Front Immunol June 2021 PMID 33584674

Sexual Dimorphism in Innate Immunity: The Role of Sex Hormones and Epigenetics.

Rebecca Shepherd, Ada S Cheung, Ken Pang, Richard Saffery, Boris Novakovic

Mentions

26
Peak: 3 in Feb 2021
across 3 sources since Feb 2021

Extended reach

8,363
potential audience

Total likes

11

Video views

95

Mentions per month

Feb 2021 – Apr 2025

Where it's discussed

  • News18 articles
  • X / Twitter6 posts
  • YouTube2 videos

AI synopsis

What people are saying

The overall discussions reflect recognition of the article's scientific focus, with comments like the review linking sex hormones and immune responses, indicating interest in the biological aspects. However, others, such as the dismissive remark about athletes and the derogatory tone, show engagement driven more by disagreement or controversy than by appreciation of the research's significance.

AgreementModerate agreement

Most discussions acknowledge the role of hormones and epigenetics in immune differences, showing general support for the publication's focus.

InterestModerate interest

The posts demonstrate some curiosity about the biological mechanisms, although the tone remains somewhat surface-level and lacks deep analysis.

EngagementNeutral engagement

While some comments briefly reference concepts like hormone influence and epigenetics, few posts delve into detailed implications or broader significance.

ImpactModerate impact

The discussions suggest that the article has a moderate impact by sparking awareness around sex-specific immune responses, though the tone remains somewhat dismissive or confrontational.

Abstract in brief

  • Sexual dimorphism in immune responses shows that females generally experience fewer infections but are more prone to autoimmune diseases, driven by differences in sex hormones and epigenetics.
  • Sex hormones like estrogen, progesterone, and testosterone directly influence immune cell behavior, and epigenetic factors such as DNA methylation also differ between sexes, affecting immune responses.
  • Changes in hormone levels during puberty, pregnancy, menopause, and hormone therapy cause shifts in gene expression and immune cell function, contributing to sex-specific immune characteristics.]

Top posts

Most liked on X and Bluesky
Michele Siosti
@MSiosti · X

@DavidPuente L'ignorante è lei! Si documenti su articoli scientifici prima di sparlare. https://t.co/wiXjoOsbeO Comunque la presenza di cromosoma xy implica alti livelli di testosterone e altre disfunzioni. Persone così non dovrebbero gareggiare con vere donne.

Aug 5, 2024 · 1 like · 36 followers View post →
Emily R Smith, ScD MPH
@DrEmilyRSmith · X

A review of sex-specific / pregnancy-associated hormones as drivers of epigenetic change that may contribute to the sexual dimorphism in innate immune function via @FrontImmunol https://t.co/lQ8bHydjFH

Aug 17, 2021 · 4,648 followers View post →
Transcriptomes
@transcriptomes · X

Sexual Dimorphism in Innate Immunity: The Role of Sex Hormones and Epigenetics. https://t.co/IxiiHVdi4I

Feb 16, 2021 · 1,811 followers View post →
SexGenomics
@sexgenomics · X

Sexual Dimorphism in Innate Immunity: The Role of Sex Hormones and Epigenetics. https://t.co/bZEe5MeK3K

Feb 17, 2021 · 1 share · 813 followers View post →
Princess Buttercup ☠
@sckitupbuttercp · X

@dimsie There is some sexual dimorphism in our immune system in response to pathogens due to hormones https://t.co/f7htjYzdX8.

Jun 19, 2022 · 664 followers View post →
Boris Novakovic
@nvk_brs · X

RT @sexgenomics: Sexual Dimorphism in Innate Immunity: The Role of Sex Hormones and Epigenetics. https://t.co/bZEe5MeK3K

Feb 17, 2021 · 1 share · 293 followers View post →

All mentions

Michele Siosti
@MSiosti · X

@DavidPuente L'ignorante è lei! Si documenti su articoli scientifici prima di sparlare. https://t.co/wiXjoOsbeO Comunque la presenza di cromosoma xy implica alti livelli di testosterone e altre disfunzioni. Persone così non dovrebbero gareggiare con vere donne.

Aug 5, 2024 · 1 like · 36 followers View post →
Princess Buttercup ☠
@sckitupbuttercp · X

@dimsie There is some sexual dimorphism in our immune system in response to pathogens due to hormones https://t.co/f7htjYzdX8.

Jun 19, 2022 · 664 followers View post →
Emily R Smith, ScD MPH
@DrEmilyRSmith · X

A review of sex-specific / pregnancy-associated hormones as drivers of epigenetic change that may contribute to the sexual dimorphism in innate immune function via @FrontImmunol https://t.co/lQ8bHydjFH

Aug 17, 2021 · 4,648 followers View post →
Boris Novakovic
@nvk_brs · X

RT @sexgenomics: Sexual Dimorphism in Innate Immunity: The Role of Sex Hormones and Epigenetics. https://t.co/bZEe5MeK3K

Feb 17, 2021 · 1 share · 293 followers View post →
SexGenomics
@sexgenomics · X

Sexual Dimorphism in Innate Immunity: The Role of Sex Hormones and Epigenetics. https://t.co/bZEe5MeK3K

Feb 17, 2021 · 1 share · 813 followers View post →
Transcriptomes
@transcriptomes · X

Sexual Dimorphism in Innate Immunity: The Role of Sex Hormones and Epigenetics. https://t.co/IxiiHVdi4I

Feb 16, 2021 · 1,811 followers View post →