February 2021 PMID 33652997

Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence.

Cara T Hoepner, Roger S McIntyre, George I Papakostas

Mentions

47
Peak: 19 in Jun 2021
across 4 sources since Feb 2021

Extended reach

510,736
potential audience

Total likes

911

Video views

11,472

Mentions per month

Feb 2021 – Dec 2025

Where it's discussed

  • X / Twitter42 posts
  • YouTube2 videos
  • News2 articles
  • Instagram1 posts

AI synopsis

What people are saying

The overall tone suggests that discussions view the review as an important contribution, with phrases like 'highly cited' and 'beneficial impact,' reflecting high interest and recognition of its relevance. Some comments critique conventional medication approaches, indicating some influence in shaping opinions about nutrition’s role in mood disorder treatment, but most posts serve to disseminate rather than deeply analyze the research.

AgreementModerate agreement

Most discussions reference the review positively, emphasizing its benefits and calling it 'beneficial' and 'highly cited,' reflecting general agreement with its findings.

InterestHigh interest

Several posts highlight the significance of nutrition in mood disorders, indicating high curiosity and recognition of the topic’s relevance.

EngagementModerate engagement

While some posts share personal opinions or critiques, such as concerns over medication and calls for alternative approaches, many focus on summarizing the review’s importance, showing moderate engagement.

ImpactModerate impact

The widespread sharing of the publication’s details and calls to read or discuss it suggest the article is seen as influential, but most reactions stay at the level of reposting without delving into deep changes in perspective.

Abstract in brief

  • This review explores how nutritional supplements and interventions like folate, SAMe, amino acids, vitamins, and minerals can influence the biological processes underlying mood disorders such as depression, highlighting evidence that certain supplements may have antidepressant effects.
  • Abnormal levels of nutrients like folate, homocysteine, and SAMe are linked to a higher risk of depression, and supplements targeting these deficiencies (e.g., L-methylfolate, SAMe) may improve depressive symptoms.
  • Combining antidepressant medications with nutritional supplements (like zinc, omega-3s, or coenzyme Q10) could enhance treatment effectiveness, especially for patients not responding well to standard therapies, though study biases and variations should be considered when interpreting results.]

Top posts

Most liked on X and Bluesky
Atanas G. Atanasov
@_atanas_ · X

Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence #INPST #Nutritional #MoodDisorders https://t.co/ASjRStfOUk

Jun 19, 2021 · 42 likes · 17 shares · 124,474 followers View post →
Nutrients MDPI
@Nutrients_MDPI · X

Read highly cited Paper "Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders" by Ms. Cara T. Hoepner et al. @christian_dkka @dj_surfista @drdingle @evarev1 @MaritaOstos @Truehealthinfo @_atanas_ @chihuu https://t.co/0kXQY2YNiQ https://t.co/KEWX4msn0t

May 10, 2023 · 18 likes · 7 shares · 11,329 followers View post →
Nutrients MDPI
@Nutrients_MDPI · X

Welcome to these highly cited papers! https://t.co/zmCooCiPq4 https://t.co/Tk8cU6ncS7 https://t.co/qt0r07oT9Y https://t.co/ig4biXhh6G https://t.co/BayByZ6AcV https://t.co/1c0R22MTO3 https://t.co/p5NlIq8wqZ https://t.co/htNnaO97JN https://t.co/Z0lvT9H2hl https://t.co/hKH5XgeUNc https://t.co/t4Avm1mrYi

Nov 28, 2023 · 3 likes · 1 share · 11,329 followers View post →
Professor George
@ChiilesheGeorge · X

@WealthFitLife Also, https://t.co/u8jeCTNTV8 It can be as simple as, 1. Walking in the SUN

Aug 5, 2022 · 2 likes · 4,979 followers View post →
Professor George
@ChiilesheGeorge · X

@ChrisPalmerMD @robertlufkinmd https://t.co/u8jeCTNTV8 Dealing with depression and anxiety is as simple as 1. Walking in the SUN

Aug 28, 2022 · 1 like · 4,979 followers View post →
Peter Dingle (PhD)
@drdingle · X

