July 2021 PMID 33596212

Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer.

Claire Guest, Rob Harris, Karen S Sfanos, Eva Shrestha, Alan W Partin, Bruce Trock, Leslie Mangold, Rebecca Bader, Adam Kozak, Scott Mclean, Jonathan Simons, Howard Soule, Thomas Johnson, Wen-Yee Lee, Qin Gao

Mentions

61
Peak: 40 in Feb 2021
across 3 sources since Sep 2020

Extended reach

965,493
potential audience

Total likes

4,298

Video views

188,915

Mentions per month

Sep 2020 – Jun 2025

Where it's discussed

  • X / Twitter54 posts
  • News5 articles
  • YouTube2 videos

AI synopsis

What people are saying

The overall sentiment reflects enthusiasm and strong support, with posts highlighting the scientific promise of canine detection, such as mentions of accuracy and potential for non-invasive testing, and ideas for broader applications like AI integration and screening strategies, all conveyed through positive language and a tone of optimism about future breakthroughs.

AgreementStrong agreement

The majority of discussions are highly supportive, emphasizing the promising potential of using canine olfaction for prostate cancer detection, with comments referencing its accuracy and practical value.

InterestHigh interest

Participants demonstrate a high level of curiosity, discussing how dogs can detect cancer, the integration with AI, and potential applications in public health, indicating deep interest in the research and its implications.

EngagementHigh engagement

Many discussions delve into the science behind the detection methods, referencing specific studies, methodology, and future directions, showing substantial engagement and thoughtful commentary.

ImpactHigh impact

There is a strong consensus that this research could revolutionize prostate cancer detection, with comments about it being a 'game changer,' and potential to improve non-invasive diagnostics, indicating high perceived impact.

Abstract in brief

  • Prostate cancer is the second leading cause of cancer death among men in developed countries, highlighting the need for better detection methods beyond traditional PSA testing.
  • Using trained dogs to detect cancer through smell shows promise, but practical application relies on machine olfaction technologies.
  • A pilot study combining canine olfaction, volatile organic compound analysis, and microbial profiling found that dogs could detect advanced prostate cancer with 71% sensitivity and significant differences in VOCs and microbiota were confirmed between cancer-positive and control samples.

Top posts

Most liked on X and Bluesky
The Johns Hopkins Brady Urological Institute
@brady_urology · X

A dog’s nose may know the difference between high & low-grade #prostatecancer. @alan_partin @brucetrock @sfanoslab & team joined @MedDetectDogs @PCFnews @MIT to investigate canine olfaction of PC. Learn more about our work & future development in @PLOSONE https://t.co/ivdwSOP3KA

Feb 17, 2021 · 11 likes · 4 shares · 7,047 followers View post →
The Johns Hopkins Brady Urological Institute
@brady_urology · X

Integrating canine olfaction with chemical and microbial profiling of urine to detect lethal #prostatecancer @sfanoslab @alan_partin @brucetrock @djmcconkey @leslie_mangold https://t.co/FKUw9nPjOQ @PLOSONE @HopkinsMedicine https://t.co/1dHbwBDiXx

Feb 18, 2021 · 10 likes · 2 shares · 7,047 followers View post →
PLOS
@PLOS · X

A multinational team has reported an #AI-powered system that is as accurate as trained dogs at correctly identifying cases of #ProstateCancer from urine samples.

May 12, 2021 · 8 likes · 1 share · 147,405 followers View post →
Andreas Mershin
@AndreasMershin · X

#PLOSONE: Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detec ... https://t.co/uhmAlgCi1M

Feb 17, 2021 · 8 likes · 568 followers View post →
Dogs Trust's Canine Behaviour & Research Teams
@DTScholars · X

❓#FunFactFriday

Feb 19, 2021 · 7 likes · 4 shares · 3,963 followers View post →
Gircor, recherche animale et alternatives
@GIRCOR · X

Apprendre aux #chiens à détecter le #cancer de la #prostate pour améliorer les tests de diagnostic https://t.co/H1lBVvewdC https://t.co/SYDtCflO2a

Feb 20, 2021 · 5 likes · 1 share · 3,944 followers View post →

All mentions

Beat Meyer
@beatmeyer · X

Via https://t.co/Ct08T3QQ57 "... It's #WorldCancerDay, and Florin is one of our team of dogs that can detect the most aggressive forms of #prostatecancer from a urine sample, even in patients with other diseases of the prostate."…https://t.co/VdGVUHOy2W https://t.co/WpqId2IeD1

