PubHawk
January 2021 PMID 33552142

Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives.

Alexander Vaiserman, Dmytro Krasnienkov

Download social card

Mentions

106
Peak: 10 in Dec 2023
across 6 sources since Jan 2021

Extended reach

475,154
potential audience

Total likes

7,286

Video views

227,951

Mentions per month

Jan 2021 – Oct 2025

Where it's discussed

  • News48 articles
  • X / Twitter30 posts
  • YouTube19 videos
  • Blogs5 articles
  • Facebook3 posts
  • Bluesky1 posts

AI synopsis

What people are saying

The overall tone privileges the biological role of telomeres in aging, with posts highlighting their potential as markers and discussing recent research debates. Examples like the mention of telomere shortening limiting cell division and the need for integrating multiple biomarkers reflect a nuanced understanding and active engagement, while references to studies and citations demonstrate that this is a topic of ongoing scientific importance.

AgreementModerate agreement

Most discussions acknowledge the connection between telomeres and aging, recognizing it as a significant but imperfect biomarker.

InterestHigh interest

The posts indicate high interest, with references to ongoing research, potential implications, and detailed descriptions of telomere biology.

EngagementModerate engagement

Posts demonstrate moderate engagement, with participants summarizing findings, citing sources, and mentioning therapeutic perspectives.

ImpactModerate impact

The discussions suggest the research has meaningful implications for understanding aging and developing interventions, though some skepticism remains.

Abstract in brief

  • Telomere length (TL) is linked to cellular aging and age-related diseases, making it a potential biomarker for biological age, but it provides only a rough estimate rather than a precise prediction.
  • While TL has limitations as a standalone marker, combining it with other indicators like immune function, epigenetic data, and frailty measures can improve assessments of biological age.
  • Ongoing research debates focus on the accuracy and clinical usefulness of leukocyte TL for estimating human biological age, emphasizing the need to consider multiple biomarkers for better aging predictions.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives

Aug 29, 2025 · 10 likes · 41,196 followers View post →
Avraham Z. Cooper, MD
@AvrahamCooperMD · X

7/ Shortening w/ each replication, telomeres act like a counting mechanism for cells, limiting their mitotic potential. Once telomeres reach a certain length, this triggers a cell to enter senescence. We age as this process occurs throughout our bodies. https://t.co/bv6F3pHyGL https://t.co/A8Mw9rzHUX

Jul 4, 2024 · 8 likes · 115,971 followers View post →
Fat Jacques
@Fat_Jacques · X

@TheSimonEvans Yup. DNA ages. The ends of the strands are called telemores and over many replications these wear out, enabling the age of the DNA to be estimated. https://t.co/IwZSihKnX7

Nov 16, 2024 · 4 likes · 3,484 followers View post →
Agingdoc
@agingdoc1 · X

Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives ...recent research findings and divergent viewpoints regarding the usefulness of leukocyte TL for estimating the human biological age... https://t.co/kllvt9y0hO

Feb 14, 2021 · 2 likes · 1 share · 41,196 followers View post →
乾雅人｜社会課題と戦う医師
@Dr_inuimasato · X

https://t.co/BOfen2qib3

Mar 1, 2025 · 1 like · 4,448 followers View post →
Tony Milton
@deluxe_pastor · X

@ReformerOluseun https://t.co/ezJmjJTyny https://t.co/Km3Fn8olGe https://t.co/PFKF4lOfVM

May 3, 2024 · 1 like · 2,773 followers View post →

All mentions

Genomic Instability and Its Role in Aging Processes

This video explores the role of genomic instability in aging, highlighting cellular reprogramming and epigenetic rejuvenation as potential strategies to slow or reverse aging processes without losing cell identity.