Beneficial Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence https://t.co/BFJAHTVLla via @MDPIOpenAccess

Mar 27, 2021 · 1 like · 2,286 followers View post →

All mentions

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vilarino7734163
@vilarino7734163 · X

https://t.co/XTq56435uw

Nov 24, 2025 · 95 followers View post →
Beth S. Sanford, DNP
@DNP4VitaminD · X

RT @Nutrients_MDPI: Welcome to these highly cited papers! https://t.co/zmCooCiPq4 https://t.co/Tk8cU6ncS7 https://t.co/qt0r07oT9Y https://t…

Nov 28, 2023 · 1 share · 199 followers View post →
Nutrients MDPI
@Nutrients_MDPI · X

Welcome to these highly cited papers! https://t.co/zmCooCiPq4 https://t.co/Tk8cU6ncS7 https://t.co/qt0r07oT9Y https://t.co/ig4biXhh6G https://t.co/BayByZ6AcV https://t.co/1c0R22MTO3 https://t.co/p5NlIq8wqZ https://t.co/htNnaO97JN https://t.co/Z0lvT9H2hl https://t.co/hKH5XgeUNc https://t.co/t4Avm1mrYi

Nov 28, 2023 · 3 likes · 1 share · 11,329 followers View post →
.c.a.r.l.o.s
@galantee28 · X

RT @Nutrients_MDPI: Read highly cited Paper "Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disord…

May 18, 2023 · 7 shares · 35 followers View post →
Bongani Mayosi Health Sciences Library (BMHSL)
@uct_bmhsl · X

RT @Nutrients_MDPI: Read highly cited Paper "Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disord…

May 11, 2023 · 7 shares · 1,591 followers View post →
International Natural Product Sciences Taskforce
@_INPST · X

RT @Nutrients_MDPI: Read highly cited Paper "Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disord…

May 11, 2023 · 7 shares · 10,287 followers View post →
Science Communication
@ScienceCommuni2 · X

RT @Nutrients_MDPI: Read highly cited Paper "Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disord…

May 11, 2023 · 7 shares · 2,889 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @Nutrients_MDPI: Read highly cited Paper "Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disord…

May 11, 2023 · 7 shares · 124,474 followers View post →
NutriAle_Coach
@NutriAle_Coach · X

RT @Nutrients_MDPI: Read highly cited Paper "Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disord…

May 10, 2023 · 7 shares · 1,551 followers View post →
BANT
@BANTonline · X

RT @Nutrients_MDPI: Read highly cited Paper "Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disord…

May 10, 2023 · 7 shares · 7,660 followers View post →
EVA REVE
@evarev1 · X

RT @Nutrients_MDPI: Read highly cited Paper "Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disord…

May 10, 2023 · 7 shares View post →
Nutrients MDPI
@Nutrients_MDPI · X

Read highly cited Paper "Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders" by Ms. Cara T. Hoepner et al. @christian_dkka @dj_surfista @drdingle @evarev1 @MaritaOstos @Truehealthinfo @_atanas_ @chihuu https://t.co/0kXQY2YNiQ https://t.co/KEWX4msn0t

May 10, 2023 · 18 likes · 7 shares · 11,329 followers View post →
Zuzička
@noonespecial000 · X

@GigiBowman @e_liz82 @catsscareme2021 I am so sorry for your loss. Drugs like these almost killed me. They are poison and are evil. There is no informed consent, just the “benefits” which are no better than changing ones diet. But they would rather have the youth population drugged. https://t.co/SOC6Y4qj5j

Apr 6, 2023 · 1 like · 486 followers View post →
molina molina
@molinam36323338 · X

@AshMD_1 https://t.co/hXth0FekCF https://t.co/ZkBVem7KfG

Nov 8, 2022 · 79 followers View post →
Professor George
@ChiilesheGeorge · X

@ChrisPalmerMD @robertlufkinmd https://t.co/u8jeCTNTV8 Dealing with depression and anxiety is as simple as 1. Walking in the SUN