Feb 17, 2022 · 1 like · 1,009 followers View post →
Lee Woodworth
@leewoodworth · X

@CMOH_NL @EasternHealthNL Apparently they can train dogs to detect any disease, including COVID-19. We could screen a whole school with a couple dogs on the way in every morning. Malcolm Gladwell did a piece on this recently. Related study: https://t.co/ug7ULeWEeS

Aug 31, 2021 · 151 followers View post →
Zev Leopold, MD
@ZevLeopold · X

For more info see: Guest C, Harris R, Sfanos KS eat al. Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer. PLOS ONE 16(2): e0245530. https://t.co/lYoDaMGKRv

Aug 27, 2021 · 358 followers View post →
godfrey™
@godfrey_G_ · X

RT @PLOS: A multinational team has reported an #AI-powered system that is as accurate as trained dogs at correctly identifying cases of #Pr…

May 14, 2021 · 3 shares · 5,010 followers View post →
Dr. د. عبدالواحد الزهراني
@ralzahrani2020 · X

RT @PLOS: A multinational team has reported an #AI-powered system that is as accurate as trained dogs at correctly identifying cases of #Pr…

May 14, 2021 · 3 shares · 4,414 followers View post →
gettinganoldITUnurse
@JantyMilloy · X

RT @PLOS: A multinational team has reported an #AI-powered system that is as accurate as trained dogs at correctly identifying cases of #Pr…

May 14, 2021 · 3 shares · 256 followers View post →
PLOS
@PLOS · X

A multinational team has reported an #AI-powered system that is as accurate as trained dogs at correctly identifying cases of #ProstateCancer from urine samples.

May 14, 2021 · 4 likes · 3 shares · 147,405 followers View post →
mara andrione
@brnzupp · X

RT @PLOS: A multinational team has reported an #AI-powered system that is as accurate as trained dogs at correctly identifying cases of #Pr…

May 12, 2021 · 1 share · 213 followers View post →
PLOS
@PLOS · X

A multinational team has reported an #AI-powered system that is as accurate as trained dogs at correctly identifying cases of #ProstateCancer from urine samples.

May 12, 2021 · 8 likes · 1 share · 147,405 followers View post →
Sperling Medical Group
@SperlingMedical · X

Understanding how dogs can detect #prostatecancer based on urine odor may help identify molecular compounds so computers have similar diagnostic accuracy. https://t.co/Y7ajz5lXBB

Mar 12, 2021 · 335 followers View post →
bruce trock
@brucetrock · X

Brady part of team identifying how dogs sniff out prostate cancer: https://t.co/AiyAcZEtmT

Mar 10, 2021 · 101 followers View post →
上田悠理 Yuuri Ueda Dr.ゆーり/医師・ヘルステックプロモーター
@YuuriU · X

https://t.co/sC6hNKJMdp

Mar 1, 2021 · 3 likes · 2,731 followers View post →
La Science, CQFD
@ScienceCQFD · X

[L’étude à découvrir] 17/02 > Faisabilité d'intégrer l'olfaction canine au profilage chimique et microbien de l'urine pour détecter un cancer de la prostate mortel https://t.co/6JZ36U2HR6 via @PLOSONE #LaMethSci

Feb 26, 2021 · 1 like · 57,681 followers View post →
Fabio Grizzi
@FabioGrizzi · X

“In 2015, Taverna et al. published a pivotal paper on the canine detection of prostate cancer from urine...olfactory detection of prostate cancer holds the promise of rapid and non-invasive diagnosi” From https://t.co/lPoDUy2zHI Congratulations to our friends @MedDetectDogs

Feb 24, 2021 · 810 followers View post →
@investigando
@rocatanho · X

El sistema olfatorio canino sería 71 % sensible y 70-76 % específico detectando cáncer de próstata Gleason 9 en muestras de orina. https://t.co/RwRayDQskx

Feb 23, 2021 · 397 followers View post →
amaranta
@palanquetaa · X

también cosas como perritos detectores de cáncer de próstata como en este artículo https://t.co/bRcKw0sud9

Feb 23, 2021 · 1 like · 500 followers View post →
Katharine Anderson
@KL_Anderson7 · X

