February 2021 PMID 33589648

Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants.

Rui Wang, Jiahui Chen, Kaifu Gao, Yuta Hozumi, Changchuan Yin, Guo-Wei Wei

Mentions

58
Peak: 32 in Mar 2021
across 5 sources since Feb 2021

Extended reach

572,847
potential audience

Total likes

7,626

Video views

275,397

Mentions per month

Feb 2021 – Mar 2023

Where it's discussed

  • X / Twitter47 posts
  • Facebook4 posts
  • News3 articles
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

Overall, discussions highlight the significance of the research, with posts like @flyingsidekickr questioning the mutations' effects and @22ZaraHaz22 emphasizing normalcy and ongoing vaccination efforts, which shows varied tone from scientific curiosity to reassurance. Such comments, along with references to potential increased infectivity, demonstrate viewers' engagement and recognition of the article's relevance.

AgreementModerate agreement

Most discussions acknowledge the article's findings, especially regarding the identification of multiple substrains and their potential implications, indicating general support.

InterestHigh interest

Many posts express curiosity and concern about viral mutations, recombination, and their effects, reflecting high engagement with the topic.

EngagementModerate engagement

Some discussions delve into specific mutation details and the scientific significance, showing active participation, but a few posts dismiss the depth by sharing short comments.

ImpactModerate impact

Posts suggest that emerging variants and mutations could influence public health measures and virus transmissibility, indicating a moderate perceived impact.

Abstract in brief

  • The study analyzed 45494 SARS-CoV-2 genome sequences worldwide, including 12754 from the United States, and identified four distinct substrains and eleven top mutations, which are grouped into three disconnected clusters with two being more dominant.
  • The research found that mutations in the virus are evolving, with some becoming less common while others increase in prevalence, and one mutation (27964CTS24L on ORF8) shows a strong gender-related response, especially affecting females more actively than males.
  • Mutations in the spike protein suggest that two of the four U.S. SARS-CoV-2 substrains are becoming potentially more infectious, indicating ongoing changes that could impact the virus's transmissibility.

Top posts

Most liked on X and Bluesky
SciShow
@SciShow · X

Scientists may have found a recombinant variant of COVID-19 in the wild, and it's unclear whether this development is a threat, or an Achilles heel. https://t.co/mXF4v8jHeX https://t.co/ylhUrpzVmc

Mar 12, 2021 · 22 likes · 4 shares · 115,486 followers View post →
Raymond Schinazi
@drugbuster21 · X

Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants | Communications Biology https://t.co/meL4YGmfbR

Feb 19, 2021 · 5 likes · 908 followers View post →
Helena Ereditsh Dr
@ereditsh · X

COVID Variant Recombination: Threat or Achilles Heel? https://t.co/mInrEKyejH via @YouTube

Mar 14, 2021 · 4 likes · 1 share · 50,464 followers View post →
The Seeker
@TheSeeker268 · X

Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants: "We uncover that two of four SASR-CoV-2 substrains in the United States become potentially more infectious." https://t.co/7sHZN2mMdu

Feb 15, 2021 · 4 likes · 2 shares · 42,411 followers View post →
Gary Schroth
@Genomics_Guy · X

Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants https://t.co/KBd7JnILaQ

Feb 22, 2021 · 2 likes · 3,934 followers View post →
Patricia E Villasmil
@patricia2378 · X

Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants https://t.co/OYHZx7FVg4

Feb 15, 2021 · 1 like · 4,552 followers View post →

All mentions

Shawn Balk
@shawn_balk1 · X

RT @flyingsidekickr: What was going on here with 3 different mutations in a G-quartet or G-quadraplex-like sequence. Do #Mutations really r…

Mar 6, 2023 · 2 shares · 23 followers View post →
Hans Sars
@HansSars3 · X

RT @flyingsidekickr: What was going on here with 3 different mutations in a G-quartet or G-quadraplex-like sequence. Do #Mutations really r…

Feb 20, 2022 · 2 shares · 4 followers View post →
ShawnBalk
@flyingsidekickr · X

What was going on here with 3 different mutations in a G-quartet or G-quadraplex-like sequence. Do #Mutations really reflect pressures on protein function or a loss of utility of the RNA sequence compared to other pressures? #Evolution #SARSCoV2 #Pandemic https://t.co/zzVK8z4DIX https://t.co/KhkMBicHLC

Feb 15, 2022 · 2 shares · 1 followers View post →
Exen
@exentrik137 · X

@sailorsctaustin https://t.co/uWvxoE0qYl

Jul 25, 2021 · 142 followers View post →
Emily Williams
@gw_emily · X

@OSchonrock @ParisDaguerre This is a fairly good description overall. Diagram coming in next post. https://t.co/MO3cfFq70S

