Pharmacol Rep April 2021 PMID 33609274

Ketamine-50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms.

Samuel Kohtala

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Mentions

28
Peak: 8 in Feb 2021
across 5 sources since Feb 2021

Extended reach

199,973
potential audience

Total likes

738

Video views

30,017

Mentions per month

Feb 2021 – Apr 2025

Where it's discussed

  • X / Twitter19 posts
  • YouTube4 videos
  • Facebook2 posts
  • News2 articles
  • Bluesky1 posts

AI synopsis

What people are saying

Many discussions highlight ketamine's transformation from an obscure anesthetic to a prominent treatment for depression and pain, using words like 'innovative,' 'wonder drug,' and 'powerful' to convey its significance. The tone varies from informational to enthusiastic, reflecting both respect for its history and excitement about its evolving uses.

AgreementModerate agreement

Most discussions recognize and support the article's description of ketamine's evolving role from anesthesia to psychiatric treatment, as seen in phrases like 'powerful battlefield anesthetic' and 'wonder drug of modern psychiatry.'

InterestHigh interest

The discussions show a high level of curiosity, with many posts expressing interest in ketamine's diverse applications and its journey over decades.

EngagementModerate engagement

Posts often delve into topics like dissociation, neurobiological mechanisms, and clinical applications, indicating moderate engagement with detailed content.

ImpactModerate impact

The conversations suggest the article has a notable influence, informing ongoing debates and awareness about ketamine's therapeutic potential.

Abstract in brief

  • Ketamine has been a crucial anesthetic in both human and veterinary medicine for over 50 years, and recent studies are exploring its use for chronic pain, drug addiction, and PTSD.
  • * Its rapid antidepressant effects have sparked significant research interest, although the specific molecular mechanisms behind these effects are still not fully understood.
  • * The review highlights various applications of ketamine, the importance of dosage in antidepressant studies, and discusses new hypotheses about how ketamine works in the brain.

Top posts

Most liked on X and Bluesky
Samuel Kohtala
@samuelkohtala · X

For anyone interested in getting a brief overview of ketamine and its many uses along with some insights to its complex profile antidepressant effects, my review published today might be of use: " https://t.co/tVi84JQAYq #ketamine #antidepressant #neuropharmacology

Feb 20, 2021 · 17 likes · 5 shares · 572 followers View post →
dough
@semodough · X

@Pharmdca $PHRRF $SEEL https://t.co/Qx5i2VodSI

Jul 13, 2021 · 14 likes · 1 share · 41,537 followers View post →
George Dawson
@dawso007 · X

Open Access: "Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms" — Read it on @ResearchGate: https://t.co/oOLKPo8Msp

Feb 18, 2022 · 8 likes · 3 shares · 7,813 followers View post →
truthseeker1983.bsky.social
@truthseeker1983.bsky.social · Bluesky

Ketamin, an obscure 50 plus year old drug, untill recently, has been used as an anesthesia by the MDs and the veterinarians. Over the last decade it's being used as an anti-depressant, for managing chronic pain, etc., along with other therapies.

Apr 9, 2025 · 3 likes · 2 shares View post →
Jari Yli-Kauhaluoma
@JYK_Viikki · X

A new review by @samuelkohtala #Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms https://t.co/FxgMleyEKO #DrugResearchProgram #FTDK #viikkicampus @LifeSciHelsinki

Mar 15, 2021 · 2 likes · 1,306 followers View post →
Pharmdca
@Pharmdca · X

RT @semodough: @Pharmdca $PHRRF $SEEL https://t.co/Qx5i2VodSI

Jul 13, 2021 · 1 share · 108,992 followers View post →

All mentions

truthseeker1983.bsky.social
@truthseeker1983.bsky.social · Bluesky

Ketamin, an obscure 50 plus year old drug, untill recently, has been used as an anesthesia by the MDs and the veterinarians. Over the last decade it's being used as an anti-depressant, for managing chronic pain, etc., along with other therapies.