RT @DTScholars: ❓#FunFactFriday

Feb 22, 2021 · 4 shares · 833 followers View post →
Machine Learning Bot
@ML_Tweet_Bot · X

RT @JustinDomke: I think this paper is basically doing distillation of a model learned by a dog's brain into a machine learning model. (W…

Feb 21, 2021 · 1 share · 10,137 followers View post →
Justin Domke
@JustinDomke · X

I think this paper is basically doing distillation of a model learned by a dog's brain into a machine learning model. (What's the inductive bias that dogs use to generalize so well?) https://t.co/POvo4WwIMY https://t.co/ezoxlL0P5l

Feb 21, 2021 · 1 share · 328 followers View post →
SIMV
@SIMV_RP · X

RT @recherche_anima: Apprendre aux #chiens à détecter le #cancer de la #prostate pour améliorer les tests de diagnostic https://t.co/H1lBVv…

Feb 21, 2021 · 1 share · 1,914 followers View post →
David Menon
@Menon_Cambridge · X

Good dogs. Clever dogs. Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer https://t.co/B9COSnrObN

Feb 20, 2021 · 2,937 followers View post →
Gircor, recherche animale et alternatives
@GIRCOR · X

Apprendre aux #chiens à détecter le #cancer de la #prostate pour améliorer les tests de diagnostic https://t.co/H1lBVvewdC https://t.co/SYDtCflO2a

Feb 20, 2021 · 5 likes · 1 share · 3,944 followers View post →
Prostate Cell News
@ProstateCell · X

Can a dog's nose

Feb 20, 2021 · 1,970 followers View post →
The Urology Applicant ⚕
@Uro_Res · X

@ZavaskiMD @brady_urology @PLOSONE @biorxivpreprint Good call link here https://t.co/ULnSmkMuEb

Feb 19, 2021 · 1 like · 8,070 followers View post →
Sarah Ghosh
@SarahGhosh20 · X

This is interesting... dogs can detect prostate cancer with their keen sense of smell https://t.co/FlqwQzewaW

Feb 19, 2021 · 237 followers View post →
Garry South
@GarrySouth · X

RT @HolmesHaddad: Just when I think I can't possibly love dogs any more, they're learning to sniff out #ProstateCancer. Sigh. https://t.co…

Feb 19, 2021 · 1 share · 1,916 followers View post →
Laura Holmes Haddad
@HolmesHaddad · X

Just when I think I can't possibly love dogs any more, they're learning to sniff out #ProstateCancer. Sigh. https://t.co/QU1N6njH8W

Feb 19, 2021 · 1 like · 1 share · 467 followers View post →
ken crichlow
@ken_crichlow · X

RT @PLOS: Dogs trained to sniff out #ProstateCancer could help us develop better tests, say Claire Guest and Rob Harris of @MedDetectDogs a…

Feb 19, 2021 · 3,958 followers View post →
PLOS
@PLOS · X

Dogs trained to sniff out #ProstateCancer could help us develop better tests, say Claire Guest and Rob Harris of @MedDetectDogs and colleagues.

Feb 19, 2021 · 3 likes · 147,405 followers View post →
Ken Gusler
@kgusler · X

Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer: https://t.co/27Wrcctrja

Feb 19, 2021 · 20,018 followers View post →
Ade
@AdeMcCann · X

RT @DTScholars: ❓#FunFactFriday

Feb 19, 2021 · 4 shares · 1,050 followers View post →
Fabricio F. Costa
@ffalconi · X

Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer https://t.co/aqKkbGdbCO

Feb 19, 2021 · 1 like · 1,705 followers View post →
Microbiome Bot
@MicrobiomeBot · X

Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer. https://t.co/qY5DkQOaWm https://t.co/CbX0LC8ib3

Feb 19, 2021 · 419 followers View post →
MDSP
@MDSPNews · X

RT @DTScholars: ❓#FunFactFriday

Feb 19, 2021 · 4 shares · 162 followers View post →
The Dog Behaviourist Manchester UK
@dog_manchester · X

RT @DTScholars: ❓#FunFactFriday

Feb 19, 2021 · 4 shares · 12 followers View post →
Dogs Trust's Canine Behaviour & Research Teams
@DTScholars · X

❓#FunFactFriday

Feb 19, 2021 · 7 likes · 4 shares · 3,963 followers View post →
Dataemia
@Dataemia · X

(Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer.) https://t.co/pjXcC2FcEh

