatable semiconducting polymeric pro-agonist in second near-infrared window for photothermal immunotherapy. 10.1038/s41467-021-21047-0 #cancerresearch https://t.co/4zRawjN2tn

Feb 3, 2021 · 8 likes · 2 shares · 248,653 followers View post →
Dr. Rajesh Kumar Meena
@rajeshmeena38 · X

RT @NatureComms: Photothermally activatable semiconducting polymeric pro-agonist in second near-infrared window for photothermal immunother…

Feb 3, 2021 · 2 shares · 2,585 followers View post →
The Royal Vox Post
@RoyalVoxPost · X

#Nanomedicine: researchers synthesized polymer nanoagonists that can be activated by second near-infrared photothermia to trigger the liberation of immunostimulants. The nanoagents could help design new photothermal immunotherapies for #cancer treatment - https://t.co/uEUVSUKevU https://t.co/rKzSAX4hB5

Feb 2, 2021 · 2,080 followers View post →
Yatno Karno
@yatnokarno · X

RT @NatureComms: Photothermally activatable semiconducting polymeric pro-agonist in second near-infrared window for photothermal immunother…

Feb 3, 2021 · 2 shares · 397 followers View post →
Metha Biofund
@MBiofund · X

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer https://t.co/0unREdhjGQ

Feb 2, 2021 · 307 followers View post →
minnlab_litbot
@MLitbot · X

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer. https://t.co/VR202WgVTw https://t.co/PvOSjJkFLa

Feb 4, 2021 · 72 followers View post →

All mentions

minnlab_litbot
@MLitbot · X

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer. https://t.co/VR202WgVTw https://t.co/PvOSjJkFLa

Feb 4, 2021 · 72 followers View post →
Dr. Rajesh Kumar Meena
@rajeshmeena38 · X

RT @NatureComms: Photothermally activatable semiconducting polymeric pro-agonist in second near-infrared window for photothermal immunother…

Feb 3, 2021 · 2 shares · 2,585 followers View post →
Yatno Karno
@yatnokarno · X

RT @NatureComms: Photothermally activatable semiconducting polymeric pro-agonist in second near-infrared window for photothermal immunother…

Feb 3, 2021 · 2 shares · 397 followers View post →
Nature Communications
@NatureComms · X

Photothermally activatable semiconducting polymeric pro-agonist in second near-infrared window for photothermal immunotherapy. 10.1038/s41467-021-21047-0 #cancerresearch https://t.co/4zRawjN2tn

Feb 3, 2021 · 8 likes · 2 shares · 248,653 followers View post →
The Royal Vox Post
@RoyalVoxPost · X

#Nanomedicine: researchers synthesized polymer nanoagonists that can be activated by second near-infrared photothermia to trigger the liberation of immunostimulants. The nanoagents could help design new photothermal immunotherapies for #cancer treatment - https://t.co/uEUVSUKevU https://t.co/rKzSAX4hB5

Feb 2, 2021 · 2,080 followers View post →
Metha Biofund
@MBiofund · X

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer https://t.co/0unREdhjGQ

Feb 2, 2021 · 307 followers View post →