Tuldun · Dec 11, 2023 1,538 views

Understanding the Role of Proteostasis Loss in Aging

This video explores how the loss of proteostasis influences aging, highlighting current research, limitations of telomere length as a biomarker, and the importance of combining multiple indicators for accurate…

Tuldun · Dec 15, 2023 809 views

Deregulated Nutrient Sensing and Its Role in Aging

This video explores how deregulated nutrient sensing impacts aging, emphasizing telomere length and other biomarkers to improve biological age assessments. It discusses current research and future perspectives on aging…

Tuldun · Dec 20, 2023 698 views

Cellular Senescence and the Future of Aging Research

This video explores cellular senescence and examines telomere length as a marker of biological age, highlighting limitations and the importance of combining multiple indicators for more accurate aging assessments.

Tuldun · Dec 22, 2023 390 views
Rob C
@Rob66733000 · X

@BrandonLuuMD 4yrs reduced telemere attrition by 140 bp. The normal attrition rate is 30-35 bp/yr. You can live another 4-5 years longer from four years of vit D use ? Not sure how much you gain. Other studies subjest a 25% lower death rate, prob 4-5yrs max best case https://t.co/xKVJctzCpn

Oct 29, 2025 · 1,068 followers View post →
Agingdoc
@agingdoc1 · X

Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives

Aug 29, 2025 · 10 likes · 41,196 followers View post →
luis hernan graffe
@hernangraffe · X

RT @hernangraffe: https://t.co/CFAzg3JBXk

Jul 4, 2025 · 3 shares · 3,132 followers View post →
luis hernan graffe
@hernangraffe · X

RT @hernangraffe: https://t.co/CFAzg3JBXk

Mar 6, 2025 · 3 shares · 3,132 followers View post →
乾雅人｜社会課題と戦う医師
@Dr_inuimasato · X

https://t.co/BOfen2qib3

Mar 1, 2025 · 1 like · 4,448 followers View post →
luis hernan graffe
@hernangraffe · X

RT @hernangraffe: https://t.co/CFAzg3JBXk

Jan 1, 2025 · 3 shares · 3,132 followers View post →
luis hernan graffe
@hernangraffe · X

https://t.co/CFAzg3JBXk

Dec 28, 2024 · 3 shares · 3,132 followers View post →
Fat Jacques
@Fat_Jacques · X

@TheSimonEvans Yup. DNA ages. The ends of the strands are called telemores and over many replications these wear out, enabling the age of the DNA to be estimated. https://t.co/IwZSihKnX7

Nov 16, 2024 · 4 likes · 3,484 followers View post →
Avraham Cooper
@avrahamcoopermd.bsky.social · Bluesky

7/ Shortening w/ each replication, telomeres act like a counting mechanism for cells, limiting their mitotic potential. Once telomeres reach a certain length, this triggers a cell to enter senescence. We age as this process occurs throughout our bodies. pubmed.ncbi.nlm.nih.gov/33552142/

Nov 11, 2024 · 1 share View post →
Damned Atheist
@AtheistDamned · X

@ketogrillbakery @S_Catsgotmyback https://t.co/pcwmBWmqew

Aug 1, 2024 · 1 like · 212 followers View post →
Bubbles
@CuricFran · X

@elonmusk https://t.co/qssd7EboDI https://t.co/5Pv7vCD53F

Jul 11, 2024 · 1,862 followers View post →
Avraham Z. Cooper, MD
@AvrahamCooperMD · X

7/ Shortening w/ each replication, telomeres act like a counting mechanism for cells, limiting their mitotic potential. Once telomeres reach a certain length, this triggers a cell to enter senescence. We age as this process occurs throughout our bodies. https://t.co/bv6F3pHyGL https://t.co/A8Mw9rzHUX

Jul 4, 2024 · 8 likes · 115,971 followers View post →
Tony Milton
@deluxe_pastor · X

@ReformerOluseun https://t.co/ezJmjJTyny https://t.co/Km3Fn8olGe https://t.co/PFKF4lOfVM

May 3, 2024 · 1 like · 2,773 followers View post →
Digidesperado | DUNE CREW
@digi_desperado · X

@RaoulGMI This frontiers article is a pretty solid read: https://t.co/fhvhwMsxcO For further articles, just read their citations. On the therapeutic front, it's more hypothesis testing and trials it seems.