Feb 19, 2021 · 961 followers View post →
Luanne Szymanski
@LuanneMfunds · X

RT @brady_urology: Integrating canine olfaction with chemical and microbial profiling of urine to detect lethal #prostatecancer @sfanoslab…

Feb 18, 2021 · 2 shares · 147 followers View post →
Sky Health, LLC
@GotSkyHealth · X

Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer #canine #prostatecancer #cancer https://t.co/8yHoTuY9Vg

Feb 18, 2021 · 72 followers View post →
Immunity DX
@DxImmunity · X

Dogs are good for your immune system and emotional well being too. Theranostic pets

Feb 18, 2021 · 1 like · 197 followers View post →
Double Whammy
@double_whammied · X

Why yes, scientists are using dogs to train AI so it can "sniff out" #cancer better in screenings. #dogsrulecancerdrools #PLOSONE: Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detec ... https://t.co/hLfxLboXZp

Feb 18, 2021 · 8,669 followers View post →
Alan Partin
@alan_partin · X

RT @brady_urology: Integrating canine olfaction with chemical and microbial profiling of urine to detect lethal #prostatecancer @sfanoslab…

Feb 18, 2021 · 2 shares · 2,594 followers View post →
Paul Vincelli
@Pvincell · X

Dogs may have a role in detecting lethal prostate cancer by smell: https://t.co/TC3JqtX4bN

Feb 18, 2021 · 1,385 followers View post →
The Johns Hopkins Brady Urological Institute
@brady_urology · X

Integrating canine olfaction with chemical and microbial profiling of urine to detect lethal #prostatecancer @sfanoslab @alan_partin @brucetrock @djmcconkey @leslie_mangold https://t.co/FKUw9nPjOQ @PLOSONE @HopkinsMedicine https://t.co/1dHbwBDiXx

Feb 18, 2021 · 10 likes · 2 shares · 7,047 followers View post →
Paperbirds_Oncology
@PaperbirdsO · X

New article: Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer. https://t.co/17wbuQHTBv #prostatecancer #oncology https://t.co/snfMU6Mq7g

Feb 18, 2021 · 890 followers View post →
Microbiome Articles
@microbe_article · X

Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cance... - Guest C et al. - https://t.co/jxiaTqTZSv #microbiome

Feb 18, 2021 · 7,153 followers View post →
Oncology & Machine Learning
@MlOncology · X

Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer https://t.co/vjJVmidL7W

Feb 17, 2021 · 213 followers View post →
Alan Partin
@alan_partin · X

RT @brady_urology: A dog’s nose may know the difference between high & low-grade #prostatecancer. @alan_partin @brucetrock @sfanoslab & tea…

Feb 17, 2021 · 4 shares · 2,594 followers View post →
Hopkins Med News
@HopkinsMedNews · X

RT @brady_urology: A dog’s nose may know the difference between high & low-grade #prostatecancer. @alan_partin @brucetrock @sfanoslab & tea…

Feb 17, 2021 · 4 shares · 15,478 followers View post →
The Johns Hopkins Brady Urological Institute
@brady_urology · X

A dog’s nose may know the difference between high & low-grade #prostatecancer. @alan_partin @brucetrock @sfanoslab & team joined @MedDetectDogs @PCFnews @MIT to investigate canine olfaction of PC. Learn more about our work & future development in @PLOSONE https://t.co/ivdwSOP3KA

Feb 17, 2021 · 11 likes · 4 shares · 7,047 followers View post →
Andreas Mershin
@AndreasMershin · X

#PLOSONE: Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detec ... https://t.co/uhmAlgCi1M

Feb 17, 2021 · 8 likes · 568 followers View post →
Ordo Fraterna Fibonacci
@OrdoFibonacci · X

#PLOSONE: Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detec ... https://t.co/BvpDSdDE24

Feb 17, 2021 · 2,565 followers View post →
Microbiome Bot
@MicrobiomeBot · X

Feasibility of Integrating Canine Olfaction with Chemical and Microbial Profiling of Urine to Detect Lethal Prostate Cancer https://t.co/MGPDjZT8vM

Sep 11, 2020 · 419 followers View post →
bioRxiv
@biorxivpreprint · X

Feasibility of Integrating Canine Olfaction with Chemical and Microbial Profiling of Urine to Detect Lethal Prostate Cancer https://t.co/mOYcPM1BeQ #bioRxiv

Sep 10, 2020 · 138,193 followers View post →
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