Geroscience August 2021 PMID 33650014

Circulating fatty acids and endocannabinoidome-related mediator profiles associated to human longevity.

Claudia Manca, Gianfranca Carta, Elisabetta Murru, Armita Abolghasemi, Hastimansooreh Ansar, Alessandra Errigo, Patrice D Cani, Sebastiano Banni, Giovanni Mario Pes

Mentions

127
Peak: 24 in Jan 2023
across 4 sources since Mar 2021

Extended reach

96,453
potential audience

Total likes

292

Video views

10,412

Mentions per month

Mar 2021 – May 2025

Where it's discussed

  • X / Twitter106 posts
  • News17 articles
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The overall tone reflects strong interest and moderate engagement, exemplified by posts mentioning specific fatty acids like conjugated linoleic acid and DHA, and expressions of looking forward to reading the detailed study, such as 'Looking forward to reading it' and 'Thanks. Free, Full Text.' This indicates that users are eager to further understand the research, driven by the significance of metabolic markers linked to longevity.

AgreementModerate agreement

Most discussions acknowledge the publication's findings as relevant, with some expressing anticipation to read more or agree with its implications.

InterestHigh interest

Posts demonstrate high curiosity, referencing specific fatty acids and mediators, and showing eagerness to explore the health benefits discussed.

EngagementModerate engagement

Comments include mentions of detailed biomarkers and potential applications, indicating moderate to high engagement with the technical content.

ImpactModerate impact

The topics could influence ongoing research or dietary considerations, but the discussions suggest a cautious optimism rather than definitive impact.

Abstract in brief

  • The study found that people living in a high-longevity zone in Sardinia, especially older adults, have unique profiles of fatty acids and endocannabinoid-related mediators that might be linked to healthier aging and protection against age-related diseases.
  • Specific fatty acids like conjugated linoleic acid (CLA) and heptadecanoic acid were higher in older adults from the high-longevity zone, while certain endocannabinoids like AEA, 2-AG, and other related compounds also showed elevated levels, suggesting a beneficial metabolic pattern.
  • Overall, these distinctive profiles in both fatty acids and endocannabinoids could serve as biomarkers or targets for understanding how metabolic factors contribute to longevity and prevent conditions like neurodegenerative and metabolic disorders.

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All mentions

C15:0: Impact on Health and Longevity

C15:0, also known as pentadecanoic acid, plays a significant role in health and longevity. This video discusses its implications on human health, with references to various scientific studies illustrating the benefits…

章博士說長壽 · May 11, 2024 5,004 views
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alephh
@alephh · X

Fatty acids in octogenarians: high vs low longevity Zone in Sardinia — Up: conjugated linoleic acid (CLA), heptadecanoic acid (17:0), docosahexaenoic acid (DHA), DHEA, Palmitoleic acid, endocannabinoids N-arachidonoyl-ethanolamine & 2-arachidonoyl-glycerol https://t.co/YhpXY2k159 https://t.co/EeW1AMkED2

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J P Fanton
@HealthyFellow · X

@bioMioSoftware @DCGreenZone1 Looking forward to reading it. Thanks. Free, Full Text: https://t.co/UotvvhiVHM

Mar 16, 2021 · 1 like · 26,014 followers View post →