Jul 11, 2021 · 3,995 followers View post →
Peter Azak
@thepha · X

Just Liked on YouTube: COVID Variant Recombination: Threat or Achilles Heel? https://t.co/WhOrWQ8mo3

Jun 7, 2021 · 347 followers View post →
iscab.saptocondro
@saptocondro · X

Covid-19 variant recombination, https://t.co/FrePwkWY6n evolusi virus https://t.co/l468z25OAF

Mar 21, 2021 · 576 followers View post →
Cheryl Amber Dotson
@GODZILLASLAYS65 · X

Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants | Communications Biology https://t.co/P0g19GTOmP

Mar 21, 2021 · 1,095 followers View post →
Joogle83 #HouseAtreides #GladiatorEra
@JBTriple8 · X

@22ZaraHaz22 @WajahatAli there doing nothing we are on track to reopening on July 4th variants and recombination are normal and part of a virus life cycle stop fear-mongering the human race isnt going by a more severe common cold or its buddies Im getting my booster on the 30 https://t.co/PqnQhYvfWC

Mar 18, 2021 · 236 followers View post →
Ζeta KH
@Zzeta_d · X

@javitrmpt https://t.co/mXanJbMWJA

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ekokepe
@ekokepe · X

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Mar 15, 2021 · 360 followers View post →
Helena Ereditsh Dr
@ereditsh · X

COVID Variant Recombination: Threat or Achilles Heel? https://t.co/mInrEKyejH via @YouTube

Mar 14, 2021 · 4 likes · 1 share · 50,464 followers View post →
Brian W. Minor
@blueberrynuttz · X

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@JBTriple8 · X

@morningmoneyben ahem https://t.co/PqnQhYvfWC

Mar 14, 2021 · 236 followers View post →
Joogle83 #HouseAtreides #GladiatorEra
@JBTriple8 · X

the variants are just exposing weaknesses for the virus overall https://t.co/PqnQhYvfWC https://t.co/wiLS4XXF9I

Mar 14, 2021 · 236 followers View post →
ሣህለ ገብርኤል።
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RT @SciShow: Scientists may have found a recombinant variant of COVID-19 in the wild, and it's unclear whether this development is a threat…

Mar 14, 2021 · 4 shares · 1,211 followers View post →
PodcastsIListenTo
@PodcastsIListen · X

.@SciShow publishes daily videos about current questions from the world of science. https://t.co/0cJbaDecqR Newsletter: https://t.co/jsq9u5dDiI #biology #science #scishow #trivia #COVID #variant https://t.co/RjrzsyVoza

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グリュックスフェルド -
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@AndrsGarcaRamn1 · X

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@braco001 · X

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@SciShow · X

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@drugbuster21 · X

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@411_public · X

This chart illustrates an Analysis of SARS-CoV-2 Mutations in the United States Suggests Presence of Four Substrains and Novel Variants #COVID19 #VaccineEquity #PublicHealthatMeharry https://t.co/DgtxlA3lOp

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the paper link
@the_paper_link · X

Trend new: Wang R, ..., Wei GW (Commun Biol) __Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants__ https://t.co/8OyDfs2jFZ

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@nfanget · X

Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants #COVID19 https://t.co/DHTRAF7cDo

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@RetroVirox · X

Analysis of SARS-CoV-2 Mutations in the United States Suggests Presence of Four Substrains and Novel Variants | @scoopit https://t.co/2PKqxc7jSm #COVID19 #health #globalhealth #publichealth #medicine #biotechnology #pharmaceuticals #pandemic #infectiousdiseases #FDA #WHO #CDC

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Patricia E Villasmil
@patricia2378 · X

Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants https://t.co/OYHZx7FVg4

Feb 15, 2021 · 1 like · 4,552 followers View post →
Tavzb
@Vazeeam · X

#coronavirus #covid19 #maskup #wearamask #covididiots Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants https://t.co/JONeCjnvo9

Feb 15, 2021 · 3,986 followers View post →
Sangeeta Motiani
@sangmotiani · X

RT @TheSeeker268: Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants: "We uncove…

Feb 15, 2021 · 2 shares · 283 followers View post →
The Seeker
@TheSeeker268 · X

Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants: "We uncover that two of four SASR-CoV-2 substrains in the United States become potentially more infectious." https://t.co/7sHZN2mMdu

Feb 15, 2021 · 4 likes · 2 shares · 42,411 followers View post →