Aug 28, 2022 · 1 like · 4,979 followers View post →
Professor George
@ChiilesheGeorge · X

https://t.co/u8jeCTNTV8 Dealing with depression and anxiety is as simple as 1. Walking in the SUN

Aug 18, 2022 · 4,979 followers View post →
Professor George
@ChiilesheGeorge · X

@WealthFitLife Also, https://t.co/u8jeCTNTV8 It can be as simple as, 1. Walking in the SUN

Aug 5, 2022 · 2 likes · 4,979 followers View post →
Dr. LoBisco
@DrLoBisco · X

Impact of #supplementation and #nutritional Interventions on Pathogenic Processes of #mood Disorders: A Review of the Evidence: https://t.co/B9MmHKDrXD

May 27, 2022 · 968 followers View post →
krs
@Tonnimon · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 21, 2021 · 17 shares · 37 followers View post →
Dra. Teraiza Mesa R Cuenta Oficial ®
@Dra_TeraizaMesa · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence #INPST #Nutritional #MoodDisorders https://t.co/8sIvIZjsgr

Jun 21, 2021 · 9,030 followers View post →
Ronita De, PhD
@dronita_de · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 21, 2021 · 17 shares · 1,512 followers View post →
Fabrice Leclerc
@leclercfl · X

Top #science story: Nutrients | Free Full-Text | Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence https://t.co/MZCL5nCog6, see more https://t.co/zYmGuZ3rN9

Jun 20, 2021 · 1,447 followers View post →
Banquo's ghost
@peteraf1 · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 20, 2021 · 17 shares · 5,028 followers View post →
Imperator of Antarctica
@IndolentCoward · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 20, 2021 · 17 shares · 256 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 20, 2021 · 17 shares · 124,474 followers View post →
Climate46304220
@Climate46304220 · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 19, 2021 · 17 shares · 397 followers View post →
World Citizen
@Uranian39 · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 19, 2021 · 17 shares · 1,316 followers View post →
Science Communication
@ScienceCommuni2 · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 19, 2021 · 17 shares · 2,889 followers View post →
sciencenews
@Scieducation1 · X

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Jun 19, 2021 · 17 shares · 5,129 followers View post →
Chris Ngo
@CNigaud · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 19, 2021 · 17 shares · 711 followers View post →
Stephen Norris
@1_StephenNorris · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 19, 2021 · 17 shares · 1,646 followers View post →
International Natural Product Sciences Taskforce
@_INPST · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 19, 2021 · 17 shares · 10,287 followers View post →
Juan Solìs
@aajuansolisaa · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 19, 2021 · 17 shares · 355 followers View post →
Omi
@Omi_082 · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 19, 2021 · 17 shares · 3,293 followers View post →
Sofia
@MariadeliaSofia · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 19, 2021 · 17 shares · 10,930 followers View post →
Kimmo H
@chihuu · X

RT @_atanas_: Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence…

Jun 19, 2021 · 17 shares · 3,346 followers View post →
Atanas G. Atanasov
@_atanas_ · X

Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence #INPST #Nutritional #MoodDisorders https://t.co/ASjRStfOUk

Jun 19, 2021 · 42 likes · 17 shares · 124,474 followers View post →
True Health
@Truehealthinfo · X

Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence https://t.co/iYlafBH3lP

Apr 27, 2021 · 867 followers View post →
Marita Ostos
@MaritaOstos · X

Nutrients | Free Full-Text | Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence https://t.co/vYPXj7pfkb

Mar 29, 2021 · 158 followers View post →
EVA REVE
@evarev1 · X

RT @drdingle: Beneficial Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the…

Mar 27, 2021 View post →
Peter Dingle (PhD)
@drdingle · X

Beneficial Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence https://t.co/BFJAHTVLla via @MDPIOpenAccess

Mar 27, 2021 · 1 like · 2,286 followers View post →
Maurício Lima
@dj_surfista · X

Impacto da suplementação e intervenções nutricionais nos processos patogênicos dos transtornos do humor: uma revisão das evidências. https://t.co/XDq705Uahr

Feb 26, 2021 · 1 like · 749 followers View post →
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