Jan 22, 2024 · 1,681 followers View post →
GryphonWatcher
@GryphonWatcher · X

@marilynmaupin If you’re actually interested in this stuff, this paper is a decent overview of how aging works and the factors involved. From a anthropocentric perspective, but much of what is discussed applies to all mammals at a broad level: https://t.co/TkgctKHV3Q

Apr 11, 2023 · 245 followers View post →
Marianna Iatridou
@IatridouMar · X

https://t.co/lHRCMTrraw

Mar 12, 2023 · 600 followers View post →
Margaret Hudson
@Margare9355516 · X

https://t.co/tncS1jjPgI

Jan 13, 2023 · 4 followers View post →
Dr. Elden Wayne Whalen III, ShD
@wayne_effect · X

https://t.co/p612UUz3vK "Telomere shortening is a well-known hallmark of both cellular senescence and organismal aging."

Dec 18, 2022 · 1,267 followers View post →
Elena Todorova
@vega_x73 · X

Ну и эта ❤️ было бы хорошо узнать продолжение подобных иследований https://t.co/BFiOhnMfyV

Nov 21, 2022 · 995 followers View post →
branwen
@branwen41677029 · X

@PriyamvadaGopal Ageing changes happen but chromosomes remain the same, so chromosomes are pretty fundamental to life. In fact ageing changes in every cell in the body are controlled by chromosomes, and telomere length can act as a marker for age. https://t.co/HmZ8hBAnCZ

May 30, 2022 · 1,669 followers View post →
Julian Mutz
@julianmutz · X

RT @julianmutz: Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives Alexander Vaiserman…

Mar 15, 2022 · 1 share · 519 followers View post →
Julian Mutz
@julianmutz · X

Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives Alexander Vaiserman & Dmytro Krasnienkov https://t.co/Fh0XXDsSOK @FrontGenetics https://t.co/ad4wHLasc6

Mar 13, 2022 · 1 share · 519 followers View post →
attilacsordas
@attilacsordas · X

@kkariko thank you, although telomeres as biomarkers of aging or tissue aging clocks suffered some setbacks recently but they're still a contender and the mRNA platform of https://t.co/nzoF4FpMkG might be still a promising tool due to it's flexibility https://t.co/D3Eq8rGbof

Nov 1, 2021 · 4,307 followers View post →
`.´ nerdfunk
@nerdfunk · X

@Karl_Lauterbach Ein guter deep dive zum Thema Telomer-Länge die Korrelation mit Alterungsprozessen findet sich in folgendem Review: https://t.co/MGdNqb5LFg

Oct 17, 2021 · 1 like · 325 followers View post →
Diego Forero MD, PhD
@daforerog · X

Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives https://t.co/LS6kGqbLlM

Aug 5, 2021 · 1,597 followers View post →
Nansinguza Jacob
@NansinguzaJ · X

@digitaldidan 4) ....#telomere length (TL) has been recognized for a long time as one of the best biomarkers of aging. #Genetics #Ageing #Research https://t.co/j2FdvSPUD4

Jul 19, 2021 · 5,229 followers View post →
Dromograde
@Dromograde · X

RT @agingdoc1: Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives ...recent research fi…

Feb 14, 2021 · 1 share · 302 followers View post →
Agingdoc
@agingdoc1 · X

Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives ...recent research findings and divergent viewpoints regarding the usefulness of leukocyte TL for estimating the human biological age... https://t.co/kllvt9y0hO

Feb 14, 2021 · 2 likes · 1 share · 41,196 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives https://t.co/lUQg6VXk0M

Feb 9, 2021 · 2,240 followers View post →
New Medicine
@NewMedicine_ · X

#Telomere Length as a Marker of Biological #Age: State-of-the-Art, Open Issues, and Future Perspectives" by Alexander Vaiserman and Dmytro Krasnienkov https://t.co/t6TwNOdB9c https://t.co/dJOe6ZSzsz

Jan 26, 2021 · 78 followers View post →
Muzzpol
@Muzzpol · X

RT @mike_lustgarten: "Telomere length can only allow a rough estimate of aging rate and can hardly be regarded as a clinically important ri…

Jan 21, 2021 · 1 share · 860 followers View post →