Discussions reflect support and fascination with the research, with posts emphasizing how the findings challenge dieting myths, such as condemning calorie restriction as futile, and referencing complex biological signals involved in weight regain, which suggests a moderate but meaningful recognition of the research's significance.
AgreementModerate agreement
Most discussions recognize the importance of the research, especially in explaining the body's natural tendency to regain weight after dieting.
InterestHigh interest
Comments show high curiosity about the biological mechanisms and implications, with many urging others to learn more or highlighting new insights.
EngagementModerate engagement
Several posts engage deeply by referencing specific concepts like 'famine reaction,' feedback loops, and potential signals involved in weight regain.
ImpactModerate impact
The discussion indicates that the article could influence opinions about dieting practices and understanding weight regulation, although some remarks are more general.
Abstract in brief
The Minnesota Starvation Experiment, conducted in 1950, provides key insights into how the human body responds to long-term food deprivation, impacting physiology and behavior, and informing issues like eating disorders and obesity.
Recent analyses of the experiment's data reveal complex internal control systems that regulate body composition through feedback loops involving fat and lean mass, sensitive to initial fat levels, and linked to appetite and energy expenditure.
Understanding these autoregulatory mechanisms helps explain the body's natural tendency for weight regain after dieting, highlighting why weight cycling and obesity relapse are driven by fundamental physiological responses.
https://t.co/iQCcsIe0dT this is a really interesting revisiting of the Minnesota Starvation Experiment that is so dense i don't think i can pull a quote or summarize. give it a skim. it supports the "dieting changes your metabolism and brain-gut signaling in weird ways" principle
May 13, 2024 · 16 likes · 2 shares · 6,054 followersView post →
JL
Jens Lund
@jens_lund · X
The unknown biological signals and sensors of starvation and body weight regain:
“… feedback loops between the state of depletion of fat mass, as well as FFM, and the hunger–appetite centers play a central role in poststarvation hyperphagia”.
https://t.co/9KICNLsGnh
Feb 6, 2021 · 10 likes · 3 shares · 2,098 followersView post →
I
IberianCitizen
@IberianCitizen · X
Fisiología de la recuperación de peso: lecciones del clásico experimento de inanición de Minnesota sobre la regulación de la composición del cuerpo humano
sci-hub: статья не найдена / article not found☹️
https://t.co/hRT52WXnyt https://t.co/7TzFxwD8SK
Feb 5, 2021 · 4 likes · 12,901 followersView post →
JF
JORGE FERNANDEZ
@drjorfer · X
Physiology of weight regain: Lessons from the classic Minnesota Starvation Experiment on human body composition regulation - Dulloo - 2021 - Obesity Reviews - Wiley Online Library
Mar 17, 2025 · 1 like · 1,016 followersView post →
AG
Andy Grannell
@Grannell_ · X
@StephenORahilly Amazing work. Potentially some muscle derived signals interacting directly or indirectly with MC3R in the context of weight regain?
https://t.co/eOUl1vUUFn
https://t.co/XiEgWbclD0
The Minnesota Starvation Experiment reveals how the body responds to food deprivation, influencing physiology and behavior. Insights into internal control systems explain weight regain after dieting, highlighting the…
This video explores whether reverse dieting can boost metabolism, grounded in scientific insights from the Minnesota Starvation Experiment, which reveals the body's complex control systems regulating body composition…
Physiology of weight regain: Lessons from the classic Minnesota Starvation Experiment on human body composition regulation - Dulloo - 2021 - Obesity Reviews - Wiley Online Library
Mar 17, 2025 · 1 like · 1,016 followersView post →
I
INNOVADIETA
@INNOVADIETA · X
Physiology of weight regain: Lessons from the classic Minnesota Starvation Experiment on human body composition regulation - Dulloo - 2021 - Obesity Reviews - Wiley Online Library https://t.co/WdYKydbz3B https://t.co/MTio2rXpVP
RT @punished3liza: https://t.co/iQCcsIe0dT this is a really interesting revisiting of the Minnesota Starvation Experiment that is so dense…
May 13, 2024 · 2 shares · 293 followersView post →
OQ
Of Quartz
@PunishedQuartz · X
RT @punished3liza: https://t.co/iQCcsIe0dT this is a really interesting revisiting of the Minnesota Starvation Experiment that is so dense…
May 13, 2024 · 2 shares · 561 followersView post →
KT
komm, süssy tod
@punished3liza · X
https://t.co/iQCcsIe0dT this is a really interesting revisiting of the Minnesota Starvation Experiment that is so dense i don't think i can pull a quote or summarize. give it a skim. it supports the "dieting changes your metabolism and brain-gut signaling in weird ways" principle
May 13, 2024 · 16 likes · 2 shares · 6,054 followersView post →
FR
Fuel for Remewal
@fuelforrenewal · X
If you want to learn more about this experiment: https://t.co/Mupn8ZxIgs
@StephenORahilly Amazing work. Potentially some muscle derived signals interacting directly or indirectly with MC3R in the context of weight regain?
https://t.co/eOUl1vUUFn
https://t.co/XiEgWbclD0
The unknown biological signals and sensors of starvation and body weight regain:
“… feedback loops between the state of depletion of fat mass, as well as FFM, and the hunger–appetite centers play a central role in poststarvation hyperphagia”.
https://t.co/9KICNLsGnh
Feb 6, 2021 · 10 likes · 3 shares · 2,098 followersView post →
I
IberianCitizen
@IberianCitizen · X
Fisiología de la recuperación de peso: lecciones del clásico experimento de inanición de Minnesota sobre la regulación de la composición del cuerpo humano
sci-hub: статья не найдена / article not found☹️
https://t.co/hRT52WXnyt https://t.co/7TzFxwD8SK
Feb 5, 2021 · 4 likes · 12,901 followersView post →
I
Άννα Κολοκοτρώνη | Διαιτολόγος - Διατροφολόγος | Ο σωστός ...