Apr 9, 2025 · 3 likes · 2 shares View post →
Christina Melaney (Stabrowska)
@Gardencare2013 · X

Dissociation, exactly... https://t.co/zA0zDnu7Hr

Feb 24, 2025 · 1,151 followers View post →
Physicians Ketamine Institute of Destin
@PkiofDestin · X

Learn more about this innovative treatment’s journey from anesthetic to antidepressant at https://t.co/whSOSU94pB. You may also check out this article: https://t.co/vX9iQBY698. #DestinFL #KetamineTherapy #Anesthetic #Antidepressant https://t.co/8kzgtqyejO

Feb 21, 2024 · 7 followers View post →
Taha Al Muhammadee Janjua
@tahajanjua · X

RT @dawso007: Open Access: "Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms" — Re…

Feb 18, 2022 · 3 shares · 236 followers View post →
John Peters
@johnthejack · X

RT @dawso007: Open Access: "Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms" — Re…

Feb 18, 2022 · 3 shares · 4,905 followers View post →
George Dawson
@dawso007 · X

Open Access: "Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms" — Read it on @ResearchGate: https://t.co/oOLKPo8Msp

Feb 18, 2022 · 8 likes · 3 shares · 7,813 followers View post →
Pharmdca
@Pharmdca · X

RT @semodough: @Pharmdca $PHRRF $SEEL https://t.co/Qx5i2VodSI

Jul 13, 2021 · 1 share · 108,992 followers View post →
dough
@semodough · X

@Pharmdca $PHRRF $SEEL https://t.co/Qx5i2VodSI

Jul 13, 2021 · 14 likes · 1 share · 41,537 followers View post →
Lone Star Infusion - Ketamine in Houston
@ketaminehouston · X

"from a powerful battlefield anesthetic to the wonder drug of modern psychiatry..." https://t.co/Cvf3J5X6ar

Apr 28, 2021 · 15 followers View post →
Samuel Kohtala
@samuelkohtala · X

An introduction to ketamine and dissociation https://t.co/vHkGSCUfgm

Mar 28, 2021 · 573 followers View post →
Jari Yli-Kauhaluoma
@JYK_Viikki · X

A new review by @samuelkohtala #Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms https://t.co/FxgMleyEKO #DrugResearchProgram #FTDK #viikkicampus @LifeSciHelsinki

Mar 15, 2021 · 2 likes · 1,306 followers View post →
Dr. Jodie Stevenson
@getjazzed8 · X

RT @Eumayrs: https://t.co/ksyDW6svSc

Mar 9, 2021 · 3 shares · 260 followers View post →
Sleepwell
@SleepwellPrgm · X

RT @samuelkohtala: For anyone interested in getting a brief overview of ketamine and its many uses along with some insights to its complex…

Feb 24, 2021 · 5 shares · 57 followers View post →
PsychiatryAI.com
@PsychiatryAIcom · X

Ketamine-50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms https://t.co/6eqTWuqr9s

Feb 23, 2021 · 435 followers View post →
Young Onset Parkinson’s Disease
@Dopamine_Hacker · X

RT @samuelkohtala: For anyone interested in getting a brief overview of ketamine and its many uses along with some insights to its complex…

Feb 23, 2021 · 5 shares · 36 followers View post →
PsychiatryAI.com
@PsychiatryAIcom · X

Ketamine-50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms. https://t.co/W9TOziIL0S

Feb 21, 2021 · 435 followers View post →
Sveta Molchanova
@Svetadotfi · X

RT @samuelkohtala: For anyone interested in getting a brief overview of ketamine and its many uses along with some insights to its complex…

Feb 21, 2021 · 5 shares · 206 followers View post →
Tomi Rantamäki
@TomiRantamki · X

RT @samuelkohtala: For anyone interested in getting a brief overview of ketamine and its many uses along with some insights to its complex…

Feb 20, 2021 · 5 shares · 212 followers View post →
Puja Parekh, Ph.D.
@_DrOctothorpe_ · X

RT @samuelkohtala: For anyone interested in getting a brief overview of ketamine and its many uses along with some insights to its complex…

Feb 20, 2021 · 5 shares · 1,117 followers View post →
Samuel Kohtala
@samuelkohtala · X

For anyone interested in getting a brief overview of ketamine and its many uses along with some insights to its complex profile antidepressant effects, my review published today might be of use: " https://t.co/tVi84JQAYq #ketamine #antidepressant #neuropharmacology

Feb 20, 2021 · 17 likes · 5 shares · 572 followers View post →