BMC Musculoskelet Disord February 2021 PMID 33536010

The comparison effects of intra-articular injection of Platelet Rich Plasma (PRP), Plasma Rich in Growth Factor (PRGF), Hyaluronic Acid (HA), and ozone in knee osteoarthritis; a one year randomized clinical trial.

Seyed Ahmad Raeissadat, Parsa Ghazi Hosseini, Mohammad Hasan Bahrami, Reza Salman Roghani, Mohammad Fathi, Azadeh Gharooee Ahangar, Mahtab Darvish

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Peak: 3 in Dec 2022

across 3 sources since Feb 2021

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Feb 2021 – Jun 2024

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The discussions mainly consist of references to the study, such as mentioning the one-year follow-up or the comparison of treatment effects, with some posts reflecting minimal commentary, which indicates a neutral stance and surface-level engagement. Word choice and tone suggest curiosity rather than enthusiasm or skepticism, emphasizing the technical aspects of the publication without extensive critical analysis.

AgreementNeither agree nor disagree

The discussions show neutrality, with some skepticism or lack of strong affirmations about the study results.

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There is mild interest indicated by the mention of follow-up and detailed study, but limited enthusiasm or critical engagement.

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Comments appear to be straightforward references or brief mentions without deep analysis or personal insights.

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The overall influence of these posts seems moderate; they bring attention but do not appear to provoke significant debate or widespread change in opinion.

Abstract in brief

The study compared the short- and long-term effectiveness of intra-articular injections of Hyaluronic Acid (HA), Platelet-Rich Plasma (PRP), Plasma Rich in Growth Factors (PRGF), and ozone in patients with knee osteoarthritis over one year.
All treatment groups showed significant pain and function improvement within 2 months, with ozone achieving the best short-term results, but its effects diminished by 6 months, whereas PRP and PRGF maintained better outcomes at 12 months.
Despite ozone's rapid initial improvement, PRP and PRGF proved to be more effective for sustained symptom relief over the year, with only these groups showing continued benefits at the 12-month follow-up.]

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Dr Murphy WeightLoss

@TakeWeightOffMD · X

@jointdocShields @generalorthomd https://t.co/srK3FYyx2J wrong

Jun 22, 2024 · 6,786 followers View post →

Dr Murphy WeightLoss

@TakeWeightOffMD · X

@generalorthomd https://t.co/srK3FYyx2J One year follow up trial.

Jun 22, 2024 · 6,786 followers View post →

⭐miGUE Iam⭐

@miGUE_Iam · X

RT @Rheumatology: The comparison effects of intra-articular injection of Platelet Rich Plasma (PRP), Plasma Rich in Growth Factor (PRGF), H…

Feb 16, 2021 · 1 share · 166 followers View post →

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@Rheumatology · X

Feb 15, 2021 · 10 likes · 1 share · 14,293 followers View post →

The comparison effects of intra-articular injection of Platelet Rich Plasma (PRP), Plasma Rich in Growth Factor (PRGF), Hyaluronic Acid (HA), and ozone in knee osteoarthritis; a one year randomized clinical trial.

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